المؤلفون: Alaa A. A. Aljabali, Nitin Charbe, Poonam Negi, Nikhil D. Amnerkar, Gaurav Gupta, B. Ramesh, Meenu Metha, Hamid A. Bakshi, Dinesh Kumar Chellappan, Saurabh C. Khadse, Garima Shrivastava, Saurabh Satija, Kamal Dua, Flavia C. Zacconi, Murtaza M. Tambuwala, Rajendran Satheeshkumar

المصدر: Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: Small interfering RNA, PE-PCL-b-PNVCL, pentaerythritol polycaprolactone-block-poly(N-vinylcaprolactam), DSPE-MPEG, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt), Review, 0302 clinical medicine, micro RNA, MPEG, poly(ethylene glycol)-block-poly(l-lysine), PEI, General Pharmacology, Toxicology and Pharmaceutics, Polymer, Micelles, Cancer, DOPC, dioleylphosphatidyl choline, DSPE-PEG-Mal: 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-2000] (mmmonium salt), EPR, 0303 health sciences, poly(acrylhydrazine)-block-poly(3-dimethylaminopropyl methacrylamide)-block-poly(acrylhydrazine), PCL, S–Au, thio‒gold, AQP-5, aquaporin-5, CMC, critical micelles concentration, DOTAP, N-[1-(2,3-dioleoyloxy)propyl]-N,N,N-trimethylammonium methyl-sulfate, Cancer treatment, APOB, apolipoprotein B, Nanomedicine, RNAi, RNA interference, poly(ethylene glycol)-block-poly(2-dimethylaminoethyl methacrylate)-block poly(pyrenylmethyl methacrylate), PEG-b-PLL, 030220 oncology & carcinogenesis, B-PEI, branched polyethlenimine, Atufect01, β-l-arginyl-2,3-l-diaminopropionicacid-N-palmityl-N-oleyl-amide trihydrochloride, CHEMS, cholesteryl hemisuccinate, DSGLA, N,N-dis-tearyl-N-methyl-N-2[N′-(N2-guanidino-l-lysinyl)] aminoethylammonium chloride, SEM, scanning electron microscope, messenger RNA, MTX, polycaprolactone-polyethylenimine, PDMA, BMA, butyl methacrylate, 03 medical and health sciences, TCC - Transitional cell carcinoma, RNAse III, ribonuclease III enzyme, methotrexate, NIR, ZEBOV, Zaire ebola virus, DSPC, 1,2-distearoyl-sn-glycero-3-phosphocholine, lysine ethyl ester diisocyanate, LPD/LPH, poly(N-isopropyl acrylamide), pentaerythritol polycaprolactone-block-poly(N-isopropylacrylamide), medicine.disease, CFTR, cystic fibrosis transmembrane conductance regulator gene, UV, ultraviolet, Cancer cell, Liposomes, PPES-b-PEO-b-PPES, poly(4-(phenylethynyl)styrene)-block-PEO-block-poly(4-(phenylethynyl)styrene), RES, reticuloendothelial system, hypoxia-inducible factor-1α, KSP, DMAEMA, 2-dimethylaminoethyl methacrylate, N-acetylgalactosamine, HIF-1α, DNA, deoxyribonucleic acid, USPIO, ultra-small superparamagnetic iron oxide nanoparticles, enhanced permeability and retention, Galnac, RISC, RNA-induced silencing complex, nanoparticle, NRP-1, near-infrared, NP, methoxypoly(ethylene glycol), MPEG-PCL, 1,3-propanediol, PEG-b-PDMAEMA-b-Ppy, neuropilin-1, PAA, PLGA, poly lactic-co-glycolic acid, methoxy polyethylene glycol-polycaprolactone, mRNA, poly(N,N-dimethylacrylamide), PDO, VEGF, vascular endothelial growth factor, PLL, poly-l-lysine, lipid-protamine-DNA/hyaluronic acid, MDR, DSPE, 1,2-distearoyl-sn-glycero-3-phosphorylethanolamine, Drug delivery, RGD, Arg-Gly-Asp peptide, SNALP, stable nucleic acid-lipid particles, poly(Ε-caprolactone)-polyethyleneglycol-poly(l-histidine), PCL-PEI, DOTMA, N-[1-(2,3-dioleyloxy)propy]-N,N,N-trimethylammoniumchloride, kinesin spindle protein, LDI, Small interfering RNA (siRNA), 2-propylacrylicacid, PAH-b-PDMAPMA-b-PAH, AZEMA, azidoethyl methacrylate, poly(ethylene oxide)-block-poly(2-(diethylamino)ethyl methacrylate)-stat-poly(methoxyethyl methacrylate), PEO-b-PCL, AuNPs, gold nanoparticles, TCC, transitional cell carcinoma, Tf, transferrin, medicine, multiple drug resistance, MiRNA, TEM, transmission electron microscopy, 030304 developmental biology, PLK-1, polo-like kinase 1, poly(ethylene oxide)-block-poly(Ε-caprolactone), PE-PCL-b-PNIPAM, poly(Ε-caprolactone), PCL-PEG, CHOL, cholesterol, PLA, poly-l-arginine, DC-Chol, 3β-[N-(N′,N′-dimethylaminoethane)carbamoyl]cholesterol, Trka, tropomyosin receptor kinase A, polyethylenimine, PEO-b-P(DEA-Stat-MEMA, DOX, doxorubicin, polycaprolactone-polyethyleneglycol, PCL-PEG-PHIS, DOPE, dioleylphosphatidyl ethanolamine, PTX, paclitaxel, PiRNA, piwi-interacting RNA, Cancer research, RNA, ribonucleic acid, SiRNA, short interfering rNA, Nanocarriers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2071f422f1c1f8a688b18780d3afbc9c
https://pubmed.ncbi.nlm.nih.gov/33304780

المؤلفون: Satheeswaran Balasubramanian, Ekambaram Perumal, Vignesh Jeyamanickavel Mathan, Kanmani Gunasekaran, Saranyadevi Sasidharan

المصدر: Toxicology Reports
Toxicology Reports, Vol 7, Iss, Pp 583-595 (2020)

مصطلحات موضوعية: microRNAs: Potential biomarkers of toxicity, Nrf2, Nuclear factor erythroid 2-related factor 2, Aβ, Amyloid Beta, Toxicology, 01 natural sciences, Non-coding RNAs, AHR, Aryl Hydrocarbon Receptor, 0302 clinical medicine, CDK6, Cyclin-dependent kinase 6, NMDAR, N-methyl-d-aspartate receptor, TP53, Tumor protein 53, BaP, Benzo[a]pyrene, NPs, Nanoparticles, Regulation of gene expression, Hpf, Hours post fertilization, qRT-PCR, quantitative Real Time-Polymerase Chain Reaction, CDKN1b, Cyclin-dependent kinase Inhibitor 1B, Wnt, Wingless-related integration site, HSPA1A, Heat shock 70 kDa protein 1, IL1R1, Interleukin 1 receptor, type 1, ER, Endoplasmic Reticulum, PDCD4, Programmed cell death protein 4, MC-RR, Microcystin-Arginine Arginine, RNAi, RNA interference, DGCR8, DiGeorge syndrome chromosomal [or critical] region 8, Epigenetics, GTP, Guanosine triphosphate, bcl2l11, B-cell lymphoma-2-like protein 11, TCDD, 2,3,7,8-Tetrachlorodibenzodioxin, RNA - Ribonucleic acid, lncRNAs, Long non-coding RNA, NFKBAP, NFKB Activating protein-1, COPD, Chronic obstructive pulmonary disease, PM2.5, Particulate Matter2.5, Environment, WHO, World Health Organization, 03 medical and health sciences, MRE, MicroRNA Response Elements, microRNA, SPIONs, Superparamagnetic Iron Oxide Nanoparticles, AMPK, Adenosine Monophosphate-activated protein kinase, lcsh:Toxicology. Poisons, NASH, Non-alcoholic steatohepatitis, CDK, Cyclin-dependent Kinase, CEC, Contaminants of Emerging Concern, RNase III, Ribonuclease III, LRP-1-, Low density lipoprotein receptor-related protein 1, MC-LR, Microcystin-Leucine Arginine, CCNB1, Cyclin B1, Ag, Silver, SiO2, Silicon dioxide, chemistry, LIN28B, Lin-28 homolog B, TRBP, Transactivation Response RNA Binding Protein, 030217 neurology & neurosurgery, Ahr aryl hydrocarbon receptor, Biomarkers, COX2, Cyclooxygenase-2, Au, Gold, ZEA, Zearalanone, Mn, Manganese, NF- ҡB, Nuclear Factor kappa-light-chain-enhancer of activated B cells, Health, Toxicology and Mutagenesis, Grp78/BIP, Binding immunoglobulin protein, 010501 environmental sciences, UTR, Untranslated region, chemistry.chemical_compound, ARRB1, Arrestin beta 1, RISC, RNA-induced silencing complex, Zn, Zinc, CTGF, Connective Tissue Growth Factor, NET1, Neuroepithelial Cell Transforming 1, BNIP3−3, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3, DNA, Deoxy ribonucleic acid, PFAS, Poly-fluoroalkyl substances, mRNA, Messenger RNA, ripk 1, Receptor-interacting serine/threonine-protein kinase 1, Toxicity, Fadd, Fas-associated protein with death domain, IL-6, Interleukin 6, SOLiD, Sequencing by Oligonucleotide Ligation and Detection, Al2O3, Aluminium oxide, ceRNA, Competing endogenous RNA, Computational biology, Biology, SEMA6D, Semaphorin-6D, BCB, Blood-cerebrospinal fluid barrier, ADAMTS9, A disintegrin and metalloproteinase with thrombospondin motifs 9, CDC25A, M-phase inducer phosphatase 1, lcsh:RA1190-1270, CDK1, Cyclin-dependent kinase 1, DON, Deoxynivalenol, RNA, Ribonucleic acid, TNF-α, Tumor necrosis factor – alpha, 0105 earth and related environmental sciences, ComputingMethodologies_COMPUTERGRAPHICS, miRNA, MicroRNA, MAPK, Mitogen Activated Protein Kinase, Gene regulation, CDC25C, M-phase inducer phosphatase 3, Xenobiotic, MiRNA biogenesis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d9ee14a85356d66a24aeb2b5ac399f7
https://pubmed.ncbi.nlm.nih.gov/32426239

المؤلفون: Ray K.M. Leung, Paul A. Whittaker

المصدر: Pharmacology & Therapeutics

مصطلحات موضوعية: Small interfering RNA, K-Ras, c-Kirsten-ras protein, Respiratory Tract Diseases, MIP2, macrophage inflammatory protein-2, MDR, multidrug-resistance protein, miRNA, microRNAs, ABCA1, ATP-binding cassette, subfamily A, member 1, Small hairpin RNA, AAV, adeno-associated virus, shRNA, RNA interference, Neoplasms, Validation, CXCR4, chemokine (C–X–C motif), receptor 4, RasGAP, Ras GTPase-activating protein, RISC, RNA-induced silencing complex, TGFβ, transforming growth factor β, Disease, CML, chronic myelogenous leukemia, Pharmacology (medical), RNA, Small Interfering, Genetics, Gene knockdown, RdDM, RNA-directed DNA methylation, CD8, T-lymphocyte differentiation antigen T8/Leu-2, smad 7, mothers against decapentaplegic homolog 7, VEGF, vascular endothelial growth factor, Cell biology, HIV, human immunodeficiency virus, LoxP, locus χ of crossover P1, RNA silencing, RNAi, RNA interference, Rnase III, ribonuclease III, SCID, severe combined immunodeficiency, HCV, hepatitis C virus, TNFα, tumour necrosis factor α, EpCAM, tumour-associated calcium signal transducer 1, S1P, sphingosine 1-phosphate, shRNA, short hairpin RNA, LPS, lipopolysaccharide, RNA Interference, TGFα, transforming growth factor α, TLR3, toll-like receptor 3, Cre, causes recombination, LacZ, β-galactosidase α-peptide, CCR5, chemokine (C–C motif) receptor 5, Biology, KC, keratinocyte-derived chemokine, Communicable Diseases, Article, LNA, locked nucleic acid, NF-κB, Nuclear factor-kappaB, B-RAF, murine sarcoma viral (v-raf) oncogene homolog B1 oncogene, Fas, tumour necrosis factor receptor superfamily, member 6, microRNA, Animals, Humans, BCR-ABL, breakpoint cluster region-protooncogene tyrosine-protein kinase ABL1 fusion protein, Gene silencing, IFN, interferon, Gene Silencing, SARS, severe acute respiratory syndrome, PEG, polyethylene glycol, PEI, polyethyleneimine, Pharmacology, Bcl-2, B-cell chronic lymphocytic leukemia/lymphoma 2, EC, endothelial cell, BMP4, bone morphogenetic protein 4, RNA, EGFR, epidermal growth factor receptor, bp, base pairs, PKR, dsRNA-dependent protein kinase, HBV, hepatitis B virus, COPD, chronic obstructive pulmonary disease, siRNA, small interfering RNA, Drug Design, RNAi, siRNA, dsRNA, double-stranded RNA, Therapy, RSV, respiratory syncytial virus, ERK, extracellular signal regulated protein kinase, smad 1, mothers against decapentaplegic homolog 1, MAPK, mitogen-activated protein kinase, HMG-CoA, beta-hydroxy-beta-methylglutaryl coenzyme A

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dee73333d21169d5133ab57939122a4
https://doi.org/10.1016/j.pharmthera.2005.03.004

المؤلفون: Cecília M. Arraiano, Nabila Haddad, Margarida Saramago, Hervé Prévost, Rute G. Matos

المساهمون: UMR 1014 SECurité des ALIments et Microbiologie, Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Vétérinaire, Agroalimentaire et de l'alimentation Nantes-Atlantique (ONIRIS), Universidade Nova de Lisboa = NOVA University Lisbon (NOVA), Region Pays de la Loire through the programme grant GENICAMP, GENICAMP programme, Institut National de la Recherche Agronomique and Region des Pays de la Loire, Fundacao para a Ciencia e Tecnologia (FCT) [PEst-OE/EQB/LA0004/2011, PTDC/QUI-BIQ/111757/2009], FCT [SFRH/BD/65607/2009, SFRH/BPD/75887/2011]

المصدر: Bioscience Reports
Bioscience Reports, Portland Press, 2013, 33 (6), pp.889-901. ⟨10.1042/BSR20130090⟩
Bioscience Reports 6 (33), 889-901. (2013)
Bioscience Reports, Vol 33, Iss 6, p e00082 (2013)

مصطلحات موضوعية: Ribonuclease III, RNase III, Cj-RNase III, C. jejuni RNase III, [SDV]Life Sciences [q-bio], lcsh:Life, lcsh:QR1-502, dsRBD, dsRNA binding domain, DSS, disuccinimidyl suberate, medicine.disease_cause, Biochemistry, RNase PH, RNase III, ribonuclease III, lcsh:Microbiology, Enzyme Stability, Magnesium, Conserved Sequence, Phylogeny, 0303 health sciences, biology, Hydrogen-Ion Concentration, Ec-RNase III, E. coli RNase III, RNA, Bacterial, LB, Luria–Bertani, manganese, ribonuclease, wt, wild-type, Molecular Sequence Data, Biophysics, catalytic activity, Campylobacter jejuni, S2, Microbiology, 03 medical and health sciences, Bacterial Proteins, medicine, Escherichia coli, Ribonuclease, Polynucleotide phosphorylase, Amino Acid Sequence, RRNA processing, Protein Structure, Quaternary, Molecular Biology, 030304 developmental biology, RNA Cleavage, Original Paper, Base Sequence, 030306 microbiology, Genetic Complementation Test, Cell Biology, biology.organism_classification, PNPase, polynucleotide phosphorylase, cpm, counts/min, RNase MRP, lcsh:QH501-531, Amino Acid Substitution, DTT, dithiothreitol, RNA, Ribosomal, biology.protein, Mutagenesis, Site-Directed, Calcium

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97f605e6af3db686457b4409b63c48f5
https://hal.inrae.fr/hal-02646558/file/Haddad_2013_1.pdf

المؤلفون: Charbe NB; Departamento de Quimica Orgánica, Facultad de Química y de Farmacia, Pontificia Universidad Católica de Chile, Santiago 7820436, Chile.; Sri Adichunchunagiri College of Pharmacy, Sri Adichunchunagiri University, BG Nagar, Karnataka 571418, India., Amnerkar ND; Adv V. R. Manohar Institute of Diploma in Pharmacy, Nagpur, Maharashtra 441110, India., Ramesh B; Sri Adichunchunagiri College of Pharmacy, Sri Adichunchunagiri University, BG Nagar, Karnataka 571418, India., Tambuwala MM; School of Pharmacy and Pharmaceutical Science, Ulster University, Coleraine, Northern Ireland BT52 1SA, UK., Bakshi HA; School of Pharmacy and Pharmaceutical Science, Ulster University, Coleraine, Northern Ireland BT52 1SA, UK., Aljabali AAA; Faculty of Pharmacy, Department of Pharmaceutics and Pharmaceutical Technology, Yarmouk University, Irbid 21163, Jordan., Khadse SC; Department of Pharmaceutical Chemistry, R.C. Patel Institute of Pharmaceutical Education and Research, Dist. Dhule, Maharashtra 425 405, India., Satheeshkumar R; Departamento de Quimica Orgánica, Facultad de Química y de Farmacia, Pontificia Universidad Católica de Chile, Santiago 7820436, Chile., Satija S; Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, NSW 2007, Australia.; School of Pharmaceutical Sciences, Lovely Professional University, Phagwara 144411 Punjab, India., Metha M; Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, NSW 2007, Australia.; School of Pharmaceutical Sciences, Lovely Professional University, Phagwara 144411 Punjab, India., Chellappan DK; Department of Life Sciences, School of Pharmacy, International Medical University, Bukit Jalil 57000, Kuala Lumpur, Malaysia., Shrivastava G; Department of Biochemical Engineering and Biotechnology, Indian Institute of Technology, Delhi, New Delhi 110016, India., Gupta G; School of Pharmacy, Suresh Gyan Vihar University, Jagatpura, Jaipur 302017, India., Negi P; School of Pharmaceutical Sciences, Shoolini University of Biotechnology and Management Sciences, Solan 173229, India., Dua K; Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, NSW 2007, Australia.; School of Pharmaceutical Sciences, Shoolini University of Biotechnology and Management Sciences, Solan 173229, India.; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute (HMRI) and School of Biomedical Sciences and Pharmacy, University of Newcastle, NSW 2308, Australia., Zacconi FC; Departamento de Quimica Orgánica, Facultad de Química y de Farmacia, Pontificia Universidad Católica de Chile, Santiago 7820436, Chile.; Institute for Biological and Medical Engineering, Schools of Engineering, Medicine and Biological Sciences, Pontificia Universidad Católica de Chile, Santiago 4860, Chile.

المصدر: Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2020 Nov; Vol. 10 (11), pp. 2075-2109. Date of Electronic Publication: 2020 Oct 13.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101600560 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2211-3835 (Print) Linking ISSN: 22113835 NLM ISO Abbreviation: Acta Pharm Sin B Subsets: PubMed not MEDLINE

المؤلفون: Balasubramanian S; Molecular Toxicology Laboratory, Department of Biotechnology, Bharathiar University, Coimbatore, 641 046, India., Gunasekaran K; Molecular Toxicology Laboratory, Department of Biotechnology, Bharathiar University, Coimbatore, 641 046, India., Sasidharan S; Molecular Toxicology Laboratory, Department of Biotechnology, Bharathiar University, Coimbatore, 641 046, India., Jeyamanickavel Mathan V; Molecular Toxicology Laboratory, Department of Biotechnology, Bharathiar University, Coimbatore, 641 046, India., Perumal E; Molecular Toxicology Laboratory, Department of Biotechnology, Bharathiar University, Coimbatore, 641 046, India.

المصدر: Toxicology reports [Toxicol Rep] 2020 May 04; Vol. 7, pp. 583-595. Date of Electronic Publication: 2020 May 04 (Print Publication: 2020).

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier Ireland Ltd Country of Publication: Ireland NLM ID: 101630272 Publication Model: eCollection Cited Medium: Internet ISSN: 2214-7500 (Electronic) Linking ISSN: 22147500 NLM ISO Abbreviation: Toxicol Rep Subsets: PubMed not MEDLINE