يعرض 1 - 10 نتائج من 16 نتيجة بحث عن '"ROMINES, K. R."', وقت الاستعلام: 0.93s تنقيح النتائج
  1. 1
    دورية
    Novel Benzophenones as Non-nucleoside Reverse Transcriptase Inhibitors of HIV-1

    المؤلفون: Chan, J. H., Freeman, G. A., Tidwell, J. H., Romines, K. R., Schaller, L. T., Cowan, J. R., Gonzales, S. S., Lowell, G. S., Andrews, C. W., III, Reynolds, D. J., Clair, M. St, Hazen, R. J., Ferris, R. G., Creech, K. L., Roberts, G. B., Short, S. A., Weaver, K., Koszalka, G. W., Boone, L. R.

    المصدر: Journal of Medicinal Chemistry; February 2004, Vol. 47 Issue: 5 p1175-1182, 8p

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  2. 2
    دورية
    Structure-Based Design of Nonpeptidic HIV Protease Inhibitors:  The Sulfonamide-Substituted Cyclooctylpyranones

    المؤلفون: Skulnick, H. I., Johnson, P. D., Aristoff, P. A., Morris, J. K., Lovasz, K. D., Howe, W. J., Watenpaugh, K. D., Janakiraman, M. N., Anderson, D. J., Reischer, R. J., Schwartz, T. M., Banitt, L. S., Tomich, P. K., Lynn, J. C., Horng, M.-M., Chong, K.-T., Hinshaw, R. R., Dolak, L. A., Seest, E. P., Schwende, F. J., Rush, B. D., Howard, G. M., Toth, L. N., Wilkinson, K. R., Kakuk, T. J., Johnson, C. W., Cole, S. L., Zaya, R. M., Zipp, G. L., Possert, P. L., Dalga, R. J., Zhong, W.-Z., Williams, M. G., Romines, K. R.

    المصدر: Journal of Medicinal Chemistry; March 28, 1997, Vol. 40 Issue: 7 p1149-1164, 16p

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  3. 3
    دورية
    Structure-Based Design of HIV Protease Inhibitors:  Sulfonamide-Containing 5,6-Dihydro-4-hydroxy-2-pyrones as Non-Peptidic Inhibitors

    المؤلفون: Thaisrivongs, S., Skulnick, H. I., Turner, S. R., Strohbach, J. W., Tommasi, R. A., Johnson, P. D., Aristoff, P. A., Judge, T. M., Gammill, R. B., Morris, J. K., Romines, K. R., Chrusciel, R. A., Hinshaw, R. R., Chong, K.-T., Tarpley, W. G., Poppe, S. M., Slade, D. E., Lynn, J. C., Horng, M.-M., Tomich, P. K., Seest, E. P., Dolak, L. A., Howe, W. J., Howard, G. M., Schwende, F. J., Toth, L. N., Padbury, G. E., Wilson, G. J., Shiou, L., Zipp, G. L., Wilkinson, K. F., Rush, B. D., Ruwart, M. J., Koeplinger, K. A., Zhao, Z., Cole, S., Zaya, R. M., Kakuk, T. J., Janakiraman, M. N., Watenpaugh, K. D.

    المصدر: Journal of Medicinal Chemistry; October 25, 1996, Vol. 39 Issue: 22 p4349-4353, 5p

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  4. 4
    دورية
    Cycloalkylpyranones and Cycloalkyldihydropyrones as HIV Protease Inhibitors:  Exploring the Impact of Ring Size on Structure−Activity Relationships

    المؤلفون: Romines, K. R., Morris, J. K., Howe, W. J., Tomich, P. K., Horng, M.-M., Chong, K.-T., Hinshaw, R. R., Anderson, D. J., Strohbach, J. W., Turner, S. R., Mizsak, S. A.

    المصدر: Journal of Medicinal Chemistry; September 27, 1996, Vol. 39 Issue: 20 p4125-4130, 6p

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  5. 5
    دورية أكاديمية
    ChemInform Abstract: Direct Synthesis of Furans by (3 + 2) Cycloadditions Between Rhodium(II) Acetate Stabilized Carbenoids and Acetylenes.

    المؤلفون: DAVIES, H. M. L., ROMINES, K. R.

    المصدر: ChemInform; Nov1988, Vol. 19 Issue 44, pno-no, 2p

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  6. 6
    دورية أكاديمية
    ChemInform Abstract: Novel Approach to Seven-Membered Rings by the Intramolecular Tandem Cyclopropanation/Cope Rearrangement Sequence.

    المؤلفون: DAVIES, H. M. L., OLDENBURG, C. E. M., MCAFEE, M. J., NORDAHL, J. G., HENRETTA, J. P., ROMINES, K. R.

    المصدر: ChemInform; Jul1988, Vol. 19 Issue 30, pno-no, 2p

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  7. 7
    دورية أكاديمية
    ChemInform Abstract: Asymmetric Syntheses and Absolute Stereochemistry of 5,6-Dihydro-α-pyrones, a New Class of Potent HIV Protease Inhibitors.

    المؤلفون: JUDGE, T. M., PHILLIPS, G., MORRIS, J. K., LOVASZ, K. D., ROMINES, K. R., LUKE, G. P., TULINSKY, J., TUSTIN, J. M., CHRUSCIEL, R. A., DOLAK, L. A., MIZSAK, S. A., WATT, W., MORRIS, J., VANDER VELDE, S. L., STROHBACH, J. W., GAMMILL, R. B.

    المصدر: ChemInform; Aug1997, Vol. 28 Issue 32, pno-no, 1p

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  8. 8
    دورية أكاديمية
    ChemInform Abstract: Structure-Based Design of Nonpeptidic HIV Protease Inhibitors from a Cyclooctylpyranone Lead Structure.

    المؤلفون: ROMINES, K. R., WATENPAUGH, K. D., HOWE, W. J., TOMICH, P. K., LOVASZ, K. D., MORRIS, J. K., JANAKIRAMAN, M. N., LYNN, J. C., HORNG, M.-M., CHONG, K.-T., HINSHAW, R. R., DOLAK, L. A.

    المصدر: ChemInform; Mar1996, Vol. 27 Issue 10, pno-no, 1p

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  9. 9
    دورية أكاديمية
    Cycloalkylpyranones and cycloalkyldihydropyrones as HIV protease inhibitors: exploring the impact of ring size on structure-activity relationships.

    المؤلفون: Romines KR; Pharmacia and Upjohn, Inc., Kalamazoo, Michigan 49001, USA., Morris JK, Howe WJ, Tomich PK, Horng MM, Chong KT, Hinshaw RR, Anderson DJ, Strohbach JW, Turner SR, Mizsak SA

    المصدر: Journal of medicinal chemistry [J Med Chem] 1996 Sep 27; Vol. 39 (20), pp. 4125-30.

    نوع المنشور: Journal Article

    بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print Cited Medium: Print ISSN: 0022-2623 (Print) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

    مواضيع طبية MeSH: Anti-HIV Agents/*chemical synthesis , HIV Protease Inhibitors/*chemical synthesis , Pyrones/*chemistry, Anti-HIV Agents/metabolism ; Anti-HIV Agents/pharmacology ; Aspartic Acid Endopeptidases/antagonists & inhibitors ; Aspartic Acid Endopeptidases/chemistry ; Aspartic Acid Endopeptidases/metabolism ; Binding Sites ; Crystallography, X-Ray ; Cyclization ; HIV Protease ; HIV Protease Inhibitors/metabolism ; HIV Protease Inhibitors/pharmacology ; Models, Molecular ; Molecular Structure ; Protein Conformation ; Pyrones/metabolism ; Pyrones/pharmacology ; Structure-Activity Relationship ; Sulfonamides/chemistry

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  10. 10
    دورية أكاديمية
    Structure-based design of nonpeptidic HIV protease inhibitors from a cyclooctylpyranone lead structure.

    المؤلفون: Romines KR; Structural, Analytical, and Medicinal Chemistry Research, Upjohn Laboratories, Kalamazoo, Michigan 49001, USA., Watenpaugh KD, Howe WJ, Tomich PK, Lovasz KD, Morris JK, Janakiraman MN, Lynn JC, Horng MM, Chong KT, et. al.

    المصدر: Journal of medicinal chemistry [J Med Chem] 1995 Oct 27; Vol. 38 (22), pp. 4463-73.

    نوع المنشور: Journal Article

    بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print Cited Medium: Print ISSN: 0022-2623 (Print) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

    مواضيع طبية MeSH: HIV Protease Inhibitors/*chemical synthesis , Pyrones/*chemical synthesis, Aspartic Acid Endopeptidases/antagonists & inhibitors ; Aspartic Acid Endopeptidases/chemistry ; Aspartic Acid Endopeptidases/metabolism ; Computer Graphics ; Crystallography, X-Ray ; Drug Design ; HIV Protease/chemistry ; HIV Protease/metabolism ; HIV Protease Inhibitors/chemistry ; HIV Protease Inhibitors/pharmacology ; Magnetic Resonance Spectroscopy ; Models, Molecular ; Molecular Structure ; Pyrones/chemistry ; Pyrones/pharmacology

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