المؤلفون: Babiker, Hani^{Aff1, IDs10637021011649_cor1}, Schlegel, Peter J., Hicks, Lee G., Bullock, Andrea J., Burhani, Nafisa, Mahadevan, Daruka, Elquza, Emad, Borad, Mitesh J., Benaim, Ely, Peterson, Christine, Heaton, Callie, Ocean, Allyson J.

المصدر: Investigational New Drugs: Novel Anti-Cancer Therapeutics and Therapies. 40(1):81-90

المؤلفون: Dzjemma Sarkisjan, Joris R. Julsing, Btissame El Hassouni, Richard J. Honeywell, Ietje Kathmann, Larry H. Matherly, Young B. Lee, Deog J. Kim, Godefridus J. Peters

المصدر: International Journal of Molecular Sciences, Vol 21, Iss 8, p 2717 (2020)

مصطلحات موضوعية: RX-3117, 5-aza-2′-deoxycytidine, hypomethylation, proton-coupled folate receptor, methotrexate, Biology (General), QH301-705.5, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1422-0067/21/8/2717; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067

URL الوصول: https://doaj.org/article/68b4de910bbf4c838cb3c06a99ffccf7

المؤلفون: Godefridus J. Peters, Niccola Funel, Giulia Mantini, Claudio Ricci, Elisa Giovannetti, Btissame El Hassouni, Jessica Infante

المساهمون: Medical oncology laboratory, AGEM - Re-generation and cancer of the digestive system, CCA - Imaging and biomarkers

المصدر: Anticancer Research, 39(7), 3609-3614. International Institute of Anticancer Research
Hassouni, B E L, Infante, J, Mantini, G, Ricci, C, Funel, N, Giovannetti, E & Peters, G J 2019, ' Uridine cytidine kinase 2 as a potential biomarker for treatment with RX-3117 in pancreatic cancer* ', Anticancer Research, vol. 39, no. 7, pp. 3609-3614 . https://doi.org/10.21873/anticanres.13508

مصطلحات موضوعية: Male, Cancer Research, Messenger, Antineoplastic Agents, Cytidine, Adenocarcinoma, Oncogenomics, RX-3117, Cell Line, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Pancreatic tumor, Cell Line, Tumor, Pancreatic cancer, Biomarkers, Tumor, Humans, Medicine, RNA, Messenger, Uridine cytidine kinase, Aged, Tumor, Bladder cancer, UCK2, Female, Pancreatic Neoplasms, Uridine Kinase, business.industry, Kinase, General Medicine, medicine.disease, Oncology, chemistry, 030220 oncology & carcinogenesis, Cancer research, RNA, Immunohistochemistry, Biomarker (medicine), business, Biomarkers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7f71d8abe33b2ae5690d7981a5c569e
https://doi.org/10.21873/anticanres.13508

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المؤلفون: Larry H. Matherly, Young Bok Lee, Joris R. Julsing, Dzjemma Sarkisjan, Btissame El Hassouni, Godefridus J. Peters, Deog Joong Kim, Ietje Kathmann, Richard J. Honeywell

المساهمون: Medical oncology, Medical oncology laboratory, Clinical pharmacology and pharmacy, CCA - Cancer biology and immunology, AGEM - Digestive immunity

المصدر: Sarkisjan, D, Julsing, J R, El Hassouni, B, Honeywell, R J, Kathmann, I, Matherly, L H, Lee, Y B, Kim, D J & Peters, G J 2020, ' Rx-3117 (Fluorocyclopentenyl-cytosine)-mediated down-regulation of dna methyltransferase 1 leads to protein expression of tumor-suppressor genes and increased functionality of the proton-coupled folate carrier ', International Journal of Molecular Sciences, vol. 21, no. 8, 2717 . https://doi.org/10.3390/ijms21082717
International Journal of Molecular Sciences
Volume 21
Issue 8
International Journal of Molecular Sciences, 21(8):2717. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences, Vol 21, Iss 2717, p 2717 (2020)

مصطلحات موضوعية: 0301 basic medicine, DNA (Cytosine-5-)-Methyltransferase 1, 5-aza-2′-deoxycytidine, Methyltransferase, Cytidine, DNA methyltransferase, Catalysis, Article, methotrexate, RX-3117, lcsh:Chemistry, Inorganic Chemistry, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Cell Line, Tumor, Gene expression, Humans, Physical and Theoretical Chemistry, lcsh:QH301-705.5, Molecular Biology, Spectroscopy, Dose-Response Relationship, Drug, Chemistry, Tumor Suppressor Proteins, Organic Chemistry, Promoter, General Medicine, DNA Methylation, Molecular biology, Computer Science Applications, Demethylating agent, 030104 developmental biology, lcsh:Biology (General), lcsh:QD1-999, Hypomethylating agent, Gene Expression Regulation, 030220 oncology & carcinogenesis, DNA methylation, DNMT1, Proton-Coupled Folate Transporter, hypomethylation, proton-coupled folate receptor

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a0b844558a3fc411cacfcb3190c8d10
https://research.vumc.nl/en/publications/038cd18b-dcaa-4848-94b5-1a8098b9efcb

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