المؤلفون: Rachel A. Matt, Frederick G. Westhorpe, Rosemary F. Romuar, Payal Rana, Joel R. Gever, Anthony P. Ford

المصدر: Frontiers in Molecular Biosciences, Vol 10 (2023)

مصطلحات موضوعية: adrenergic, noradrenergic, GPCR, biased agonism, agonist, desensitization, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2023.1214102/full; https://doaj.org/toc/2296-889X

URL الوصول: https://doaj.org/article/34a4c0f376f345a38da1a4da5f3b6f14

المؤلفون: Mary J. Clark, Brian K. Kobilka, Anne Stößel, Peter Gmeiner, Jake Mahoney, Jonas Kaindl, Roger K. Sunahara, Brian K. Shoichet, Xinyu Xu, Markus Stanek, Daniela Dengler, Rachel A. Matt, Harald Hübner, Magdalena Korczynska, Xiangyu Liu, Kunio Hirata

المصدر: Nature chemical biology, vol 16, iss 7
Nat Chem Biol

مصطلحات موضوعية: Protein Structure, Secondary, Biochemistry & Molecular Biology, Allosteric modulator, 1.1 Normal biological development and functioning, Adrenergic beta-Antagonists, Allosteric regulation, beta-2, Plasma protein binding, Molecular Dynamics Simulation, Ligands, Article, Protein Structure, Secondary, Norepinephrine, Medicinal and Biomolecular Chemistry, 03 medical and health sciences, Protein structure, Allosteric Regulation, Underpinning research, Receptors, Humans, Inverse agonist, Protein Interaction Domains and Motifs, Binding site, Alprenolol, Receptor, Adrenergic beta-2 Receptor Agonists, Salmeterol Xinafoate, Molecular Biology, 030304 developmental biology, Molecular switch, 0303 health sciences, Chemistry, 030302 biochemistry & molecular biology, Water, Cell Biology, Molecular Docking Simulation, Kinetics, HEK293 Cells, Adrenergic, Biophysics, Thermodynamics, Receptors, Adrenergic, beta-2, Biochemistry and Cell Biology, Allosteric Site, Protein Binding

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb6561fd608c2b2ac5658f241cc9a3e6
https://doi.org/10.1038/s41589-020-0549-2

المؤلفون: Rachel A. Matt, Daniel Hilger, Michael T. Lerch, Wayne L. Hubbell, Brian K. Kobilka, Matthieu Masureel, Matthias Elgeti, Kaavya Krishna Kumar, Bryon Foys

المصدر: Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America, vol 117, iss 50

مصطلحات موضوعية: Models, Molecular, Protein Conformation, alpha-Helical, conformational selection, Magnetic Resonance Spectroscopy, G protein, Protein Conformation, 1.1 Normal biological development and functioning, Population, beta(2) adrenergic receptor, beta-2, 03 medical and health sciences, Models, Underpinning research, Receptors, Pressure, Inverse agonist, education, Receptor, 030304 developmental biology, G protein-coupled receptor, 0303 health sciences, education.field_of_study, Multidisciplinary, Chemistry, 030302 biochemistry & molecular biology, alpha-Helical, Neurosciences, Molecular, Biological Sciences, double electron–electron resonance, β2 adrenergic receptor, basal activity, Transmembrane domain, high pressure, Förster resonance energy transfer, Membrane protein, Adrenergic, Biophysics, Thermodynamics, double electron-electron resonance, Generic health relevance, Receptors, Adrenergic, beta-2

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64a637c454c11c427136437ad06c8bd4
https://europepmc.org/articles/PMC7749303/

المؤلفون: Brian T. DeVree, Jacob P. Mahoney, Gisselle A. Vélez-Ruiz, Soren G. F. Rasmussen, Adam J. Kuszak, Elin Edwald, Juan-Jose Fung, Aashish Manglik, Matthieu Masureel, Yang Du, Rachel A. Matt, E

المصدر: Nature, Nature. 535(7610):182-186

الإتاحة: https://ideas.repec.org/a/nat/nature/v535y2016i7610d10.1038_nature18324.html

المؤلفون: Rachel A. Matt, Brian T. DeVree, Adam J. Kuszak, Els Pardon, Jan Steyaert, Aashish Manglik, Brian K. Kobilka, Jacob P. Mahoney, Elin Edwald, Matthieu Masureel, Roger K. Sunahara, Yang Du, Juan Jose Fung, Søren G. F. Rasmussen, Gisselle A. Vélez-Ruiz

المساهمون: Department of Bio-engineering Sciences, Structural Biology Brussels

المصدر: Nature, vol 535, iss 7610
Nature

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Agonist, Guanine, GTPase-activating protein, medicine.drug_class, G protein, Protein Conformation, General Science & Technology, beta-2, Biology, Ligands, Article, receptor conformation, Gs, 03 medical and health sciences, GPCR, 0302 clinical medicine, Allosteric Regulation, Models, Adrenergic beta-2 Receptor Antagonists, Heterotrimeric G protein, Receptors, GTP-Binding Protein alpha Subunits, Gs, medicine, Inverse agonist, Humans, Adrenergic beta-2 Receptor Agonists, G alpha subunit, G protein-coupled receptor, G protein-coupled receptor kinase, Multidisciplinary, Neurosciences, Molecular, GTP-Binding Protein alpha Subunits, Kinetics, 030104 developmental biology, Biochemistry, Adrenergic, nucleotide-free, Biophysics, Generic health relevance, Receptors, Adrenergic, beta-2, 030217 neurology & neurosurgery, Allosteric Site, Protein Binding, Single-Chain Antibodies

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63b9eed8cbafd00ee985f7f86f93d80f
https://escholarship.org/uc/item/2h8808kk

المؤلفون: William I. Weis, Rachel A. Matt, Brian K. Kobilka, Thor S. Thorsen

المصدر: Structure (London, England : 1993). 22(11)

مصطلحات موضوعية: Models, Molecular, Muscarinic acetylcholine receptor M3, Crystal structure, Biology, Crystallography, X-Ray, Fusion protein, Article, Receptors, G-Protein-Coupled, chemistry.chemical_compound, Viral Proteins, chemistry, Biochemistry, Membrane protein, Structural Biology, Biophysics, Bacteriophage T4, Muramidase, Lysozyme, Receptor, Crystallization, Molecular Biology, Intracellular, G protein-coupled receptor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61ae5b9739747c7dce84596fb68eade0
https://pubmed.ncbi.nlm.nih.gov/25450769

المؤلفون: Nicholas Cecil; Daniel O'Mahony; Rachel Dickerson; Matt Watts

المصدر: Evening Standard; 6/26/2017, p6, 2p

المؤلفون: Rachel Millard; Matt Oliver

المصدر: Daily Mail; 6/5/2018, p20, 1p

المؤلفون: Rachel Millard ; Matt Oliver

المصدر: Daily Mail; 6/5/2018, p20, 1p

المؤلفون: Rachel Millard; Matt Oliver

المصدر: Daily Mail; 3/19/2018, p8, 1p