المؤلفون: Levi J. Rupp, Kathrin Schumann, Kole T. Roybal, Rachel E. Gate, Chun J. Ye, Wendell A. Lim, Alexander Marson

المصدر: Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/665f79f789f343fe9fc1e3bc666749d5

المؤلفون: David Mavor, Kyle Barlow, Samuel Thompson, Benjamin A Barad, Alain R Bonny, Clinton L Cario, Garrett Gaskins, Zairan Liu, Laura Deming, Seth D Axen, Elena Caceres, Weilin Chen, Adolfo Cuesta, Rachel E Gate, Evan M Green, Kaitlin R Hulce, Weiyue Ji, Lillian R Kenner, Bruk Mensa, Leanna S Morinishi, Steven M Moss, Marco Mravic, Ryan K Muir, Stefan Niekamp, Chimno I Nnadi, Eugene Palovcak, Erin M Poss, Tyler D Ross, Eugenia C Salcedo, Stephanie K See, Meena Subramaniam, Allison W Wong, Jennifer Li, Kurt S Thorn, Shane Ó Conchúir, Benjamin P Roscoe, Eric D Chow, Joseph L DeRisi, Tanja Kortemme, Daniel N Bolon, James S Fraser

المصدر: eLife, Vol 5 (2016)

مصطلحات موضوعية: deep mutational scanning, ubiquitin, proteostasis, chemical biology, proteasome, biophysics, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/15802; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/f3e8373dbc7b4012a1c82425c9fb49fb

المؤلفون: Jonathan M. Woo, Sasha Targ, Kathrin Schumann, Matthew H. Spitzer, Michelle L.T. Nguyen, Alexander Marson, Chun Jimmie Ye, Theodore L. Roth, Nikolaos Skartsis, Michael Lauber, Ruby Yu, Qizhi Tang, David N. Nguyen, Jeffrey A. Bluestone, Saskia Kolb, Eric Shifrut, Siddharth S. Raju, Jessica T. Cortez, Rachel E. Gate, Vinh Son Nguyen, Dimitre R. Simeonov

المصدر: Nature immunology, vol 21, iss 11
Nature immunology

مصطلحات موضوعية: 0301 basic medicine, Regulatory T cell, T-Lymphocytes, 1.1 Normal biological development and functioning, Immunology, Gene regulatory network, Graft vs Host Disease, chemical and pharmacologic phenomena, Biology, T-Lymphocytes, Regulatory, Article, Vaccine Related, 03 medical and health sciences, Gene Knockout Techniques, 0302 clinical medicine, Underpinning research, PRDM1, medicine, Genetics, Immunology and Allergy, CRISPR, Humans, 2.1 Biological and endogenous factors, Gene Regulatory Networks, Clustered Regularly Interspaced Short Palindromic Repeats, Aetiology, Regulation of gene expression, Gene Expression Profiling, Inflammatory and immune system, Gene targeting, FOXP3, High-Throughput Nucleotide Sequencing, hemic and immune systems, Regulatory, Cell biology, Gene expression profiling, 030104 developmental biology, medicine.anatomical_structure, Gene Expression Regulation, Gene Targeting, Immunization, Disease Susceptibility, Generic health relevance, CRISPR-Cas Systems, Transcriptome, Biomarkers, 030215 immunology, Biotechnology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7505bee01708a1d10ef7deae33334923
https://escholarship.org/uc/item/06z4n1xt

المؤلفون: Lindsey A. Criswell, Michelle L.T. Nguyen, Noah Zaitlen, Cristina Lanata, Rachel E. Gate, Sasha Targ, Lauren Byrnes, Elizabeth E. McCarthy, Alexander Marson, Hyun Min Kang, Eunice Wan, Meena Subramaniam, Lenka Maliskova, Simon Wong, Sara Mostafavi, Chun Jimmie Ye

المصدر: Nature biotechnology

مصطلحات موضوعية: 0301 basic medicine, Genotype, Quantitative Trait Loci, Cell, Biomedical Engineering, Bioengineering, Single-nucleotide polymorphism, Computational biology, Biology, Polymorphism, Single Nucleotide, Applied Microbiology and Biotechnology, Article, Transcriptome, 03 medical and health sciences, Genetic variation, medicine, Humans, Lupus Erythematosus, Systemic, Genotyping, High-Throughput Nucleotide Sequencing, RNA, 030104 developmental biology, medicine.anatomical_structure, Expression quantitative trait loci, Molecular Medicine, Interferons, Single-Cell Analysis, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9f80c24248482b685a6ba752cd7c20b
http://europepmc.org/articles/PMC5784859

المؤلفون: Wendell A. Lim, Kole T. Roybal, Alexander Marson, Rachel E. Gate, Kathrin Schumann, Levi J. Rupp, Chun Jimmie Ye

المصدر: Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports
Scientific reports, vol 7, iss 1
Rupp, LJ; Schumann, K; Roybal, KT; Gate, RE; Ye, CJ; Lim, WA; et al.(2017). CRISPR/Cas9-mediated PD-1 disruption enhances anti-tumor efficacy of human chimeric antigen receptor T cells. SCIENTIFIC REPORTS, 7. doi: 10.1038/s41598-017-00462-8. UCSF: Retrieved from: http://www.escholarship.org/uc/item/6ds29844

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, T-Lymphocytes, Cell, Programmed Cell Death 1 Receptor, Gene Expression, B7-H1 Antigen, Mice, Immunophenotyping, Cancer immunotherapy, Neoplasms, Receptors, Cytotoxic T cell, IL-2 receptor, Cancer, Mice, Knockout, Multidisciplinary, Tumor, CD19, Gene Therapy, 3. Good health, Other Physical Sciences, medicine.anatomical_structure, Antigen, Gene Knockdown Techniques, Gene Targeting, Medicine, Female, Development of treatments and therapeutic interventions, Biotechnology, Knockout, Science, Antigens, CD19, Receptors, Antigen, T-Cell, Biology, Article, Cell Line, 03 medical and health sciences, Clinical Research, Antigens, Neoplasm, Cell Line, Tumor, medicine, Genetics, Animals, Humans, Antigens, 5.2 Cellular and gene therapies, T-Cell, Molecular biology, Chimeric antigen receptor, 030104 developmental biology, Good Health and Well Being, Cell culture, Cancer research, Neoplasm, Immunization, Biochemistry and Cell Biology, CRISPR-Cas Systems, Biomarkers

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1547b70458f27be1e6201caffafa4294
https://doaj.org/article/665f79f789f343fe9fc1e3bc666749d5

المؤلفون: Richard M. Locksley, Joshua L. Pollack, Hong-Erh Liang, Steven J. Van Dyken, Rachel E. Gate, Jinwoo Lee, Chun Jimmie Ye, Jesse C. Nussbaum, Ari B. Molofsky, David J. Erle, Genevieve E. Haliburton, Alexander Marson

المصدر: Nature Immunology. 17:1381-1387

مصطلحات موضوعية: 0301 basic medicine, Thymic stromal lymphopoietin, Immunology, Priming (immunology), Inflammation, Adaptive Immunity, Biology, Allergic inflammation, Mice, 03 medical and health sciences, Th2 Cells, Thymic Stromal Lymphopoietin, Interleukin 25, Hypersensitivity, medicine, Animals, Immunology and Allergy, Lymphocytes, Cells, Cultured, Mice, Knockout, Mice, Inbred BALB C, Dermatophagoides farinae, Effector, Interleukin-17, Innate lymphoid cell, Cell Differentiation, Allergens, Bees, Interleukin-33, Acquired immune system, Immunity, Innate, Mice, Inbred C57BL, Bee Venoms, 030104 developmental biology, Cytokines, Aspergillus niger, medicine.symptom

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd5b0387d54b84ddf30f1ea037d37fd7
https://doi.org/10.1038/ni.3582

المؤلفون: Hyun Min Kang, Meena Subramaniam, Sasha Targ, Michelle Nguyen, Lenka Maliskova, Elizabeth McCarthy, Eunice Wan, Simon Wong, Lauren Byrnes, Cristina M Lanata, Rachel E Gate, Sara Mostafavi, Alexander Marson, Noah Zaitlen, Lindsey A Criswell, Chun Jimmie Ye

مصطلحات موضوعية: Computer science, Genome informatics, Computational biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::004e2bf4aa664802cf4c7953a924c13d
https://doi.org/10.17504/protocols.io.233ggqn

المؤلفون: Sean Simmons, Michelle Lee, Raktima Raychowdhury, Barbara E. Stranger, Irene Y. Frohlich, Mark Lee, Nir Hacohen, Selina Imboywa, Alexandra-Chloé Villani, Noga Rogel, Meena Subramaniam, Philip L. De Jager, Portia Chipendo, Weibo Li, Rachel E. Gate, Timothy W. Behrens, Aviv Regev, Jenny Chen, Chun Jimmie Ye, Towfique Raj, Cristin McCabe, Tushar Bhangale

المصدر: Genome research, vol 28, iss 12

مصطلحات موضوعية: Untranslated region, 0301 basic medicine, Male, Balancing selection, Aminopeptidases, Medical and Health Sciences, Monocytes, Models, 2.1 Biological and endogenous factors, Aetiology, Genetics (clinical), Genetics, Regulation of gene expression, Chromosome Mapping, Middle Aged, Biological Sciences, Infectious Diseases, Influenza A virus, Interferon Type I, Host-Pathogen Interactions, Pneumonia & Influenza, Female, Infection, Human, Biotechnology, Gene isoform, Adult, Adolescent, Bioinformatics, Quantitative Trait Loci, Genomics, Single-nucleotide polymorphism, Locus (genetics), Quantitative trait locus, Biology, Models, Biological, 03 medical and health sciences, Young Adult, Influenza, Human, Humans, Genetic Predisposition to Disease, Genetic Testing, Gene, Research, Gene Expression Profiling, Haplotype, Human Genome, Computational Biology, Genetic Variation, Molecular Sequence Annotation, Dendritic Cells, Biological, Influenza, Gene expression profiling, Alternative Splicing, 030104 developmental biology, Gene Ontology, Gene Expression Regulation, Transcriptome

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d4ab31439692e4ce3e29539cbc06050
https://escholarship.org/uc/item/8fz4z7mw

المؤلفون: Elizabeth E. McCarthy, Cristina Lanata, Michelle L.T. Nguyen, Lenka Maliskova, Lindsey A. Criswell, Meena Subramaniam, Simon Wong, Noah Zaitlen, Lauren Byrnes, Rachel E. Gate, Sasha Targ, Chun Jimmie Ye, Sara Mostafavi, Eunice Wan, Alexander Marson, Hyun Min Kang

المصدر: Nature Biotechnology. 38:1356-1356

مصطلحات موضوعية: medicine.anatomical_structure, Genetic variation, Cell, Biomedical Engineering, medicine, Molecular Medicine, RNA, Bioengineering, Computational biology, Biology, Applied Microbiology and Biotechnology, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d41dec36e7ee62123b9ba50070689b9e
https://doi.org/10.1038/s41587-020-0715-9

المؤلفون: M. Grace Gordon, Michael A. Beer, Kendrick L Hougen, Atsede Siba, Christine S. Cheng, Erez Lieberman Aiden, Aviv Regev, Christophe Benoist, Marcin Tabaka, Aviva Presser Aiden, Muhammad S. Shamim, Dmytro Lituiev, Meena Subramaniam, Su-Chen Huang, Han Chang, Chun J Ye, Philip L. De Jager, Ido Machol, Ting Feng, Rachel E. Gate, Neva C. Durand, Ivo Wortman

المساهمون: Massachusetts Institute of Technology. Department of Biology, Koch Institute for Integrative Cancer Research at MIT

المصدر: Nature genetics, vol 50, iss 8
PMC
Nature genetics

مصطلحات موضوعية: 0301 basic medicine, CD4-Positive T-Lymphocytes, Adult, Male, Genotype, Regulatory Sequences, Nucleic Acid, Biology, Polymorphism, Single Nucleotide, Medical and Health Sciences, Article, Autoimmune Diseases, 03 medical and health sciences, Clinical Research, Polymorphism (computer science), Gene expression, Genetics, 2.1 Biological and endogenous factors, Humans, Epigenetics, Aetiology, Polymorphism, Regulation of gene expression, Nucleic Acid, Human Genome, Single Nucleotide, Biological Sciences, Stem Cell Research, Chromatin, 3. Good health, 030104 developmental biology, Gene Expression Regulation, Regulatory sequence, Female, Functional genomics, Regulatory Sequences, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d963e9167b7acfbb5fd3605855d1044
https://escholarship.org/uc/item/8762v2z6