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المؤلفون: Barbara A. Gregson, Rachel L. Lakey, Ganesh Subramanian, Anand Dixit, Philip White, Robert Simister, Elena A. Cora, Ahmed Maiter, Gary A. Ford, Yogish Joshi
المصدر: Journal of NeuroInterventional Surgery. 13:311-318
مصطلحات موضوعية: Male, medicine.medical_specialty, Randomization, medicine.medical_treatment, Population, Brain Ischemia, law.invention, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, law, Humans, Medicine, Single-Blind Method, Thrombolytic Therapy, Prospective Studies, Treatment Failure, 030212 general & internal medicine, Infusions, Intravenous, education, Stroke, Aged, Thrombectomy, Aged, 80 and over, education.field_of_study, Intention-to-treat analysis, business.industry, Cerebral infarction, General Medicine, Thrombolysis, Middle Aged, medicine.disease, Surgery, Catheter, Treatment Outcome, Female, Neurology (clinical), business, 030217 neurology & neurosurgery
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المؤلفون: Louise Sutcliffe, Helen Snooks, Gary A. Ford, Saiful Islam, Richard Francis, Alan Watkins, Joanne Lally, Peter McMeekin, Helen Rodgers, Graham McClelland, Lisa Shaw, Rachel L. Lakey, Christopher Price, Darren Flynn, Ian Russell, Luke Vale, Catherine Exley, Mehdi Javanbakht
المصدر: International Journal of Stroke. 14:9-55
مصطلحات موضوعية: medicine.medical_specialty, Neurology, business.industry, Treatment assessment, Emergency medicine, Medicine, business, medicine.disease, Stroke, Acute stroke
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3b369a8d46ce66ac5610f13c81f596ad
https://doi.org/10.1177/1747493019882907 -
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المؤلفون: Richard Francis, Joanne Lally, Luke Vale, Christopher Price, Graham McClelland, Alan Watkins, Saiful Islam, Louise Sutcliffe, Rachel L. Lakey, Catherine Exley, Helen Snooks, Gary A. Ford, Lisa Shaw, Darren Flynn, Mehdi Javanbakht, Ian Russell, Peter McMeekin, Helen Rodgers
المصدر: JAMA neurology. 77(7)
مصطلحات موضوعية: Male, medicine.medical_specialty, Emergency Medical Services, Randomization, medicine.medical_treatment, Psychological intervention, law.invention, Time-to-Treatment, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, law, medicine, Emergency medical services, Humans, Thrombolytic Therapy, 030212 general & internal medicine, Stroke, Aged, Ischemic Stroke, Aged, 80 and over, business.industry, Thrombolysis, Middle Aged, medicine.disease, Checklist, Emergency Medical Technicians, Treatment Outcome, Emergency medicine, Female, Neurology (clinical), business, 030217 neurology & neurosurgery, Prehospital Emergency Care
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::189f1569635d0b147f7b439408224edc
https://pubmed.ncbi.nlm.nih.gov/32282015 -
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المؤلفون: Alan Watkins, Lisa Shaw, Darren Flynn, Saiful Islam, Catherine Exley, Graham McClelland, Luke Vale, Joanne Lally, Louise Sutcliffe, Christopher Price, Mehdi Javanbakht, Peter J. Dodd, Rachel L. Lakey, Pippa Tyrell, Helen Rodgers, Peter McMeekin, Richard Francis, Helen Snooks, Gary A. Ford
المصدر: Trials
Trials, Vol 20, Iss 1, Pp 1-18 (2019)مصطلحات موضوعية: Adult, medicine.medical_specialty, Emergency Medical Services, Quality Assurance, Health Care, medicine.medical_treatment, Cost-Benefit Analysis, Allied Health Personnel, Medicine (miscellaneous), B200, Paramedics, Disease cluster, law.invention, 03 medical and health sciences, Study Protocol, 0302 clinical medicine, Randomized controlled trial, law, medicine, Humans, Pharmacology (medical), Thrombolytic Therapy, 030212 general & internal medicine, Parallel process evaluation, Stroke, Randomized Controlled Trials as Topic, Protocol (science), lcsh:R5-920, business.industry, Thrombolysis, A300, medicine.disease, Economic evaluation, Clinical trial, Pre-hospital research, Sample size determination, Sample Size, Emergency medicine, Health Resources, lcsh:Medicine (General), business, 030217 neurology & neurosurgery, RCT
وصف الملف: application/pdf
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المؤلفون: Ruth Graham, Charlotte Eglinton, Swapna Kunhunny, J Banns, Alison K Wright, Sunil Munshi, C Khuoge, Beverley McClelland, A Benford, Jean Buxton, Maia Beridze, K Deighton, Neha Chopra, Nichola Motherwell, Emily C. O'Brien, Sonia S. Anand, Anand Dixit, Una Poultney, N Beridze, Jessica Beavan, K Dizayee, Thompson G. Robinson, Deborah Howcroft, Alison Sarah rachel Mcloughlin, A Kenton, Derek Esson, A Tittle, L Matter, Kerstin Knops, C Hubbuck, Kath Chapman, R Rangasamay, Ranjan Sanyal, Sarah Lewis, Alpha Anthony, Sarah Board, Janice Irvine, Anna Verrion, Katherine Whittamore, N Khizanishvili, L O'Shea, Lisa Shaw, K Ayes, Tracey Dobson, N Akiashvili, Gill Rogers, Jenny Peters, Alda Remegoso, S S Hansen, James A. White, T Attygalle, Rosalind Brown, Irene Martin, Manesh R. Patel, D O'Kane, Stuart J. Pocock, Khalid Rashed, G Spurling, Sharon Tysoe, Frances Harrington, Margo Henry, Rowilson Jarapa, Julia Hindle, K A Kay, Carinna Vickers, S Duty, Angela Bowring, David Eveson, Saul Sundayi, Mary Kambafwile, Rashmi Kumar, Jack Roffe, Marilyn James, Natalie Temple, R Oliver, Christine Kelly, M Niemierko, J Chembala, S Jones, M Dent, K Chatterjee, S Atkinson, J Tomlinson, S Norman, E Cattermole, P Daboo, Nicola Gilzeane, Anne Hardwick, Pietro Cariga, C Rankin, David A. Wood, Lelia Duley, John Bamford, L Holford, J Good, C Ambulo, S Gomm, Girish Muddegowda, Fiona Wright, M Alao, L Sztriha, Maite D. Rodriguez, Christine Dickson, S Merotra, Helen Bearne, Ann Needle, Emma Mckenzie, Olga Balazikova, Emily Osborne, A Lankester, Rod S Taylor, Pauline Fitzell, Bernard Esisi, E Young, Richard Donnelly, Anu Joyson, Debbie Morgan, Fran Watson, Caroline Mcinnes, C Padilla-Harris, Stephanie McCann, T Ajao, Suzanne Lucas, Inez Wynter, Barbara Longland, Don Sims, Gavin Bateman, Anthony Hemsley, Vera Cvoro, Fiona Kennedy, Peter Langhorne, Adrian Butler, P Jacob, Barry Moynihan, Amit K. Mistri, W Sunman, Hannah Beadle, Polly Scutt, M Garside, Glyn Fletcher, Deborah Walstow, L Ryan, Michelle Fawcett, D Wilkinson, E Gibson, O Orugun, Malcolm R. Macleod, Philip M.W. Bath, Elio Giallombardo, T Kherkheulidze, Lourda Kerin, Clare Doyle, Brigid Hairsine, N Kakabadze, B Wadams, Enas Lawrence, Dinesh Chadha, I Memon, Cheryl L. Perkins, Victoria Sutton, C.B. Patel, A Ravindrane, K Javaid, Mahmud Sajid, T Tsanava, Y Duodu, Timothy J. England, Geoffrey A. Rose, Sheila Nyabadza, Louisa M. Christensen, M Bajoriene, F Faola, J Kok, C Vernon, Aravindakshan Manoj, E Horsley, T Gordon, Linda Cowie, S Hurdowar, D Sandler, Temi Adedoyin, Mandy Couser, C Jenkins, C Pringle, Paula Lopez, Vicky Taylor, James Cunningham, Gillian Courtauld, S Maheswaran, H Rehman, Christine Roffe, M Sein, Carla Richardson, John B. Davis, Nenette Abano, Racquel Carpio, Sheila Mashate, P Christian, Lynn Dixon, Dulka Manawadu, Jeanette Grocott, Peter Owusu-Agyei, P Farren, F K Chan, Komal Ali, Annemarei Ranta, Judith Clarke, Dean Waugh, Stan Heptinstall, M Reader, Nikola Sprigg, John F. Corrigan, Caroline Roughan, F Brodie, Paula Harman, P Webster, Kenneth Smith, Julie Reddan, Angela Willberry, Peter Howard, Kay Finney, S Buddha, C Hewitt, M Zaidi, Tracy Marsden, Heather Gow, Robert A. Dineen, Kimberley Netherton, Kashif Musarrat, Emma Barbon, V Riddell, G Storey, Ahamad Hassan, O Adegbaju, S Wong, Bethan Charles, Bindu Gregary, Rhys Williams, M G Metiu, Nilofer Dayal, C Lawlor, Kirsten E Anderson, R Icart Palau, N Khanom, C Stevenson, Prabel Datta, Betty Mokoena, Kelly Chan, Amanda Hedstrom, Sonia Raj, Y Gruenbeck, D Dellafera, Georgina Butt, A Peacocke, James Okwera, L Mokoena, Holly Maguire, Mohana Maddula, C Bailey, Ian Shread, LáShauntá M. Glover, Elizabeth Keeling, Mari Smith, Jane Powell, A Tevdoradze, Christopher Price, Hannah Rudenko, K Gill, Laura Howaniec, P Lingwood, Katherine Marks, Ivan Iniesta, F Barrett, Barbara Madigan, Emery N. Brown, Katie Flaherty, Gail Hann, Mark Barber, Kelley Storey, Aparna Pusalkar, Jason P. Appleton, Joanne Hiden, R Jolly, Hedley C. A. Emsley, J Chambers, Christina Kruuse, Mairead Osborn, P Lai, Tracy Fuller, David G. Bruce, Robert Namushi, Martin Cooper, Peter Murphy, Naomi Jeyaraj, Hayley Kingwell, A Nair, Robert S.M. Davies, Katrina McCormick, Rachel L. Lakey, Sharon Dealing, F Leslie, Peter Wilkinson, Amitava Banerjee, Penelope Cox, Janice E. O’Connell, N Sikondari, Sandra Leason, Lisa J Woodhouse, Judith Bell, Puneet Dangri, Donna Butler, Judith Dube, Rachel Gascoyne, Amberly Brigden, Debs Kelly, Renuka Erande, Kirsty Harkness, Sarah Trippier, Kirsten Harvey, Georgina Ayres, R Rowland-Axe, E Campbell, Sue Lyjko, Sylvia Szabo, David Mangion, Suzanne Ragab, C Hilaire, Alan A Montgomery, Dawn Tomlin, John Paterson, K Muhidden, Grace Auld, C Keaveney, Hannah Crowther, Lisa Hyatt, Louise E. Jackson, K Castro, Khaled Elfandi, H Russell, S Tennant, Ozlem Redjep, Tim Cassidy, Linda Y Johnson, Amulya Misra, E Khoromana, Catherine Ovington, Stuart Maguire, S Khan, Zoe Mellor, Michael Funnell, Hugh S. Markus, Emma Richards, I Toidze, Colin Smith, R Sivakumar, Janet Wilson, Amina Ahmed, A Mohd Nor, A Barkat, Line Bentsen, K Whysall, Carol L Clarke, N Sengupta, Meena Srinivasan, Balakrishna Kumar, Mgg Soliman, A Thomson, Adrian Barry, Abul Azim, Ed Gamble, H Eccleson, Kelly Marie Shaw, Christine Schofield, Linetty Makawa, Carole Hays, David Hargroves, Jordi Margalef, S Butler, H Webb, Carol Denniss, Samantha Stafford, Faye Shelton, D Forrest, Amanda Buck, Tarn Nozedar, Indira Natarajan, Jane Perez, Susanna R. Stevens, Denise Button, Mary Johnes, Samantha Keenan, Olivia C. Geraghty, Eva Beranova, Emma Jinks, S Hassan, Caroline McGhee, Nicola Persad, Gunaratnam Gunathilagan, Clare Buckley, Jennifer Mitchell, Mike Clarke, Mathew Burn, B Bhaskaran, D Hayward, Lucy Belle Guthrie, S Meenakshisundaram, Anushka Warusevitane, O Speirs, J O'Callaghan, Sudipto Ghosh, Peter Wilding, Helen Cochrane, Susan Clayton, Mandy Doherty, Fiona Price, L Montague, Valerie Hogg, S Arif, Beth Hazel, Margaret Ball, S Johnson-Holland, S Booth, N Rands, Dionne Hove, Teresa Thompson, C Krarup Hansen, Lisa Manning, Andrew Smith, Jo Howe, Jill Greig, Kailash Krishnan, Caroline Watchurst, L Finlay, Sandra Nelson, Toby Black, S Tilby, Zin Naing, D Morse, David Broughton, K Preece, M Platton, M Siddiqui, Angela Dodd, Catrin Blank, Maria Bokhari, Jacqueline Furnace, F Hammonds, Helen Guy, A Lehman, J Hunt, S Windebank, Becky Jupp, K Fotherby, Ruth Bellfield, P Wanklyn, D Hilton, Amy Steele, S Mahmood, N Lobjanidze, Sarah Finlay, L Hunt, M Krasinska-Chavez, Gemma Grimwood, H H Jensen, J. Duignan, Jane Gaylard, Asaipillai Asokanathan, Joanna O'Reilly, J Kessell, Diane Havard, T Fluskey, L Lee-Carbon, Graham Venables, Margi Godfrey, L Boxall, C Douglass, Emelda Veraque, Elaine Amis, M Chowdhury, Rekha Keshvara, Adrian Blight, G Thomas, Marc Randall, S Stoddart, Paul Guyler, Rita Ghatala, Janet T Scott, Kathy J. Jenkins, Sarah Ross, John Aeron-Thomas, C Allcock, J Goodsell, Ifan Jones, D Kakabadze, T T Thomsen, V Petrovic, I. Watson, C Athulathmudali, Hanne Christensen, Susan Crawford, Christine Kamara, James McIlmoyle, Stephen Woodward, Christine McAlpine, Emma Temlett, Gwendoline Wilkes, Benjamin Hyams, L Mills, S Brixey, Raj Shekhar, P Findlay
المساهمون: Markus, Hugh [0000-0002-9794-5996], Apollo - University of Cambridge Repository
مصطلحات موضوعية: Male, medicine.medical_specialty, Georgia, Ticlopidine, Denmark, Hemorrhage, 030204 cardiovascular system & hematology, Risk Assessment, Brain Ischemia, 03 medical and health sciences, 0302 clinical medicine, Ischemia, Recurrence, Modified Rankin Scale, Internal medicine, medicine, Humans, Thrombolytic Therapy, Prospective Studies, cardiovascular diseases, Stroke, Aged, Aspirin, business.industry, Dipyridamole, General Medicine, Guideline, Middle Aged, Clopidogrel, medicine.disease, United Kingdom, Treatment Outcome, Ischemic Attack, Transient, Research Design, Acute Disease, Platelet aggregation inhibitor, Drug Therapy, Combination, Female, business, Platelet Aggregation Inhibitors, 030217 neurology & neurosurgery, New Zealand, medicine.drug
وصف الملف: application/pdf; PDF
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المؤلفون: Tim E. Cawston, Rachel L. Lakey
المصدر: Rheumatology. 48:1208-1212
مصطلحات موضوعية: Cartilage, Articular, medicine.medical_specialty, Drug Evaluation, Preclinical, Down-Regulation, Oncostatin M, Matrix metalloproteinase, Gene Expression Regulation, Enzymologic, Nasal Cartilages, Rheumatology, Interleukin-1alpha, Internal medicine, medicine, Animals, Humans, Pharmacology (medical), Cells, Cultured, Dose-Response Relationship, Drug, biology, business.industry, ADAMTS, Cartilage, Anti-Inflammatory Agents, Non-Steroidal, Osteoarthritis, Knee, Bovine Cartilage, Cell biology, Sulfasalazine, Hyaline Cartilage, medicine.anatomical_structure, Endocrinology, Proteoglycan, Antirheumatic Agents, Culture Media, Conditioned, Metalloproteases, Collagenase, biology.protein, Interstitial collagenase, Cattle, Proteoglycans, Collagen, business, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d206bfceadeee16edfdd639e1c214f8d
https://doi.org/10.1093/rheumatology/kep236 -
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المؤلفون: Rachel L. Lakey, Andrew D. Rowan, John D. Isaacs, Catharien M. U. Hilkens, Tanya G. Morgan, Tim E. Cawston
المصدر: Rheumatology. 48:502-507
مصطلحات موضوعية: Cartilage, Articular, Immunoglobulin gamma-Chains, Recombinant Fusion Proteins, CD40 Ligand, Receptors, Tumor Necrosis Factor, Arthritis, Rheumatoid, Pathogenesis, Rheumatology, Downregulation and upregulation, medicine, Humans, Pharmacology (medical), Collagenases, Receptor, Cells, Cultured, CD40, biology, Tumor Necrosis Factor-alpha, business.industry, Cartilage, Antibodies, Monoclonal, Dendritic Cells, Dendritic cell, Coculture Techniques, Infliximab, Up-Regulation, Cell biology, medicine.anatomical_structure, Immunology, biology.protein, Collagenase, Tumor necrosis factor alpha, Collagen, business, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2319591c214cd768ed3732e4a2fedb5
https://doi.org/10.1093/rheumatology/kep040 -
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المؤلفون: Mark A. Birch, Kenneth S. Rankin, Craig Gerrand, Andrew McCaskie, Andrew P. Sprowson, Rachel L. Lakey
المصدر: Calcified Tissue International. 83:1-33
مصطلحات موضوعية: Endocrinology, Chemistry, Endocrinology, Diabetes and Metabolism, medicine, Cancer research, Orthopedics and Sports Medicine, Breast cancer cells, Hypoxia (medical), medicine.symptom, Matrix metalloproteinase
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المؤلفون: Timothy Robson, Tim E. Cawston, Rachel L. Lakey, D Jones, Gary J. Litherland, Craig Dixon, Andrew D. Rowan, David Young
المصدر: Journal of Biological Chemistry. 283:14221-14229
مصطلحات موضوعية: AKT1, Oncostatin M, Protein Serine-Threonine Kinases, Matrix metalloproteinase, Biochemistry, Gene Expression Regulation, Enzymologic, Extracellular matrix, Mice, Phosphatidylinositol 3-Kinases, chemistry.chemical_compound, Chondrocytes, Animals, Humans, Collagenases, Phosphatidylinositol, Phosphorylation, Protein Kinase Inhibitors, Molecular Biology, Protein kinase B, Cells, Cultured, PI3K/AKT/mTOR pathway, biology, Interleukin-6, Chemistry, Pyruvate Dehydrogenase Acetyl-Transferring Kinase, Cell Biology, Cell biology, Isoenzymes, Cartilage, Immunology, biology.protein, Signal transduction, Proto-Oncogene Proteins c-akt, Interleukin-1, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d9525dcf913bbefbfb93b28dcb6e9f0
https://doi.org/10.1074/jbc.m710136200 -
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المؤلفون: Tim E. Cawston, Lesley Kay, Rachel L. Lakey, David Walker, A Myers
المصدر: Rheumatology. 43:272-276
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Spondyloarthropathy, Arthritis, Late onset, Gastroenterology, Psoriatic arthritis, Rheumatology, Psoriasis, Internal medicine, medicine, Humans, Pharmacology (medical), Age of Onset, Tissue Inhibitor of Metalloproteinase-1, business.industry, Siblings, Arthritis, Psoriatic, Middle Aged, medicine.disease, Case-Control Studies, Rheumatoid arthritis, Immunology, Female, Matrix Metalloproteinase 1, Age of onset, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::995a424add85a491f97ee210bc318c62
https://doi.org/10.1093/rheumatology/keh032