نتائج البحث - "Raffaella, Grimaldi"

المساهمون: Roberto Dante Cogliandro, Roberto, Dante Cogliandro, Filomena, Chirulli, Esmeralda, Addabbo, Mario, Squadroni, Adele, Maria Delle Fave, Marina Di, Marco, Raffaella, Grimaldi, Dalli, Gian Pietro, Ferretti, Alessandro, Ricci, Silvia, Andrea, Fantin, Alessandro, Zanmarchi, Burbarelli, Gabriele, Lodovico, Genghini, Emanuela Esposito, Orlando, Chiara, Magneschi, Giuseppe, Averardi, Angelo, Rosario Sciotto, Michela, Bigonzoni, Fabiana, Pirone

مصطلحات موضوعية: beni pubblici - enti pubblici - beni culturali - circolazione - prelazione

وصف الملف: STAMPA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______4094::e7d83005e7a2fc63ecf2a937235d97e0
http://hdl.handle.net/11585/583278

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From On-Target to Off-Target Activity: Identification and Optimisation ofTrypanosoma bruceiGSK3 Inhibitors and Their Characterisation as Anti-Trypanosoma bruceiDrug Discovery Lead Molecules

المؤلفون: Andrew Woodland, Torsten Luksch, Julie A. Frearson, Kayode K. Ojo, Paul G. Wyatt, Ian H. Gilbert, Ruth Brenk, Laura A. T. Cleghorn, Wesley C. Van Voorhis, Raffaella Grimaldi

المصدر: Chemmedchem

مصطلحات موضوعية: Models, Molecular, Trypanosoma brucei brucei, Biology, Trypanosoma brucei, Biochemistry, GSK3, Cell Line, Glycogen Synthase Kinase 3, Structure-Activity Relationship, 03 medical and health sciences, Parasitic Sensitivity Tests, medicinal chemistry, parasitic diseases, Drug Discovery, medicine, Humans, Structure–activity relationship, African trypanosomiasis, General Pharmacology, Toxicology and Pharmaceutics, Protein kinase A, Protein Kinase Inhibitors, Cell Proliferation, 030304 developmental biology, Pharmacology, protein kinases, 0303 health sciences, Dose-Response Relationship, Drug, Molecular Structure, 030306 microbiology, Drug discovery, Kinase, Organic Chemistry, Full Papers, medicine.disease, biology.organism_classification, Trypanocidal Agents, In vitro, 3. Good health, Molecular Medicine, Pharmacophore, antiprotozoal agents

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e7d53b1adcfccbe87e8c471bd2b0e51
https://doi.org/10.1002/cmdc.201300072

View record at Wiley

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Discovery of Inhibitors of Trypanosoma brucei by Phenotypic Screening of a Focused Protein Kinase Library

المؤلفون: Andrew, Woodland, Stephen, Thompson, Laura A T, Cleghorn, Neil, Norcross, Manu, De Rycker, Raffaella, Grimaldi, Irene, Hallyburton, Bhavya, Rao, Suzanne, Norval, Laste, Stojanovski, Reto, Brun, Marcel, Kaiser, Julie A, Frearson, David W, Gray, Paul G, Wyatt, Kevin D, Read, Ian H, Gilbert

المصدر: Chemmedchem

مصطلحات موضوعية: Trypanosoma brucei rhodesiense, Dose-Response Relationship, Drug, Molecular Structure, Full Papers, Cell Line, Small Molecule Libraries, Structure-Activity Relationship, Phenotype, cidal, kinases, static, Parasitic Sensitivity Tests, phenotypic, Drug Discovery, Humans, Trypanosoma brucei, Protein Kinase Inhibitors, Protein Kinases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::757e4bb5ea957f8530d9741d8367b6c7
https://pubmed.ncbi.nlm.nih.gov/26381210

View record at Wiley

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A novel multiple-stage antimalarial agent that inhibits protein synthesis

المؤلفون: Beatriz, Baragaña, Irene, Hallyburton, Marcus C S, Lee, Neil R, Norcross, Raffaella, Grimaldi, Thomas D, Otto, William R, Proto, Andrew M, Blagborough, Stephan, Meister, Grennady, Wirjanata, Andrea, Ruecker, Leanna M, Upton, Tara S, Abraham, Mariana J, Almeida, Anupam, Pradhan, Achim, Porzelle, Torsten, Luksch, María Santos, Martínez, Judith M, Bolscher, Andrew, Woodland, Suzanne, Norval, Fabio, Zuccotto, John, Thomas, Frederick, Simeons, Laste, Stojanovski, Maria, Osuna-Cabello, Paddy M, Brock, Tom S, Churcher, Katarzyna A, Sala, Sara E, Zakutansky, María Belén, Jiménez-Díaz, Laura Maria, Sanz, Jennifer, Riley, Rajshekhar, Basak, Michael, Campbell, Vicky M, Avery, Robert W, Sauerwein, Koen J, Dechering, Rintis, Noviyanti, Brice, Campo, Julie A, Frearson, Iñigo, Angulo-Barturen, Santiago, Ferrer-Bazaga, Francisco Javier, Gamo, Paul G, Wyatt, Didier, Leroy, Peter, Siegl, Michael J, Delves, Dennis E, Kyle, Sergio, Wittlin, Jutta, Marfurt, Ric N, Price, Robert E, Sinden, Elizabeth A, Winzeler, Susan A, Charman, Lidiya, Bebrevska, David W, Gray, Simon, Campbell, Alan H, Fairlamb, Paul A, Willis, Julian C, Rayner, David A, Fidock, Kevin D, Read, Ian H, Gilbert

المساهمون: Medicines for Malaria Venture, Medical Research Council (MRC)

المصدر: Nature, 522, 315-20
Nature, 522, 7556, pp. 315-20
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid

مصطلحات موضوعية: Male, Models, Molecular, Plasmodium, TRANSMISSION, General Science & Technology, Plasmodium berghei, Plasmodium vivax, Plasmodium falciparum, lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4], Drug resistance, Computational biology, MALARIA CONTROL, Antimalarials, GAMETOCYTES, Peptide Elongation Factor 2, ELONGATION-FACTOR 2, MD Multidisciplinary, Drug Discovery, Animals, Antimalarial Agent, VIVAX, Life Cycle Stages, Science & Technology, Multidisciplinary, PLASMODIUM-FALCIPARUM, IDENTIFICATION, biology, Drug discovery, Chemoprotection, biology.organism_classification, 3. Good health, Malaria, Multidisciplinary Sciences, Drug development, Gene Expression Regulation, Liver, NEXT-GENERATION, Protein Biosynthesis, Quinolines, Science & Technology - Other Topics, POPULATIONS, Female