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1دورية أكاديمية
المؤلفون: Mark van Breugel, Rainer Wilcken, Stephen H McLaughlin, Trevor J Rutherford, Christopher M Johnson
المصدر: eLife, Vol 3 (2014)
مصطلحات موضوعية: centriole, basal body, SAS-6, centrosome, Leishmania, trypanosomatid, Medicine, Science, Biology (General), QH301-705.5
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: Matthias Rupp, Matthias R Bauer, Rainer Wilcken, Andreas Lange, Michael Reutlinger, Frank M Boeckler, Gisbert Schneider
المصدر: PLoS Computational Biology, Vol 10, Iss 1, p e1003400 (2014)
مصطلحات موضوعية: Biology (General), QH301-705.5
وصف الملف: electronic resource
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3
المؤلفون: Edwige Lorthiois, Marc Gerspacher, Kim S. Beyer, Andrea Vaupel, Catherine Leblanc, Rowan Stringer, Andreas Weiss, Rainer Wilcken, Daniel A. Guthy, Andreas Lingel, Claudio Bomio-Confaglia, Rainer Machauer, Pascal Rigollier, Johannes Ottl, Dorothee Arz, Pascal Bernet, Gaëlle Desjonqueres, Solene Dussauge, Malika Kazic-Legueux, Marie-Anne Lozac’h, Christophe Mura, Mickaël Sorge, Milen Todorov, Nicolas Warin, Florence Zink, Hans Voshol, Frederic J. Zecri, Richard C. Sedrani, Nils Ostermann, Saskia M. Brachmann, Simona Cotesta
المصدر: Journal of Medicinal Chemistry. 65:16173-16203
مصطلحات موضوعية: Drug Discovery, Molecular Medicine
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4
المؤلفون: Saskia M. Brachmann, Simona Cotesta, Anna F. Farago, Frederic Zecri, Kun Xu, Rainer Wilcken, Toni Widmer, Peter Wessels, Hans Voshol, Andrea Vaupel, Rowan Stringer, Toshio Shimizu, Richard Sedrani, Christian Schnell, Danielle Roman, Pascal Rigollier, Johannes Ottl, Nils Ostermann, Helen Oakman, Jason Murphy, Sauveur-Michel Maira, Catherine Leblanc, Jeffrey D. Kearns, Eloísa Jiménez Núñez, Ashley Jaeger, Victoria Head, Daniel Alexander Guthy, Marc Gerspacher, Carmine Fedele, Lekshmi Dharmarajan, Ruben de Kanter, Xiaoming Cui, Xueying Chen, Heather Burks, Claudio Bomio-Confaglia, Kim S. Beyer, Louise Barys, Edwige Lorthiois, Andreas Weiss
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d58af020ff3289026b12e3df1b9a0f4
https://doi.org/10.1158/2159-8290.22541471.v1 -
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المؤلفون: Saskia M. Brachmann, Simona Cotesta, Anna F. Farago, Frederic Zecri, Kun Xu, Rainer Wilcken, Toni Widmer, Peter Wessels, Hans Voshol, Andrea Vaupel, Rowan Stringer, Toshio Shimizu, Richard Sedrani, Christian Schnell, Danielle Roman, Pascal Rigollier, Johannes Ottl, Nils Ostermann, Helen Oakman, Jason Murphy, Sauveur-Michel Maira, Catherine Leblanc, Jeffrey D. Kearns, Eloísa Jiménez Núñez, Ashley Jaeger, Victoria Head, Daniel Alexander Guthy, Marc Gerspacher, Carmine Fedele, Lekshmi Dharmarajan, Ruben de Kanter, Xiaoming Cui, Xueying Chen, Heather Burks, Claudio Bomio-Confaglia, Kim S. Beyer, Louise Barys, Edwige Lorthiois, Andreas Weiss
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::090908cffff39039ae33828ed26022f4
https://doi.org/10.1158/2159-8290.c.6549647 -
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المؤلفون: Andreas Weiss, Edwige Lorthiois, Louise Barys, Kim S. Beyer, Claudio Bomio-Confaglia, Heather Burks, Xueying Chen, Xiaoming Cui, Ruben de Kanter, Lekshmi Dharmarajan, Carmine Fedele, Marc Gerspacher, Daniel Alexander Guthy, Victoria Head, Ashley Jaeger, Eloísa Jiménez Núñez, Jeffrey D. Kearns, Catherine Leblanc, Sauveur-Michel Maira, Jason Murphy, Helen Oakman, Nils Ostermann, Johannes Ottl, Pascal Rigollier, Danielle Roman, Christian Schnell, Richard Sedrani, Toshio Shimizu, Rowan Stringer, Andrea Vaupel, Hans Voshol, Peter Wessels, Toni Widmer, Rainer Wilcken, Kun Xu, Frederic Zecri, Anna F. Farago, Simona Cotesta, Saskia M. Brachmann
المصدر: Cancer Discovery. 12:1500-1517
مصطلحات موضوعية: Proto-Oncogene Proteins p21(ras), Indazoles, Oncology, Neoplasms, Mutation, Humans, Enzyme Inhibitors
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2edd83624df412b8b1d836bfe665fa6
https://doi.org/10.1158/2159-8290.cd-22-0158 -
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المؤلفون: Stephane Rodde, Anikó Udvarhelyi, Rainer Wilcken
المصدر: Journal of Computer-Aided Molecular Design. 35:399-415
مصطلحات موضوعية: Models, Molecular, Computer science, Molecular Conformation, 01 natural sciences, Quantum chemistry, Workflow, Small Molecule Libraries, COSMO-RS, 0103 physical sciences, Drug Discovery, Molecule, Physical and Theoretical Chemistry, Conformational isomerism, 010304 chemical physics, Drug discovery, Pillar, 0104 chemical sciences, Computer Science Applications, 010404 medicinal & biomolecular chemistry, Models, Chemical, Pharmaceutical Preparations, Solubility, Solvents, Quantum Theory, Thermodynamics, Biochemical engineering
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8
المؤلفون: Wolfgang Jahnke, José A. Márquez, Andreas Marzinzik, Irina Cornaciu, Christian Schleberger, Lena Münzker, Joy Kristin Petrick, Gerhard Klebe, Rainer Wilcken, Damien Clavel
المصدر: ChemBioChem. 21:3096-3111
مصطلحات موضوعية: Models, Molecular, Antiparasitic, medicine.drug_class, Trypanosoma brucei brucei, Allosteric regulation, Farnesyl pyrophosphate, Trypanosoma brucei, 010402 general chemistry, 01 natural sciences, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, parasitic diseases, medicine, Enzyme Inhibitors, Binding site, Molecular Biology, Binding Sites, Molecular Structure, ATP synthase, biology, 010405 organic chemistry, Drug discovery, Chemistry, Organic Chemistry, Geranyltranstransferase, biology.organism_classification, 0104 chemical sciences, 3. Good health, Structural biology, biology.protein, Molecular Medicine
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9
المؤلفون: Amanda Littlewood-Evans, Simona Cotesta, Philipp Janser, Rochdi Bouhelal, Rowan Stringer, Stephanie Harlfinger, Philippe Piechon, Rainer Wilcken, Matthias Haffke, Fabian Piller, Frederic Villard, Dominique Fehlmann, Trixie Wagner, Klemens Kaupmann, Achim Schlapbach, Nina Gommermann, Juraj Velcicky
المصدر: Journal of medicinal chemistry. 63(17)
مصطلحات موضوعية: Male, Static Electricity, Plasma protein binding, 01 natural sciences, Cell Line, Receptors, G-Protein-Coupled, 03 medical and health sciences, Static electricity, Drug Discovery, Succinate receptor 1, Animals, Humans, 030304 developmental biology, Phenylacetates, 0303 health sciences, Chemistry, Drug discovery, Antagonist, Permeation, Salt bridge (protein and supramolecular), Combinatorial chemistry, 0104 chemical sciences, Bioavailability, Rats, Mice, Inbred C57BL, 010404 medicinal & biomolecular chemistry, Benzamides, Molecular Medicine, Protein Binding
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10
المؤلفون: Stephane Rodde, Anikó Udvarhelyi, Stefan Grimme, Rainer Wilcken, Philipp Pracht
المصدر: Journal of Computer-Aided Molecular Design. 32:1139-1149
مصطلحات موضوعية: Models, Molecular, Implicit solvation, Molecular Conformation, Datasets as Topic, Context (language use), Free-energy relationship, 010402 general chemistry, Heterocyclic Compounds, 2-Ring, 01 natural sciences, Quantum chemistry, 0103 physical sciences, Drug Discovery, Molecule, Computer Simulation, Statistical physics, Physics::Chemical Physics, Physical and Theoretical Chemistry, Quantum chemical, Physics, Quantitative Biology::Biomolecules, 010304 chemical physics, Stereoisomerism, Hydrogen-Ion Concentration, 0104 chemical sciences, Computer Science Applications, Models, Chemical, Solvents, Quantum Theory, Thermodynamics, Free energies, Density functional theory