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المؤلفون: Goodman VL; Division of Drug Oncology Products, U.S. Food and Drug Administration, Sliver Spring, Maryland 20903, USA. vicki.goodman@fda.hhs.gov, Rock EP, Dagher R, Ramchandani RP, Abraham S, Gobburu JV, Booth BP, Verbois SL, Morse DE, Liang CY, Chidambaram N, Jiang JX, Tang S, Mahjoob K, Justice R, Pazdur R

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2007 Mar 01; Vol. 13 (5), pp. 1367-73.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Print ISSN: 1078-0432 (Print) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*therapeutic use , Carcinoma, Renal Cell/*drug therapy , Gastrointestinal Stromal Tumors/*drug therapy , Indoles/*therapeutic use , Kidney Neoplasms/*drug therapy , Piperazines/*therapeutic use , Pyrimidines/*therapeutic use , Pyrroles/*therapeutic use, Benzamides ; Drug Approval ; Drug Resistance, Neoplasm ; Humans ; Imatinib Mesylate ; Randomized Controlled Trials as Topic ; Sunitinib ; United States ; United States Food and Drug Administration

المؤلفون: Bhattaram VA; Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, USA., Bonapace C, Chilukuri DM, Duan JZ, Garnett C, Gobburu JV, Jang SH, Kenna L, Lesko LJ, Madabushi R, Men Y, Powell JR, Qiu W, Ramchandani RP, Tornoe CW, Wang Y, Zheng JJ

المصدر: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2007 Feb; Vol. 81 (2), pp. 213-21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print Cited Medium: Print ISSN: 0009-9236 (Print) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE

مواضيع طبية MeSH: Pharmacokinetics* , Pharmacology, Clinical*, Drug Approval/*legislation & jurisprudence , Drug Labeling/*legislation & jurisprudence, Benzazepines/administration & dosage ; Benzazepines/adverse effects ; Benzazepines/therapeutic use ; Clinical Trials as Topic/methods ; Cyclosporins/administration & dosage ; Cyclosporins/adverse effects ; Cyclosporins/therapeutic use ; Data Collection ; Decision Support Techniques ; Disease Progression ; Drug Administration Schedule ; Drug Evaluation/methods ; Echinocandins ; Everolimus ; Humans ; Investigational New Drug Application/legislation & jurisprudence ; Investigational New Drug Application/statistics & numerical data ; Lipopeptides ; Lipoproteins/administration & dosage ; Lipoproteins/adverse effects ; Lipoproteins/therapeutic use ; Micafungin ; Peer Review ; Peptides, Cyclic/administration & dosage ; Peptides, Cyclic/adverse effects ; Peptides, Cyclic/therapeutic use ; Quinoxalines/administration & dosage ; Quinoxalines/adverse effects ; Quinoxalines/therapeutic use ; Risk Assessment/methods ; Sirolimus/administration & dosage ; Sirolimus/adverse effects ; Sirolimus/analogs & derivatives ; Sirolimus/therapeutic use ; Treatment Outcome ; United States ; United States Food and Drug Administration/legislation & jurisprudence ; United States Food and Drug Administration/standards ; Varenicline

المؤلفون: Ramchandani RP; Office of Clinical Pharmacology, Center for Drug Evaluation and Research, US Food and Drug Administration, WO21 Rm 3667, 10903 New Hampshire Ave, Silver Spring, MD 20993, USA. roshni.ramchandani@fda.hhs.gov, Wang Y, Booth BP, Ibrahim A, Johnson JR, Rahman A, Mehta M, Innocenti F, Ratain MJ, Gobburu JV

المصدر: Journal of clinical pharmacology [J Clin Pharmacol] 2007 Jan; Vol. 47 (1), pp. 78-86.

نوع المنشور: Comparative Study; Journal Article

بيانات الدورية: Publisher: Wiley Country of Publication: England NLM ID: 0366372 Publication Model: Print Cited Medium: Print ISSN: 0091-2700 (Print) Linking ISSN: 00912700 NLM ISO Abbreviation: J Clin Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Polymorphism, Genetic*, Antineoplastic Agents, Phytogenic/*metabolism , Bilirubin/*metabolism , Camptothecin/*analogs & derivatives , Glucuronosyltransferase/*genetics , Lymphoma/*drug therapy , Neutropenia/*chemically induced, Antineoplastic Agents, Phytogenic/adverse effects ; Antineoplastic Agents, Phytogenic/therapeutic use ; Area Under Curve ; Camptothecin/adverse effects ; Camptothecin/metabolism ; Camptothecin/therapeutic use ; Female ; Humans ; Irinotecan ; Lymphoma/genetics ; Male ; Models, Biological ; Regression Analysis