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1
المؤلفون: Manfred Schubert-Zsilavecz, Roberto Carrasco Gomez, Daniel Flesch, Holger Stark, Matthias Gabler, Ramona Steri, Andreas Lill, Gisbert Schneider, Daniel Merk
المصدر: Bioorganic & Medicinal Chemistry. 23:3490-3498
مصطلحات موضوعية: Agonist, Cell Survival, medicine.drug_class, Clinical Biochemistry, Regulator, Gene Expression, Receptors, Cytoplasmic and Nuclear, Pharmaceutical Science, Crystallography, X-Ray, Ligands, Transfection, Biochemistry, Protein Structure, Secondary, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, medicine, Humans, Moiety, Isoxazole, Molecular Biology, Transcription factor, Chemistry, Ligand, Hydrolysis, Organic Chemistry, Hep G2 Cells, Isoxazoles, Protein Structure, Tertiary, Molecular Docking Simulation, Nuclear receptor, Molecular Medicine, Farnesoid X receptor, HeLa Cells, Plasmids
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2
المؤلفون: Sascha Weggen, Ramona Steri, Isabella Ogorek, Sven Popella, Oliver Werz, Gerd Dannhardt, Manfred Schubert-Zsilavecz, Julia Ness, Martina Hieke, Friederike Dehm, Daniel Flesch, Christina Lamers
المصدر: Bioorganic & Medicinal Chemistry Letters. 25:841-846
مصطلحات موضوعية: Clinical Biochemistry, Pharmaceutical Science, Peroxisome proliferator-activated receptor, Inflammation, Disease, Pharmacology, Inhibitory postsynaptic potential, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Alzheimer Disease, Drug Discovery, medicine, Humans, Lipoxygenase Inhibitors, γ secretase, Caproates, Molecular Biology, Hexanoic acid, chemistry.chemical_classification, Arachidonate 5-Lipoxygenase, biology, Organic Chemistry, PPAR gamma, chemistry, Arachidonate 5-lipoxygenase, biology.protein, Molecular Medicine, Amyloid Precursor Protein Secretases, medicine.symptom, Derivative (chemistry)
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3
المؤلفون: Ramona Steri, Miriam Ude
المصدر: Pharmazie in unserer Zeit. 41:409-415
مصطلحات موضوعية: Pharmacology, Pharmaceutical Science, Pharmacology (medical)
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4
المؤلفون: Oliver Werz, Sascha Weggen, Martina Hieke, Ramona Steri, Manfred Schubert-Zsilavecz, Heiko Zettl, Christine Greiner, Julia Ness
المصدر: Bioorganic & Medicinal Chemistry. 19:5372-5382
مصطلحات موضوعية: Cell Survival, Stereochemistry, Clinical Biochemistry, Molecular Conformation, Pharmaceutical Science, Peroxisome proliferator-activated receptor, Stereoisomerism, CHO Cells, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Cricetinae, Chlorocebus aethiops, Drug Discovery, Animals, Humans, Structure–activity relationship, Cyclooxygenase Inhibitors, Caproates, Molecular Biology, Hexanoic acid, chemistry.chemical_classification, Sheep, COS cells, Dose-Response Relationship, Drug, biology, Chemistry, Chinese hamster ovary cell, Organic Chemistry, Biological activity, Combinatorial chemistry, Recombinant Proteins, PPAR gamma, Cyclooxygenase 2, COS Cells, Cyclooxygenase 1, biology.protein, Molecular Medicine, Amyloid Precursor Protein Secretases, Amyloid precursor protein secretase
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5
المؤلفون: Maren Pellowska, Alexander Paulke, Ralf P. Brandes, Ralph T. Schermuly, Thorsten J. Maier, Anja Mieth, Mario Wurglics, Manfred Schubert-Zsilavecz, Ramona Steri, AS Fischer, Gerd Geisslinger, M Revermann, Dieter Steinhilber, Laura Popescu
المصدر: British Journal of Pharmacology. 163:1721-1732
مصطلحات موضوعية: Pharmacology, Epoxide hydrolase 2, medicine.medical_specialty, Monocyte, Prostaglandin, Biology, Angiotensin II, Vascular remodelling in the embryo, chemistry.chemical_compound, medicine.anatomical_structure, Endocrinology, chemistry, Internal medicine, Arachidonate 5-lipoxygenase, cardiovascular system, medicine, biology.protein, Pirinixic Acid, lipids (amino acids, peptides, and proteins), Arachidonic acid
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6
المؤلفون: Sabine Grösch, Gerd Geisslinger, Florian Rörsch, Manfred Schubert-Zsilavecz, Klaus Deckmann, Ramona Steri
المصدر: Biochemical Pharmacology. 80:1365-1372
مصطلحات موضوعية: musculoskeletal diseases, Sp1 Transcription Factor, Interleukin-1beta, EGR1, CREB, Biochemistry, chemistry.chemical_compound, Humans, Cyclic AMP Response Element-Binding Protein, Promoter Regions, Genetic, Transcription factor, Early Growth Response Protein 1, Prostaglandin-E Synthases, Pharmacology, Sulfonamides, Reporter gene, Binding Sites, biology, Tumor Necrosis Factor-alpha, NF-kappa B, NF-κB, Promoter, Biological activity, Molecular biology, Intramolecular Oxidoreductases, chemistry, biology.protein, Pyrazoles, lipids (amino acids, peptides, and proteins), Cyclooxygenase, HeLa Cells
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7
المؤلفون: Manfred Schubert-Zsilavecz, Ramona Steri, Katja Hansen, Oliver Schwarz, Ewgenij Proschak, Gisbert Schneider, Heiko Zettl, Lutz Müller-Kuhrt, Timon Schroeter, Klaus-Robert Müller, Matthias Rupp
المصدر: Bioorganic & Medicinal Chemistry Letters. 20:2920-2923
مصطلحات موضوعية: Peroxisome proliferator-activated receptor gamma, Clinical Biochemistry, Pharmaceutical Science, Peroxisome proliferator-activated receptor, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Humans, Hypoglycemic Agents, Computer Simulation, Molecular Biology, Transcription factor, chemistry.chemical_classification, Reporter gene, Binding Sites, Activator (genetics), Chemistry, Truxillic acid, Organic Chemistry, PPAR gamma, Glucose, Nuclear receptor, Molecular Medicine, Peroxisome proliferator-activated receptor alpha, Cyclobutanes
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8
المؤلفون: Ramona Steri, Gisbert Schneider, Manfred Schubert-Zsilavecz, Theresa M. Thieme, Ewgenij Proschak, Alexander Paulke
المصدر: Bioorganic & Medicinal Chemistry Letters. 20:2469-2473
مصطلحات موضوعية: Models, Molecular, Agonist, medicine.medical_specialty, medicine.drug_class, Clinical Biochemistry, Pharmaceutical Science, Peroxisome proliferator-activated receptor, Pharmacology, Biochemistry, Internal medicine, Drug Discovery, medicine, Receptor, Molecular Biology, Cholesterol homeostasis, chemistry.chemical_classification, Organic Chemistry, Rational design, Peroxisome, Subtype selective, PPAR gamma, Pyrimidines, Endocrinology, chemistry, Drug Design, Pirinixic Acid, Molecular Medicine
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9
المؤلفون: Ramona Steri, Manfred Schubert-Zsilavecz
المصدر: Pharmazie in unserer Zeit. 39:142-146
مصطلحات موضوعية: Pharmacology, Gynecology, medicine.medical_specialty, business.industry, medicine, Pharmaceutical Science, Pharmacology (medical), business
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10
المصدر: Bioorganic & Medicinal Chemistry Letters. 19:4421-4426
مصطلحات موضوعية: Stereochemistry, Chemistry, Pharmaceutical, Carboxylic acid, Clinical Biochemistry, Chemistry, Organic, Drug Evaluation, Preclinical, Pharmaceutical Science, Peroxisome proliferator-activated receptor, chemistry.chemical_element, Biochemistry, Chemical synthesis, Structure-Activity Relationship, Drug Discovery, Combinatorial Chemistry Techniques, Humans, PPAR alpha, Sulfhydryl Compounds, Caproates, Molecular Biology, chemistry.chemical_classification, Molecular Structure, Phenol, Chemistry, Activator (genetics), Organic Chemistry, Sulfur, Carbon, Models, Chemical, Nuclear receptor, Drug Design, Molecular Medicine, Aliphatic compound, Selectivity