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1
المؤلفون: Zhihong Lai, Kevin E. Wee, Randine L. Dowling, Jeanne I. Corman, Richard Wynn, Jianhong Ma, Robert A. Copeland, Cristy S. Dougherty, Kurt R. Auger, Kurumi Y. Horiuchi
المصدر: Journal of Protein Chemistry. 19:489-498
مصطلحات موضوعية: Models, Molecular, Ubiquitin-Protein Ligases, Ubiquitin-activating enzyme, Kinetics, Population, Ubiquitin-Activating Enzymes, Binding, Competitive, Biochemistry, Substrate Specificity, Ligases, Ubiquitin, Humans, Bioorganic chemistry, Protein Structure, Quaternary, education, Ubiquitins, chemistry.chemical_classification, education.field_of_study, biology, Substrate (chemistry), Fluoresceins, Enzyme, chemistry, biology.protein, Steady state (chemistry), Ultracentrifugation
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2
المؤلفون: Bruce D. Jaffee, Ronald L. Magolda, Tracy L. Taylor, Douglas G. Batt, Susan R. Sherk, Joseph J. Petraitis, Randine L. Dowling, Robert A. Copeland, Elizabeth A. Jones
المصدر: Bioorganic & Medicinal Chemistry Letters. 8:1745-1750
مصطلحات موضوعية: Bicyclic molecule, Stereochemistry, Biphenyl Compounds, Organic Chemistry, Clinical Biochemistry, Quinoline, Heteroatom, Substituent, Pharmaceutical Science, Mixed lymphocyte reaction, Biochemistry, Chemical synthesis, Carbon, Structure-Activity Relationship, chemistry.chemical_compound, chemistry, Drug Discovery, Lipophilicity, Dihydroorotate dehydrogenase, Molecular Medicine, Lymphocyte Culture Test, Mixed, Molecular Biology, Immunosuppressive Agents
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3
المؤلفون: Douglas G. Batt, Elizabeth A. Jones, Donald J. P. Pinto, Pitts William J, Joseph J. Petraitis, Susan R. Sherk, Michael J. Orwat, Robert A. Copeland, Bruce D. Jaffee, Ronald L. Magolda, Randine L. Dowling, Tracy L. Gardner, Irina Cipora Jacobson, James W. Jetter
المصدر: Bioorganic & Medicinal Chemistry Letters. 8:307-312
مصطلحات موضوعية: Oxidoreductases Acting on CH-CH Group Donors, Molecular model, Stereochemistry, Clinical Biochemistry, Heteroatom, Dihydroorotate Dehydrogenase, Pharmaceutical Science, Ring (chemistry), Biochemistry, Chemical synthesis, Structure-Activity Relationship, Heterocyclic Compounds, Drug Discovery, Humans, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, biology, Biphenyl Compounds, Organic Chemistry, Mixed lymphocyte reaction, Enzyme, chemistry, Enzyme inhibitor, Dihydroorotate dehydrogenase, biology.protein, Molecular Medicine, Lymphocyte Culture Test, Mixed, Oxidoreductases, Immunosuppressive Agents
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4
المؤلفون: Kathleen Murphy, Barbara H. Wiswall, John Giannaras, Randine L. Dowling, Gregory Hollis, Petra Marchand, Henry J. George, Robert A. Copeland, James M. Trzaskos
المصدر: Protein Expression and Purification. 10:154-161
مصطلحات موضوعية: Phenylmercuric Acetate, Recombinant Fusion Proteins, medicine.medical_treatment, Genetic Vectors, Molecular Sequence Data, Moths, Spodoptera, MMP9, Chromatography, Affinity, law.invention, Species Specificity, FLAG-tag, law, Zymogen, medicine, Trichoplusia, Animals, Humans, Gelatinase, Amino Acid Sequence, Collagenases, Cloning, Molecular, Enzyme Precursors, Protease, biology, biology.organism_classification, Molecular biology, Nucleopolyhedroviruses, In vitro, Enzyme Activation, Kinetics, Microbial Collagenase, Matrix Metalloproteinase 9, Biochemistry, Recombinant DNA, Peptides, Biotechnology
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5
المؤلفون: Sherrill Nurnberg, Nicholas L. Rider, James M. Trzaskos, Donald J. P. Pinto, Maryanne B. Covington, Jean M. Williams, John Giannaras, June P. Davis, Randine L. Dowling, Michael J. Orwat, Robert A. Copeland
المصدر: Journal of Enzyme Inhibition. 10:73-79
مصطلحات موضوعية: Gene isoform, 3-Hydroxysteroid Dehydrogenases, Indomethacin, Alpha (ethology), Ibuprofen, Dehydrogenase, macromolecular substances, Pharmacology, Biochemistry, Isozyme, Leukocytes, Humans, Cyclooxygenase Inhibitors, Enzyme Inhibitors, Polycyclic Aromatic Hydrocarbons, Hydroxysteroid dehydrogenase, Peroxidase, chemistry.chemical_classification, Cyclooxygenase 2 Inhibitors, biology, Chemistry, Anti-Inflammatory Agents, Non-Steroidal, Membrane Proteins, Recombinant Proteins, Isoenzymes, Kinetics, Enzyme, Cyclooxygenase 2, Prostaglandin-Endoperoxide Synthases, Myeloperoxidase, Cyclooxygenase 1, biology.protein, Molecular Medicine, Cyclooxygenase
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6
المؤلفون: Douglas G. Batt, Bruce D. Jaffee, Donald J. P. Pinto, Elizabeth A. Jones, Tracy L. Gardner, Randine L. Dowling, Pitts William J, Ronald L. Magolda, Michael J. Orwat, Robert A. Copeland
المصدر: Bioorganic & Medicinal Chemistry Letters. 5:1549-1554
مصطلحات موضوعية: Stereochemistry, Chemistry, Organic Chemistry, Clinical Biochemistry, Drug Discovery, Dihydroorotate dehydrogenase, Pharmaceutical Science, Molecular Medicine, Cinchoninic acid, Mixed lymphocyte reaction, Molecular Biology, Biochemistry
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7
المصدر: Protein expression and purification. 7(4)
مصطلحات موضوعية: Phenylmercuric Acetate, Saccharomyces cerevisiae, Genetic Vectors, Molecular Sequence Data, Gene Expression, Pichia, Pichia pastoris, law.invention, Fungal Proteins, law, Complementary DNA, Humans, Amino Acid Sequence, Collagenases, DNA, Fungal, Peptide sequence, Expression vector, biology, Fungal genetics, Sodium Dodecyl Sulfate, Fibroblasts, biology.organism_classification, Molecular biology, Yeast, Recombinant Proteins, Enzyme Activation, Biochemistry, Recombinant DNA, Electrophoresis, Polyacrylamide Gel, Matrix Metalloproteinase 1, Sequence Analysis, Biotechnology
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8
المؤلفون: Thomas A. Patterson, Randine L. Dowling, Diane Lombardo, June P. Davis, Robert A. Copeland, Kathleen Murphy
المصدر: Archives of biochemistry and biophysics. 323(1)
مصطلحات موضوعية: Oxidoreductases Acting on CH-CH Group Donors, Molecular Sequence Data, Biophysics, Dihydroorotate Dehydrogenase, Biochemistry, Enzyme Repression, law.invention, Enzyme activator, Non-competitive inhibition, law, Escherichia coli, Animals, Humans, Amino Acid Sequence, Enzyme inducer, Molecular Biology, Dihydroorotate Dehydrogenase Inhibitor, chemistry.chemical_classification, biology, Molecular biology, Recombinant Proteins, Enzyme Activation, Enzyme, chemistry, biology.protein, Dihydroorotate dehydrogenase, Recombinant DNA, Cattle, Oxidoreductases
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9
المؤلفون: Andrea J. Daulerio, Steven Culp, Robert C. Newton, Randine L. Dowling
المصدر: Journal of immunological methods. 161(2)
مصطلحات موضوعية: Male, Chromatography, medicine.diagnostic_test, biology, medicine.drug_class, Immunology, Enzyme-Linked Immunosorbent Assay, Assay sensitivity, Monoclonal antibody, Molecular biology, Sensitivity and Specificity, Sepharose, Mice, Inbred C57BL, Mice, Affinity chromatography, Polyclonal antibodies, Immunoassay, medicine, biology.protein, Immunology and Allergy, Animals, Rabbits, Antibody, Beta (finance), Interleukin-1