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1دورية أكاديمية
المؤلفون: Scolnick, E., Rands, E., Aaronson, S. A., Todaro, G. J.
المصدر: Proceedings of the National Academy of Sciences of the United States of America, 1970 Dec . 67(4), 1789-1796.
URL الوصول: https://www.jstor.org/stable/60570
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2
المؤلفون: S J deSolms, Rands E, Jackson B. Gibbs, Catherine M. Wiscount, Scholz Th, Robert L. Smith, Kenneth S. Koblan, Nancy E. Kohl, E A Giuliani, David L. Pompliano, Scott D. Mosser, Oliff Allen I, Samuel L. Graham
المصدر: Journal of Medicinal Chemistry. 41:2651-2656
مصطلحات موضوعية: Stereochemistry, Farnesyltransferase, Naphthalenes, Oncogene Protein p21(ras), Chemical synthesis, Mice, Structure-Activity Relationship, Prenylation, Drug Discovery, Animals, Farnesyltranstransferase, Structure–activity relationship, Prodrugs, Enzyme Inhibitors, Cell Line, Transformed, chemistry.chemical_classification, Farnesyl-diphosphate farnesyltransferase, Alkyl and Aryl Transferases, biology, Tetrapeptide, Chemistry, Molecular Mimicry, Esters, 3T3 Cells, Rats, Enzyme, Enzyme inhibitor, biology.protein, Molecular Medicine, Oligopeptides, Protein Processing, Post-Translational, Cell Division
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3
المؤلفون: Theresa M. Williams, Rands E, Nancy E. Kohl, George D. Hartman, Samuel L. Graham, Kelly Hamilton, Timothy J. O'Neill, Oliff Allen I, Christopher J. Dinsmore, Kenneth S. Koblan, Jackson B. Gibbs
المصدر: Bioorganic & Medicinal Chemistry Letters. 7:1345-1348
مصطلحات موضوعية: chemistry.chemical_classification, Farnesyl-diphosphate farnesyltransferase, biology, Farnesyl Protein Transferase, Tetrapeptide, medicine.drug_class, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Carboxamide, Biochemistry, Chemical synthesis, Enzyme, chemistry, Enzyme inhibitor, Drug Discovery, medicine, biology.protein, Molecular Medicine, Transferase, Molecular Biology
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4
المؤلفون: Dona L. Bamberger, Jackson B. Gibbs, Oliff Allen I, Nancy E. Kohl, Samuel L. Graham, Rands E, Thorsten E. Fisher, Robert L. Smith, Scott D. Mosser, John S. Wai, David L. Pompliano
المصدر: Bioorganic & Medicinal Chemistry. 2:939-947
مصطلحات موضوعية: Farnesyl Protein Transferase, Stereochemistry, Molecular Sequence Data, Clinical Biochemistry, Pharmaceutical Science, chemistry.chemical_element, Biochemistry, 3T3 cells, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Transferases, Drug Discovery, Ic50 values, medicine, Animals, Potency, Amino Acid Sequence, Methylene, Molecular Biology, Alkyl and Aryl Transferases, Molecular Structure, Tetrapeptide, Chemistry, Organic Chemistry, Stereoisomerism, Biological activity, 3T3 Cells, Cell Transformation, Viral, Genes, ras, medicine.anatomical_structure, Molecular Medicine, Oligopeptides, Carbon
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5
المؤلفون: Michael J. Breslin, Samuel L. Graham, Scott D. Mosser, Deana Aa, Rands E, Oliff Allen I, S J deSolms, Nancy E. Kohl, David L. Pompliano, E A Giuliani
المصدر: Journal of Medicinal Chemistry. 37:725-732
مصطلحات موضوعية: Farnesyl Protein Transferase, Stereochemistry, Molecular Sequence Data, Protein Prenylation, Homoserine, Structure-Activity Relationship, chemistry.chemical_compound, Prenylation, Transferases, Drug Discovery, Animals, Farnesyltranstransferase, Transferase, Amino Acid Sequence, Cells, Cultured, chemistry.chemical_classification, Farnesyl-diphosphate farnesyltransferase, Alkyl and Aryl Transferases, biology, Tetrapeptide, Stereoisomerism, Dipeptides, Enzyme, chemistry, Biochemistry, Enzyme inhibitor, biology.protein, Molecular Medicine, Cattle, Oligopeptides
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6
المؤلفون: Scott D. Mosser, Sheo B. Singh, Russell B. Lingham, Jackson B. Gibbs, Rands E, Edward M. Scolnick, David L. Pompliano, Oliff Allen I, Nancy E. Kohl
المصدر: Journal of Biological Chemistry. 268:7617-7620
مصطلحات موضوعية: chemistry.chemical_classification, biology, Farnesyl Protein Transferase, Farnesyltransferase, Biological activity, Zaragozic acid, Cell Biology, Biochemistry, chemistry.chemical_compound, Enzyme, chemistry, Prenylation, Enzyme inhibitor, biology.protein, Transferase, Molecular Biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0269c733afb5faa972e12c9961ab15ca
https://doi.org/10.1016/s0021-9258(18)52998-7 -
7
المؤلفون: Robert B. Lobell, J. Christopher Culberson, Jackson B. Gibbs, Christopher J. Dinsmore, Kenneth S. Koblan, Theresa M. Williams, Nancy E. Kohl, Dongming Liu, Rands E, Timothy J. O'Neill
المصدر: ChemInform. 31
مصطلحات موضوعية: chemistry.chemical_compound, Farnesyl Protein Transferase, chemistry, Stereochemistry, Imidazole, General Medicine
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8
المؤلفون: Rands E, Kenneth S. Koblan, Robert B. Lobell, Samuel L. Graham, Dongming Liu, Jackson B. Gibbs, J. Christopher Culberson, George D. Hartman, Theresa M. Williams, Nancy E. Kohl, Christopher J. Dinsmore, Oliff Allen I, Timothy J. O'Neill
المصدر: Bioorganicmedicinal chemistry letters. 9(23)
مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Molecular model, Farnesyl Protein Transferase, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Chemical synthesis, Sulfone, chemistry.chemical_compound, Drug Discovery, Transferase, Humans, Sulfones, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, Farnesyl-diphosphate farnesyltransferase, Alkyl and Aryl Transferases, biology, Molecular Structure, Organic Chemistry, Imidazoles, Enzyme, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine, Ethers
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9
المؤلفون: Rands E, Samuel L. Graham, George D. Hartman, Nancy E. Kohl, Micheal D. Schaber, Robert P. Gomez, Oliff Allen I, Daksha Shah, Neville J. Anthony, Scott D. Mosser, Kelly Hamilton, Timothy J. O'Neil, Kenneth S. Koblan, Jackson B. Gibbs
المصدر: Journal of medicinal chemistry. 42(17)
مصطلحات موضوعية: Farnesyl Protein Transferase, medicine.drug_class, Stereochemistry, Mice, Nude, Carboxamide, Antineoplastic Agents, Mice, Transgenic, Chemical synthesis, Proto-Oncogene Proteins p21(ras), Mice, Structure-Activity Relationship, Drug Discovery, medicine, Animals, Prodrugs, Enzyme Inhibitors, Cell Line, Transformed, chemistry.chemical_classification, Farnesyl-diphosphate farnesyltransferase, Alkyl and Aryl Transferases, Binding Sites, biology, Imidazoles, 3T3 Cells, Prodrug, In vitro, Enzyme, Biochemistry, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine, Drug Screening Assays, Antitumor, Protein Processing, Post-Translational, Neoplasm Transplantation
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10
المؤلفون: Scott D. Mosser, Samuel L. Graham, Oliff Allen I, E A Giuliani, Rands E, S J deSolms, Deana Aa, David L. Pompliano, Nancy E. Kohl, Scholz Th
المصدر: Journal of medicinal chemistry. 38(20)
مصطلحات موضوعية: Signal peptide, Stereochemistry, Peptidomimetic, Farnesyltransferase, environment and public health, Mice, Structure-Activity Relationship, Prenylation, Transferases, Drug Discovery, Structure–activity relationship, Animals, Enzyme Inhibitors, Farnesyl-diphosphate farnesyltransferase, Alkyl and Aryl Transferases, biology, Tetrapeptide, Chemistry, 3T3 Cells, Amides, Biochemistry, biology.protein, ras Proteins, Molecular Medicine, Protein farnesylation, Peptides