المؤلفون: Thompson, EM, Hielscher, T, Bouffet, E, Remke, M, Luu, B, Gururangan, S, McLendon, RE, Bigner, DD, Lipp, ES, Perreault, S, Cho, YJ, Grant, G, Kim, SK, Lee, JY, Rao, AAN, Giannini, C, Li, KKW, Ng, HK, Yao, Y, Kumabe, T, Tominaga, T, Grajkowska, WA, Perek-Polnik, M, Low, DCY, Seow, WT, Chang, KTE, Mora, J, Pollack, IF, Hamilton, RL, Leary, S, Moore, AS, Ingram, WJ, Hallahan, AR, Jouvet, A, Fèvre-Montange, M, Vasiljevic, A, Faure-Conter, C, Shofuda, T, Kagawa, N, Hashimoto, N, Jabado, N, Weil, AG, Gayden, T, Wataya, T, Shalaby, T, Grotzer, M, Zitterbart, K, Sterba, J, Kren, L, Hortobágyi, T, Klekner, A, László, B, Pócza, T, Hauser, P, Schüller, U, Jung, S, Jang, WY, French, PJ, Kros, JM, van Veelen, MLC, Massimi, L, Leonard, JR, Rubin, JB, Vibhakar, R, Chambless, LB, Cooper, MK, Thompson, RC, Faria, CC, Carvalho, A, Nunes, S, Pimentel, J, Fan, X, Muraszko, KM, López-Aguilar, E, Lyden, D, Garzia, L, Shih, DJH, Kijima, N, Schneider, C, Adamski, J, Northcott, PA, Kool, M, Jones, DTW, Chan, JA, Nikolic, A, Garre, ML, Van Meir, EG, Osuka, S, Olson, JJ, Jahangiri, A, Castro, BA

المصدر: Thompson, EM; Hielscher, T; Bouffet, E; Remke, M; Luu, B; Gururangan, S; et al.(2016). Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis. The Lancet Oncology, 17(4), 484-495. doi: 10.1016/S1470-2045(15)00581-1. UCSF: Retrieved from: http://www.escholarship.org/uc/item/93k1437d

مصطلحات موضوعية: Adult, Male, Canada, Brain Neoplasms, Infant, Prognosis, Magnetic Resonance Imaging, Combined Modality Therapy, Disease-Free Survival, Child, Preschool, Disease Progression, Humans, Female, Child, Medulloblastoma, Retrospective Studies

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od_______325::157ba0eb39a5e706a9db231af7e4ab74
http://www.escholarship.org/uc/item/93k1437d

المؤلفون: Hendrikse LD; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada., Haldipur P; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA., Saulnier O; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada., Millman J; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA., Sjoboen AH; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA., Erickson AW; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Ong W; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Gordon V; Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba, Canada., Coudière-Morrison L; Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba, Canada., Mercier AL; PSL Research University, Université Paris Sud, Université Paris-Saclay, CNRS UMR 3347, INSERM U1021, Institut Curie, Orsay, France., Shokouhian M; Department of Pediatrics and Child Health and Department of Biochemistry and Medical Genetics, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada., Suárez RA; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada., Ly M; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Borlase S; Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba, Canada., Scott DS; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada., Vladoiu MC; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Farooq H; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Sirbu O; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada., Nakashima T; Division of Brain Tumor Translational Research, National Cancer Center Research Institute, Tokyo, Japan., Nambu S; Division of Brain Tumor Translational Research, National Cancer Center Research Institute, Tokyo, Japan., Funakoshi Y; Division of Brain Tumor Translational Research, National Cancer Center Research Institute, Tokyo, Japan., Bahcheli A; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Computational Biology Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Diaz-Mejia JJ; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada., Golser J; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA., Bach K; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA., Phuong-Bao T; Department of Pediatrics and Child Health and Department of Biochemistry and Medical Genetics, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada., Skowron P; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Wang EY; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada., Kumar SA; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Balin P; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Visvanathan A; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada., Lee JJY; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Ayoub R; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada., Chen X; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada., Chen X; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada., Mungall KL; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada., Luu B; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada., Bérubé P; McGill University Genome Centre, McGill University, Montreal, Quebec, Canada., Wang YC; McGill University Genome Centre, McGill University, Montreal, Quebec, Canada., Pfister SM; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Pediatric Oncology, Hematology, Immunology and Pulmonology, University Hospital Heidelberg, Heidelberg, Germany., Kim SK; Department of Neurosurgery, Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Seoul, South Korea., Delattre O; SIREDO Oncology Center (Pediatric, Adolescent and Young Adults Oncology), Institut Curie, Paris, France.; INSERM U830, Institut Curie, Paris, France., Bourdeaut F; SIREDO Oncology Center (Pediatric, Adolescent and Young Adults Oncology), Institut Curie, Paris, France.; INSERM U830, Institut Curie, Paris, France., Doz F; SIREDO Oncology Center (Pediatric, Adolescent and Young Adults Oncology), Institut Curie, Paris, France.; Université Paris Cité, Paris, France., Masliah-Planchon J; Unit of Somatic Genetics, Institut Curie, Paris, France., Grajkowska WA; Department of Pathology, The Children's Memorial Health Institute, Warsaw, Poland., Loukides J; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada., Dirks P; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Division of Neurosurgery, The Hospital for Sick Children, Toronto, Ontario, Canada., Fèvre-Montange M; INSERM U1028, CNRS UMR5292, Centre de Recherche en Neurosciences, Université de Lyon, Lyon, France.; Centre de Pathologie EST, Groupement Hospitalier EST, Université de Lyon, Bron, France., Jouvet A; Centre de Pathologie EST, Groupement Hospitalier EST, Université de Lyon, Bron, France., French PJ; Department of Neurology, Erasmus University Medical Center, Rotterdam, Netherlands., Kros JM; Department of Pathology, Erasmus University Medical Center, Rotterdam, Netherlands., Zitterbart K; Department of Pediatric Oncology, Masaryk University School of Medicine, Brno, Czech Republic., Bailey SD; Department of Surgery, Division of Thoracic and Upper Gastrointestinal Surgery, Faculty of Medicine, McGill University, Montreal, Quebec, Canada.; Cancer Research Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada., Eberhart CG; Departments of Pathology, Ophthalmology and Oncology, John Hopkins University School of Medicine, Baltimore, MD, USA., Rao AAN; Division of Pediatric Hematology/Oncology, Mayo Clinic, Rochester, MN, USA., Giannini C; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA., Olson JM; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Garami M; 2nd Department of Pediatrics, Semmelweis University, Budapest, Hungary., Hauser P; 2nd Department of Pediatrics, Semmelweis University, Budapest, Hungary., Phillips JJ; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.; Department of Pathology, University of California San Francisco, San Francisco, CA, USA., Ra YS; Department of Neurosurgery, University of Ulsan, Asan Medical Center, Seoul, South Korea., de Torres C; Developmental Tumor Biology Laboratory, Hospital Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain., Mora J; Developmental Tumor Biology Laboratory, Hospital Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain., Li KKW; Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Shatin, Hong Kong., Ng HK; Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Shatin, Hong Kong., Poon WS; Department of Surgery, The Chinese University of Hong Kong, Shatin, Hong Kong., Pollack IF; Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., López-Aguilar E; Division of Pediatric Hematology/Oncology, Hospital Pediatría Centro Médico Nacional century XXI, Mexico City, Mexico., Gillespie GY; Department of Neurosurgery, University of Alabama at Birmingham, Birmingham, AL, USA., Van Meter TE; Pediatrics, Virginia Commonwealthy University, School of Medicine, Richmond, VA, USA., Shofuda T; Division of Stem Cell Research, Institute for Clinical Research, Osaka National Hospital, Osaka, Japan., Vibhakar R; Department of Pediatrics, University of Colorado Denver, Aurora, CO, USA., Thompson RC; Department of Neurological Surgery, Vanderbilt Medical Center, Nashville, TN, USA., Cooper MK; Department of Neurology, Vanderbilt Medical Center, Nashville, TN, USA., Rubin JB; Departments of Neuroscience, Washington University School of Medicine in St Louis, St Louis, MO, USA., Kumabe T; Department of Neurosurgery, Kitasato University School of Medicine, Sagamihara, Japan., Jung S; Department of Neurosurgery, Chonnam National University Research Institute of Medical Sciences, Chonnam National University Hwasun Hospital and Medical School, Hwasun-gun, South Korea., Lach B; Department of Pathology and Molecular Medicine, Division of Anatomical Pathology, McMaster University, Hamilton, Ontario, Canada.; Department of Pathology and Laboratory Medicine, Hamilton General Hospital, Hamilton, Ontario, Canada., Iolascon A; Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), University of Naples Federico II, Naples, Italy.; CEINGE Biotecnologie Avanzate, Naples, Italy., Ferrucci V; Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), University of Naples Federico II, Naples, Italy.; CEINGE Biotecnologie Avanzate, Naples, Italy., de Antonellis P; Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), University of Naples Federico II, Naples, Italy.; CEINGE Biotecnologie Avanzate, Naples, Italy., Zollo M; Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), University of Naples Federico II, Naples, Italy.; CEINGE Biotecnologie Avanzate, Naples, Italy., Cinalli G; Department of Pediatric Neurosurgery, Santobono-Pausilipon Children's Hospital, Naples, Italy., Robinson S; Division of Pediatric Neurosurgery, Case Western Reserve, Cleveland, OH, USA., Stearns DS; Department of Pediatrics-Hematology and Oncology, Case Western Reserve, Cleveland, OH, USA., Van Meir EG; Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA., Porrati P; Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy., Finocchiaro G; Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy., Massimino M; Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy., Carlotti CG; Department of Surgery and Anatomy, Faculty of Medicine of Ribeirão Preto, University of São Paulo, São Paulo, Brazil., Faria CC; Division of Neurosurgery, Centro Hospitalar Lisboa Norte (CHULN), Hospital de Santa Maria, Lisbon, Portugal.; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal., Roussel MF; Department of Tumor Cell Biology, St Jude Children's Research Hospital, Memphis, TN, USA., Boop F; Department of Tumor Cell Biology, St Jude Children's Research Hospital, Memphis, TN, USA., Chan JA; Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada., Aldinger KA; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA.; Brotman Baty Institute for Precision Medicine, Seattle, WA, USA., Razavi F; Assistance Publique Hôpitaux de Paris, Hôpital Necker-Enfants Malades, Paris, France., Silvestri E; Surgical Pathology Unit, San Camillo Forlanini Hospital, Rome, Italy., McLendon RE; Department of Pathology, Duke University, Durham, NC, USA.; Department of Neurosurgery, Duke University, Durham, NC, USA., Thompson EM; Department of Neurosurgery, Duke University, Durham, NC, USA., Ansari M; Cansearch Research Platform for Pediatric Oncology and Hematology, Faculty of Medicine, Department of Pediatrics, Gynecology and Obstetrics, University of Geneva, Geneva, Switzerland.; Division of Pediatric Oncology and Hematology, Department of Women, Child and Adolescent, University Geneva Hospitals, Geneva, Switzerland., Garre ML; U.O. Neurochirurgia, Istituto Giannina Gaslini, Genova, Italy., Chico F; Department of Neurosurgery, Hospital Infantil de Mexico Federico Gomez, Mexico City, Mexico., Eguía P; Department of Neurosurgery, Hospital Infantil de Mexico Federico Gomez, Mexico City, Mexico., Pérezpeña M; Instituto Nacional De Pediatría de México, Mexico City, Mexico., Morrissy AS; Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; Alberta Children's Hospital Research Institute, Calgary, Alberta, Canada., Cavalli FMG; INSERM U900, Institut Curie, Paris, France.; PSL Research University, Institut Curie, Paris, France.; CBIO-Centre for Computational Biology, PSL Research University, MINES ParisTech, Paris, France., Wu X; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada., Daniels C; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada., Rich JN; UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Jones SJM; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia, Canada., Moore RA; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada., Marra MA; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada., Huang X; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada., Reimand J; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Computational Biology Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Sorensen PH; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Molecular Oncology, BC Cancer Agency, Vancouver, British Columbia, Canada., Wechsler-Reya RJ; Tumor Initiation and Maintenance Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Weiss WA; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.; Department of Neurology, University of California San Francisco, San Francisco, CA, USA.; Department of Pediatrics, University of California San Francisco, San Francisco, CA, USA., Pugh TJ; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.; Computational Biology Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada., Garzia L; Cancer Research Program, McGill University Health Centre Research Institute, Montreal, Quebec, Canada., Kleinman CL; Department of Human Genetics, McGill University, Montreal, Quebec, Canada.; Lady Davis Research Institute, Jewish General Hospital, Montreal, Quebec, Canada., Stein LD; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Adaptive Oncology, Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Jabado N; Departments of Pediatrics and Human Genetics, McGill University, Montreal, Quebec, Canada.; The Research Institute of the McGill University Health Center, Montreal, Quebec, Canada., Malkin D; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.; Division of Haematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada., Ayrault O; PSL Research University, Université Paris Sud, Université Paris-Saclay, CNRS UMR 3347, INSERM U1021, Institut Curie, Orsay, France., Golden JA; Department of Pathology, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Ellison DW; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA., Doble B; Department of Pediatrics and Child Health and Department of Biochemistry and Medical Genetics, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada., Ramaswamy V; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.; Division of Haematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada., Werbowetski-Ogilvie TE; Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba, Canada.; CancerCare Manitoba Research Institute, Winnipeg, Manitoba, Canada., Suzuki H; Division of Brain Tumor Translational Research, National Cancer Center Research Institute, Tokyo, Japan., Millen KJ; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA., Taylor MD; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada. mdt.cns@gmail.com.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada. mdt.cns@gmail.com.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada. mdt.cns@gmail.com.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada. mdt.cns@gmail.com.; Division of Neurosurgery, The Hospital for Sick Children, Toronto, Ontario, Canada. mdt.cns@gmail.com.

المصدر: Nature [Nature] 2022 Dec; Vol. 612 (7940), pp. E12.

نوع المنشور: Published Erratum

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: PubMed not MEDLINE; MEDLINE

المؤلفون: Hendrikse LD; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada., Haldipur P; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA., Saulnier O; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada., Millman J; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA., Sjoboen AH; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA., Erickson AW; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Ong W; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Gordon V; Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba, Canada., Coudière-Morrison L; Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba, Canada., Mercier AL; PSL Research University, Université Paris Sud, Université Paris-Saclay, CNRS UMR 3347, INSERM U1021, Institut Curie, Orsay, France., Shokouhian M; Department of Pediatrics and Child Health and Department of Biochemistry and Medical Genetics, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada., Suárez RA; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada., Ly M; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Borlase S; Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba, Canada., Scott DS; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada., Vladoiu MC; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Farooq H; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Sirbu O; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada., Nakashima T; Division of Brain Tumor Translational Research, National Cancer Center Research Institute, Tokyo, Japan., Nambu S; Division of Brain Tumor Translational Research, National Cancer Center Research Institute, Tokyo, Japan., Funakoshi Y; Division of Brain Tumor Translational Research, National Cancer Center Research Institute, Tokyo, Japan., Bahcheli A; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Computational Biology Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Diaz-Mejia JJ; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada., Golser J; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA., Bach K; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA., Phuong-Bao T; Department of Pediatrics and Child Health and Department of Biochemistry and Medical Genetics, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada., Skowron P; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Wang EY; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada., Kumar SA; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Balin P; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Visvanathan A; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada., Lee JJY; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Ayoub R; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada., Chen X; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada., Chen X; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada., Mungall KL; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada., Luu B; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada., Bérubé P; McGill University Genome Centre, McGill University, Montreal, Quebec, Canada., Wang YC; McGill University Genome Centre, McGill University, Montreal, Quebec, Canada., Pfister SM; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Pediatric Oncology, Hematology, Immunology and Pulmonology, University Hospital Heidelberg, Heidelberg, Germany., Kim SK; Department of Neurosurgery, Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Seoul, South Korea., Delattre O; SIREDO Oncology Center (Pediatric, Adolescent and Young Adults Oncology), Institut Curie, Paris, France.; INSERM U830, Institut Curie, Paris, France., Bourdeaut F; SIREDO Oncology Center (Pediatric, Adolescent and Young Adults Oncology), Institut Curie, Paris, France.; INSERM U830, Institut Curie, Paris, France., Doz F; SIREDO Oncology Center (Pediatric, Adolescent and Young Adults Oncology), Institut Curie, Paris, France.; Université Paris Cité, Paris, France., Masliah-Planchon J; Unit of Somatic Genetics, Institut Curie, Paris, France., Grajkowska WA; Department of Pathology, The Children's Memorial Health Institute, Warsaw, Poland., Loukides J; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada., Dirks P; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Division of Neurosurgery, The Hospital for Sick Children, Toronto, Ontario, Canada., Fèvre-Montange M; INSERM U1028, CNRS UMR5292, Centre de Recherche en Neurosciences, Université de Lyon, Lyon, France.; Centre de Pathologie EST, Groupement Hospitalier EST, Université de Lyon, Bron, France., Jouvet A; Centre de Pathologie EST, Groupement Hospitalier EST, Université de Lyon, Bron, France., French PJ; Department of Neurology, Erasmus University Medical Center, Rotterdam, Netherlands., Kros JM; Department of Pathology, Erasmus University Medical Center, Rotterdam, Netherlands., Zitterbart K; Department of Pediatric Oncology, Masaryk University School of Medicine, Brno, Czech Republic., Bailey SD; Department of Surgery, Division of Thoracic and Upper Gastrointestinal Surgery, Faculty of Medicine, McGill University, Montreal, Quebec, Canada.; Cancer Research Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada., Eberhart CG; Departments of Pathology, Ophthalmology and Oncology, John Hopkins University School of Medicine, Baltimore, MD, USA., Rao AAN; Division of Pediatric Hematology/Oncology, Mayo Clinic, Rochester, MN, USA., Giannini C; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA., Olson JM; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Garami M; 2nd Department of Pediatrics, Semmelweis University, Budapest, Hungary., Hauser P; 2nd Department of Pediatrics, Semmelweis University, Budapest, Hungary., Phillips JJ; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.; Department of Pathology, University of California San Francisco, San Francisco, CA, USA., Ra YS; Department of Neurosurgery, University of Ulsan, Asan Medical Center, Seoul, South Korea., de Torres C; Developmental Tumor Biology Laboratory, Hospital Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain., Mora J; Developmental Tumor Biology Laboratory, Hospital Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain., Li KKW; Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Shatin, Hong Kong., Ng HK; Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Shatin, Hong Kong., Poon WS; Department of Surgery, The Chinese University of Hong Kong, Shatin, Hong Kong., Pollack IF; Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., López-Aguilar E; Division of Pediatric Hematology/Oncology, Hospital Pediatría Centro Médico Nacional century XXI, Mexico City, Mexico., Gillespie GY; Department of Neurosurgery, University of Alabama at Birmingham, Birmingham, AL, USA., Van Meter TE; Pediatrics, Virginia Commonwealthy University, School of Medicine, Richmond, VA, USA., Shofuda T; Division of Stem Cell Research, Institute for Clinical Research, Osaka National Hospital, Osaka, Japan., Vibhakar R; Department of Pediatrics, University of Colorado Denver, Aurora, CO, USA., Thompson RC; Department of Neurological Surgery, Vanderbilt Medical Center, Nashville, TN, USA., Cooper MK; Department of Neurology, Vanderbilt Medical Center, Nashville, TN, USA., Rubin JB; Departments of Neuroscience, Washington University School of Medicine in St Louis, St Louis, MO, USA., Kumabe T; Department of Neurosurgery, Kitasato University School of Medicine, Sagamihara, Japan., Jung S; Department of Neurosurgery, Chonnam National University Research Institute of Medical Sciences, Chonnam National University Hwasun Hospital and Medical School, Hwasun-gun, South Korea., Lach B; Department of Pathology and Molecular Medicine, Division of Anatomical Pathology, McMaster University, Hamilton, Ontario, Canada.; Department of Pathology and Laboratory Medicine, Hamilton General Hospital, Hamilton, Ontario, Canada., Iolascon A; Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), University of Naples Federico II, Naples, Italy.; CEINGE Biotecnologie Avanzate, Naples, Italy., Ferrucci V; Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), University of Naples Federico II, Naples, Italy.; CEINGE Biotecnologie Avanzate, Naples, Italy., de Antonellis P; Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), University of Naples Federico II, Naples, Italy.; CEINGE Biotecnologie Avanzate, Naples, Italy., Zollo M; Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), University of Naples Federico II, Naples, Italy.; CEINGE Biotecnologie Avanzate, Naples, Italy., Cinalli G; Department of Pediatric Neurosurgery, Santobono-Pausilipon Children's Hospital, Naples, Italy., Robinson S; Division of Pediatric Neurosurgery, Case Western Reserve, Cleveland, OH, USA., Stearns DS; Department of Pediatrics-Hematology and Oncology, Case Western Reserve, Cleveland, OH, USA., Van Meir EG; Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA., Porrati P; Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy., Finocchiaro G; Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy., Massimino M; Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy., Carlotti CG; Department of Surgery and Anatomy, Faculty of Medicine of Ribeirão Preto, University of São Paulo, São Paulo, Brazil., Faria CC; Division of Neurosurgery, Centro Hospitalar Lisboa Norte (CHULN), Hospital de Santa Maria, Lisbon, Portugal.; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal., Roussel MF; Department of Tumor Cell Biology, St Jude Children's Research Hospital, Memphis, TN, USA., Boop F; Department of Tumor Cell Biology, St Jude Children's Research Hospital, Memphis, TN, USA., Chan JA; Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada., Aldinger KA; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA.; Brotman Baty Institute for Precision Medicine, Seattle, WA, USA., Razavi F; Assistance Publique Hôpitaux de Paris, Hôpital Necker-Enfants Malades, Paris, France., Silvestri E; Surgical Pathology Unit, San Camillo Forlanini Hospital, Rome, Italy., McLendon RE; Department of Pathology, Duke University, Durham, NC, USA.; Department of Neurosurgery, Duke University, Durham, NC, USA., Thompson EM; Department of Neurosurgery, Duke University, Durham, NC, USA., Ansari M; Cansearch Research Platform for Pediatric Oncology and Hematology, Faculty of Medicine, Department of Pediatrics, Gynecology and Obstetrics, University of Geneva, Geneva, Switzerland.; Division of Pediatric Oncology and Hematology, Department of Women, Child and Adolescent, University Geneva Hospitals, Geneva, Switzerland., Garre ML; U.O. Neurochirurgia, Istituto Giannina Gaslini, Genova, Italy., Chico F; Department of Neurosurgery, Hospital Infantil de Mexico Federico Gomez, Mexico City, Mexico., Eguía P; Department of Neurosurgery, Hospital Infantil de Mexico Federico Gomez, Mexico City, Mexico., Pérezpeña M; Instituto Nacional De Pediatría de México, Mexico City, Mexico., Morrissy AS; Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; Alberta Children's Hospital Research Institute, Calgary, Alberta, Canada., Cavalli FMG; INSERM U900, Institut Curie, Paris, France.; PSL Research University, Institut Curie, Paris, France.; CBIO-Centre for Computational Biology, PSL Research University, MINES ParisTech, Paris, France., Wu X; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada., Daniels C; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada., Rich JN; UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Jones SJM; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia, Canada., Moore RA; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada., Marra MA; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada., Huang X; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada., Reimand J; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Computational Biology Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Sorensen PH; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Molecular Oncology, BC Cancer Agency, Vancouver, British Columbia, Canada., Wechsler-Reya RJ; Tumor Initiation and Maintenance Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Weiss WA; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.; Department of Neurology, University of California San Francisco, San Francisco, CA, USA.; Department of Pediatrics, University of California San Francisco, San Francisco, CA, USA., Pugh TJ; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.; Computational Biology Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada., Garzia L; Cancer Research Program, McGill University Health Centre Research Institute, Montreal, Quebec, Canada., Kleinman CL; Department of Human Genetics, McGill University, Montreal, Quebec, Canada.; Lady Davis Research Institute, Jewish General Hospital, Montreal, Quebec, Canada., Stein LD; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Adaptive Oncology, Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Jabado N; Departments of Pediatrics and Human Genetics, McGill University, Montreal, Quebec, Canada.; The Research Institute of the McGill University Health Center, Montreal, Quebec, Canada., Malkin D; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.; Division of Haematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada., Ayrault O; PSL Research University, Université Paris Sud, Université Paris-Saclay, CNRS UMR 3347, INSERM U1021, Institut Curie, Orsay, France., Golden JA; Department of Pathology, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Ellison DW; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA., Doble B; Department of Pediatrics and Child Health and Department of Biochemistry and Medical Genetics, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada., Ramaswamy V; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.; Division of Haematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada., Werbowetski-Ogilvie TE; Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba, Canada.; CancerCare Manitoba Research Institute, Winnipeg, Manitoba, Canada., Suzuki H; Division of Brain Tumor Translational Research, National Cancer Center Research Institute, Tokyo, Japan., Millen KJ; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA., Taylor MD; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada. mdt.cns@gmail.com.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada. mdt.cns@gmail.com.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada. mdt.cns@gmail.com.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada. mdt.cns@gmail.com.; Division of Neurosurgery, The Hospital for Sick Children, Toronto, Ontario, Canada. mdt.cns@gmail.com.

المصدر: Nature [Nature] 2022 Sep; Vol. 609 (7929), pp. 1021-1028. Date of Electronic Publication: 2022 Sep 21.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Cell Differentiation*/genetics , Cerebellar Neoplasms*/classification , Cerebellar Neoplasms*/genetics , Cerebellar Neoplasms*/pathology , Medulloblastoma*/classification , Medulloblastoma*/genetics , Medulloblastoma*/pathology , Metencephalon*/embryology , Metencephalon*/pathology, Cell Lineage ; Cerebellum/embryology ; Cerebellum/pathology ; Core Binding Factor alpha Subunits/genetics ; Hedgehog Proteins/metabolism ; Histone Demethylases ; Humans ; Ki-67 Antigen/metabolism ; Muscle Proteins ; Mutation ; Otx Transcription Factors/deficiency ; Otx Transcription Factors/genetics ; Repressor Proteins ; T-Box Domain Proteins/metabolism ; Transcription Factors

المؤلفون: Skowron P; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada., Farooq H; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada., Cavalli FMG; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada., Morrissy AS; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.; Alberta Children's Hospital Research Institute, Calgary, AB, Canada.; Charbonneau Cancer Institute, University of Calgary, Calgary, AB, Canada., Ly M; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada., Hendrikse LD; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada., Wang EY; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada., Djambazian H; McGill University Genome Centre, McGill University, Montreal, QC, Canada.; Department of Human Genetics, McGill University, Montreal, QC, Canada., Zhu H; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.; Computational Biology Program, Ontario Institute for Cancer Research, Toronto, ON, Canada., Mungall KL; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, BC, Canada., Trinh QM; Computational Biology Program, Ontario Institute for Cancer Research, Toronto, ON, Canada., Zheng T; Department of Neurology, University of California San Francisco, San Francisco, CA, United States., Dai S; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, United States., Stucklin ASG; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada., Vladoiu MC; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada., Fong V; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada., Holgado BL; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada., Nor C; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada., Wu X; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada., Abd-Rabbo D; Computational Biology Program, Ontario Institute for Cancer Research, Toronto, ON, Canada., Bérubé P; McGill University Genome Centre, McGill University, Montreal, QC, Canada., Wang YC; McGill University Genome Centre, McGill University, Montreal, QC, Canada., Luu B; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada., Suarez RA; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada., Rastan A; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada.; Institute of Medical Science, University of Toronto, Toronto, ON, Canada., Gillmor AH; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.; Alberta Children's Hospital Research Institute, Calgary, AB, Canada.; Charbonneau Cancer Institute, University of Calgary, Calgary, AB, Canada., Lee JJY; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada., Zhang XY; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada., Daniels C; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada., Dirks P; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada.; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada., Malkin D; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.; Division of Haematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada., Bouffet E; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada.; Division of Haematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada., Tabori U; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada.; Institute of Medical Science, University of Toronto, Toronto, ON, Canada.; Division of Haematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada., Loukides J; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada., Doz FP; SIREDO Center (pediatric, adolescent and young adults oncology), Institut Curie, University of Paris, Paris, France., Bourdeaut F; SIREDO Center (pediatric, adolescent and young adults oncology), Institut Curie, University of Paris, Paris, France., Delattre OO; INSERM U 830, Institut Curie, Paris, France., Masliah-Planchon J; Unit of Somatic Genetics, Institut Curie, Paris, France., Ayrault O; PSL Research University, Université Paris Sud, Université Paris-Saclay, CNRS UMR 3347, INSERM U1021, Institut Curie, Paris, France., Kim SK; Department of Neurosurgery, Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Seoul, South Korea., Meyronet D; Hospices Civils de Lyon, Institute of Pathology, University Lyon 1, Department of Cancer Cell Plasticity-INSERM U1052 Cancer Research Center of Lyon, Lyon, France., Grajkowska WA; Department of Pathology, The Children's Memorial Health Institute, Warsaw, Poland., Carlotti CG; Department of Surgery and Anatomy, Faculty of Medicine of Ribeirão Preto, University of Sao Paulo, São Paulo, Brazil., de Torres C; Developmental Tumor Biology Laboratory, Hospital Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain., Mora J; Developmental Tumor Biology Laboratory, Hospital Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain., Eberhart CG; Departments of Pathology, Ophthalmology and Oncology, John Hopkins University School of Medicine, Baltimore, MD, United States., Van Meir EG; Department of Hematology & Medical Oncology, School of Medicine and Winship Cancer Institute, Emory University, Atlanta, GA, United States., Kumabe T; Department of Neurosurgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan., French PJ; Department of Neurology, Erasmus University Medical Center, Rotterdam, Netherlands., Kros JM; Department of Pathology, Erasmus University Medical Center, Rotterdam, Netherlands., Jabado N; Division of Experimental Medicine, McGill University, Montreal, QC, Canada., Lach B; Department of Pathology and Molecular Medicine, Division of Anatomical Pathology, McMaster University, Hamilton, ON, Canada.; Department of Pathology and Laboratory Medicine, Hamilton General Hospital, Hamilton, ON, Canada., Pollack IF; Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States., Hamilton RL; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States., Rao AAN; Division of Pediatric Hematology/Oncology, Mayo Clinic, Rochester, MN, United States., Giannini C; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, United States., Olson JM; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, United States., Bognár L; Department of Neurosurgery, University of Debrecen, Medical and Health Science Centre, Debrecen, Hungary., Klekner A; Department of Neurosurgery, University of Debrecen, Medical and Health Science Centre, Debrecen, Hungary., Zitterbart K; Department of Pediatric Oncology, Masaryk University School of Medicine, Brno, Czech Republic., Phillips JJ; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, United States.; Department of Pathology, University of California San Francisco, San Francisco, CA, United States., Thompson RC; Department of Neurological Surgery, Vanderbilt Medical Center, Nashville, TN, United States., Cooper MK; Department of Neurology, Vanderbilt Medical Center, Nashville, TN, United States., Rubin JB; Departments of Neuroscience, Washington University School of Medicine in St. Louis, St. Louis, MO, United States., Liau LM; Department of Neurosurgery, David Geffen School of Medicine at UCLA, Los Angeles, California, United States., Garami M; 2nd Department of Pediatrics, Semmelweis University, Budapest, Hungary., Hauser P; 2nd Department of Pediatrics, Semmelweis University, Budapest, Hungary., Li KKW; Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong., Ng HK; Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong., Poon WS; Department of Surgery, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong., Yancey Gillespie G; Department of Neurosurgery, University of Alabama at Birmingham, Birmingham, AL, United States., Chan JA; Charbonneau Cancer Institute, University of Calgary, Calgary, AB, Canada., Jung S; Department of Neurosurgery, Chonnam National University Research Institute of Medical Sciences, Chonnam National University Hwasun Hospital and Medical School, Hwasun-gun, Jeollanam-do, South Korea., McLendon RE; Department of Pathology, Duke University, Durham, NC, United States.; Department of Neurosurgery, Duke University, Durham, NC, United States., Thompson EM; Department of Neurosurgery, Duke University, Durham, NC, United States., Zagzag D; Department of Pathology and Neurosurgery, NYU Grossman School of Medicine and NYU Langone Health, New York, NY, United States., Vibhakar R; Department of Pediatrics, University of Colorado Denver, Aurora, CO, United States., Ra YS; Department of Neurosurgery, University of Ulsan, Asan Medical Center, Seoul, South Korea., Garre ML; U.O. Neurochirurgia, Istituto Giannina Gaslini, Genova, Italy., Schüller U; Institute of Neuropathology, University Medical Center, Hamburg-Eppendorf, Germany.; Research Institute Children's Cancer Center, Hamburg, Germany.; Pediatric Hematology and Oncology, University Medical Center, Hamburg-Eppendorf, Germany., Shofuda T; Division of Stem Cell Research, Institute for Clinical Research, Osaka National Hospital, Osaka, Japan., Faria CC; Division of Neurosurgery, Centro Hospitalar Lisboa Norte (CHULN), Hospital de Santa Maria, Lisbon, Portugal.; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal., López-Aguilar E; Division of Pediatric Hematology/Oncology, Hospital Pediatría Centro Médico Nacional century XXI, Mexico City, Mexico., Zadeh G; Division of Neurosurgery, Toronto Western Hospital, University Health Network, Toronto, ON, Canada.; MacFeeters-Hamilton Center for Neuro-Oncology Research, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Hui CC; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada., Ramaswamy V; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.; Division of Haematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada., Bailey SD; Department of Surgery, Division of Thoracic and Upper Gastrointestinal Surgery, Faculty of Medicine, McGill University, Montreal, QC, Canada.; Cancer Research Program, Research Institute of the McGill University Health Centre, Montreal, QC, Canada., Jones SJ; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, BC, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada.; Department of Molecular Biology & Biochemistry, Simon Fraser University, Burnaby, BC, Canada., Mungall AJ; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, BC, Canada., Moore RA; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, BC, Canada., Calarco JA; Department of Cell & Systems Biology, University of Toronto, Toronto, ON, Canada., Stein LD; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.; Adaptive Oncology, Ontario Institute for Cancer Research, Toronto, ON, Canada., Bader GD; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.; The Donnelly Centre, University of Toronto, Toronto, ON, Canada., Reimand J; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.; Computational Biology Program, Ontario Institute for Cancer Research, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada., Ragoussis J; McGill University Genome Centre, McGill University, Montreal, QC, Canada.; Department of Human Genetics, McGill University, Montreal, QC, Canada., Weiss WA; Department of Neurology, University of California San Francisco, San Francisco, CA, United States.; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, United States.; Department of Pediatrics, University of California San Francisco, San Francisco, CA, United States., Marra MA; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, BC, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada., Suzuki H; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada. hisuzuki-ngy@umin.ac.jp.; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada. hisuzuki-ngy@umin.ac.jp., Taylor MD; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada. mdt.cns@gmail.com.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada. mdt.cns@gmail.com.; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada. mdt.cns@gmail.com.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada. mdt.cns@gmail.com.; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON, Canada. mdt.cns@gmail.com.; Department of Surgery, University of Toronto, Toronto, ON, Canada. mdt.cns@gmail.com.

المصدر: Nature communications [Nat Commun] 2021 Mar 19; Vol. 12 (1), pp. 1749. Date of Electronic Publication: 2021 Mar 19.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Regulation, Neoplastic* , Transcriptome*, Cerebellar Neoplasms/*genetics , Hedgehog Proteins/*genetics , Medulloblastoma/*genetics, Adolescent ; Adult ; Child ; Child, Preschool ; Female ; Gene Regulatory Networks ; Genetic Variation ; Humans ; Infant ; Male ; Middle Aged ; Signal Transduction/genetics ; Young Adult

المؤلفون: Cavalli FMG; Programme in Developmental and Stem Cell Biology, The Hospital for Sick Children, Toronto, ON, Canada., Hübner JM; Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany., Sharma T; Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany., Luu B; Programme in Developmental and Stem Cell Biology, The Hospital for Sick Children, Toronto, ON, Canada., Sill M; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany., Zapotocky M; Division of Haematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, 555 University Ave, Toronto, ON, M5G 1X8, Canada., Mack SC; Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA., Witt H; Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.; Department of Pediatric Hematology and Oncology, University Hospital Heidelberg, Heidelberg, Germany., Lin T; Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN, USA., Shih DJH; Department of Biostatistics and Computational Biology, Dana Farber Cancer Center, Harvard Medical School, Boston, MA, USA., Ho B; Division of Haematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, 555 University Ave, Toronto, ON, M5G 1X8, Canada., Santi M; Department of Pathology, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Emery L; Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA., Hukin J; Division of Oncology and Neurology, British Columbia Children's Hospital, Vancouver, BC, Canada., Dunham C; Department of Pathology, British Columbia Children's Hospital, Vancouver, BC, Canada., McLendon RE; The Preston Robert Tisch Brain Tumor Center, Duke University, Durham, NC, USA., Lipp ES; The Preston Robert Tisch Brain Tumor Center, Duke University, Durham, NC, USA., Gururangan S; Department of Neurosurgery, Preston A. Wells Center for Brain Tumor Therapy, McKnight Brain Institute, University of Florida, Gainsville, FL, USA., Grossbach A; Department of Neurosurgery, University of Iowa Hospitals and Clinics, Iowa City, IA, USA., French P; Erasmus University Medical Center, Rotterdam, The Netherlands., Kros JM; Erasmus University Medical Center, Rotterdam, The Netherlands., van Veelen MC; Erasmus University Medical Center, Rotterdam, The Netherlands., Rao AAN; Division of Pediatric Hematology/Oncology, Mayo Clinic, Rochester, MN, USA., Giannini C; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA., Leary S; Cancer and Blood Disorders Center, Seattle Children's Hospital, Seattle, WA, USA., Jung S; Department of Neurosurgery, Chonnam National University Research Institute of Medical Sciences, Chonnam National University Hwasun Hospital and Medical School, Hwasun-gun, Chonnam, South Korea., Faria CC; Division of Neurosurgery, Centro Hospitalar Lisboa Norte, Hospital de Santa Maria, Lisbon, Portugal., Mora J; Developmental Tumor Biology Laboratory, Hospital Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain., Schüller U; Pediatric Hematology and Oncology, Institute of Neuropathology, University Medical Center, Research Institute Children's Cancer Center, Hamburg-Eppendorf, Germany., Alonso MM; Program in Solid Tumors and Biomarkers, Department of Pediatrics, The Health Research Institute of Navarra (IDISNA), Foundation for the Applied Medical Research, Clínica Universidad de Navarra, University of Navarra, Pamplona, Navarra, Spain., Chan JA; Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, AB, Canada., Klekner A; Department of Neurosurgery, Medical and Health Science Centre, University of Debrecen, Debrecen, Hungary., Chambless LB; Department of Neurological Surgery, Vanderbilt Medical Center, Nashville, TN, USA., Hwang EI; Center for Cancer and Blood Disorders, Children's National Medical Center, Washington DC, USA., Massimino M; Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy., Eberhart CG; Departments of Pathology, Ophthalmology and Oncology, John Hopkins University School of Medicine, Baltimore, MD, USA., Karajannis MA; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Lu B; Division of Pediatric Hematology/Oncology, NYU Langone Medical Center, New York, NY, USA., Liau LM; Department of Neurosurgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Zollo M; Dipartimento di Biochimica e Biotecnologie Mediche, University of Naples, Naples, Italy., Ferrucci V; Dipartimento di Biochimica e Biotecnologie Mediche, University of Naples, Naples, Italy., Carlotti C; Department of Surgery and Anatomy, Faculty of Medicine of Ribeirão Preto, University of Sao Paulo, São Paulo, Brazil., Tirapelli DPC; Department of Surgery and Anatomy, Faculty of Medicine of Ribeirão Preto, University of Sao Paulo, São Paulo, Brazil., Tabori U; Division of Haematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, 555 University Ave, Toronto, ON, M5G 1X8, Canada., Bouffet E; Division of Haematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, 555 University Ave, Toronto, ON, M5G 1X8, Canada., Ryzhova M; Department of Neuropathology, NN Burdenko Neurosurgical Institute, 125047, Moscow, Russia., Ellison DW; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA., Merchant TE; Department of Radiation Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA., Gilbert MR; Neuro-Oncology Branch, National Cancer Institute, Bethesda, MD, USA., Armstrong TS; Neuro-Oncology Branch, National Cancer Institute, Bethesda, MD, USA., Korshunov A; Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Pfister SM; Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.; Department of Pediatric Hematology and Oncology, University Hospital Heidelberg, Heidelberg, Germany., Taylor MD; Programme in Developmental and Stem Cell Biology, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., Aldape K; Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA., Pajtler KW; Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.; Department of Pediatric Hematology and Oncology, University Hospital Heidelberg, Heidelberg, Germany., Kool M; Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany. m.kool@dkfz.de.; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany. m.kool@dkfz.de., Ramaswamy V; Programme in Developmental and Stem Cell Biology, The Hospital for Sick Children, Toronto, ON, Canada. vijay.ramaswamy@sickkids.ca.; Division of Haematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, 555 University Ave, Toronto, ON, M5G 1X8, Canada. vijay.ramaswamy@sickkids.ca.

المصدر: Acta neuropathologica [Acta Neuropathol] 2018 Aug; Vol. 136 (2), pp. 227-237. Date of Electronic Publication: 2018 Jul 17.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE

مواضيع طبية MeSH: DNA Copy Number Variations/*genetics , Ependymoma/*classification , Ependymoma/*genetics , Infratentorial Neoplasms/*classification , Infratentorial Neoplasms/*genetics, Adolescent ; Adult ; Age Factors ; Child ; Cohort Studies ; DNA Methylation/genetics ; Ependymoma/pathology ; Ependymoma/surgery ; Female ; Gene Expression Profiling ; Humans ; Infratentorial Neoplasms/pathology ; Infratentorial Neoplasms/surgery ; Kaplan-Meier Estimate ; Male ; Microarray Analysis ; Middle Aged ; Young Adult

المؤلفون: Thompson EM; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON, Canada; Department of Neurosurgery, Duke University, Durham, NC, USA., Hielscher T; Division of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany., Bouffet E; Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada., Remke M; Department of Pediatric Oncology, Hematology, and Clinical Immunology, University Hospital Düsseldorf, Düsseldorf, Germany., Luu B; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada., Gururangan S; The Preston Robert Tisch Brain Tumor Center, Duke University, Durham, NC, USA., McLendon RE; Department of Pathology, Duke University, Durham, NC, USA., Bigner DD; Department of Pathology, Duke University, Durham, NC, USA; The Preston Robert Tisch Brain Tumor Center, Duke University, Durham, NC, USA., Lipp ES; Department of Pathology, Duke University, Durham, NC, USA., Perreault S; Division of Child Neurology, CHU Sainte-Justine, Montreal, QC, Canada., Cho YJ; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA; Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA., Grant G; Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA; Department of Neurosurgery, Lucille Packard Children's Hospital, Stanford, CA, USA., Kim SK; Department of Neurosurgery, Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Seoul, South Korea., Lee JY; Department of Neurosurgery, Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Seoul, South Korea., Rao AAN; Division of Pediatric Hematology/Oncology, Mayo Clinic, Rochester, MN, USA., Giannini C; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA., Li KKW; Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong Special Administrative Region, China., Ng HK; Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong Special Administrative Region, China., Yao Y; Department of Neurosurgery, Hua Shan Hospital, Fudan University, Shanghai, China., Kumabe T; Department of Neurosurgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan., Tominaga T; Department of Neurosurgery, Tohoku University Graduate School of Medicine, Sendai, Japan., Grajkowska WA; Department of Pathology, The Children's Memorial Health Institute, Warsaw, Poland., Perek-Polnik M; Department of Oncology, The Children's Memorial Health Institute, Warsaw, Poland., Low DCY; Neurosurgical Service, KK Women's and Children's Hospital, Singapore, Singapore., Seow WT; Neurosurgical Service, KK Women's and Children's Hospital, Singapore, Singapore., Chang KTE; Department of Pathology & Laboratory Medicine, KK Women's and Children's Hospital, Singapore, Singapore., Mora J; Developmental Tumor Biology Laboratory, Hospital Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain., Pollack IF; Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Hamilton RL; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Leary S; Cancer and Blood Disorders Center, Seattle Children's Hospital, Seattle, WA, USA., Moore AS; UQ Child Health Research Centre, University of Queensland, Brisbane, QLD, Australia; Oncology Service, Lady Cilento Children's Hospital, Children's Health Queensland, Brisbane, QLD, Australia., Ingram WJ; UQ Child Health Research Centre, University of Queensland, Brisbane, QLD, Australia., Hallahan AR; UQ Child Health Research Centre, University of Queensland, Brisbane, QLD, Australia; Oncology Service, Lady Cilento Children's Hospital, Children's Health Queensland, Brisbane, QLD, Australia., Jouvet A; Centre de Pathologie EST, Groupement Hospitalier EST, Université de Lyon, Lyon, France., Fèvre-Montange M; INSERM U1028, CNRS UMR5292, Centre de Recherche en Neurosciences, Université de Lyon, Lyon, France., Vasiljevic A; Centre de Pathologie et Neuropathologie Est, Centre de Biologie et Pathologie Est, Groupement Hospitalier Est, Hospices Civils de Lyon, Bron; ONCOFLAM, Neuro-Oncologie et Neuro-Inflammation Centre de Recherche en Neurosciences de Lyon, Lyon, France., Faure-Conter C; Institute of Pediatric Hematology and Oncology, Lyon, France., Shofuda T; Division of Stem Cell Research, Institute for Clinical Research, Osaka National Hospital, Osaka, Japan., Kagawa N; Department of Neurosurgery, Osaka University Graduate School of Medicine, Osaka, Japan., Hashimoto N; Department of Neurosurgery, Osaka University Graduate School of Medicine, Osaka, Japan., Jabado N; Division of Hematology/Oncology, McGill University, Montreal, QC, Canada., Weil AG; Departments of Pediatrics and Human Genetics, McGill University, Montreal, QC, Canada., Gayden T; Departments of Pediatrics and Human Genetics, McGill University, Montreal, QC, Canada., Wataya T; Department of Pediatric Neurosurgery, Shizuoka Children's Hospital, Shizuoka, Japan., Shalaby T; Departments of Oncology and Neuro-Oncology, University Children's Hospital of Zurich, Zurich, Switzerland., Grotzer M; Departments of Oncology and Neuro-Oncology, University Children's Hospital of Zurich, Zurich, Switzerland., Zitterbart K; Department of Pediatric Oncology, School of Medicine, Masaryk University, Brno, Czech Republic., Sterba J; Department of Pediatric Oncology, School of Medicine, Masaryk University, Brno, Czech Republic., Kren L; Department of Pathology, University Hospital Brno, Brno, Czech Republic., Hortobágyi T; Division of Neuropathology, University of Debrecen, Medical and Health Science Centre, Debrecen, Hungary., Klekner A; Division of Neuropathology, University of Debrecen, Medical and Health Science Centre, Debrecen, Hungary., László B; Division of Neuropathology, University of Debrecen, Medical and Health Science Centre, Debrecen, Hungary., Pócza T; 2nd Department of Pediatrics, Semmelweis University, Budapest, Hungary., Hauser P; 2nd Department of Pediatrics, Semmelweis University, Budapest, Hungary., Schüller U; Center for Neuropathology, Ludwig-Maximilians-Universität, Munich, Germany., Jung S; Department of Neurosurgery, Chonnam National University Research Institute of Medical Sciences, Chonnam National University Hwasun Hospital and Medical School, Hwasun-gun, Chonnam South Korea., Jang WY; Department of Neurosurgery, Chonnam National University Research Institute of Medical Sciences, Chonnam National University Hwasun Hospital and Medical School, Hwasun-gun, Chonnam South Korea., French PJ; Department of Neurosurgery, Erasmus University Medical Center, Rotterdam, Netherlands., Kros JM; Department of Pathology, Erasmus University Medical Center, Rotterdam, Netherlands., van Veelen MC; Department of Neurosurgery, Erasmus University Medical Center, Rotterdam, Netherlands., Massimi L; Pediatric Neurosurgery, Catholic University Medical School, Rome, Italy., Leonard JR; Department of Neurosurgery, Division of Pediatric Neurosurgery, Washington University School of Medicine and St Louis Children's Hospital, St Louis, MO, USA., Rubin JB; Departments of Pediatrics, Anatomy and Neurobiology, Washington University School of Medicine and St Louis Children's Hospital, St Louis, MO, USA., Vibhakar R; Department of Pediatrics, University of Colorado Denver, Aurora, CO, USA., Chambless LB; Department of Neurological Surgery, Vanderbilt Medical Center, Nashville, TN, USA., Cooper MK; Department of Neurology, Vanderbilt Medical Center, Nashville, TN, USA., Thompson RC; Department of Neurological Surgery, Vanderbilt Medical Center, Nashville, TN, USA., Faria CC; Division of Neurosurgery, Centro Hospitalar Lisboa Norte, Hospital de Santa Maria, Lisbon, Portugal., Carvalho A; Departamento de Oncologia Pediátrica, Hospital Pediátrico de Coimbra, Centro Hospitalar de Coimbra, Coimbra, Portugal., Nunes S; Unidade de Neuro-Oncologia Pediátrica, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal., Pimentel J; Divison of Pathology, Centro Hospitalar Lisboa Norte, Hospital de Santa Maria, Lisbon, Portugal., Fan X; Department of Neurosurgery and Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI, USA., Muraszko KM; Department of Neurosurgery, University of Michigan Medical School, Ann Arbor, MI, USA., López-Aguilar E; Division of Pediatric Hematology/Oncology, Hospital Pediatría Centro Médico Nacional Century XXI, Mexico City, Mexico., Lyden D; Department of Pediatrics and Cell and Developmental Biology, Weill Cornell Medical College, New York, NY, USA., Garzia L; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada., Shih DJH; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., Kijima N; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada., Schneider C; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON, Canada., Adamski J; Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada., Northcott PA; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Kool M; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Jones DTW; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Chan JA; Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, AB, Canada., Nikolic A; Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, AB, Canada., Garre ML; UO Neurochirurgia, Istituto Giannina Gaslini, Genova, Italy., Van Meir EG; Department of Hematology & Medical Oncology, School of Medicine and Winship Cancer Institute, Emory University, Atlanta, GA, USA., Osuka S; Department of Hematology & Medical Oncology, School of Medicine and Winship Cancer Institute, Emory University, Atlanta, GA, USA., Olson JJ; Department of Neurosurgery, School of Medicine and Winship Cancer Institute, Emory University, Atlanta, GA, USA., Jahangiri A; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA., Castro BA; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA., Gupta N; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA; Department of Pediatrics, University of California San Francisco, San Francisco, CA, USA., Weiss WA; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA; Department of Pediatrics, University of California San Francisco, San Francisco, CA, USA; Department of Neurology, University of California San Francisco, San Francisco, CA, USA., Moxon-Emre I; Program in Neuroscience and Mental Health and Department of Psychology, The Hospital for Sick Children, Toronto, ON, Canada., Mabbott DJ; Program in Neuroscience and Mental Health and Department of Psychology, The Hospital for Sick Children, Toronto, ON, Canada., Lassaletta A; Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada., Hawkins CE; Division of Pathology, The Hospital for Sick Children, Toronto, ON, Canada., Tabori U; Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada., Drake J; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON, Canada., Kulkarni A; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON, Canada., Dirks P; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON, Canada; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada., Rutka JT; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON, Canada; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., Korshunov A; Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Pfister SM; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany; Department of Pediatric Oncology, University Hospital Heidelberg, Heidelberg, Germany., Packer RJ; Department of Neurology, Children's National Medical Center, Washington, DC, USA., Ramaswamy V; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON, Canada; Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., Taylor MD; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON, Canada; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada. Electronic address: mdtaylor@sickkids.ca.

المصدر: The Lancet. Oncology [Lancet Oncol] 2016 Apr; Vol. 17 (4), pp. 484-495. Date of Electronic Publication: 2016 Mar 12.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Lancet Pub. Group Country of Publication: England NLM ID: 100957246 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-5488 (Electronic) Linking ISSN: 14702045 NLM ISO Abbreviation: Lancet Oncol Subsets: MEDLINE

مواضيع طبية MeSH: Prognosis*, Brain Neoplasms/*classification , Brain Neoplasms/*surgery , Medulloblastoma/*classification , Medulloblastoma/*surgery, Adult ; Brain Neoplasms/genetics ; Brain Neoplasms/pathology ; Canada ; Child ; Child, Preschool ; Combined Modality Therapy ; Disease Progression ; Disease-Free Survival ; Female ; Humans ; Infant ; Magnetic Resonance Imaging ; Male ; Medulloblastoma/genetics ; Medulloblastoma/pathology ; Retrospective Studies