المؤلفون: Rapado LN; LaBTryps, Instituto de Ciencias Biomedicas II, Universidade de São Paulo, Av. Lineu Prestes 1374, Cidade Universitária Butanta, São Paulo, CEP 05508-900, Brazil., Nascimento JF; LaBTryps, Instituto de Ciencias Biomedicas II, Universidade de São Paulo, Av. Lineu Prestes 1374, Cidade Universitária Butanta, São Paulo, CEP 05508-900, Brazil., Manchola NC; LaBTryps, Instituto de Ciencias Biomedicas II, Universidade de São Paulo, Av. Lineu Prestes 1374, Cidade Universitária Butanta, São Paulo, CEP 05508-900, Brazil., Damasceno FS; LaBTryps, Instituto de Ciencias Biomedicas II, Universidade de São Paulo, Av. Lineu Prestes 1374, Cidade Universitária Butanta, São Paulo, CEP 05508-900, Brazil., Achjian RW; LaBTryps, Instituto de Ciencias Biomedicas II, Universidade de São Paulo, Av. Lineu Prestes 1374, Cidade Universitária Butanta, São Paulo, CEP 05508-900, Brazil., Silber AM; LaBTryps, Instituto de Ciencias Biomedicas II, Universidade de São Paulo, Av. Lineu Prestes 1374, Cidade Universitária Butanta, São Paulo, CEP 05508-900, Brazil. Electronic address: asilber@usp.br.

المصدر: Experimental parasitology [Exp Parasitol] 2023 Dec; Vol. 255, pp. 108642. Date of Electronic Publication: 2023 Nov 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 0370713 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2449 (Electronic) Linking ISSN: 00144894 NLM ISO Abbreviation: Exp Parasitol Subsets: MEDLINE

مواضيع طبية MeSH: Trypanosoma cruzi* , Chagas Disease*/parasitology, Animals ; Amino Acids, Branched-Chain/metabolism ; Leucine ; Protozoan Proteins/metabolism ; Life Cycle Stages

المؤلفون: Santos Souza HF; Laboratory of Biochemistry of Tryps-LaBTryps, Departamento de Parasitologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil., Rocha SC; Laboratory of Biochemistry of Tryps-LaBTryps, Departamento de Parasitologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil., Damasceno FS; Laboratory of Biochemistry of Tryps-LaBTryps, Departamento de Parasitologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil., Rapado LN; Laboratory of Biochemistry of Tryps-LaBTryps, Departamento de Parasitologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil., Pral EMF; Laboratory of Biochemistry of Tryps-LaBTryps, Departamento de Parasitologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil., Marinho CRF; Laboratory of Experimental Immunoparasitology, Departamento de Parasitologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil., Silber AM; Laboratory of Biochemistry of Tryps-LaBTryps, Departamento de Parasitologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil.

المصدر: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2019 Sep 19; Vol. 13 (9), pp. e0007226. Date of Electronic Publication: 2019 Sep 19 (Print Publication: 2019).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE

مواضيع طبية MeSH: Chagas Disease/*drug therapy , Memantine/*pharmacology , Trypanocidal Agents/*pharmacology , Trypanosoma cruzi/*drug effects, Animals ; Calcium/metabolism ; Chagas Disease/parasitology ; Female ; Heart/parasitology ; Lipopolysaccharides/pharmacology ; Macrophages/parasitology ; Memantine/administration & dosage ; Mice ; Mice, Inbred BALB C ; Nitrogen Oxides/metabolism ; Parasite Load ; Parasitemia ; RAW 264.7 Cells ; Receptors, N-Methyl-D-Aspartate/antagonists & inhibitors ; Trypanocidal Agents/administration & dosage

المؤلفون: Barisón MJ; From the Laboratory of Biochemistry of Tryps-LaBTryps, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, 05508-000 São Paulo, Brazil., Rapado LN; From the Laboratory of Biochemistry of Tryps-LaBTryps, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, 05508-000 São Paulo, Brazil., Merino EF; the Department of Biochemistry and Virginia Tech Center for Drug Discovery, Virginia Tech, Blacksburg, Virginia 24061, and., Furusho Pral EM; From the Laboratory of Biochemistry of Tryps-LaBTryps, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, 05508-000 São Paulo, Brazil., Mantilla BS; From the Laboratory of Biochemistry of Tryps-LaBTryps, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, 05508-000 São Paulo, Brazil., Marchese L; From the Laboratory of Biochemistry of Tryps-LaBTryps, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, 05508-000 São Paulo, Brazil., Nowicki C; the Facultad de Farmacia y Bioquímica, Instituto de Química y Fisicoquímica Biológica (IQUIFIB-CONICET), Universidad de Buenos Aires, 1113 Buenos Aires, Argentina., Silber AM; From the Laboratory of Biochemistry of Tryps-LaBTryps, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, 05508-000 São Paulo, Brazil, asilber@usp.br., Cassera MB; the Department of Biochemistry and Virginia Tech Center for Drug Discovery, Virginia Tech, Blacksburg, Virginia 24061, and maria.cassera@uga.edu.

المصدر: The Journal of biological chemistry [J Biol Chem] 2017 May 26; Vol. 292 (21), pp. 8964-8977. Date of Electronic Publication: 2017 Mar 29.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Metabolome/*physiology , Trypanosoma cruzi/*growth & development, Life Cycle Stages/physiology ; Metabolomics

المؤلفون: Vital DG; a Department of Pharmacy , University of Sao Paulo , Sao Paulo , Brazil., Damasceno FS; b Laboratory of Biochemistry of Tryps - LaBTryps - Department of Parasitology, Institute of Biomedical Sciences , University of Sao Paulo , Sao Paulo , Brazil., Rapado LN; b Laboratory of Biochemistry of Tryps - LaBTryps - Department of Parasitology, Institute of Biomedical Sciences , University of Sao Paulo , Sao Paulo , Brazil., Silber AM; b Laboratory of Biochemistry of Tryps - LaBTryps - Department of Parasitology, Institute of Biomedical Sciences , University of Sao Paulo , Sao Paulo , Brazil., Vilella FS; c Department of Biochemistry and Immunology , University of Minas Gerais , Belo Horizonte , Minas Gerais , Brazil., Ferreira RS; c Department of Biochemistry and Immunology , University of Minas Gerais , Belo Horizonte , Minas Gerais , Brazil., Maltarollo VG; a Department of Pharmacy , University of Sao Paulo , Sao Paulo , Brazil., Trossini GH; a Department of Pharmacy , University of Sao Paulo , Sao Paulo , Brazil.

المصدر: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2017 May; Vol. 35 (6), pp. 1244-1259. Date of Electronic Publication: 2016 Jul 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: England NLM ID: 8404176 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-0254 (Electronic) Linking ISSN: 07391102 NLM ISO Abbreviation: J Biomol Struct Dyn Subsets: MEDLINE

مواضيع طبية MeSH: Drug Design*, Cysteine Endopeptidases/*chemistry , Protozoan Proteins/*chemistry , Semicarbazones/*chemistry , Trypanocidal Agents/*chemistry, Animals ; Binding Sites ; CHO Cells ; Catalytic Domain ; Cell Survival/drug effects ; Cricetulus ; Isomerism ; Magnetic Resonance Spectroscopy ; Molecular Conformation ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Molecular Structure ; Protein Binding ; Protozoan Proteins/antagonists & inhibitors ; Semicarbazones/pharmacology ; Trypanocidal Agents/pharmacology

المؤلفون: Manchola NC; LaBTryps, Instituto de Ciencias Biomedicas II, Universidade de São Paulo, Av. Lineu Prestes 1374, Cidade Universitária Butanta, São Paulo, CEP 05508-900, Brazil., Rapado LN; LaBTryps, Instituto de Ciencias Biomedicas II, Universidade de São Paulo, Av. Lineu Prestes 1374, Cidade Universitária Butanta, São Paulo, CEP 05508-900, Brazil., Barisón MJ; LaBTryps, Instituto de Ciencias Biomedicas II, Universidade de São Paulo, Av. Lineu Prestes 1374, Cidade Universitária Butanta, São Paulo, CEP 05508-900, Brazil., Silber AM; LaBTryps, Instituto de Ciencias Biomedicas II, Universidade de São Paulo, Av. Lineu Prestes 1374, Cidade Universitária Butanta, São Paulo, CEP 05508-900, Brazil.

المصدر: The Journal of eukaryotic microbiology [J Eukaryot Microbiol] 2016 May; Vol. 63 (3), pp. 299-308. Date of Electronic Publication: 2015 Nov 13.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 9306405 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1550-7408 (Electronic) Linking ISSN: 10665234 NLM ISO Abbreviation: J Eukaryot Microbiol Subsets: MEDLINE

مواضيع طبية MeSH: Amino Acids, Branched-Chain/*chemistry , Amino Acids, Branched-Chain/*metabolism , Cell Membrane/*metabolism , Trypanosoma cruzi/*metabolism, Adenosine Triphosphate/metabolism ; Amino Acid Transport Systems ; Animals ; Chagas Disease/parasitology ; Isoleucine/metabolism ; Isoleucine/pharmacology ; Kinetics ; Leucine/metabolism ; Leucine/pharmacology ; Temperature ; Trypanosoma cruzi/drug effects ; Valine/metabolism ; Valine/pharmacology

المؤلفون: Rapado LN; Laboratório de Parasitologia, Instituto Butantan, Av. Vital Brasil, 1500, São Paulo, SP, CEP 05503-900, Brazil. ludmilanr@usp.br., Freitas GC; Research Support Center in Diversity of Natural Products, Instituto de Química, Universidade de São Paulo, Av. Prof. Lineu Prestes, 748, sala 1124, São Paulo, SP, CEP 05508-000, Brazil. giovanacf@gmail.com., Polpo A; Departamento de Estatística, Centro de Ciências Exatas e de Tecnologia, Universidade Federal de São Carlos, Via Washington Luís, km 235, Sao Carlos, SP, Caixa-postal 676, CEP 13565-905, Brazil. polpo@ufscar.br., Rojas-Cardozo M; Department of Pharmacy, Faculty of Sciences, Universidad Nacional de Colombia, Kr 30 45-03, Bogotá, Colombia., Rincón JV; Department of Pharmacy, Faculty of Sciences, Universidad Nacional de Colombia, Kr 30 45-03, Bogotá, Colombia. jrinconv@unal.edu.co., Scotti MT; Centro de Ciências Aplicadas e Educação, Universidade Federal da Paraíba, Campus IV, Rua da Mangueira, s/n, Rio Tinto, PB, CEP 5829-7000, Brazil. mtscotti@gmail.com., Kato MJ; Research Support Center in Diversity of Natural Products, Instituto de Química, Universidade de São Paulo, Av. Prof. Lineu Prestes, 748, sala 1124, São Paulo, SP, CEP 05508-000, Brazil. majokato@iq.usp.br., Nakano E; Laboratório de Parasitologia, Instituto Butantan, Av. Vital Brasil, 1500, São Paulo, SP, CEP 05503-900, Brazil. eliananakano@butantan.gov.br., Yamaguchi LF; Research Support Center in Diversity of Natural Products, Instituto de Química, Universidade de São Paulo, Av. Prof. Lineu Prestes, 748, sala 1124, São Paulo, SP, CEP 05508-000, Brazil.

المصدر: Molecules (Basel, Switzerland) [Molecules] 2014 Apr 23; Vol. 19 (4), pp. 5205-18. Date of Electronic Publication: 2014 Apr 23.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

مواضيع طبية MeSH: Antiparasitic Agents/*chemistry , Benzoic Acid/*chemistry , Chalcones/*chemistry , Life Cycle Stages/*drug effects , Piper/*chemistry , Plant Extracts/*chemistry , Snails/*drug effects, Animals ; Antiparasitic Agents/isolation & purification ; Antiparasitic Agents/pharmacology ; Biological Products/chemistry ; Chalcones/isolation & purification ; Chalcones/pharmacology ; Disease Reservoirs ; Humans ; Inhibitory Concentration 50 ; Molecular Docking Simulation ; Plant Extracts/isolation & purification ; Plant Extracts/pharmacology ; Plant Leaves/chemistry ; Schistosoma mansoni/physiology ; Schistosomiasis/prevention & control ; Schistosomiasis/transmission ; Snails/growth & development ; Structure-Activity Relationship

المؤلفون: Rapado LN; Instituto de Ciências Biomédicas, Universidade de São Paulo, São PauloSP, Brazil, ludmilanr@usp.br, ludmilanr@usp.br., Lopes PO, Yamaguchi LF, Nakano E

المصدر: Revista do Instituto de Medicina Tropical de Sao Paulo [Rev Inst Med Trop Sao Paulo] 2013 Nov-Dec; Vol. 55 (6), pp. 421-4.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Universidade de São Paulo, Instituto de Medicina Tropical de São Paulo Country of Publication: Brazil NLM ID: 7507484 Publication Model: Print Cited Medium: Internet ISSN: 1678-9946 (Electronic) Linking ISSN: 00364665 NLM ISO Abbreviation: Rev Inst Med Trop Sao Paulo Subsets: MEDLINE

مواضيع طبية MeSH: Disease Vectors*, Biomphalaria/*drug effects , Molluscacides/*pharmacology , Piperaceae/*chemistry , Plant Extracts/*pharmacology, Animals ; Biomphalaria/parasitology ; Molluscacides/isolation & purification ; Piperaceae/classification ; Schistosomiasis mansoni

المؤلفون: Rapado LN; Laboratório de Parasitologia, Instituto Butantan, São Paulo, Brazil., Pinheiro Ade S, Lopes PO, Fokoue HH, Scotti MT, Marques JV, Ohlweiler FP, Borrely SI, Pereira CA, Kato MJ, Nakano E, Yamaguchi LF

المصدر: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2013 Jun 06; Vol. 7 (6), pp. e2251. Date of Electronic Publication: 2013 Jun 06 (Print Publication: 2013).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE

مواضيع طبية MeSH: Antiparasitic Agents/*pharmacology , Biomphalaria/*drug effects , Biomphalaria/*parasitology , Piper/*chemistry , Piperidones/*pharmacology , Plant Extracts/*pharmacology, Animals ; Antiparasitic Agents/isolation & purification ; Biological Assay ; Magnetic Resonance Spectroscopy ; Piperidones/isolation & purification ; Plant Extracts/isolation & purification ; Spectrometry, Mass, Electrospray Ionization ; Survival Analysis

المؤلفون: Ndjonka D; Department of Biological Sciences, Faculty of Science, University of Ngaoundere, B. P. 454, Cameroon. liebaue@uni-muenster.de., Rapado LN, Silber AM, Liebau E, Wrenger C

المصدر: International journal of molecular sciences [Int J Mol Sci] 2013 Feb 06; Vol. 14 (2), pp. 3395-439. Date of Electronic Publication: 2013 Feb 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Print ISSN: 1422-0067 (Print) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: PubMed not MEDLINE

المؤلفون: Rapado LN; Instituto de Ciências Biomédicas, Universidade de São Paulo, Brazil. ludmilanr@usp.br, Nakano E, Ohlweiler FP, Kato MJ, Yamaguchi LF, Pereira CA, Kawano T

المصدر: Journal of helminthology [J Helminthol] 2011 Mar; Vol. 85 (1), pp. 66-72. Date of Electronic Publication: 2010 May 06.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: London School Of Hygiene And Tropical Medicine Country of Publication: England NLM ID: 2985115R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1475-2697 (Electronic) Linking ISSN: 0022149X NLM ISO Abbreviation: J Helminthol Subsets: MEDLINE

مواضيع طبية MeSH: Biomphalaria/*drug effects , Ovum/*drug effects , Piperaceae/*chemistry , Plant Extracts/*pharmacology, Animals ; Biomphalaria/growth & development ; Biomphalaria/parasitology ; Piperaceae/classification ; Plant Leaves/chemistry ; Plant Roots/chemistry ; Plant Stems/chemistry ; Schistosomiasis/prevention & control ; Species Specificity