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1
المؤلفون: R Galien, Raphael Geney, Koen Kurt Smits, Béatrice Vayssière, Thierry Christophe, Reginald Brys, L. Lepescheux, Ellen van der Aar, Luc Nelles, Fabrice Ciesielski, Guy Van Lommen, Pierre Deprez, Luc Juliaan Corina Van Rompaey, Muriel Uhring, Stephen Robert Fletcher, Christel Jeanne Marie Menet, Philippe Clément-Lacroix, Javier Blanc, Nolwenn Jouannigot
المصدر: Journal of Medicinal Chemistry. 57:9323-9342
مصطلحات موضوعية: Filgotinib, Pyridines, Chemistry, Pharmaceutical, Drug Evaluation, Preclinical, Crystallography, X-Ray, Inhibitory Concentration 50, Structure-Activity Relationship, Adenosine Triphosphate, Crohn Disease, Drug Discovery, JAK1 Inhibitor, Animals, Humans, Structure–activity relationship, Phosphorylation, Protein Kinase Inhibitors, Chemistry, Arthritis, Janus Kinase 1, Triazoles, Small molecule, Recombinant Proteins, Rats, Disease Models, Animal, Kinetics, Tyrosine kinase 2, Drug Design, Immunology, Cancer research, Cytokines, Molecular Medicine, Triazolopyridine, Collagen, Janus kinase, Dimerization
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2
مصطلحات موضوعية: Myeloproliferative Disorders, Kinase, Tyrosine kinase 2, JAK Family, Computational biology, Pharmacology, Biology, Signal transduction, Receptor, Transcription factor, Tyrosine kinase
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d7d4880621f209be38e1f60b75140d36
https://doi.org/10.1016/b978-0-444-62652-3.00004-1 -
3
المؤلفون: Christel Jeanne Marie Menet, Javier Blanc, Raphael Geney
المصدر: Anti-cancer agents in medicinal chemistry. 13(5)
مصطلحات موضوعية: Pharmacology, Cancer Research, Kinase, Rational design, Druggability, Cancer, Imatinib, Antineoplastic Agents, Biology, medicine.disease, Piperazines, Pyrimidines, Drug Design, Neoplasms, Benzamides, Cancer research, medicine, Imatinib Mesylate, Molecular Medicine, Animals, Humans, Protein Kinase Inhibitors, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::207bd7c526cda6978defcab19a35bcdf
https://pubmed.ncbi.nlm.nih.gov/23094911 -
4دورية أكاديمية
المؤلفون: Liang Sun, Xudong Geng, Raphael Geney, Yuan Li, Simmerling, Carlos, Zhong Li, Joseph W. Lauher, Shujun Xia, Horwitz, Susan B., Veith, Jean M., Pera, Paula, Bernacki, Ralph J., Ojima, Iwao
المصدر: Journal of Organic Chemistry; 12/19/2008, Vol. 73 Issue 24, p9584-9593, 10p, 1 Chart, 9 Graphs
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5كتاب إلكتروني
المؤلفون: Witty, D. R., Lawton, G.
نوع المادة: eBook.
الموضوعات: Pharmaceutical chemistry