المؤلفون: Vernochet, C, Mourier, A, Bezy, O, Macotela, Y, Boucher, J, Rardin, MJ, An, D, Lee, KY, Ilkayeva, OR, Zingaretti, CM, Emanuelli, B, Smyth, G, Cinti, S, Newgard, CB, Gibson, BW, Larsson, NG, Kahn, R

المصدر: Cell metabolism. 16(6):765-776

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:125804183

المؤلفون: Verdin, Eric, Zhang, Y, Bharathi, SS, Rardin, MJ, Uppala, R, Gibson, BW, Goetzman, ES

URL الوصول: https://escholarship.org/uc/item/15m3m6tm

المؤلفون: Verdin, Eric, Jing, E, O'Neill, BT, Rardin, MJ, Kleinridders, A, Ilkeyeva, OR, Ussar, S, Bain, JR, Lee, KY, Verdin, EM, Newgard, CB

URL الوصول: https://escholarship.org/uc/item/5376t1s5

المؤلفون: Zhang, Y, Bharathi, SS, Rardin, MJ, Uppala, R, Verdin, E, Gibson, BW, Goetzman, ES

مصطلحات الفهرس: Article, PeerReviewed

URL: http://d-scholarship.pitt.edu/28495/1/journal.pone.0122297.PDF
http://d-scholarship.pitt.edu/28495/3/licence.txt
http://worldcat.org/search?q=on:PIT+http://d-scholarship.pitt.edu/cgi/oai2+DCG_ENTIRE_REPOSITORY+CNTCOLL
http://d-scholarship.pitt.edu/28495/
http://d-scholarship.pitt.edu/28495
10.1371/journal.pone.0122297

المؤلفون: Guo Y; Research Biomarkers, Amgen Research, South San Francisco, California, USA., Gao Z; Cardiometabolic Disorders, Amgen Research, South San Francisco, California, USA., LaGory EL; Pharmacokinetics and Drug Metabolism, Amgen Research, South San Francisco, California, USA., Kristin LW; Translational Safety and Bioanalytical Sciences, Amgen Research, South San Francisco, California, USA., Gupte J; Cardiometabolic Disorders, Amgen Research, South San Francisco, California, USA., Gong Y; Cardiometabolic Disorders, Amgen Research, South San Francisco, California, USA., Rardin MJ; Discovery Technology Platforms, Amgen Research, South San Francisco, California, USA., Liu T; Center for Research Acceleration by Digital Innovation, Amgen Research, Cambridge, Massachusetts, USA., Nguyen TT; Center for Research Acceleration by Digital Innovation, Amgen Research, Cambridge, Massachusetts, USA., Long J; RNA Therapeutics, Amgen Research, One Amgen Center Drive, Thousand Oaks, California, USA., Hsu YH; Center for Research Acceleration by Digital Innovation, Amgen Research, Cambridge, Massachusetts, USA., Murray JK; RNA Therapeutics, Amgen Research, One Amgen Center Drive, Thousand Oaks, California, USA., Lade J; Pharmacokinetics and Drug Metabolism, Amgen Research, South San Francisco, California, USA., Jackson S; Cardiometabolic Disorders, Amgen Research, South San Francisco, California, USA., Zhang J; Cardiometabolic Disorders, Amgen Research, South San Francisco, California, USA.

المصدر: Hepatology communications [Hepatol Commun] 2024 May 02; Vol. 8 (5). Date of Electronic Publication: 2024 May 02 (Print Publication: 2024).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 101695860 Publication Model: eCollection Cited Medium: Internet ISSN: 2471-254X (Electronic) Linking ISSN: 2471254X NLM ISO Abbreviation: Hepatol Commun Subsets: MEDLINE

مواضيع طبية MeSH: Disease Models, Animal* , Hepatocytes*/metabolism , Gene Knockdown Techniques*, Animals ; Mice ; Liver/metabolism ; Male ; RNA, Small Interfering/genetics ; Mitochondrial Proteins/genetics ; Mitochondrial Proteins/metabolism ; Non-alcoholic Fatty Liver Disease/genetics ; Non-alcoholic Fatty Liver Disease/metabolism ; Non-alcoholic Fatty Liver Disease/prevention & control ; Mice, Inbred C57BL

المؤلفون: Dieters-Castator DZ; Discovery Proteomics, Amgen Research, South San Francisco, California 94080, United States., Manzanillo P; Inflammation, Amgen Research, South San Francisco, California 94080, United States., Yang HY; Discovery Proteomics, Amgen Research, South San Francisco, California 94080, United States., Modak RV; Inflammation, Amgen Research, South San Francisco, California 94080, United States., Rardin MJ; Discovery Proteomics, Amgen Research, South San Francisco, California 94080, United States., Gibson BW; Discovery Proteomics, Amgen Research, South San Francisco, California 94080, United States.

المصدر: Journal of proteome research [J Proteome Res] 2024 Feb 02; Vol. 23 (2), pp. 618-632. Date of Electronic Publication: 2024 Jan 16.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101128775 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-3907 (Electronic) Linking ISSN: 15353893 NLM ISO Abbreviation: J Proteome Res Subsets: MEDLINE

مواضيع طبية MeSH: Adenocarcinoma* , Colonic Neoplasms*, Humans ; Animals ; Mice ; Proteomics/methods ; Biotin ; Workflow ; Streptavidin ; Reproducibility of Results ; Membrane Glycoproteins ; Magnetic Phenomena ; Proteome

المؤلفون: Chow DT; Amgen Research, Discovery Attribute Sciences Amgen, South San Francisco, California 94080, United States., Rardin MJ; Amgen Research, Discovery Attribute Sciences Amgen, South San Francisco, California 94080, United States.

المصدر: Journal of the American Society for Mass Spectrometry [J Am Soc Mass Spectrom] 2022 Sep 07; Vol. 33 (9), pp. 1590-1597. Date of Electronic Publication: 2021 Oct 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: ACS Publications Country of Publication: United States NLM ID: 9010412 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1123 (Electronic) Linking ISSN: 10440305 NLM ISO Abbreviation: J Am Soc Mass Spectrom Subsets: MEDLINE

مواضيع طبية MeSH: Neoplasms* , Tandem Mass Spectrometry*, Chromatography, Liquid ; Defensins ; Humans ; Lung/chemistry ; Peptides/chemistry

المؤلفون: Boutoual R; Buck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, CA, 94945, USA. RBoutoual@buckinstitute.org., Jo H; Gladstone Institutes and University of California, San Francisco, San Francisco, CA, 94158, USA., Heckenbach I; Buck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, CA, 94945, USA.; Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark., Tiwari R; Buck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, CA, 94945, USA., Kasler H; Buck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, CA, 94945, USA., Lerner CA; Buck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, CA, 94945, USA., Shah S; Buck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, CA, 94945, USA., Schilling B, Calvanese V; Gladstone Institutes and University of California, San Francisco, San Francisco, CA, 94158, USA., Rardin MJ; Amgen Research, Amgen Inc., South San Francisco, CA, 94080, USA., Scheibye-Knudsen M; Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark., Verdin E; Buck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, CA, 94945, USA. EVerdin@buckinstitute.org.; Gladstone Institutes and University of California, San Francisco, San Francisco, CA, 94158, USA. EVerdin@buckinstitute.org.

المصدر: Scientific reports [Sci Rep] 2022 Aug 31; Vol. 12 (1), pp. 14804. Date of Electronic Publication: 2022 Aug 31.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Histone Acetyltransferases*/metabolism , RNA Processing, Post-Transcriptional*, Animals ; Mammals/metabolism ; Mitochondrial Proteins/genetics ; Mitochondrial Proteins/metabolism ; Protein Biosynthesis ; RNA, Mitochondrial/metabolism ; RNA, Transfer/genetics ; RNA, Transfer/metabolism

المؤلفون: Gut P; Gladstone Institutes and University of California, San Francisco, CA, 94158, USA. philipp.gut@rd.nestle.com.; Nestlé Research, Institute of Health Sciences, EPFL Innovation Park, 1015, Lausanne, Switzerland. philipp.gut@rd.nestle.com., Matilainen S; Research Program of Stem Cells and Metabolism, Biomedicum Helsinki, University of Helsinki, 00290, Helsinki, Finland., Meyer JG; Buck Institute for Research on Aging, Novato, CA, 94945, USA.; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI, 53213, USA., Pällijeff P; Research Program of Stem Cells and Metabolism, Biomedicum Helsinki, University of Helsinki, 00290, Helsinki, Finland., Richard J; Nestlé Research, Institute of Health Sciences, EPFL Innovation Park, 1015, Lausanne, Switzerland., Carroll CJ; Genetics Research Centre, Molecular and Clinical Sciences, St. George's, University of London, London, UK., Euro L; Research Program of Stem Cells and Metabolism, Biomedicum Helsinki, University of Helsinki, 00290, Helsinki, Finland., Jackson CB; Research Program of Stem Cells and Metabolism, Biomedicum Helsinki, University of Helsinki, 00290, Helsinki, Finland., Isohanni P; Research Program of Stem Cells and Metabolism, Biomedicum Helsinki, University of Helsinki, 00290, Helsinki, Finland.; Department of Child Neurology, Children's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Minassian BA; Program in Genetics and Genome Biology, The Hospital for Sick Children, Institute of Medical Science University of Toronto, Toronto, Ontario, Canada.; Division of Neurology, Department of Pediatrics, University of Texas Southwestern, Dallas, TX, USA., Alkhater RA; Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia., Østergaard E; Department of Clinical Genetics, Copenhagen University Hospital Rigshospitalet, 2100, Copenhagen, Denmark., Civiletto G; Nestlé Research, Institute of Health Sciences, EPFL Innovation Park, 1015, Lausanne, Switzerland., Parisi A; Nestlé Research, Institute of Health Sciences, EPFL Innovation Park, 1015, Lausanne, Switzerland., Thevenet J; Nestlé Research, Institute of Health Sciences, EPFL Innovation Park, 1015, Lausanne, Switzerland., Rardin MJ; Buck Institute for Research on Aging, Novato, CA, 94945, USA.; Amgen, Thousand Oaks, CA, 91320, USA., He W; Gladstone Institutes and University of California, San Francisco, CA, 94158, USA., Nishida Y; Gladstone Institutes and University of California, San Francisco, CA, 94158, USA., Newman JC; Gladstone Institutes and University of California, San Francisco, CA, 94158, USA., Liu X; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA.; North Carolina State University, Raleigh, NC, 27607, USA., Christen S; Nestlé Research, Institute of Health Sciences, EPFL Innovation Park, 1015, Lausanne, Switzerland., Moco S; Nestlé Research, Institute of Health Sciences, EPFL Innovation Park, 1015, Lausanne, Switzerland., Locasale JW; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA., Schilling B; Buck Institute for Research on Aging, Novato, CA, 94945, USA. bschilling@buckinstitute.org., Suomalainen A; Research Program of Stem Cells and Metabolism, Biomedicum Helsinki, University of Helsinki, 00290, Helsinki, Finland. anu.wartiovaara@helsinki.fi.; Neuroscience Center, HiLife, University of Helsinki, 00290, Helsinki, Finland. anu.wartiovaara@helsinki.fi.; HUSlab, Helsinki University Hospital, 00290, Helsinki, Finland. anu.wartiovaara@helsinki.fi., Verdin E; Gladstone Institutes and University of California, San Francisco, CA, 94158, USA. everdin@buckinstitute.org.; Buck Institute for Research on Aging, Novato, CA, 94945, USA. everdin@buckinstitute.org.

المصدر: Nature communications [Nat Commun] 2020 Nov 23; Vol. 11 (1), pp. 5927. Date of Electronic Publication: 2020 Nov 23.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Acyl Coenzyme A/*metabolism , Mitochondrial Diseases/*pathology , Succinate-CoA Ligases/*genetics, Animals ; Cells, Cultured ; Female ; Humans ; Infant ; Lysine/metabolism ; Male ; Mice ; Mice, Knockout ; Mitochondria/metabolism ; Mitochondrial Diseases/genetics ; Mitochondrial Diseases/metabolism ; Mutation ; Proteomics ; Sirtuins/deficiency ; Sirtuins/genetics ; Sirtuins/metabolism ; Succinate-CoA Ligases/deficiency ; Succinate-CoA Ligases/metabolism ; Survival Analysis ; Zebrafish

المؤلفون: Brauchle B; Gene Center, Laboratory for Translational Cancer Immunology, Ludwig-Maximilians-Universität München, Munich, Germany.; Department of Internal Medicine III, University Hospital, LMU Munich, Munich, Germany., Goldstein RL; Amgen Research, Amgen Inc., South San Francisco, California., Karbowski CM; Amgen Research, Amgen Inc., Thousand Oaks, California., Henn A; Amgen Research Munich GmbH, Munich, Germany., Li CM; Amgen Research, Amgen Inc., South San Francisco, California., Bücklein VL; Gene Center, Laboratory for Translational Cancer Immunology, Ludwig-Maximilians-Universität München, Munich, Germany.; Department of Internal Medicine III, University Hospital, LMU Munich, Munich, Germany., Krupka C; Gene Center, Laboratory for Translational Cancer Immunology, Ludwig-Maximilians-Universität München, Munich, Germany.; Department of Internal Medicine III, University Hospital, LMU Munich, Munich, Germany., Boyle MC; Amgen Research, Amgen Inc., Thousand Oaks, California., Koppikar P; Amgen Research, Amgen Inc., Thousand Oaks, California., Haubner S; Gene Center, Laboratory for Translational Cancer Immunology, Ludwig-Maximilians-Universität München, Munich, Germany.; Department of Internal Medicine III, University Hospital, LMU Munich, Munich, Germany., Wahl J; Amgen Research Munich GmbH, Munich, Germany., Dahlhoff C; Amgen Research Munich GmbH, Munich, Germany., Raum T; Amgen Research Munich GmbH, Munich, Germany., Rardin MJ; Amgen Research, Amgen Inc., South San Francisco, California., Sastri C; Amgen Research, Amgen Inc., South San Francisco, California., Rock DA; Amgen Research, Amgen Inc., South San Francisco, California., von Bergwelt-Baildon M; Gene Center, Laboratory for Translational Cancer Immunology, Ludwig-Maximilians-Universität München, Munich, Germany.; Department of Internal Medicine III, University Hospital, LMU Munich, Munich, Germany.; German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Heidelberg, Germany., Frank B; Amgen Research, Amgen Inc., South San Francisco, California., Metzeler KH; Department of Internal Medicine III, University Hospital, LMU Munich, Munich, Germany.; German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Heidelberg, Germany., Case R; Amgen Research, Amgen Inc., South San Francisco, California., Friedrich M; Amgen Research Munich GmbH, Munich, Germany., Balazs M; Amgen Research, Amgen Inc., South San Francisco, California., Spiekermann K; Department of Internal Medicine III, University Hospital, LMU Munich, Munich, Germany.; German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Heidelberg, Germany.; Experimental Leukemia and Lymphoma Research (ELLF), Department of Internal Medicine III, University Hospital, LMU Munich, Munich, Germany., Coxon A; Amgen Research Munich GmbH, Munich, Germany., Subklewe M; Gene Center, Laboratory for Translational Cancer Immunology, Ludwig-Maximilians-Universität München, Munich, Germany. taraa@amgen.com marion.subklewe@med.uni-muenchen.de.; Department of Internal Medicine III, University Hospital, LMU Munich, Munich, Germany.; German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Heidelberg, Germany., Arvedson T; Amgen Research, Amgen Inc., South San Francisco, California. taraa@amgen.com marion.subklewe@med.uni-muenchen.de.

المصدر: Molecular cancer therapeutics [Mol Cancer Ther] 2020 Sep; Vol. 19 (9), pp. 1875-1888. Date of Electronic Publication: 2020 Jun 09.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE

مواضيع طبية MeSH: Antibodies, Bispecific/*administration & dosage , Immune Checkpoint Inhibitors/*administration & dosage , Leukemia, Myeloid, Acute/*drug therapy , fms-Like Tyrosine Kinase 3/*metabolism, Animals ; Antibodies, Bispecific/pharmacology ; Cell Cycle ; Cell Line, Tumor ; Cell Proliferation ; Cell Survival ; Cytotoxicity, Immunologic ; Drug Synergism ; Humans ; Immune Checkpoint Inhibitors/pharmacology ; K562 Cells ; Leukemia, Myeloid, Acute/metabolism ; Macaca fascicularis ; Mice ; Treatment Outcome ; fms-Like Tyrosine Kinase 3/antagonists & inhibitors