المؤلفون: Zarou MM; Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK., Rattigan KM; Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK., Sarnello D; Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK., Shokry E; Cancer Research UK Scotland Institute, Glasgow, G61 1BD, UK., Dawson A; Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK., Ianniciello A; Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK., Dunn K; Paul O'Gorman Leukaemia Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, G12 0ZD, UK., Copland M; Paul O'Gorman Leukaemia Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, G12 0ZD, UK., Sumpton D; Cancer Research UK Scotland Institute, Glasgow, G61 1BD, UK., Vazquez A; Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK. avazque1@protonmail.com., Helgason GV; Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK. vignir.helgason@glasgow.ac.uk.

المصدر: Nature communications [Nat Commun] 2024 Mar 02; Vol. 15 (1), pp. 1931. Date of Electronic Publication: 2024 Mar 02.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Leukemia, Myeloid* , Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/drug therapy, Humans ; Mechanistic Target of Rapamycin Complex 1 ; AMP-Activated Protein Kinases ; Purines/therapeutic use ; Purine Nucleotides ; Folic Acid/metabolism

المؤلفون: Rattigan KM; Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, UK., Zarou MM; Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, UK., Brabcova Z; Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, UK., Prasad B; Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, UK., Zerbst D; Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, UK., Sarnello D; Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, UK., Kalkman ER; Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, UK., Ianniciello A; Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, UK., Scott MT; Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, UK., Dunn K; Paul O'Gorman Leukaemia Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, UK., Shokry E; Cancer Research UK Beatson Institute, Glasgow, UK., Sumpton D; Cancer Research UK Beatson Institute, Glasgow, UK., Copland M; Paul O'Gorman Leukaemia Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, UK., Tardito S; Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, UK.; Cancer Research UK Beatson Institute, Glasgow, UK., Vande Voorde J; Cancer Research UK Beatson Institute, Glasgow, UK., Mussai F; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK., Cheng P; Bio-cancer Treatment International Ltd, Hong Kong Science Park, Shatin, New Territories, Hong Kong., Helgason GV; Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, UK.

المصدر: EMBO reports [EMBO Rep] 2023 Oct 09; Vol. 24 (10), pp. e56279. Date of Electronic Publication: 2023 Jul 25.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE

مواضيع طبية MeSH: Arginine*/metabolism , Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/genetics , Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/drug therapy , Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/metabolism, Humans ; Apoptosis ; Stem Cells/metabolism ; Neoplastic Stem Cells/metabolism

المؤلفون: Rattigan KM; Wolfson Wohl Cancer Research Centre; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK., Brabcova Z; Wolfson Wohl Cancer Research Centre; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK., Sarnello D; Wolfson Wohl Cancer Research Centre; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK., Zarou MM; Wolfson Wohl Cancer Research Centre; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK., Roy K; Wolfson Wohl Cancer Research Centre; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK., Kwan R; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., de Beauchamp L; Wolfson Wohl Cancer Research Centre; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK., Dawson A; Wolfson Wohl Cancer Research Centre; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK., Ianniciello A; Wolfson Wohl Cancer Research Centre; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK., Khalaf A; Wolfson Wohl Cancer Research Centre; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK., Kalkman ER; Wolfson Wohl Cancer Research Centre; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK., Scott MT; Wolfson Wohl Cancer Research Centre; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK., Dunn K; Paul O'Gorman Leukaemia Research Centre; Institute of Cancer Sciences, University of Glasgow, Glasgow, G12 0ZD, UK., Sumpton D; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Michie AM; Paul O'Gorman Leukaemia Research Centre; Institute of Cancer Sciences, University of Glasgow, Glasgow, G12 0ZD, UK., Copland M; Paul O'Gorman Leukaemia Research Centre; Institute of Cancer Sciences, University of Glasgow, Glasgow, G12 0ZD, UK., Tardito S; Wolfson Wohl Cancer Research Centre; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK.; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Gottlieb E; The Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel., Vignir Helgason G; Wolfson Wohl Cancer Research Centre; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK. Vignir.Helgason@Glasgow.ac.uk.

المصدر: Nature communications [Nat Commun] 2023 Aug 17; Vol. 14 (1), pp. 4634. Date of Electronic Publication: 2023 Aug 17.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Pyruvic Acid* , Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/drug therapy , Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/genetics, Humans ; Imatinib Mesylate/pharmacology ; Imatinib Mesylate/therapeutic use ; Acclimatization ; Biological Assay

المؤلفون: Rattigan KM; Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., Zarou MM; Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., Helgason GV; Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom.

المصدر: Blood [Blood] 2023 May 25; Vol. 141 (21), pp. 2553-2565.

نوع المنشور: Review; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

مواضيع طبية MeSH: Hematopoiesis* , Leukemia*/metabolism, Humans ; Glycolysis ; Oxidation-Reduction ; Neoplastic Stem Cells/metabolism ; Stem Cell Niche

المؤلفون: Woodley K; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Dillingh LS; Wellcome - MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK., Giotopoulos G; Wellcome - MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Madrigal P; Wellcome - MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK.; European Molecular Biology Laboratory, European Bioinformatics Institute, EMBL-EBI, Hinxton, CB10 1SD, UK., Rattigan KM; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Philippe C; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Dembitz V; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Magee AMS; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Asby R; Department of Haematology, University of Cambridge, Cambridge, UK., van de Lagemaat LN; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Mapperley C; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., James SC; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Prehn JHM; Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland University of Medicine and Health Sciences, Dublin, Ireland., Tzelepis K; Wellcome - MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK.; Milner Therapeutics Institute, University of Cambridge, Cambridge, UK., Rouault-Pierre K; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Vassiliou GS; Wellcome - MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Kranc KR; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Helgason GV; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Huntly BJP; Wellcome - MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Gallipoli P; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK. p.gallipoli@qmul.ac.uk.

المصدر: Nature communications [Nat Commun] 2023 Apr 14; Vol. 14 (1), pp. 2132. Date of Electronic Publication: 2023 Apr 14.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Mannose* , Leukemia, Myeloid, Acute*/metabolism, Humans ; Cell Death ; Cytarabine/pharmacology ; Cell Line, Tumor ; Apoptosis ; fms-Like Tyrosine Kinase 3

المؤلفون: Ianniciello A; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK., Zarou MM; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK., Rattigan KM; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK., Scott M; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK., Dawson A; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK., Dunn K; Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow G12 0ZD, UK., Brabcova Z; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK., Kalkman ER; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK., Nixon C; Cancer Research UK Beatson Institute, Glasgow G61 1BD, UK., Michie AM; Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow G12 0ZD, UK., Copland M; Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow G12 0ZD, UK., Vetrie D; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK., Ambler M; LifeArc, Accelerator Building, Open Innovation Campus, Stevenage SG1 2FX, UK., Saxty B; LifeArc, Accelerator Building, Open Innovation Campus, Stevenage SG1 2FX, UK., Helgason GV; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK.

المصدر: Science translational medicine [Sci Transl Med] 2021 Sep 29; Vol. 13 (613), pp. eabd5016. Date of Electronic Publication: 2021 Sep 29.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

مواضيع طبية MeSH: Autophagy* , Oxidative Stress*, Autophagy-Related Protein-1 Homolog/metabolism ; Cell Differentiation ; Stem Cells/metabolism

المؤلفون: Rodgers LC; Centre of Immunobiology, University of Glasgow, Glasgow, UK.; GLAZgo Discovery Centre, Glasgow, UK., Cole J; GLAZgo Discovery Centre, Glasgow, UK., Rattigan KM; Wellcome Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, Glasgow, UK., Barrett MP; Wellcome Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, Glasgow, UK.; Glasgow Polyomics, Wolfson Wohl Cancer Research Centre, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Kurian N; Respiratory Inflammation and Autoimmune (RIA) Precision Medicine Unit, Precision Medicine, Oncology R&D, AstraZeneca, Gothenburg, Sweden., McInnes IB; Centre of Immunobiology, University of Glasgow, Glasgow, UK., Goodyear CS; Centre of Immunobiology, University of Glasgow, Glasgow, UK.; GLAZgo Discovery Centre, Glasgow, UK.

المصدر: Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2020 Apr 01; Vol. 59 (4), pp. 869-878.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 100883501 Publication Model: Print Cited Medium: Internet ISSN: 1462-0332 (Electronic) Linking ISSN: 14620324 NLM ISO Abbreviation: Rheumatology (Oxford) Subsets: MEDLINE

مواضيع طبية MeSH: Cellular Microenvironment* , Synovial Fluid*, Arthritis, Rheumatoid/*metabolism , Chemokine CCL20/*metabolism , Fatty Acids/*metabolism , Hypoxia/*metabolism , Monocytes/*metabolism, Carnitine/pharmacology ; Chemokine CCL20/drug effects ; Chromatography, Liquid ; Enzyme Inhibitors/pharmacology ; Epoxy Compounds/pharmacology ; Gene Expression Profiling ; Humans ; In Vitro Techniques ; Lipopolysaccharides/pharmacology ; Mass Spectrometry ; Metabolomics ; Microarray Analysis ; Monocytes/drug effects ; Synovial Membrane/metabolism

المؤلفون: Ianniciello A; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., Rattigan KM; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., Helgason GV; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom.

المصدر: Frontiers in cell and developmental biology [Front Cell Dev Biol] 2018 Sep 26; Vol. 6, pp. 120. Date of Electronic Publication: 2018 Sep 26 (Print Publication: 2018).

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101630250 Publication Model: eCollection Cited Medium: Print ISSN: 2296-634X (Print) Linking ISSN: 2296634X NLM ISO Abbreviation: Front Cell Dev Biol Subsets: PubMed not MEDLINE

المؤلفون: Rattigan KM; Wellcome Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom., Pountain AW; Wellcome Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom., Regnault C; Wellcome Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom., Achcar F; Wellcome Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom., Vincent IM; Wellcome Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom., Goodyear CS; Centre of Immunobiology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom., Barrett MP; Wellcome Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.; Glasgow Polyomics, Wolfson Wohl Cancer Research Centre, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.

المصدر: PloS one [PLoS One] 2018 Mar 14; Vol. 13 (3), pp. e0194126. Date of Electronic Publication: 2018 Mar 14 (Print Publication: 2018).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Metabolome*, Inflammation/*metabolism , Macrophages/*metabolism, Animals ; Cells, Cultured ; Immunoglobulins/metabolism ; Interferon-gamma/metabolism ; Lipopolysaccharides/metabolism ; Metabolomics/methods ; Mice, Inbred C57BL ; Ovalbumin/metabolism