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المؤلفون: Brian Nichelson, Mark G. Vartanian, Charles Taylor, Susan M. Lotarski, Nancy Sue Barta, Sean D. Donevan, Sian E. Gibbons, Norman L. Colbry, Zhu Zhijian, Melvin R. Dickerson, Paul Galatsis, Russell J. DeOrazio, Jacob Bradley Schwarz, Kristin Knapp Lin, Zheng Li, Andrew John Thorpe, Jack J. Kinsora, Raymond Andrew Hudack, David J. Wustrow, David D. Manning, Ayman El-Kattan
المصدر: Bioorganic & Medicinal Chemistry Letters. 16:3559-3563
مصطلحات موضوعية: Cyclohexanecarboxylic Acids, Stereochemistry, medicine.medical_treatment, Clinical Biochemistry, Carboxylic Acids, Drug Evaluation, Preclinical, Pregabalin, Pharmaceutical Science, Biochemistry, Chemical synthesis, Epilepsy, Reflex, Mice, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Drug Discovery, medicine, Animals, Tetrazole, Carboxylate, Amines, Molecular Biology, gamma-Aminobutyric Acid, Binding Sites, Molecular Structure, Organic Chemistry, Stereoisomerism, Biological activity, Disease Models, Animal, Protein Subunits, Anticonvulsant, chemistry, Mice, Inbred DBA, Molecular Medicine, Anticonvulsants, Bioisostere, Gabapentin, medicine.drug
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2
المؤلفون: Dong Liming, Xinjun Hou, Elizabeth A. Lunney, Corinne E. Augelli-Szafran, Deal Judith G, Christopher F. Bigge, Darin Vanderpool, Raymond Andrew Hudack, Nancy Sue Barta, Bradley William Caprathe, Chuangxing Guo, Steve Bender, Richard E. Showalter, Lorraine Kathleen Fay, Arindam Chatterjee
المصدر: Journal of Medicinal Chemistry. 49:1202-1206
مصطلحات موضوعية: Peptidylprolyl isomerase, Aza Compounds, Binding Sites, Neurite, Chemistry, Hydrogen Bonding, Biological activity, Tacrolimus Binding Protein 1A, Isoquinolines, Ligands, Amides, Heterocyclic Compounds, 4 or More Rings, Tacrolimus, Structure-Activity Relationship, Neuroprotective Agents, FKBP, Biochemistry, Cis-trans-Isomerases, Drug Discovery, Molecular Medicine, Structure–activity relationship, Binding site, Cognitive decline