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1دورية أكاديمية
المؤلفون: Haik Mkhikian, Christie-Lynn Mortales, Raymond W Zhou, Khachik Khachikyan, Gang Wu, Stuart M Haslam, Patil Kavarian, Anne Dell, Michael Demetriou
المصدر: eLife, Vol 5 (2016)
مصطلحات موضوعية: Golgi, N-glycosylation, bioequivalence, T cell, galectin, self-correction, Medicine, Science, Biology (General), QH301-705.5
وصف الملف: electronic resource
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المؤلفون: Haik Mkhikian, Ken L. Hayama, Khachik Khachikyan, Carey Li, Raymond W. Zhou, Judy Pawling, Suzi Klaus, Phuong Q. N. Tran, Kim M. Ly, Andrew D. Gong, Hayk Saryan, Jasper L. Hai, David Grigoryan, Philip L. Lee, Barbara L. Newton, Manuela Raffatellu, James W. Dennis, Michael Demetriou
المصدر: Nat Aging
Nature aging, vol 2, iss 3مصطلحات موضوعية: Aging, Immunosenescence, interleukin-7, Prevention, Neuroscience (miscellaneous), N-acetyglucosamine, T cell, N-glycosylation, immunity, infection, Article, Vaccine Related, Emerging Infectious Diseases, Infectious Diseases, Good Health and Well Being, Biodefense, 2.1 Biological and endogenous factors, Geriatrics and Gerontology, Aetiology, N-glycan branching
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10bd6d40714fef331e4b74d62d319202
https://europepmc.org/articles/PMC9075523/ -
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المؤلفون: David Chen, Araz Arakelyan, Haik Mkhikian, Michael A. Demetriou, Ani Grigorian, Raymond W. Zhou, Amanda Hong
المصدر: Nature Immunology. 15:1038-1045
مصطلحات موضوعية: Chemistry, Positive selection, Immunology, T-cell receptor, chemical and pharmacologic phenomena, Cell biology, Thymocyte, N-linked glycosylation, mental disorders, Immunology and Allergy, psychological phenomena and processes, Ca2 signaling, CD8, Decoupling (electronics)
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المؤلفون: Carey F. Li, Haik Mkhikian, Barbara L. Newton, Michael A. Demetriou, Zhaoxia Yu, Raymond W. Zhou
المصدر: Yu, Z; Li, CF; Mkhikian, H; Zhou, RW; Newton, BL; & Demetriou, M. (2014). Family studies of type 1 diabetes reveal additive and epistatic effects between MGAT1 and three other polymorphisms. Genes and Immunity, 15(4), 218-223. doi: 10.1038/gene.2014.7. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/39j0063f
Genes and immunity, vol 15, iss 4
Genes and immunityمصطلحات موضوعية: Male, type 1 diabetes, Datasets as Topic, N-glycosylation, 0302 clinical medicine, Receptors, genetic interaction, MGAT1, 2.1 Biological and endogenous factors, Cytotoxic T cell, CTLA-4 Antigen, Aetiology, Genetics (clinical), Pediatric, Genetics, 0303 health sciences, Diabetes, Female, Type 1, Immunology, Biology, N-Acetylglucosaminyltransferases, Autoimmune Disease, Article, 03 medical and health sciences, Genetic, Antigen, Genetic variation, Diabetes Mellitus, medicine, Humans, Family, Gene, Metabolic and endocrine, 030304 developmental biology, Type 1 diabetes, Receptors, Interleukin-7, Interleukin-7, Multiple sclerosis, Haplotype, Interleukin-2 Receptor alpha Subunit, Genetic Variation, Epistasis, Genetic, medicine.disease, Brain Disorders, Diabetes Mellitus, Type 1, Epistasis, 030217 neurology & neurosurgery
وصف الملف: application/pdf
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المؤلفون: Barbara L. Newton, Raymond W. Zhou, Carey F. Li, Haik Mkhikian, Michael A. Demetriou, Zhaoxia Yu
المصدر: Li, CF; Zhou, RW; Mkhikian, H; Newton, BL; Yu, Z; & Demetriou, M. (2013). Hypomorphic MGAT5 polymorphisms promote multiple sclerosis cooperatively with MGAT1 and interleukin-2 and 7 receptor variants. Journal of Neuroimmunology, 256(1-2), 71-76. doi: 10.1016/j.jneuroim.2012.12.008. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/1b5170sc
مصطلحات موضوعية: Adult, Male, Interleukin 2, Multiple Sclerosis, T-Lymphocytes, T cell, Immunology, Down-Regulation, Biology, N-Acetylglucosaminyltransferases, medicine.disease_cause, Article, Autoimmunity, Cohort Studies, Young Adult, symbols.namesake, Downregulation and upregulation, Risk Factors, medicine, Humans, Immunology and Allergy, CTLA-4 Antigen, Receptor, Interleukin-7 receptor, Receptors, Interleukin-7, Multiple sclerosis, Genetic Variation, Receptors, Interleukin-2, Middle Aged, Golgi apparatus, Flow Cytometry, Galactosyltransferases, medicine.disease, Molecular biology, medicine.anatomical_structure, Neurology, Case-Control Studies, Cancer research, symbols, Female, Neurology (clinical), medicine.drug
وصف الملف: application/pdf
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المؤلفون: Patil Kavarian, Stuart M. Haslam, Gang Wu, Christie-Lynn Mortales, Anne Dell, Haik Mkhikian, Michael A. Demetriou, Khachik Khachikyan, Raymond W. Zhou
المساهمون: Biotechnology and Biological Sciences Research Council (BBSRC), Wellcome Trust
المصدر: Mkhikian, Haik; Mortales, Christie-Lynn; Zhou, Raymond W; Khachikyan, Khachik; Wu, Gang; Haslam, Stuart M; et al.(2016). Golgi self-correction generates bioequivalent glycans to preserve cellular homeostasis. ELIFE, 5. doi: 10.7554/eLife.14814. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/0fb3v6d4
eLife
Mkhikian, H; Mortales, C-L; Zhou, RW; Khachikyan, K; Wu, G; Haslam, SM; et al.(2016). Golgi self-correction generates bioequivalent glycans to preserve cellular homeostasis.. eLife, 5. doi: 10.7554/eLife.14814. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/9dk0b4st
eLife, Vol 5 (2016)مصطلحات موضوعية: 0301 basic medicine, Life Sciences & Biomedicine - Other Topics, Mouse, T-Lymphocytes, Cell, Cellular homeostasis, Golgi Apparatus, N-glycosylation, 0601 Biochemistry and Cell Biology, Biochemistry, O-GLYCOSYLATION, HIGH-AFFINITY, Mice, N-linked glycosylation, Golgi, Homeostasis, Biology (General), Receptor, Cells, Cultured, galectin, biology, General Neuroscience, General Medicine, MULTIPLE-SCLEROSIS, ASPARAGINE-LINKED OLIGOSACCHARIDES, Cell biology, medicine.anatomical_structure, symbols, Medicine, Life Sciences & Biomedicine, Protein Binding, Research Article, Human, Glycan, QH301-705.5, T cell, Science, Galectins, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, symbols.namesake, ADVANCED MALIGNANCIES, Polysaccharides, medicine, Animals, Biology, Galectin, POLY-N-ACETYLLACTOSAMINE, Glycoproteins, bioequivalence, Science & Technology, COMPLEX, General Immunology and Microbiology, RECEPTOR, Cell Biology, Golgi apparatus, carbohydrates (lipids), 030104 developmental biology, self-correction, biology.protein, SURFACE ORGANIZATION
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c053eafa5045a298e3a389301303f2d
http://www.escholarship.org/uc/item/0fb3v6d4 -
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المؤلفون: Khachik Khachikyan, Patil Kavarian, Gang Wu, Christie-Lynn Mortales, Raymond W. Zhou, Anne Dell, Haik Mkhikian, Michael A. Demetriou, Stuart M. Haslam
مصطلحات موضوعية: symbols.namesake, Glycan, biology, Chemistry, symbols, biology.protein, Cellular homeostasis, Golgi apparatus, Bioequivalence, Self correction, Cell biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::35e6d9b0d4312a4cfbe18da7200bb3c3
https://doi.org/10.7554/elife.14814.021 -
8دورية أكاديمية
المؤلفون: Haik Mkhikian, Ani Grigorian, Carey F. Li, Hung-Lin Chen, Barbara Newton, Raymond W. Zhou, Christine Beeton, Sevan Torossian, Gevork Grikor Tatarian, Sung-Uk Lee, Ken Lau, Erin Walker, Kat
المصدر: Nature, Nature Communications. 2(1):1-13
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المؤلفون: Ken L Hayama, Khachik Khachikyan, Haik Mkhikian, Carey F Li, Raymond W Zhou, Suzi Klaus, Kim M Ly, Andrew D Gong, Manuela Raffatellu, Michael Demetriou
المصدر: The Journal of Immunology. 198:121.9-121.9
مصطلحات موضوعية: Immunology, Immunology and Allergy
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7d6c183d0659706ef0e86138dae09a4f
https://doi.org/10.4049/jimmunol.198.supp.121.9 -
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المؤلفون: Raymond W, Zhou, Haik, Mkhikian, Ani, Grigorian, Amanda, Hong, David, Chen, Araz, Arakelyan, Michael, Demetriou
المصدر: Nature immunology. 15(11)
مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Mice, Knockout, Glycosylation, Thymocytes, Receptors, Antigen, T-Cell, Cell Differentiation, CD8-Positive T-Lymphocytes, Lymphocyte Activation, N-Acetylglucosaminyltransferases, Major Histocompatibility Complex, Mice, Inbred C57BL, Mice, Lymphocyte Specific Protein Tyrosine Kinase p56(lck), Polysaccharides, Animals, Calcium, Calcium Signaling, Acyltransferases, Cells, Cultured