المؤلفون: Oriana Mandolfo, Helen Parker, Èlia Aguado, Yuko Ishikawa Learmonth, Ai Yin Liao, Claire O’Leary, Stuart Ellison, Gabriella Forte, Jessica Taylor, Shaun Wood, Rachel Searle, Rebecca J Holley, Hervé Boutin, Brian W Bigger

المصدر: EMBO Molecular Medicine, Vol 16, Iss 7, Pp 1579-1602 (2024)

مصطلحات موضوعية: Neurodegeneration, Neuroinflammation, Mucopolysaccharidosis, Sanfilippo, Inflammasome, Medicine (General), R5-920, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1757-4684

URL الوصول: https://doaj.org/article/6b33c2341e654421a1e1e4301ad75310

المؤلفون: Helen Parker, Stuart M Ellison, Rebecca J Holley, Claire O'Leary, Aiyin Liao, Jalal Asadi, Emily Glover, Arunabha Ghosh, Simon Jones, Fiona L Wilkinson, David Brough, Emmanuel Pinteaux, Hervé Boutin, Brian W Bigger

المصدر: EMBO Molecular Medicine, Vol 12, Iss 3, Pp n/a-n/a (2020)

مصطلحات موضوعية: cognitive decline, haematopoietic stem cell gene therapy, inflammasome, interleukin‐1 receptor antagonist, mucopolysaccharidosis, Medicine (General), R5-920, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

URL الوصول: https://doaj.org/article/860e4ff997044c5bbd042e03d9871bf4

المؤلفون: Hélène FE Gleitz, Ai Yin Liao, James R Cook, Samuel F Rowlston, Gabriella MA Forte, Zelpha D'Souza, Claire O'Leary, Rebecca J Holley, Brian W Bigger

المصدر: EMBO Molecular Medicine, Vol 10, Iss 7, Pp n/a-n/a (2018)

مصطلحات موضوعية: apolipoprotein E, blood–brain barrier, Hunter, mucopolysaccharidosis type II, stem cell gene therapy, Medicine (General), R5-920, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

URL الوصول: https://doaj.org/article/7b790fd6101949a990e17c2cd9b2efa6

المؤلفون: Hélène F E Gleitz, Claire O'Leary, Rebecca J Holley, Brian W Bigger

المصدر: PLoS ONE, Vol 12, Iss 2, p e0172435 (2017)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC5313159?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/625c86f024d540f58ec6dc67c394cfe7

المؤلفون: Fiona L Wilkinson, Rebecca J Holley, Kia J Langford-Smith, Soumya Badrinath, Aiyin Liao, Alex Langford-Smith, Jonathan D Cooper, Simon A Jones, J Ed Wraith, Rob F Wynn, Catherine L R Merry, Brian W Bigger

المصدر: PLoS ONE, Vol 7, Iss 4, p e35787 (2012)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3338781?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/795f2465ae6c40f69f556671f049448c

المؤلفون: Rebecca J. Holley, Guangping Tai, Andrew J.K. Williamson, Samuel Taylor, Stuart A. Cain, Stephen M. Richardson, Catherine L.R. Merry, Anthony D. Whetton, Cay M. Kielty, Ann E. Canfield

المصدر: Stem Cell Reports, Vol 4, Iss 3, Pp 473-488 (2015)

مصطلحات موضوعية: Medicine (General), R5-920, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213671115000284; https://doaj.org/toc/2213-6711

URL الوصول: https://doaj.org/article/6cc71db326e54606a55143823a1d825d

المؤلفون: Robert F Wynn, Jane L Kinsella, Rebecca J Holley, Jane Potter, Adrian J. Thrasher, Claire Booth, Karen Buckland, Natalia Izotova, Stewart Rust, Daniel Weisberg, Heather J Church, Karen L Tylee, Kathryn L Brammeier, Helena Lee, Laura Ford, Atusa Sadegholnejat, Simon A Jones, Stuart Ellison, Brian Bigger

المصدر: Blood. 140:1897-1898

مصطلحات موضوعية: Immunology, Cell Biology, Hematology, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a74997b32f145f5d1e80dc7d228c8086
https://doi.org/10.1182/blood-2022-168672

المؤلفون: Simon A. Jones, Jane L. Kinsella, Jane Potter, Adrian Thrasher, Claire Booth, Karen Buckland, Natalia Izotova, Stewart Rust, Daniel Weisberg, Heather Church, Karen Tylee, Helena Lee, Laura Ford, Rebecca J. Holley, Stuart Ellison, Brian W. Bigger, Robert F. Wynn

المصدر: Molecular Genetics and Metabolism. 135:S63-S64

مصطلحات موضوعية: Endocrinology, Endocrinology, Diabetes and Metabolism, Genetics, Molecular Biology, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7e6a835abc1e6c2675c302eb2a046e8d
https://doi.org/10.1016/j.ymgme.2021.11.159

المؤلفون: Aiyin Liao, Anu Goenka, Simon Jones, Brian W. Bigger, Arunabha Ghosh, Claire O'Leary, Karen Tylee, Rebecca J. Holley, Jean Mercer

المصدر: Molecular Therapy: Methods & Clinical Development, Vol 13, Iss, Pp 321-333 (2019)
Molecular Therapy. Methods & Clinical Development
Ghosh, A, Liao, A, O'Leary, C, Mercer, J, Tylee, K, Goenka, A, Holley, R, Jones, S A & Bigger, B W 2019, ' Strategies for the Induction of Immune Tolerance to Enzyme Replacement Therapy in Mucopolysaccharidosis Type I ', Molecular Therapy-Methods and Clinical Development, vol. 13, pp. 321-333 . https://doi.org/10.1016/j.omtm.2019.02.007

مصطلحات موضوعية: 0301 basic medicine, immune tolerance, Lydia Becker Institute, lcsh:QH426-470, medicine.drug_class, medicine.medical_treatment, haematopoietic stem cell transplantation, Hurler, Monoclonal antibody, Immunoglobulin G, Article, methotrexate, Immune tolerance, 03 medical and health sciences, Mucopolysaccharidosis type I, 0302 clinical medicine, ResearchInstitutes_Networks_Beacons/lydia_becker_institute_of_immunology_and_inflammation, Genetics, medicine, lcsh:QH573-671, Molecular Biology, biology, business.industry, lcsh:Cytology, mucopolysaccharidosis, Enzyme replacement therapy, lcsh:Genetics, 030104 developmental biology, lysosomal storage disease, 030220 oncology & carcinogenesis, Immunology, Monoclonal, biology.protein, Molecular Medicine, Antibody, antiCD8, business, Adjuvant, enzyme replacement therapy, antiCD4

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7fa2a8451b9998558df1d9a781de0b1
http://www.sciencedirect.com/science/article/pii/S2329050119300245

المؤلفون: Rebecca J. Holley, David Brough, Helen Parker, Hervé Boutin, Claire O'Leary, Simon Jones, Emmanuel Pinteaux, Emily Glover, Fiona L. Wilkinson, Stuart M. Ellison, Aiyin Liao, Arunabha Ghosh, Jalal Asadi, Brian W. Bigger

المصدر: EMBO Molecular Medicine, Vol 12, Iss 3, Pp n/a-n/a (2020)
Parker, H, Ellison, S M, Holley, R J, O'Leary, C, Liao, A, Asadi, J, Glover, E, Ghosh, A, Jones, S, Wilkinson, F L, Brough, D, Pinteaux, E, Boutin, H & Bigger, B W 2020, ' Haematopoietic stem cell gene therapy with IL-1Ra rescues cognitive loss in mucopolysaccharidosis IIIA ', EMBO Molecular Medicine, vol. 12, no. 3, e11185 . https://doi.org/10.15252/emmm.201911185
EMBO Molecular Medicine

مصطلحات موضوعية: 0301 basic medicine, Medicine (General), Inflammasomes, Mucopolysaccharidosis, Interleukin-1beta, interleukin‐1 receptor antagonist, QH426-470, Regenerative Medicine, Mice, Mucopolysaccharidosis III, Cognition, 0302 clinical medicine, Lysosomal storage disease, Cognitive decline, Child, Musculoskeletal System, Inflammasome, mucopolysaccharidosis, Articles, Haematopoiesis, Child, Preschool, Molecular Medicine, Female, Stem cell, medicine.drug, Adolescent, haematopoietic stem cell gene therapy, Article, 03 medical and health sciences, R5-920, inflammasome, medicine, Genetics, Animals, Humans, interleukin-1 receptor antagonist, Neuroinflammation, Amyloid beta-Peptides, business.industry, Genetic Therapy, Hematopoietic Stem Cells, medicine.disease, cognitive decline, Mice, Inbred C57BL, Interleukin 1 Receptor Antagonist Protein, 030104 developmental biology, Interleukin 1 receptor antagonist, Cancer research, Genetics, Gene Therapy & Genetic Disease, business, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::336b98f3eeaa07d928b77447092d2cd3
https://doaj.org/article/860e4ff997044c5bbd042e03d9871bf4