المؤلفون: Zhang Y; Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, The Second Hospital of Tianjin Medical University, Pingjiang Road 23rd, Tianjin, 300211, China., Yuan M; Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, The Second Hospital of Tianjin Medical University, Pingjiang Road 23rd, Tianjin, 300211, China., Cai W; Tianjin Key Laboratory of Metabolic Diseases, Key Laboratory of Immune Microenvironment and Disease-Ministry of Education, Department of Physiology and Pathophysiology, Collaborative Innovation Center of Tianjin for Medical Epigenetics, Tianjin Medical University, Qixiang Tai Road 22nd, Tianjin, 300070, China., Sun W; Tianjin Key Laboratory of Metabolic Diseases, Key Laboratory of Immune Microenvironment and Disease-Ministry of Education, Department of Physiology and Pathophysiology, Collaborative Innovation Center of Tianjin for Medical Epigenetics, Tianjin Medical University, Qixiang Tai Road 22nd, Tianjin, 300070, China., Shi X; Tianjin Key Laboratory of Metabolic Diseases, Key Laboratory of Immune Microenvironment and Disease-Ministry of Education, Department of Physiology and Pathophysiology, Collaborative Innovation Center of Tianjin for Medical Epigenetics, Tianjin Medical University, Qixiang Tai Road 22nd, Tianjin, 300070, China., Liu D; Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, The Second Hospital of Tianjin Medical University, Pingjiang Road 23rd, Tianjin, 300211, China., Song W; Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, The Second Hospital of Tianjin Medical University, Pingjiang Road 23rd, Tianjin, 300211, China., Yan Y; Department of Cardiac Surgery, The Second Hospital of Tianjin Medical University, Pingjiang Road 23rd, Tianjin, 300211, China., Chen T; Department of Cardiac Surgery, The Second Hospital of Tianjin Medical University, Pingjiang Road 23rd, Tianjin, 300211, China., Bao Q; Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, The Second Hospital of Tianjin Medical University, Pingjiang Road 23rd, Tianjin, 300211, China., Zhang B; Department of Cardiology, First Affiliated Hospital of Kunming Medical University, Xichang Road 295th, Kunming, 650032, China., Liu T; Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, The Second Hospital of Tianjin Medical University, Pingjiang Road 23rd, Tianjin, 300211, China., Zhu Y; Tianjin Key Laboratory of Metabolic Diseases, Key Laboratory of Immune Microenvironment and Disease-Ministry of Education, Department of Physiology and Pathophysiology, Collaborative Innovation Center of Tianjin for Medical Epigenetics, Tianjin Medical University, Qixiang Tai Road 22nd, Tianjin, 300070, China. zhuyi@tmu.edu.cn.; Department of Physiology and Pathophysiology, Tianjin Medical University, Qixiang Tai Road 22nd, Tianjin, 300070, China. zhuyi@tmu.edu.cn., Zhang X; Tianjin Key Laboratory of Metabolic Diseases, Key Laboratory of Immune Microenvironment and Disease-Ministry of Education, Department of Physiology and Pathophysiology, Collaborative Innovation Center of Tianjin for Medical Epigenetics, Tianjin Medical University, Qixiang Tai Road 22nd, Tianjin, 300070, China. xuzhang@tmu.edu.cn.; Department of Physiology and Pathophysiology, Tianjin Medical University, Qixiang Tai Road 22nd, Tianjin, 300070, China. xuzhang@tmu.edu.cn., Li G; Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, The Second Hospital of Tianjin Medical University, Pingjiang Road 23rd, Tianjin, 300211, China. tjcardiol@126.com.; Department of Cardiology, The Second Hospital of Tianjin Medical University, Pingjiang Road 23rd, Tianjin, 300211, China. tjcardiol@126.com.

المصدر: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2024 Jun 15; Vol. 81 (1), pp. 264. Date of Electronic Publication: 2024 Jun 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE

مواضيع طبية MeSH: Atrial Fibrillation*/metabolism , Atrial Fibrillation*/pathology , Atrial Fibrillation*/chemically induced , Atrial Fibrillation*/prevention & control , Angiotensin II* , Signal Transduction*/drug effects , Atrial Remodeling*/drug effects , Mice, Inbred C57BL* , Epoprostenol*/metabolism, Animals ; Mice ; Humans ; Male ; Fibrosis ; Fibroblasts/metabolism ; Fibroblasts/drug effects ; Fibroblasts/pathology ; Heart Atria/metabolism ; Heart Atria/pathology ; Heart Atria/drug effects ; Iloprost/pharmacology ; Receptors, Epoprostenol/metabolism ; Receptors, Epoprostenol/genetics ; Female

المؤلفون: Trif C; Cell Signalling Research Group, Institute of Biochemistry of the Romanian Academy, Bucharest, Romania., Banica AM; Cell Signalling Research Group, Institute of Biochemistry of the Romanian Academy, Bucharest, Romania., Manolache A; Department of Anatomy, Physiology, and Biophysics, Faculty of Biology, University of Bucharest, Bucharest, Romania., Anghel SA; Cell Signalling Research Group, Institute of Biochemistry of the Romanian Academy, Bucharest, Romania., Huţanu DE; Department of Anatomy, Physiology, and Biophysics, Faculty of Biology, University of Bucharest, Bucharest, Romania., Stratulat T; Cell Signalling Research Group, Institute of Biochemistry of the Romanian Academy, Bucharest, Romania.; Department of Anatomy, Physiology, and Biophysics, Faculty of Biology, University of Bucharest, Bucharest, Romania., Badea R; Cell Signalling Research Group, Institute of Biochemistry of the Romanian Academy, Bucharest, Romania., Oprita G; Department of Anatomy, Physiology, and Biophysics, Faculty of Biology, University of Bucharest, Bucharest, Romania., Selescu T; Department of Anatomy, Physiology, and Biophysics, Faculty of Biology, University of Bucharest, Bucharest, Romania., Petrescu SM; Cell Signalling Research Group, Institute of Biochemistry of the Romanian Academy, Bucharest, Romania., Sisignano M; Institute of Clinical Pharmacology, Pharmazentrum Frankfurt/ZAFES, University Hospital, Goethe-University, Frankfurt am Main, Germany., Offermanns S; Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany., Babes A; Department of Anatomy, Physiology, and Biophysics, Faculty of Biology, University of Bucharest, Bucharest, Romania., Tunaru S; Cell Signalling Research Group, Institute of Biochemistry of the Romanian Academy, Bucharest, Romania.; Prothanor Biotech S.R.L., Bucharest, Romania.

المصدر: British journal of pharmacology [Br J Pharmacol] 2024 May; Vol. 181 (9), pp. 1438-1451. Date of Electronic Publication: 2024 Jan 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Calcium*/metabolism , TRPM Cation Channels*/metabolism, Animals ; Mice ; Humans ; Receptors, Epoprostenol ; HEK293 Cells ; Menthol/pharmacology ; Pain ; Inflammation ; Membrane Proteins/metabolism

المؤلفون: Wang JJ; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.; Division of Cardiology, Department of Internal Medicine and Hubei Key Laboratory of Genetics and Molecular Mechanism of Cardiologic Disorders, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, China., Jin S; Lingang laboratory, Shanghai 200031, China.; School of Life Science and Technology, ShanghaiTech University, 201210 Shanghai, China., Zhang H; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China., Xu Y; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China., Hu W; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China., Jiang Y; Lingang laboratory, Shanghai 200031, China.; School of Life Science and Technology, ShanghaiTech University, 201210 Shanghai, China., Chen C; Division of Cardiology, Department of Internal Medicine and Hubei Key Laboratory of Genetics and Molecular Mechanism of Cardiologic Disorders, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, China., Wang DW; Division of Cardiology, Department of Internal Medicine and Hubei Key Laboratory of Genetics and Molecular Mechanism of Cardiologic Disorders, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, China., Xu HE; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.; School of Life Science and Technology, ShanghaiTech University, 201210 Shanghai, China.; University of Chinese Academy of Sciences, Beijing 100049, China., Wu C; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.

المصدر: Science advances [Sci Adv] 2024 Feb 09; Vol. 10 (6), pp. eadk5184. Date of Electronic Publication: 2024 Feb 09.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

مواضيع طبية MeSH: Acetates* , Antihypertensive Agents*/pharmacology , Antihypertensive Agents*/therapeutic use , GTP-Binding Proteins* , Pyrazines*, Humans ; Cryoelectron Microscopy ; Ligands ; Molecular Docking Simulation ; Receptors, Epoprostenol/agonists

المؤلفون: Stanger L; Department of Pharmacology, University of Michigan Medical School, Ann Arbor, MI., Yamaguchi A; Department of Pharmacology, University of Michigan Medical School, Ann Arbor, MI., Yalavarthi P; Department of Pharmacology, University of Michigan Medical School, Ann Arbor, MI., Lambert S; Department of Pharmacology, University of Michigan Medical School, Ann Arbor, MI., Gilmore D; Department of Pharmacology, University of Michigan Medical School, Ann Arbor, MI., Rickenberg A; Department of Pharmacology, University of Michigan Medical School, Ann Arbor, MI., Luke C; Department of Vascular Surgery, University of Michigan Medical School, Ann Arbor, MI., Kumar K; Department of Vascular Surgery, University of Michigan Medical School, Ann Arbor, MI., Obi AT; Department of Vascular Surgery, University of Michigan Medical School, Ann Arbor, MI., White A; Department of Medicinal Chemistry, University of Michigan Medical School, Ann Arbor, MI., Bergh N; Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.; Cereno Scientific, Gothenburg, Sweden.; Department of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden., Dahlöf B; Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.; Cereno Scientific, Gothenburg, Sweden., Holinstat M; Department of Pharmacology, University of Michigan Medical School, Ann Arbor, MI.; Department of Vascular Surgery, University of Michigan Medical School, Ann Arbor, MI.; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI.

المصدر: Blood [Blood] 2023 Nov 02; Vol. 142 (18), pp. 1556-1569.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

مواضيع طبية MeSH: Oxylipins*/pharmacology , Oxylipins*/therapeutic use , Thrombosis*, Animals ; Humans ; Mice ; Receptors, Epoprostenol ; Platelet Activation ; Blood Platelets ; Hemostasis ; Hemorrhage ; Platelet Aggregation

المؤلفون: Rondina MT; George E. Wahlen Department of Veterans Affairs Medical Center.

المصدر: Blood [Blood] 2023 Nov 02; Vol. 142 (18), pp. 1506-1507.

نوع المنشور: Editorial; Comment

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

مواضيع طبية MeSH: Epoprostenol* , Thrombosis*, Humans ; Receptors, Epoprostenol ; Oxylipins ; Prostaglandins I ; Pain ; Platelet Activation

المؤلفون: Chen M; China State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, China; Department of Clinical Medicine, The First Clinical School of Guangzhou Medical University, China., Lai Y; China State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, China; Department of Clinical Medicine, The First Clinical School of Guangzhou Medical University, China., Chen R; China State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, China., Lu J; China State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, China., Zhang Y; China State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, China., Liu H; China State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, China., Wang D; China State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, China., Zhong Y; China State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, China., Zheng Z; Department of Respiration, The Second Affiliated Hospital of Guangdong Medical University, China. Electronic address: 3342227603@qq.com., Hong C; China State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, China. Electronic address: gyfyyhc@126.com.

المصدر: Pulmonary pharmacology & therapeutics [Pulm Pharmacol Ther] 2022 Feb; Vol. 72, pp. 102100. Date of Electronic Publication: 2021 Nov 29.

نوع المنشور: Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Academic Press Country of Publication: England NLM ID: 9715279 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-9629 (Electronic) Linking ISSN: 10945539 NLM ISO Abbreviation: Pulm Pharmacol Ther Subsets: MEDLINE

مواضيع طبية MeSH: Antihypertensive Agents*/adverse effects , Hypertension, Pulmonary*/drug therapy , Receptors, Epoprostenol*/agonists, Acetamides/adverse effects ; Humans ; Pyrazines

المؤلفون: Tang SY; Institute for Translational Medicine and Therapeutics, Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Meng H; Institute for Translational Medicine and Therapeutics, Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Anderson ST; Institute for Translational Medicine and Therapeutics, Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Sarantopoulou D; Institute for Translational Medicine and Therapeutics, Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Ghosh S; Institute for Translational Medicine and Therapeutics, Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Lahens NF; Institute for Translational Medicine and Therapeutics, Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Theken KN; Institute for Translational Medicine and Therapeutics, Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Ricciotti E; Institute for Translational Medicine and Therapeutics, Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Hennessy EJ; Institute for Translational Medicine and Therapeutics, Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Tu V; Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Bittinger K; Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Weiljie AM; Institute for Translational Medicine and Therapeutics, Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Grant GR; Institute for Translational Medicine and Therapeutics, Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania, USA., FitzGerald GA; Institute for Translational Medicine and Therapeutics, Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

المصدر: The Journal of clinical investigation [J Clin Invest] 2021 Jul 15; Vol. 131 (14).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

مواضيع طبية MeSH: Blood Pressure* , Homeostasis* , Sex Characteristics*, Receptors, Epoprostenol/*deficiency, Animals ; Female ; Male ; Mice ; Mice, Knockout ; Prostaglandin-E Synthases/genetics ; Prostaglandin-E Synthases/metabolism ; Receptors, Epoprostenol/metabolism ; Receptors, LDL/genetics ; Receptors, LDL/metabolism

المؤلفون: Georges A; Paris Cardiovascular Research Center, Inserm, Université de Paris, 56 Rue Leblanc, F-75015 Paris, France., Albuisson J; Paris Cardiovascular Research Center, Inserm, Université de Paris, 56 Rue Leblanc, F-75015 Paris, France.; Department of Genetics, Assistance-publique-hôpitaux de Paris, Hopital Européen Georges Pompidou, F-75015 Paris, France., Berrandou T; Paris Cardiovascular Research Center, Inserm, Université de Paris, 56 Rue Leblanc, F-75015 Paris, France., Dupré D; Paris Cardiovascular Research Center, Inserm, Université de Paris, 56 Rue Leblanc, F-75015 Paris, France., Lorthioir A; Department of Hypertension, Assistance-publique-hôpitaux de Paris, Hopital Européen Georges Pompidou, F-75015 Paris, France., D'Escamard V; The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Di Narzo AF; The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Kadian-Dodov D; The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Olin JW; The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Warchol-Celinska E; Department of Hypertension, Institute of Cardiology, 04-628 Warsaw, Poland., Prejbisz A; Department of Hypertension, Institute of Cardiology, 04-628 Warsaw, Poland., Januszewicz A; Department of Hypertension, Institute of Cardiology, 04-628 Warsaw, Poland., Bruneval P; Paris Cardiovascular Research Center, Inserm, Université de Paris, 56 Rue Leblanc, F-75015 Paris, France., Baranowska AA; Department of Cardiovascular Sciences, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester LE5 4PW, UK., Webb TR; Department of Cardiovascular Sciences, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester LE5 4PW, UK., Hamby SE; Department of Cardiovascular Sciences, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester LE5 4PW, UK., Samani NJ; Department of Cardiovascular Sciences, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester LE5 4PW, UK., Adlam D; Department of Cardiovascular Sciences, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester LE5 4PW, UK., Fendrikova-Mahlay N; Department of Cardiovascular Medicine, Cleveland Clinic Heart and Vascular Institute, Cleveland, OH 44195, USA., Hazen S; Department of Cardiovascular Medicine, Cleveland Clinic Heart and Vascular Institute, Cleveland, OH 44195, USA., Wang Y; Division of Cardiovascular Medicine, Department of Internal Medicine, Michigan Medicine, University of Michigan, Ann Arbor, MI 48109-5856, USA.; Division of Cardiovascular Medicine, Department of Human Genetics, Michigan Medicine, University of Michigan, Ann Arbor, MI 48109-5618, USA., Yang ML; Division of Cardiovascular Medicine, Department of Internal Medicine, Michigan Medicine, University of Michigan, Ann Arbor, MI 48109-5856, USA.; Division of Cardiovascular Medicine, Department of Human Genetics, Michigan Medicine, University of Michigan, Ann Arbor, MI 48109-5618, USA., Hunker K; Division of Cardiovascular Medicine, Department of Internal Medicine, Michigan Medicine, University of Michigan, Ann Arbor, MI 48109-5856, USA.; Division of Cardiovascular Medicine, Department of Human Genetics, Michigan Medicine, University of Michigan, Ann Arbor, MI 48109-5618, USA., Combaret N; Department of Cardiology, University Hospital of Clermont-Ferrand, Auvergne University, F-63003 Clermont-Ferrand, France., Motreff P; Department of Cardiology, University Hospital of Clermont-Ferrand, Auvergne University, F-63003 Clermont-Ferrand, France., Chédid A; Department of Hypertension, Assistance-publique-hôpitaux de Paris, Hopital Européen Georges Pompidou, F-75015 Paris, France., Fiquet B; Department of Hypertension, Assistance-publique-hôpitaux de Paris, Hopital Européen Georges Pompidou, F-75015 Paris, France., Plouin PF; Department of Hypertension, Assistance-publique-hôpitaux de Paris, Hopital Européen Georges Pompidou, F-75015 Paris, France., Mousseaux E; Paris Cardiovascular Research Center, Inserm, Université de Paris, 56 Rue Leblanc, F-75015 Paris, France.; Department of Radiology, Assistance-publique-hôpitaux de Paris, Hopital Européen Georges Pompidou, F-75015 Paris, France., Azarine A; Department of Radiology, Assistance-publique-hôpitaux de Paris, Hopital Européen Georges Pompidou, F-75015 Paris, France., Amar L; Paris Cardiovascular Research Center, Inserm, Université de Paris, 56 Rue Leblanc, F-75015 Paris, France.; Department of Hypertension, Assistance-publique-hôpitaux de Paris, Hopital Européen Georges Pompidou, F-75015 Paris, France., Azizi M; Department of Hypertension, Assistance-publique-hôpitaux de Paris, Hopital Européen Georges Pompidou, F-75015 Paris, France.; Université de Paris, Inserm CIC1418, F-75015 Paris, France., Gornik HL; University Hospitals Harrington Heart and Vascular Institute, University Hospitals and Case Western Reserve University, Cleveland, OH 44106, USA., Ganesh SK; Division of Cardiovascular Medicine, Department of Internal Medicine, Michigan Medicine, University of Michigan, Ann Arbor, MI 48109-5856, USA.; Division of Cardiovascular Medicine, Department of Human Genetics, Michigan Medicine, University of Michigan, Ann Arbor, MI 48109-5618, USA., Kovacic JC; The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Victor Chang Cardiac Research Institute, Darlinghurst, NSW 2010, Australia.; St Vincent's Clinical School, University of NSW, Darlinghurst, NSW 2010, Australia., Jeunemaitre X; Paris Cardiovascular Research Center, Inserm, Université de Paris, 56 Rue Leblanc, F-75015 Paris, France.; Department of Genetics, Assistance-publique-hôpitaux de Paris, Hopital Européen Georges Pompidou, F-75015 Paris, France., Bouatia-Naji N; Paris Cardiovascular Research Center, Inserm, Université de Paris, 56 Rue Leblanc, F-75015 Paris, France.

المصدر: Cardiovascular research [Cardiovasc Res] 2021 Mar 21; Vol. 117 (4), pp. 1154-1165.

نوع المنشور: Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford Journals Country of Publication: England NLM ID: 0077427 Publication Model: Print Cited Medium: Internet ISSN: 1755-3245 (Electronic) Linking ISSN: 00086363 NLM ISO Abbreviation: Cardiovasc Res Subsets: MEDLINE

مواضيع طبية MeSH: Loss of Function Mutation* , Mutation, Missense*, Coronary Vessel Anomalies/*genetics , Fibromuscular Dysplasia/*genetics , Receptors, Epoprostenol/*genetics , Vascular Diseases/*congenital, Adult ; Aged ; Australia ; Coronary Vessel Anomalies/diagnosis ; Coronary Vessel Anomalies/metabolism ; DNA Mutational Analysis ; Databases, Genetic ; Europe ; Female ; Fibromuscular Dysplasia/diagnosis ; Fibromuscular Dysplasia/metabolism ; Genetic Predisposition to Disease ; HEK293 Cells ; Humans ; Male ; Middle Aged ; Phenotype ; Predictive Value of Tests ; Receptors, Epoprostenol/metabolism ; Risk Assessment ; Risk Factors ; United States ; Vascular Diseases/diagnosis ; Vascular Diseases/genetics ; Vascular Diseases/metabolism

SCR Disease Name: Coronary Artery Dissection, Spontaneous

المؤلفون: Vu SH; Institute of Applied Sciences, Ho Chi Minh City University of Technology - HUTECH, 475A Dien Bien Phu St., Ward 25, Binh Thanh District, Ho Chi Minh City, Viet Nam; Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju, 52828, Republic of Korea., Bernardo Reyes AW; Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju, 52828, Republic of Korea., Ngoc Huy TX; Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju, 52828, Republic of Korea., Min W; Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju, 52828, Republic of Korea., Lee HJ; Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju, 52828, Republic of Korea., Kim HJ; Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju, 52828, Republic of Korea., Lee JH; College of Veterinary Medicine, Chonbuk National University, Iksan, 54596, Republic of Korea., Kim S; Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju, 52828, Republic of Korea. Electronic address: kimsuk@gnu.ac.kr.

المصدر: Developmental and comparative immunology [Dev Comp Immunol] 2021 Feb; Vol. 115, pp. 103902. Date of Electronic Publication: 2020 Oct 19.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Country of Publication: United States NLM ID: 7708205 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0089 (Electronic) Linking ISSN: 0145305X NLM ISO Abbreviation: Dev Comp Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Brucella abortus/*immunology , Brucellosis/*drug therapy , Epoprostenol/*administration & dosage , Macrophages/*immunology , Receptors, Epoprostenol/*agonists, Acetamides/administration & dosage ; Animals ; Brucellosis/immunology ; Brucellosis/microbiology ; Cyclooxygenase 2/metabolism ; Cytochrome P-450 Enzyme System ; Female ; Humans ; Macrophages/metabolism ; Mice ; Pyrazines/administration & dosage ; RAW 264.7 Cells ; Receptors, Epoprostenol/metabolism ; Signal Transduction/drug effects ; Signal Transduction/immunology ; Specific Pathogen-Free Organisms

المؤلفون: Honda Y; Discovery Research Laboratories, Nippon Shinyaku Co., Ltd, Kyoto, Japan., Kosugi K; R&D Administration Division, Nippon Shinyaku Co., Ltd, Kyoto, Japan., Fuchikami C; Discovery Research Laboratories, Nippon Shinyaku Co., Ltd, Kyoto, Japan., Kuramoto K; R&D Administration Division, Nippon Shinyaku Co., Ltd, Kyoto, Japan., Numakura Y; Discovery Research Laboratories, Nippon Shinyaku Co., Ltd, Kyoto, Japan., Kuwano K; R&D Administration Division, Nippon Shinyaku Co., Ltd, Kyoto, Japan.

المصدر: PloS one [PLoS One] 2020 Oct 15; Vol. 15 (10), pp. e0240692. Date of Electronic Publication: 2020 Oct 15 (Print Publication: 2020).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Acetamides/*therapeutic use , Hypoxia/*complications , Pulmonary Arterial Hypertension/*drug therapy , Pulmonary Arterial Hypertension/*etiology , Pyrazines/*therapeutic use , Receptors, Epoprostenol/*agonists, 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid/pharmacology ; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid/therapeutic use ; Acetamides/pharmacology ; Animals ; Cell Proliferation/drug effects ; Collagen Type I/metabolism ; Disease Models, Animal ; Heart Ventricles/drug effects ; Heart Ventricles/physiopathology ; Hemodynamics/drug effects ; Hypertrophy, Right Ventricular/chemically induced ; Hypertrophy, Right Ventricular/physiopathology ; Hypoxia/physiopathology ; Indoles ; Lung/drug effects ; Lung/pathology ; Lung/physiopathology ; Male ; Pulmonary Arterial Hypertension/complications ; Pulmonary Arterial Hypertension/physiopathology ; Pyrazines/pharmacology ; Pyrroles ; Rats, Sprague-Dawley ; Receptors, Epoprostenol/metabolism ; Systole/drug effects ; Vascular Remodeling/drug effects