المؤلفون: Liu H; Department of Stomatology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China., Huang R; Department of Stomatology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China., Zhuo Z; Department of Stomatology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China., Zhang X; Department of Stomatology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China., Wu L; iView Therapeutics, Inc., Cranbury, NJ, USA., Guo Z; Department of Stomatology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China., Wen F; Department of Stomatology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China., An L; Department of Stomatology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China., Yuan H; Department of Stomatology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China. wishesyuanhang@tongji.edu.cn., Zhang Y; Department of Stomatology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China. zym811113@tongji.edu.cn., Xu Y; Department of Stomatology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China. xuyuanzhi@tongji.edu.cn.

المصدر: Cell communication and signaling : CCS [Cell Commun Signal] 2024 Jun 18; Vol. 22 (1), pp. 335. Date of Electronic Publication: 2024 Jun 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X (Electronic) Linking ISSN: 1478811X NLM ISO Abbreviation: Cell Commun Signal Subsets: MEDLINE

مواضيع طبية MeSH: Cell Membrane*/metabolism , Cell Membrane*/drug effects , Chondrocytes*/metabolism , Chondrocytes*/pathology , Chondrocytes*/drug effects , Osteoarthritis*/pathology , Osteoarthritis*/metabolism , Receptors, Opioid, kappa*/metabolism , Receptors, Opioid, kappa*/genetics , STAT3 Transcription Factor*/metabolism, Animals ; Male ; Mice ; 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer/pharmacology ; Mice, Inbred C57BL ; Signal Transduction/drug effects

المؤلفون: Li Z; National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR 72079, USA., Huang R; National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD 20892, USA., Xia M; National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD 20892, USA., Chang N; Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, MD 20993, USA., Guo W; National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR 72079, USA., Liu J; National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR 72079, USA., Dong F; National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR 72079, USA., Liu B; National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR 72079, USA., Varghese A; National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR 72079, USA., Aslam A; National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR 72079, USA., Patterson TA; National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR 72079, USA., Hong H; National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD 20892, USA.

المصدر: Molecules (Basel, Switzerland) [Molecules] 2024 Jun 03; Vol. 29 (11). Date of Electronic Publication: 2024 Jun 03.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, Opioid, kappa*/metabolism , Receptors, Opioid, kappa*/chemistry , Analgesics, Opioid*/chemistry , Analgesics, Opioid*/pharmacology, Humans ; Animals ; Binding Sites ; Ligands ; Signal Transduction/drug effects ; Protein Binding ; Structure-Activity Relationship ; Narcotic Antagonists/chemistry ; Pain/drug therapy ; Pain/metabolism

المؤلفون: Lalji HM; Department of Life Sciences, University of Bath, Bath, UK., Bailey CP; Department of Life Sciences, University of Bath, Bath, UK., Husbands SM; Department of Life Sciences, University of Bath, Bath, UK., Bailey SJ; Department of Life Sciences, University of Bath, Bath, UK.

المصدر: Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2024 Jun; Vol. 134 (6), pp. 792-804. Date of Electronic Publication: 2024 Apr 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Blackwell Country of Publication: England NLM ID: 101208422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-7843 (Electronic) Linking ISSN: 17427835 NLM ISO Abbreviation: Basic Clin Pharmacol Toxicol Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, Opioid, kappa*/agonists , Receptors, Opioid, kappa*/metabolism , Diuresis*/drug effects , Rats, Wistar* , 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer*/pharmacology, Animals ; Male ; Female ; Rats ; Sex Factors ; Diuretics/pharmacology ; Naltrexone/pharmacology ; Naltrexone/analogs & derivatives ; Sodium/urine ; Sodium/metabolism ; Organism Hydration Status/drug effects ; Potassium/urine ; Potassium/metabolism ; Dose-Response Relationship, Drug ; Narcotic Antagonists/pharmacology

المؤلفون: Li Z; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, No. 826 Zhangheng Road, Shanghai 201203, China., Ye R; CAS Key Laboratory of Receptor Research and State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, No. 555 Zuchongzhi Road, Shanghai 201203, China.; University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing 100049, China., He Q; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, No. 826 Zhangheng Road, Shanghai 201203, China., Lu J; CAS Key Laboratory of Receptor Research and State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, No. 555 Zuchongzhi Road, Shanghai 201203, China.; Department of Pharmacy, Dalian Medical University, Dalian 116044, China., Sun Y; Department of Neurobiology and Acupuncture Research, The Third Clinical Medical College, Zhejiang Chinese Medical University, Key Laboratory of Acupuncture and Neurobiology of Zhejiang Province, Hangzhou 310053, China., Sun X; Department of Neurobiology and Acupuncture Research, The Third Clinical Medical College, Zhejiang Chinese Medical University, Key Laboratory of Acupuncture and Neurobiology of Zhejiang Province, Hangzhou 310053, China., Tang S; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, No. 826 Zhangheng Road, Shanghai 201203, China., Hu S; CAS Key Laboratory of Receptor Research and State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, No. 555 Zuchongzhi Road, Shanghai 201203, China., Chai J; CAS Key Laboratory of Receptor Research and State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, No. 555 Zuchongzhi Road, Shanghai 201203, China., Kong L; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, No. 826 Zhangheng Road, Shanghai 201203, China., Liu X; Shandong Laboratory of Yantai Drug Discovery, Bohai Rim Advanced Research Institute for Drug Discovery, Yantai 264117, Shandong, China., Chen J; CAS Key Laboratory of Receptor Research and State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, No. 555 Zuchongzhi Road, Shanghai 201203, China., Fang Y; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, No. 826 Zhangheng Road, Shanghai 201203, China., Lan Y; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, No. 826 Zhangheng Road, Shanghai 201203, China., Xie Q; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, No. 826 Zhangheng Road, Shanghai 201203, China., Liu J; CAS Key Laboratory of Receptor Research and State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, No. 555 Zuchongzhi Road, Shanghai 201203, China.; University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing 100049, China.; Department of Neurobiology and Acupuncture Research, The Third Clinical Medical College, Zhejiang Chinese Medical University, Key Laboratory of Acupuncture and Neurobiology of Zhejiang Province, Hangzhou 310053, China., Shao L; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, No. 826 Zhangheng Road, Shanghai 201203, China., Fu W; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, No. 826 Zhangheng Road, Shanghai 201203, China., Wang Y; CAS Key Laboratory of Receptor Research and State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, No. 555 Zuchongzhi Road, Shanghai 201203, China.; University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing 100049, China.; Shandong Laboratory of Yantai Drug Discovery, Bohai Rim Advanced Research Institute for Drug Discovery, Yantai 264117, Shandong, China., Li W; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, No. 826 Zhangheng Road, Shanghai 201203, China.

المصدر: Journal of medicinal chemistry [J Med Chem] 2024 May 09; Vol. 67 (9), pp. 7112-7129. Date of Electronic Publication: 2024 Apr 22.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, Opioid, kappa*/agonists , Receptors, Opioid, kappa*/metabolism, Animals ; Mice ; Structure-Activity Relationship ; Male ; Humans ; Hypnotics and Sedatives/pharmacology ; Hypnotics and Sedatives/chemical synthesis ; Hypnotics and Sedatives/chemistry ; Rats ; Analgesics/pharmacology ; Analgesics/chemical synthesis ; Analgesics/chemistry ; Drug Discovery ; Rats, Sprague-Dawley ; Cricetulus

المؤلفون: Ji G; Department of Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, 3601 4th St., Lubbock, TX 79430, USA.; Center of Excellence for Translational Neuroscience and Therapeutics, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA., Presto P; Department of Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, 3601 4th St., Lubbock, TX 79430, USA.; Center of Excellence for Translational Neuroscience and Therapeutics, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA., Kiritoshi T; Department of Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, 3601 4th St., Lubbock, TX 79430, USA., Chen Y; Department of Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, 3601 4th St., Lubbock, TX 79430, USA.; Garrison Institute on Aging, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA., Navratilova E; Department of Pharmacology, Arizona Health Sciences Center, University of Arizona, Tucson, AZ 85721, USA., Porreca F; Department of Pharmacology, Arizona Health Sciences Center, University of Arizona, Tucson, AZ 85721, USA., Neugebauer V; Department of Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, 3601 4th St., Lubbock, TX 79430, USA.; Center of Excellence for Translational Neuroscience and Therapeutics, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.; Garrison Institute on Aging, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.

المصدر: Cells [Cells] 2024 Apr 19; Vol. 13 (8). Date of Electronic Publication: 2024 Apr 19.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, Opioid, kappa*/metabolism , Receptors, Opioid, kappa*/genetics , Neuralgia*/metabolism , Neuralgia*/physiopathology , Neurons*/metabolism , Amygdala*/metabolism , Mice, Transgenic*, Animals ; Mice ; Behavior, Animal ; Male ; Clozapine/analogs & derivatives ; Clozapine/pharmacology ; Central Amygdaloid Nucleus/metabolism

المؤلفون: Bao MY; Key Laboratory of Medicinal Resources and Natural Pharmaceutical Chemistry (Shaanxi Normal University), The Ministry of Education, College of Life Sciences, Shaanxi Normal University, Xi'an, Shaanxi 710119, China., Feng CY; Key Laboratory of Medicinal Resources and Natural Pharmaceutical Chemistry (Shaanxi Normal University), The Ministry of Education, College of Life Sciences, Shaanxi Normal University, Xi'an, Shaanxi 710119, China., Li XQ; Key Laboratory of Medicinal Resources and Natural Pharmaceutical Chemistry (Shaanxi Normal University), The Ministry of Education, College of Life Sciences, Shaanxi Normal University, Xi'an, Shaanxi 710119, China., He Y; Key Laboratory of Medicinal Resources and Natural Pharmaceutical Chemistry (Shaanxi Normal University), The Ministry of Education, College of Life Sciences, Shaanxi Normal University, Xi'an, Shaanxi 710119, China., Han B; Key Laboratory of Medicinal Resources and Natural Pharmaceutical Chemistry (Shaanxi Normal University), The Ministry of Education, College of Life Sciences, Shaanxi Normal University, Xi'an, Shaanxi 710119, China., Yang YN; Key Laboratory of Medicinal Resources and Natural Pharmaceutical Chemistry (Shaanxi Normal University), The Ministry of Education, College of Life Sciences, Shaanxi Normal University, Xi'an, Shaanxi 710119, China., Zhang Y; Key Laboratory of Medicinal Resources and Natural Pharmaceutical Chemistry (Shaanxi Normal University), The Ministry of Education, College of Life Sciences, Shaanxi Normal University, Xi'an, Shaanxi 710119, China. Electronic address: yuanzhang@snnu.edu.cn., Li X; Key Laboratory of Medicinal Resources and Natural Pharmaceutical Chemistry (Shaanxi Normal University), The Ministry of Education, College of Life Sciences, Shaanxi Normal University, Xi'an, Shaanxi 710119, China. Electronic address: lixing@snnu.edu.cn.

المصدر: International journal of biological macromolecules [Int J Biol Macromol] 2024 Jun; Vol. 269 (Pt 2), pp. 131964. Date of Electronic Publication: 2024 Apr 29.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

مواضيع طبية MeSH: Cell Differentiation*/drug effects , Famotidine*/pharmacology , Receptors, Opioid, kappa*/metabolism , Remyelination*/drug effects , Signal Transduction*/drug effects , STAT3 Transcription Factor*/metabolism, Animals ; Humans ; Mice ; Central Nervous System/drug effects ; Central Nervous System/metabolism ; Demyelinating Diseases/drug therapy ; Demyelinating Diseases/metabolism ; Myelin Sheath/metabolism ; Myelin Sheath/drug effects ; Oligodendrocyte Precursor Cells/drug effects ; Oligodendrocyte Precursor Cells/metabolism ; Oligodendrocyte Precursor Cells/cytology ; Oligodendroglia/drug effects ; Oligodendroglia/metabolism ; Oligodendroglia/cytology ; Female ; Mice, Inbred C57BL ; HEK293 Cells

المؤلفون: Kozell LB; VA Portland Health Care System (L.B.K., A.J.E., K.M.W., T.L.S., S.H.B., S.B., J.L.S., K.A.S., W.E.S., A.J., A.I.A.), Departments of Psychiatry (L.B.K., A.J.E., T.L.S., W.E.S., A.J., A.I.A.), and Behavioral Neuroscience (L.B.K., A.J., A.I.A.), Oregon Health and Science University, Portland, Oregon., Eshleman AJ; VA Portland Health Care System (L.B.K., A.J.E., K.M.W., T.L.S., S.H.B., S.B., J.L.S., K.A.S., W.E.S., A.J., A.I.A.), Departments of Psychiatry (L.B.K., A.J.E., T.L.S., W.E.S., A.J., A.I.A.), and Behavioral Neuroscience (L.B.K., A.J., A.I.A.), Oregon Health and Science University, Portland, Oregon., Wolfrum KM; VA Portland Health Care System (L.B.K., A.J.E., K.M.W., T.L.S., S.H.B., S.B., J.L.S., K.A.S., W.E.S., A.J., A.I.A.), Departments of Psychiatry (L.B.K., A.J.E., T.L.S., W.E.S., A.J., A.I.A.), and Behavioral Neuroscience (L.B.K., A.J., A.I.A.), Oregon Health and Science University, Portland, Oregon., Swanson TL; VA Portland Health Care System (L.B.K., A.J.E., K.M.W., T.L.S., S.H.B., S.B., J.L.S., K.A.S., W.E.S., A.J., A.I.A.), Departments of Psychiatry (L.B.K., A.J.E., T.L.S., W.E.S., A.J., A.I.A.), and Behavioral Neuroscience (L.B.K., A.J., A.I.A.), Oregon Health and Science University, Portland, Oregon., Bloom SH; VA Portland Health Care System (L.B.K., A.J.E., K.M.W., T.L.S., S.H.B., S.B., J.L.S., K.A.S., W.E.S., A.J., A.I.A.), Departments of Psychiatry (L.B.K., A.J.E., T.L.S., W.E.S., A.J., A.I.A.), and Behavioral Neuroscience (L.B.K., A.J., A.I.A.), Oregon Health and Science University, Portland, Oregon., Benware S; VA Portland Health Care System (L.B.K., A.J.E., K.M.W., T.L.S., S.H.B., S.B., J.L.S., K.A.S., W.E.S., A.J., A.I.A.), Departments of Psychiatry (L.B.K., A.J.E., T.L.S., W.E.S., A.J., A.I.A.), and Behavioral Neuroscience (L.B.K., A.J., A.I.A.), Oregon Health and Science University, Portland, Oregon., Schmachtenberg JL; VA Portland Health Care System (L.B.K., A.J.E., K.M.W., T.L.S., S.H.B., S.B., J.L.S., K.A.S., W.E.S., A.J., A.I.A.), Departments of Psychiatry (L.B.K., A.J.E., T.L.S., W.E.S., A.J., A.I.A.), and Behavioral Neuroscience (L.B.K., A.J., A.I.A.), Oregon Health and Science University, Portland, Oregon., Schutzer KA; VA Portland Health Care System (L.B.K., A.J.E., K.M.W., T.L.S., S.H.B., S.B., J.L.S., K.A.S., W.E.S., A.J., A.I.A.), Departments of Psychiatry (L.B.K., A.J.E., T.L.S., W.E.S., A.J., A.I.A.), and Behavioral Neuroscience (L.B.K., A.J., A.I.A.), Oregon Health and Science University, Portland, Oregon., Schutzer WE; VA Portland Health Care System (L.B.K., A.J.E., K.M.W., T.L.S., S.H.B., S.B., J.L.S., K.A.S., W.E.S., A.J., A.I.A.), Departments of Psychiatry (L.B.K., A.J.E., T.L.S., W.E.S., A.J., A.I.A.), and Behavioral Neuroscience (L.B.K., A.J., A.I.A.), Oregon Health and Science University, Portland, Oregon., Janowsky A; VA Portland Health Care System (L.B.K., A.J.E., K.M.W., T.L.S., S.H.B., S.B., J.L.S., K.A.S., W.E.S., A.J., A.I.A.), Departments of Psychiatry (L.B.K., A.J.E., T.L.S., W.E.S., A.J., A.I.A.), and Behavioral Neuroscience (L.B.K., A.J., A.I.A.), Oregon Health and Science University, Portland, Oregon., Abbas AI; VA Portland Health Care System (L.B.K., A.J.E., K.M.W., T.L.S., S.H.B., S.B., J.L.S., K.A.S., W.E.S., A.J., A.I.A.), Departments of Psychiatry (L.B.K., A.J.E., T.L.S., W.E.S., A.J., A.I.A.), and Behavioral Neuroscience (L.B.K., A.J., A.I.A.), Oregon Health and Science University, Portland, Oregon abbasat@ohsu.edu.

المصدر: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2024 Apr 18; Vol. 389 (2), pp. 219-228. Date of Electronic Publication: 2024 Apr 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0376362 Publication Model: Electronic Cited Medium: Internet ISSN: 1521-0103 (Electronic) Linking ISSN: 00223565 NLM ISO Abbreviation: J Pharmacol Exp Ther Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, Opioid, delta*/metabolism , Receptors, Opioid, kappa*/metabolism, Cricetinae ; Animals ; Humans ; Cricetulus ; Receptors, Opioid, mu/metabolism ; Analgesics, Opioid/pharmacology ; Fentanyl/pharmacology ; Benzimidazoles

المؤلفون: Cayir S; Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT 06510, USA., Zhornitsky S; Department of Psychology, Southern Connecticut State University, New Haven, CT 06515, USA., Barzegary A; Islamic Azad University Tehran Medical Sciences School of Medicine, Iran., Sotomayor-Carreño E; Pontifical Kavierian University, Bogotá, Colombia., Sarfo-Ansah W; University of Ghana Medical School, Accra, Ghana., Funaro MC; Harvey Cushing/John Hay Whitney Medical Library, Yale University, New Haven, CT 06510, USA., Matuskey D; Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT 06510, USA; Department of Psychiatry, Yale University School of Medicine, 300 George Street, Suite 901, New Haven, CT 06511, USA; Department of Neurology, Yale University, New Haven, CT 06510, USA., Angarita G; Department of Psychiatry, Yale University School of Medicine, 300 George Street, Suite 901, New Haven, CT 06511, USA; Clinical Neuroscience Research Unit, Connecticut Mental Health Center, 34 Park Street, New Haven, CT 06519, USA. Electronic address: gustavo.angarita@yale.edu.

المصدر: Neuroscience and biobehavioral reviews [Neurosci Biobehav Rev] 2024 Jul; Vol. 162, pp. 105713. Date of Electronic Publication: 2024 May 10.

نوع المنشور: Journal Article; Systematic Review; Review

بيانات الدورية: Publisher: Pergamon Press Country of Publication: United States NLM ID: 7806090 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7528 (Electronic) Linking ISSN: 01497634 NLM ISO Abbreviation: Neurosci Biobehav Rev Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, Opioid, kappa*/metabolism , Receptors, Opioid, kappa*/agonists, Humans ; Animals ; Opioid-Related Disorders/metabolism ; Analgesics, Opioid/pharmacology ; Dynorphins/metabolism ; Substance Withdrawal Syndrome/metabolism

المؤلفون: Bowe A; West Virginia University School of Medicine-Charleston, Charleston, WV, USA. adbowe@hsc.wvu.edu., Kerr PL; West Virginia University School of Medicine-Charleston, Charleston, WV, USA.

المصدر: Advances in neurobiology [Adv Neurobiol] 2024; Vol. 35, pp. 287-313.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Springer Country of Publication: United States NLM ID: 101571545 Publication Model: Print Cited Medium: Print ISSN: 2190-5215 (Print) NLM ISO Abbreviation: Adv Neurobiol Subsets: MEDLINE

مواضيع طبية MeSH: Mitragyna* , Plant Extracts*/pharmacology , Receptors, Opioid, kappa*/metabolism , Receptors, Opioid, kappa*/agonists, Humans ; Animals ; Analgesics, Opioid/pharmacology ; Analgesics, Opioid/therapeutic use ; Receptors, Opioid, mu/metabolism ; Receptors, Opioid, mu/agonists ; Asia, Southeastern

المؤلفون: Kansagra KA; Zydus Research Centre, Clinical R & D, Zydus Lifesciences Limited, Sarkhej-Bavla N. H. No. 8 A, Moraiya, Ahmedabad, 382213, Gujarat, India. kevinkumarkansagra@zyduslife.com., Momin T; Zydus Therapeutics Inc., Pennington, NJ, USA., Patel HB; Zydus Research Centre, Clinical R & D, Zydus Lifesciences Limited, Sarkhej-Bavla N. H. No. 8 A, Moraiya, Ahmedabad, 382213, Gujarat, India., Shah C; Zydus Research Centre, Clinical R & D, Zydus Lifesciences Limited, Sarkhej-Bavla N. H. No. 8 A, Moraiya, Ahmedabad, 382213, Gujarat, India., Parmar G; Zydus Research Centre, Clinical R & D, Zydus Lifesciences Limited, Sarkhej-Bavla N. H. No. 8 A, Moraiya, Ahmedabad, 382213, Gujarat, India., Ghoghari A; Zydus Research Centre, Clinical R & D, Zydus Lifesciences Limited, Sarkhej-Bavla N. H. No. 8 A, Moraiya, Ahmedabad, 382213, Gujarat, India., Patel HV; Zydus Research Centre, Clinical R & D, Zydus Lifesciences Limited, Sarkhej-Bavla N. H. No. 8 A, Moraiya, Ahmedabad, 382213, Gujarat, India., Parmar DV; Zydus Therapeutics Inc., Pennington, NJ, USA.

المصدر: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2024 Jul; Vol. 397 (7), pp. 4737-4745. Date of Electronic Publication: 2023 Dec 23.

نوع المنشور: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase I

بيانات الدورية: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, Opioid, kappa*/agonists, Humans ; Male ; Double-Blind Method ; Adult ; Young Adult ; Middle Aged ; Adolescent ; Healthy Volunteers ; Dose-Response Relationship, Drug ; Oligopeptides ; Azabicyclo Compounds