المؤلفون: Grauwet K; Cellular Immunotherapy Program, Krantz Family Center for Cancer Research, Massachusetts General Hosptial, Charlestown, Massachusetts, USA.; Harvard Medical School, Boston, Massachusetts, USA., Berger T; Cellular Immunotherapy Program, Krantz Family Center for Cancer Research, Massachusetts General Hosptial, Charlestown, Massachusetts, USA., Kann MC; Cellular Immunotherapy Program, Krantz Family Center for Cancer Research, Massachusetts General Hosptial, Charlestown, Massachusetts, USA., Silva H; Cellular Immunotherapy Program, Krantz Family Center for Cancer Research, Massachusetts General Hosptial, Charlestown, Massachusetts, USA., Larson R; Cellular Immunotherapy Program, Krantz Family Center for Cancer Research, Massachusetts General Hosptial, Charlestown, Massachusetts, USA.; Harvard Medical School, Boston, Massachusetts, USA., Leick MB; Cellular Immunotherapy Program, Krantz Family Center for Cancer Research, Massachusetts General Hosptial, Charlestown, Massachusetts, USA.; Harvard Medical School, Boston, Massachusetts, USA.; Cancer Center, Massachusetts General Hospital, Boston, Massachusetts, USA.; Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA., Bailey SR; Cellular Immunotherapy Program, Krantz Family Center for Cancer Research, Massachusetts General Hosptial, Charlestown, Massachusetts, USA.; Harvard Medical School, Boston, Massachusetts, USA., Bouffard AA; Cellular Immunotherapy Program, Krantz Family Center for Cancer Research, Massachusetts General Hosptial, Charlestown, Massachusetts, USA., Millar D; Cancer Center, Massachusetts General Hospital, Boston, Massachusetts, USA., Gallagher K; Cellular Immunotherapy Program, Krantz Family Center for Cancer Research, Massachusetts General Hosptial, Charlestown, Massachusetts, USA.; Harvard Medical School, Boston, Massachusetts, USA.; Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts, USA., Turtle CJ; Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.; Department of Medicine, University of Washington, Seattle, Washington, USA., Frigault MJ; Cellular Immunotherapy Program, Krantz Family Center for Cancer Research, Massachusetts General Hosptial, Charlestown, Massachusetts, USA.; Harvard Medical School, Boston, Massachusetts, USA.; Cancer Center, Massachusetts General Hospital, Boston, Massachusetts, USA.; Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA., Maus MV; Cellular Immunotherapy Program, Krantz Family Center for Cancer Research, Massachusetts General Hosptial, Charlestown, Massachusetts, USA mvmaus@mgh.harvard.edu.; Harvard Medical School, Boston, Massachusetts, USA.; Cancer Center, Massachusetts General Hospital, Boston, Massachusetts, USA.; Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.

المصدر: Journal for immunotherapy of cancer [J Immunother Cancer] 2024 May 09; Vol. 12 (5). Date of Electronic Publication: 2024 May 09.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101620585 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-1426 (Electronic) Linking ISSN: 20511426 NLM ISO Abbreviation: J Immunother Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, Chimeric Antigen*/immunology , Receptors, Chimeric Antigen*/genetics , Immunotherapy, Adoptive*/methods, Animals ; Humans ; Mice ; Transgenes ; T-Lymphocytes/immunology

المؤلفون: Chiawpanit C; Cell Engineering for Cancer Therapy Research Group, Chiang Mai University, Chiang Mai, Thailand; Department of Biology, Faculty of Science, Chiang Mai University, Chiang Mai, Thailand; Office of Research Administration, Chiang Mai University, Chiang Mai, Thailand., Wathikthinnakorn M; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Sawasdee N; Siriraj Center of Research Excellence for Cancer Immunotherapy (SiCORE-CIT), Research Department, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand., Phanthaphol N; College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom., Sujjitjoon J; Siriraj Center of Research Excellence for Cancer Immunotherapy (SiCORE-CIT), Research Department, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand., Junking M; Siriraj Center of Research Excellence for Cancer Immunotherapy (SiCORE-CIT), Research Department, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand., Yamabhai M; Molecular Biotechnology Laboratory, School of Biotechnology, Institute of Agriculture Technology, Suranaree University of Technology, Nakhon Ratchasima, Thailand., Panaampon J; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Yenchitsomanus PT; Siriraj Center of Research Excellence for Cancer Immunotherapy (SiCORE-CIT), Research Department, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand., Panya A; Cell Engineering for Cancer Therapy Research Group, Chiang Mai University, Chiang Mai, Thailand; Department of Biology, Faculty of Science, Chiang Mai University, Chiang Mai, Thailand. Electronic address: aussara.pan@cmu.ac.th.

المصدر: International immunopharmacology [Int Immunopharmacol] 2024 Jul 30; Vol. 136, pp. 112273. Date of Electronic Publication: 2024 May 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Single-Chain Antibodies*/genetics , Single-Chain Antibodies*/therapeutic use , Single-Chain Antibodies*/immunology , Cholangiocarcinoma*/therapy , Cholangiocarcinoma*/immunology , Receptors, Chimeric Antigen*/immunology , Receptors, Chimeric Antigen*/genetics , Receptors, Chimeric Antigen*/metabolism , Killer Cells, Natural*/immunology , Bile Duct Neoplasms*/therapy , Bile Duct Neoplasms*/immunology , Proto-Oncogene Proteins c-met*/metabolism , Proto-Oncogene Proteins c-met*/immunology, Humans ; Cell Line, Tumor ; Immunotherapy, Adoptive/methods ; Immunotherapy/methods ; Precision Medicine

المؤلفون: Hu J; Department of Laboratory Medicine, Gongli Hospital, No. 219, Miaopu Road, Pudong, Shanghai, 200135, China. Electronic address: hjh7677@sina.com., Liu X; TriArm Therapeutics Inc, Building 5, Niudun Road, Pudong New District, Shanghai, 201203, China. Electronic address: xiang.liu@triarmbio.com.

المصدر: International immunopharmacology [Int Immunopharmacol] 2024 Jul 30; Vol. 136, pp. 112379. Date of Electronic Publication: 2024 Jun 03.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Immunotherapy, Adoptive*/methods , Receptors, Chimeric Antigen*/immunology , Receptors, Chimeric Antigen*/metabolism , Receptors, Chimeric Antigen*/genetics , T-Lymphocytes*/immunology, Humans ; Animals ; Cell Differentiation ; Neoplasms/therapy ; Neoplasms/immunology

المؤلفون: Hughes AD; Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Teachey DT; Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.; Immune Dysregulation Frontier Program, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Diorio C; Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA. diorioc@chop.edu.; Immune Dysregulation Frontier Program, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA. diorioc@chop.edu.

المصدر: Seminars in immunopathology [Semin Immunopathol] 2024 Jul 16; Vol. 46 (3-4), pp. 5. Date of Electronic Publication: 2024 Jul 16.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Springer Country of Publication: Germany NLM ID: 101308769 Publication Model: Electronic Cited Medium: Internet ISSN: 1863-2300 (Electronic) Linking ISSN: 18632297 NLM ISO Abbreviation: Semin Immunopathol Subsets: MEDLINE

مواضيع طبية MeSH: Immunotherapy, Adoptive*/adverse effects , Immunotherapy, Adoptive*/methods , Cytokine Release Syndrome*/etiology , Cytokine Release Syndrome*/therapy , Receptors, Chimeric Antigen*/metabolism , Receptors, Chimeric Antigen*/immunology , Receptors, Chimeric Antigen*/genetics , Neoplasms*/therapy , Neoplasms*/immunology , Neoplasms*/etiology , Cytokines*/metabolism, Humans ; Animals ; Neurotoxicity Syndromes/etiology ; Neurotoxicity Syndromes/therapy ; Disease Management ; Lymphohistiocytosis, Hemophagocytic/therapy ; Lymphohistiocytosis, Hemophagocytic/etiology ; Lymphohistiocytosis, Hemophagocytic/immunology ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism

المؤلفون: Tarannum M; Division of Transplantation and Cellular Therapies, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Dinh K; Division of Transplantation and Cellular Therapies, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Vergara J; Division of Transplantation and Cellular Therapies, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Birch G; Division of Transplantation and Cellular Therapies, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Abdulhamid YZ; Division of Transplantation and Cellular Therapies, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Kaplan IE; Division of Transplantation and Cellular Therapies, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Ay O; Division of Transplantation and Cellular Therapies, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Maia A; Division of Transplantation and Cellular Therapies, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Beaver O; Division of Transplantation and Cellular Therapies, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Sheffer M; Division of Transplantation and Cellular Therapies, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Shapiro R; Division of Transplantation and Cellular Therapies, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Ali AK; Division of Transplantation and Cellular Therapies, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Dong H; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Ham JD; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Bobilev E; Division of Transplantation and Cellular Therapies, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., James S; Lurie Family Imaging Center, Center for Biomedical Imaging in Oncology, Dana Farber Cancer Institute, Boston, MA, USA., Cameron AB; Lurie Family Imaging Center, Center for Biomedical Imaging in Oncology, Dana Farber Cancer Institute, Boston, MA, USA., Nguyen QD; Lurie Family Imaging Center, Center for Biomedical Imaging in Oncology, Dana Farber Cancer Institute, Boston, MA, USA., Ganapathy S; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Chayawatto C; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Koreth J; Division of Transplantation and Cellular Therapies, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Paweletz CP; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Gokhale PC; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Barbie DA; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Division of Thoracic Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Matulonis UA; Division of Gynecologic Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Soiffer RJ; Division of Transplantation and Cellular Therapies, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Ritz J; Division of Transplantation and Cellular Therapies, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Porter RL; Division of Gynecologic Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Chen J; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Romee R; Division of Transplantation and Cellular Therapies, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.

المصدر: Science advances [Sci Adv] 2024 Jul 12; Vol. 10 (28), pp. eadn0881. Date of Electronic Publication: 2024 Jul 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

مواضيع طبية MeSH: Mesothelin* , Killer Cells, Natural*/immunology , Killer Cells, Natural*/metabolism , Ovarian Neoplasms*/metabolism , Ovarian Neoplasms*/pathology , Ovarian Neoplasms*/immunology , Ovarian Neoplasms*/therapy , Receptors, Chimeric Antigen*/metabolism , Receptors, Chimeric Antigen*/immunology , Receptors, Chimeric Antigen*/genetics , Xenograft Model Antitumor Assays*, Humans ; Animals ; Female ; Mice ; Cell Line, Tumor ; GPI-Linked Proteins/metabolism ; GPI-Linked Proteins/genetics ; Immunotherapy, Adoptive/methods ; Carcinoma, Ovarian Epithelial/metabolism ; Carcinoma, Ovarian Epithelial/pathology ; Carcinoma, Ovarian Epithelial/immunology ; Carcinoma, Ovarian Epithelial/therapy ; Immunologic Memory ; Protein Domains

المؤلفون: Mog BJ; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA., Marcou N; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., DiNapoli SR; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Pearlman AH; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Nichakawade TD; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.; Institute for NanoBioTechnology, Johns Hopkins University, 3400 N. Charles St., Baltimore, MD 21218, USA., Hwang MS; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Douglass J; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Hsiue EH; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Glavaris S; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Wright KM; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD 21287, USA., Konig MF; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Division of Rheumatology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA., Paul S; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Wyhs N; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Ge J; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Miller MS; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD 21287, USA., Azurmendi P; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD 21287, USA., Watson E; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Pardoll DM; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD 21287, USA., Gabelli SB; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD 21287, USA.; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Bettegowda C; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Papadopoulos N; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Kinzler KW; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD 21287, USA., Vogelstein B; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD 21287, USA.; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Zhou S; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD 21287, USA.

المصدر: Science translational medicine [Sci Transl Med] 2024 Jul 10; Vol. 16 (755), pp. eadg7123. Date of Electronic Publication: 2024 Jul 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, Chimeric Antigen*/metabolism , Receptors, Chimeric Antigen*/immunology , Receptors, Antigen, T-Cell*/metabolism , Receptors, Antigen, T-Cell*/immunology , Neoplasms*/immunology , Neoplasms*/therapy, Humans ; Animals ; Mice ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; Cell Line, Tumor ; Antigens, Neoplasm/immunology ; Antigens, Neoplasm/metabolism ; Signal Transduction

المؤلفون: Ledergor G; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA., Fan Z; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA., Wu K; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA.; Immunotherapy Integrated Research Center, Fred Hutchinson Cancer Center, Seattle, WA., McCarthy E; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA., Hyrenius-Wittsten A; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA.; Division of Clinical Genetics, Department of Laboratory Medicine, Lund University, Lund, Sweden., Starzinski A; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA., Chang H; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA., Bridge M; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA., Kwek S; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA., Cheung A; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA., Bylsma S; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA., Hansen E; Department of Orthopedic Surgery, University of California, San Francisco, San Francisco, CA., Wolf J; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA., Wong S; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA., Shah N; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA., Roybal KT; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA.; Parker Institute for Cancer Immunotherapy, San Francisco, CA., Martin T; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA., Ye CJ; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA.; Parker Institute for Cancer Immunotherapy, San Francisco, CA., Fong L; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA.; Immunotherapy Integrated Research Center, Fred Hutchinson Cancer Center, Seattle, WA.; Parker Institute for Cancer Immunotherapy, San Francisco, CA.

المصدر: Blood advances [Blood Adv] 2024 Jul 09; Vol. 8 (13), pp. 3562-3575.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE

مواضيع طبية MeSH: Multiple Myeloma*/therapy , Multiple Myeloma*/immunology , B-Cell Maturation Antigen*/metabolism , B-Cell Maturation Antigen*/immunology , Immunotherapy, Adoptive*/methods , Receptors, Chimeric Antigen*/immunology , Receptors, Chimeric Antigen*/metabolism , CD4-Positive T-Lymphocytes*/immunology , CD4-Positive T-Lymphocytes*/metabolism, Humans ; Recurrence ; Male ; Female ; T-Cell Exhaustion

المؤلفون: Deng T; Department of Research and Development, Hrain Biotechnology Co., Ltd., 1238 Zhangjiang Road, Pudong New District, Shanghai, China., Deng Y; Department of Research and Development, Hrain Biotechnology Co., Ltd., 1238 Zhangjiang Road, Pudong New District, Shanghai, China., Tsao ST; Department of Research and Development, Hrain Biotechnology Co., Ltd., 1238 Zhangjiang Road, Pudong New District, Shanghai, China., Xiong Q; Department of Research and Development, Hrain Biotechnology Co., Ltd., 1238 Zhangjiang Road, Pudong New District, Shanghai, China., Yao Y; Department of Research and Development, Hrain Biotechnology Co., Ltd., 1238 Zhangjiang Road, Pudong New District, Shanghai, China., Liu C; Regulatory Affairs Department, Hrain Biotechnology Co., Ltd., 1238 Zhangjiang Road, Pudong New District, Shanghai, China., Gu MY; Department of Research and Development, Hrain Biotechnology Co., Ltd., 1238 Zhangjiang Road, Pudong New District, Shanghai, China., Huang F; Department of Research and Development, Hrain Biotechnology Co., Ltd., 1238 Zhangjiang Road, Pudong New District, Shanghai, China. huangfei@dashengbio.com., Wang H; Department of Research and Development, Hrain Biotechnology Co., Ltd., 1238 Zhangjiang Road, Pudong New District, Shanghai, China. wanghaiying@dashengbio.com.

المصدر: Journal of translational medicine [J Transl Med] 2024 Jul 08; Vol. 22 (1), pp. 633. Date of Electronic Publication: 2024 Jul 08.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE

مواضيع طبية MeSH: Pancreatic Neoplasms*/therapy , Pancreatic Neoplasms*/immunology , Pancreatic Neoplasms*/pathology , Receptors, Chimeric Antigen*/metabolism , Receptors, Chimeric Antigen*/immunology , Immunotherapy, Adoptive*/methods , B7 Antigens*/metabolism , B7 Antigens*/immunology, Humans ; Animals ; Cell Line, Tumor ; Xenograft Model Antitumor Assays ; Mice ; Cell Proliferation ; T-Lymphocytes/immunology

المؤلفون: Maulana TI; Department of Microphysiological Systems, Institute of Biomedical Engineering, Faculty of Medicine, Eberhard Karls University-Tübingen, 72074 Tübingen, Germany; NMI Natural and Medical Sciences Institute at the University of Tübingen, 72770 Reutlingen, Germany., Teufel C; Department of Microphysiological Systems, Institute of Biomedical Engineering, Faculty of Medicine, Eberhard Karls University-Tübingen, 72074 Tübingen, Germany., Cipriano M; Department of Microphysiological Systems, Institute of Biomedical Engineering, Faculty of Medicine, Eberhard Karls University-Tübingen, 72074 Tübingen, Germany; 3R Center Tübingen for In Vitro Models and Alternatives to Animal Testing, 72074 Tübingen, Germany., Roosz J; NMI Natural and Medical Sciences Institute at the University of Tübingen, 72770 Reutlingen, Germany., Lazarevski L; Department of Microphysiological Systems, Institute of Biomedical Engineering, Faculty of Medicine, Eberhard Karls University-Tübingen, 72074 Tübingen, Germany., van den Hil FE; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden 2333 ZA, the Netherlands., Scheller L; Medizinische Klinik und Poliklinik II, Lehrstuhl für Zelluläre Immuntherapie, Universitätsklinikum Würzburg, 97078 Würzburg, Germany., Orlova V; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden 2333 ZA, the Netherlands., Koch A; Department of Women's Health Tübingen, Eberhard Karls University-Tübingen, 72076 Tübingen, Germany., Hudecek M; Medizinische Klinik und Poliklinik II, Lehrstuhl für Zelluläre Immuntherapie, Universitätsklinikum Würzburg, 97078 Würzburg, Germany; Fraunhofer-Institut für Zelltherapie und Immunologie IZI, Außenstelle Würzburg Zelluläre Immuntherapie, 97082 Würzburg, Germany., Alb M; Medizinische Klinik und Poliklinik II, Lehrstuhl für Zelluläre Immuntherapie, Universitätsklinikum Würzburg, 97078 Würzburg, Germany. Electronic address: alb_m@ukw.de., Loskill P; Department of Microphysiological Systems, Institute of Biomedical Engineering, Faculty of Medicine, Eberhard Karls University-Tübingen, 72074 Tübingen, Germany; NMI Natural and Medical Sciences Institute at the University of Tübingen, 72770 Reutlingen, Germany; 3R Center Tübingen for In Vitro Models and Alternatives to Animal Testing, 72074 Tübingen, Germany. Electronic address: peter.loskill@uni-tuebingen.de.

المصدر: Cell stem cell [Cell Stem Cell] 2024 Jul 05; Vol. 31 (7), pp. 989-1002.e9. Date of Electronic Publication: 2024 May 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101311472 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-9777 (Electronic) Linking ISSN: 18759777 NLM ISO Abbreviation: Cell Stem Cell Subsets: MEDLINE

مواضيع طبية MeSH: Breast Neoplasms*/pathology , Breast Neoplasms*/immunology , Receptors, Chimeric Antigen*/metabolism , Receptors, Chimeric Antigen*/immunology, Humans ; Female ; Immunotherapy, Adoptive/methods ; Tumor Microenvironment ; T-Lymphocytes/immunology ; Lab-On-A-Chip Devices ; Cell Line, Tumor ; Organoids/pathology

المؤلفون: Shen J; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin 300020, China. Electronic address: shenjun@ihcams.ac.cn., Lyu S; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin 300020, China., Xu Y; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin 300020, China., Zhang S; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin 300020, China; School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China., Li L; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin 300020, China; School of Medicine, Nankai University, Tianjin 300071, China., Li J; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin 300020, China; School of Basic Medical Sciences, Tianjin Medical University, Tianjin 300070, China., Mou J; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin 300020, China., Xie L; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin 300020, China., Tang K; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin 300020, China., Wen W; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin 300020, China., Peng X; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin 300020, China., Yang Y; Institute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China; Key Laboratory of Tumor Immunopathology, Ministry of Education of China, Chongqing 400038, China., Shi Y; Institute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China; Key Laboratory of Tumor Immunopathology, Ministry of Education of China, Chongqing 400038, China., Li X; School of Medicine, Sun Yat-sen University, Guangzhou 510006, China., Wang M; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin 300020, China., Li X; School of Medicine, Sun Yat-sen University, Guangzhou 510006, China. Electronic address: lixin253@mail.sysu.edu.cn., Wang J; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin 300020, China. Electronic address: wangjx@ihcams.ac.cn., Cheng T; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin 300020, China; Center for Stem Cell Medicine, Chinese Academy of Medical Sciences, Tianjin 300020, China; Department of Stem Cell & Regenerative Medicine, Peking Union Medical College, Tianjin 300020, China. Electronic address: chengtao@ihcams.ac.cn.

المصدر: Cell stem cell [Cell Stem Cell] 2024 Jul 05; Vol. 31 (7), pp. 1003-1019.e9. Date of Electronic Publication: 2024 May 08.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101311472 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-9777 (Electronic) Linking ISSN: 18759777 NLM ISO Abbreviation: Cell Stem Cell Subsets: MEDLINE

مواضيع طبية MeSH: Immunity, Innate* , Macrophages*/immunology , Receptors, Chimeric Antigen*/metabolism , Receptors, Chimeric Antigen*/immunology , Pluripotent Stem Cells*/cytology , Pluripotent Stem Cells*/immunology , Pluripotent Stem Cells*/metabolism, Humans ; Animals ; Mice ; Cell Differentiation ; Interferon-gamma/metabolism ; Neoplasms/immunology ; Neoplasms/therapy ; Neoplasms/pathology