المؤلفون: Reichard HA; Takeda California, Inc., 9625 Towne Centre Drive, San Diego, California 92121, United States., Schiffer HH; Takeda California, Inc., 9625 Towne Centre Drive, San Diego, California 92121, United States., Monenschein H; Takeda California, Inc., 9625 Towne Centre Drive, San Diego, California 92121, United States., Atienza JM; Takeda California, Inc., 9625 Towne Centre Drive, San Diego, California 92121, United States., Corbett G; Takeda Cambridge Ltd., 418 Cambridge Science Park, Cambridge, Cambridgeshire CB4 0PZ, U.K., Skaggs AW; Takeda California, Inc., 9625 Towne Centre Drive, San Diego, California 92121, United States., Collia DR; Takeda California, Inc., 9625 Towne Centre Drive, San Diego, California 92121, United States., Ray WJ; Takeda California, Inc., 9625 Towne Centre Drive, San Diego, California 92121, United States., Serrats J; Takeda California, Inc., 9625 Towne Centre Drive, San Diego, California 92121, United States., Bliesath J; Takeda California, Inc., 9625 Towne Centre Drive, San Diego, California 92121, United States., Kaushal N; Takeda California, Inc., 9625 Towne Centre Drive, San Diego, California 92121, United States., Lam BP; Takeda California, Inc., 9625 Towne Centre Drive, San Diego, California 92121, United States., Amador-Arjona A; Takeda California, Inc., 9625 Towne Centre Drive, San Diego, California 92121, United States., Rahbaek L; Takeda California, Inc., 9625 Towne Centre Drive, San Diego, California 92121, United States., McConn DJ; Takeda California, Inc., 9625 Towne Centre Drive, San Diego, California 92121, United States., Mulligan VJ; Takeda Cambridge Ltd., 418 Cambridge Science Park, Cambridge, Cambridgeshire CB4 0PZ, U.K., Brice N; Takeda Cambridge Ltd., 418 Cambridge Science Park, Cambridge, Cambridgeshire CB4 0PZ, U.K., Gaskin PLR; Takeda Cambridge Ltd., 418 Cambridge Science Park, Cambridge, Cambridgeshire CB4 0PZ, U.K., Cilia J; Takeda Cambridge Ltd., 418 Cambridge Science Park, Cambridge, Cambridgeshire CB4 0PZ, U.K., Hitchcock S; Takeda California, Inc., 9625 Towne Centre Drive, San Diego, California 92121, United States.

المصدر: Journal of medicinal chemistry [J Med Chem] 2021 Aug 12; Vol. 64 (15), pp. 11527-11542. Date of Electronic Publication: 2021 Jul 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Drug Discovery*, Nerve Tissue Proteins/*agonists , Receptors, G-Protein-Coupled/*agonists , Schizophrenia/*drug therapy, Animals ; Cell Line ; Dose-Response Relationship, Drug ; Humans ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Knockout ; Molecular Structure ; Nerve Tissue Proteins/deficiency ; Receptors, G-Protein-Coupled/deficiency ; Structure-Activity Relationship

المؤلفون: Sun H; Takeda California, 9625 Towne Centre Drive, San Diego, California 92121, United States., Monenschein H; Takeda California, 9625 Towne Centre Drive, San Diego, California 92121, United States., Schiffer HH; Takeda California, 9625 Towne Centre Drive, San Diego, California 92121, United States., Reichard HA; Takeda California, 9625 Towne Centre Drive, San Diego, California 92121, United States., Kikuchi S; Takeda California, 9625 Towne Centre Drive, San Diego, California 92121, United States., Hopkins M; Takeda California, 9625 Towne Centre Drive, San Diego, California 92121, United States., Macklin TK; Takeda California, 9625 Towne Centre Drive, San Diego, California 92121, United States., Hitchcock S; Takeda California, 9625 Towne Centre Drive, San Diego, California 92121, United States., Adams M; Takeda California, 9625 Towne Centre Drive, San Diego, California 92121, United States., Green J; Takeda California, 9625 Towne Centre Drive, San Diego, California 92121, United States., Brown J; Takeda California, 9625 Towne Centre Drive, San Diego, California 92121, United States., Murphy ST; Takeda California, 9625 Towne Centre Drive, San Diego, California 92121, United States., Kaushal N; Takeda California, 9625 Towne Centre Drive, San Diego, California 92121, United States., Collia DR; Takeda California, 9625 Towne Centre Drive, San Diego, California 92121, United States., Moore S; Takeda California, 9625 Towne Centre Drive, San Diego, California 92121, United States., Ray WJ; Takeda California, 9625 Towne Centre Drive, San Diego, California 92121, United States., English NM; Takeda California, 9625 Towne Centre Drive, San Diego, California 92121, United States., Carlton MBL; Cerevance Ltd, 418 Cambridge Science Park, Cambridge, U.K., Brice NL; Cerevance Ltd, 418 Cambridge Science Park, Cambridge, U.K.

المصدر: Journal of medicinal chemistry [J Med Chem] 2021 Jul 22; Vol. 64 (14), pp. 9875-9890. Date of Electronic Publication: 2021 Apr 16.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Drug Discovery*, Neuroprotective Agents/*pharmacology , Parkinson Disease/*drug therapy , Receptors, G-Protein-Coupled/*agonists, Animals ; Dose-Response Relationship, Drug ; Female ; Humans ; Molecular Structure ; Neuroprotective Agents/chemical synthesis ; Neuroprotective Agents/chemistry ; Parkinson Disease/metabolism ; Rats ; Rats, Sprague-Dawley ; Receptors, G-Protein-Coupled/metabolism ; Structure-Activity Relationship

المؤلفون: Greszler SN; Department of Chemistry, The Scripps Research Institute, Scripps Florida, Jupiter, Florida 33458, USA., Reichard HA, Micalizio GC

المصدر: Journal of the American Chemical Society [J Am Chem Soc] 2012 Feb 08; Vol. 134 (5), pp. 2766-74. Date of Electronic Publication: 2012 Jan 31.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE

مواضيع طبية MeSH: Indans/*chemical synthesis , Organometallic Compounds/*chemistry , Oxides/*chemistry , Titanium/*chemistry, Alkynes/chemistry ; Cyclization ; Indans/chemistry ; Molecular Structure ; Stereoisomerism

المؤلفون: Reichard HA; The Department of Chemistry, The Scripps Research Institute; Scripps-Florida, 130 Scripps Way #3A2, Jupiter, FL 33418, USA. ; Tel: 561 228 2463; micalizio@scripps.edu., Micalizio GC

المصدر: Chemical science [Chem Sci] 2011; Vol. 4 (2), pp. 573-589.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101545951 Publication Model: Print Cited Medium: Print ISSN: 2041-6520 (Print) Linking ISSN: 20416520 NLM ISO Abbreviation: Chem Sci Subsets: PubMed not MEDLINE

المؤلفون: Reichard HA; Department of Chemistry, The Scripps Research Institute Scripps-Florida 130 Scripps Way #3A2 Jupiter, FL 33458., McLaughlin M; Department of Chemistry, The Scripps Research Institute Scripps-Florida 130 Scripps Way #3A2 Jupiter, FL 33458., Chen MZ; Department of Chemistry, The Scripps Research Institute Scripps-Florida 130 Scripps Way #3A2 Jupiter, FL 33458., Micalizio GC; Department of Chemistry, The Scripps Research Institute Scripps-Florida 130 Scripps Way #3A2 Jupiter, FL 33458.

المصدر: European journal of organic chemistry [European J Org Chem] 2010 Jan; Vol. 2010 (3), pp. 391-409.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 9805750 Publication Model: Print Cited Medium: Print ISSN: 1434-193X (Print) Linking ISSN: 10990690 NLM ISO Abbreviation: European J Org Chem Subsets: PubMed not MEDLINE

المؤلفون: Reichard HA; Department of Chemistry, Yale University, 225 Prospect St., New Haven, CT 06520-8107, USA., Rieger JC, Micalizio GC

المصدر: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2008; Vol. 47 (41), pp. 7837-40.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print Cited Medium: Internet ISSN: 1521-3773 (Electronic) Linking ISSN: 14337851 NLM ISO Abbreviation: Angew Chem Int Ed Engl Subsets: MEDLINE

مواضيع طبية MeSH: Fatty Acids, Unsaturated/*chemical synthesis , Titanium/*chemistry, Alkenes/chemistry ; Fatty Acids, Unsaturated/chemistry ; Oxidation-Reduction

المؤلفون: Reichard HA; Department of Chemistry, Yale University, 225 Prospect Street, New Haven, CT 06520-8107, USA., Micalizio GC

المصدر: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2007; Vol. 46 (9), pp. 1440-3.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print Cited Medium: Print ISSN: 1433-7851 (Print) Linking ISSN: 14337851 NLM ISO Abbreviation: Angew Chem Int Ed Engl Subsets: MEDLINE

مواضيع طبية MeSH: Alkenes/*chemistry , Alkynes/*chemistry, Alkenes/chemical synthesis ; Catalysis ; Cyclization ; Heterocyclic Compounds/chemical synthesis ; Heterocyclic Compounds/chemistry ; Organometallic Compounds/chemistry ; Stereoisomerism