المؤلفون: Li J; Key Laboratory of Medical Electrophysiology of the Ministry of Education, Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan, China; Department of Cardiology, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, China., Luo F; Department of Cardiology, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, China., Liu X; Department of Anesthesiology, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, China., Ou X; Key Laboratory of Medical Electrophysiology of the Ministry of Education, Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan, China., Liu T; Key Laboratory of Medical Electrophysiology of the Ministry of Education, Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan, China., Huang Y; Department of Physiology, School of Basic Medical Sciences, Southwest Medical University, Luzhou, Sichuan, China., Liu W; Key Laboratory of Medical Electrophysiology of the Ministry of Education, Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan, China., Yang Y; Key Laboratory of Medical Electrophysiology of the Ministry of Education, Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan, China., Tan X; Key Laboratory of Medical Electrophysiology of the Ministry of Education, Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan, China; Department of Cardiology, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, China; Department of Physiology, School of Basic Medical Sciences, Southwest Medical University, Luzhou, Sichuan, China. Electronic address: tanxiaoqiu@swmu.edu.cn., Zhou S; Department of Anesthesiology, Ya'an People's Hospital, Ya'an, Sichuan, China. Electronic address: shuzhi0607@163.com., Chen T; Key Laboratory of Medical Electrophysiology of the Ministry of Education, Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan, China; Department of Cardiology, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, China. Electronic address: ctt@swmu.edu.cn.

المصدر: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2024 Aug 06; Vol. 720, pp. 150105. Date of Electronic Publication: 2024 May 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE

مواضيع طبية MeSH: Dexmedetomidine*/pharmacology , Ryanodine Receptor Calcium Release Channel*/metabolism , Ryanodine Receptor Calcium Release Channel*/genetics , Calcium*/metabolism , Arrhythmias, Cardiac*/metabolism , Arrhythmias, Cardiac*/drug therapy , Arrhythmias, Cardiac*/genetics, Animals ; Mice ; Membrane Potentials/drug effects ; Isoproterenol/pharmacology ; Tachycardia, Ventricular/metabolism ; Tachycardia, Ventricular/genetics ; Tachycardia, Ventricular/drug therapy ; Anti-Arrhythmia Agents/pharmacology ; Male ; Action Potentials/drug effects ; Mice, Inbred C57BL

SCR Disease Name: Polymorphic catecholergic ventricular tachycardia

المؤلفون: Dewenter M; Medical Faculty Heidelberg, Institute of Experimental Cardiology, Heidelberg University, Heidelberg, Germany.; Department of Internal Medicine 8, Heidelberg University Hospital, Heidelberg, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Sites Heidelberg/Mannheim and Göttingen, Heidelberg/Mannheim and Göttingen, Germany., Seitz T; DZHK (German Centre for Cardiovascular Research), Partner Sites Heidelberg/Mannheim and Göttingen, Heidelberg/Mannheim and Göttingen, Germany.; Department of Cardiology and Pneumology, University Medical Center Göttingen (UMG), Georg August University of Göttingen, Göttingen, Germany., Steinbrecher JH; DZHK (German Centre for Cardiovascular Research), Partner Sites Heidelberg/Mannheim and Göttingen, Heidelberg/Mannheim and Göttingen, Germany.; Department of Cardiology and Pneumology, University Medical Center Göttingen (UMG), Georg August University of Göttingen, Göttingen, Germany., Westenbrink BD; Department of Pharmacology, University of California San Diego, San Diego, CA, USA.; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Ling H; Department of Pharmacology, University of California San Diego, San Diego, CA, USA.; Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA., Lehnart SE; DZHK (German Centre for Cardiovascular Research), Partner Sites Heidelberg/Mannheim and Göttingen, Heidelberg/Mannheim and Göttingen, Germany.; Department of Cardiology and Pneumology, University Medical Center Göttingen (UMG), Georg August University of Göttingen, Göttingen, Germany., Wehrens XHT; Cardiovascular Research Institute and Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, USA., Backs J; Medical Faculty Heidelberg, Institute of Experimental Cardiology, Heidelberg University, Heidelberg, Germany.; Department of Internal Medicine 8, Heidelberg University Hospital, Heidelberg, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Sites Heidelberg/Mannheim and Göttingen, Heidelberg/Mannheim and Göttingen, Germany.; Molecular Medicine Partnership Unit, Heidelberg University & EMBL, Heidelberg, Germany.; Helmholtz Institute for Translational AngioCardioScience (HI-TAC)-a branch of the MDC at Heidelberg University, Heidelberg, Germany., Brown JH; Department of Pharmacology, University of California San Diego, San Diego, CA, USA., Maier LS; Department of Internal Medicine II, University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, Regensburg, Germany., Neef S; Department of Internal Medicine II, University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, Regensburg, Germany.

المصدر: ESC heart failure [ESC Heart Fail] 2024 Aug; Vol. 11 (4), pp. 2191-2199. Date of Electronic Publication: 2024 Apr 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: John Wiley & Sons Ltd on behalf of the European Society of Cardiology Country of Publication: England NLM ID: 101669191 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2055-5822 (Electronic) Linking ISSN: 20555822 NLM ISO Abbreviation: ESC Heart Fail Subsets: MEDLINE

مواضيع طبية MeSH: Heart Failure*/metabolism , Sarcoplasmic Reticulum*/metabolism , Calcium-Calmodulin-Dependent Protein Kinase Type 2*/metabolism , Calcium-Calmodulin-Dependent Protein Kinase Type 2*/genetics , Ryanodine Receptor Calcium Release Channel*/metabolism , Ryanodine Receptor Calcium Release Channel*/genetics , Calcium*/metabolism , Myocytes, Cardiac*/metabolism , Myocytes, Cardiac*/pathology , Mice, Transgenic*, Animals ; Mice ; Phosphorylation ; Disease Models, Animal ; Calcium Signaling/physiology ; Chronic Disease

المؤلفون: Naumenko N; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland., Koivumäki JT; BioMediTech, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Lunko O; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland., Tuomainen T; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland., Leigh R; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland., Rabiee M; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland., Laurila J; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland., Oksanen M; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland., Lehtonen S; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland; Neuroscience Center, Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland., Koistinaho J; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland; Neuroscience Center, Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland., Tavi P; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland. Electronic address: pasi.tavi@uef.fi.

المصدر: Journal of molecular and cellular cardiology [J Mol Cell Cardiol] 2024 Aug; Vol. 193, pp. 78-87. Date of Electronic Publication: 2024 Jun 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Academic Press Country of Publication: England NLM ID: 0262322 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-8584 (Electronic) Linking ISSN: 00222828 NLM ISO Abbreviation: J Mol Cell Cardiol Subsets: MEDLINE

مواضيع طبية MeSH: Induced Pluripotent Stem Cells*/metabolism , Myocytes, Cardiac*/metabolism , Presenilin-1*/genetics , Presenilin-1*/metabolism , Sarcoplasmic Reticulum*/metabolism , Calcium*/metabolism , Mutation* , Calcium Signaling* , Ryanodine Receptor Calcium Release Channel*/metabolism , Ryanodine Receptor Calcium Release Channel*/genetics, Humans

المؤلفون: Pavlaki N; Institute of Experimental Cardiovascular Research, University Medical Center Hamburg-Eppendorf, Martinistr. 52, D-20246 Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, Martinistr. 52, D-20246 Hamburg, Germany., Froese A; Institute of Experimental Cardiovascular Research, University Medical Center Hamburg-Eppendorf, Martinistr. 52, D-20246 Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, Martinistr. 52, D-20246 Hamburg, Germany., Li W; Institute of Pharmacology and Toxicology, Technical University of Dresden, Dresden, Germany., De Jong KA; Institute of Experimental Cardiovascular Research, University Medical Center Hamburg-Eppendorf, Martinistr. 52, D-20246 Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, Martinistr. 52, D-20246 Hamburg, Germany., Geertz B; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, Martinistr. 52, D-20246 Hamburg, Germany.; Institute of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, D-20246 Hamburg, Germany., Subramanian H; Institute of Experimental Cardiovascular Research, University Medical Center Hamburg-Eppendorf, Martinistr. 52, D-20246 Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, Martinistr. 52, D-20246 Hamburg, Germany., Mohagaonkar S; Institute of Experimental Cardiovascular Research, University Medical Center Hamburg-Eppendorf, Martinistr. 52, D-20246 Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, Martinistr. 52, D-20246 Hamburg, Germany., Luo X; Institute of Pharmacology and Toxicology, Technical University of Dresden, Dresden, Germany., Schubert M; Institute of Pharmacology and Toxicology, Technical University of Dresden, Dresden, Germany., Wiegmann R; Institute of Experimental Cardiovascular Research, University Medical Center Hamburg-Eppendorf, Martinistr. 52, D-20246 Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, Martinistr. 52, D-20246 Hamburg, Germany.; Department of Anesthesiology, Center of Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Margaria JP; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino, Torino, Italy.; Cystic Kidney Disorders Unit, Division of Genetics and Cell Biology, Università Vita-Salute San Raffaele, Milan, Italy., Ghigo A; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino, Torino, Italy., Kämmerer S; Institute of Pharmacology and Toxicology, Technical University of Dresden, Dresden, Germany., Hirsch E; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino, Torino, Italy., El-Armouche A; Institute of Pharmacology and Toxicology, Technical University of Dresden, Dresden, Germany., Guan K; Institute of Pharmacology and Toxicology, Technical University of Dresden, Dresden, Germany., Nikolaev VO; Institute of Experimental Cardiovascular Research, University Medical Center Hamburg-Eppendorf, Martinistr. 52, D-20246 Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, Martinistr. 52, D-20246 Hamburg, Germany.

المصدر: Cardiovascular research [Cardiovasc Res] 2024 Jul 31; Vol. 120 (9), pp. 1011-1023.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford Journals Country of Publication: England NLM ID: 0077427 Publication Model: Print Cited Medium: Internet ISSN: 1755-3245 (Electronic) Linking ISSN: 00086363 NLM ISO Abbreviation: Cardiovasc Res Subsets: MEDLINE

مواضيع طبية MeSH: Cyclic AMP*/metabolism , Heart Failure*/enzymology , Heart Failure*/genetics , Heart Failure*/therapy , Heart Failure*/physiopathology , Heart Failure*/metabolism , Genetic Therapy* , Cyclic Nucleotide Phosphodiesterases, Type 2*/metabolism , Cyclic Nucleotide Phosphodiesterases, Type 2*/genetics , Myocytes, Cardiac*/enzymology , Myocytes, Cardiac*/metabolism , Myocytes, Cardiac*/pathology , Cyclic Nucleotide Phosphodiesterases, Type 4*/metabolism , Cyclic Nucleotide Phosphodiesterases, Type 4*/genetics , Disease Models, Animal* , Ryanodine Receptor Calcium Release Channel*/metabolism , Ryanodine Receptor Calcium Release Channel*/genetics, Animals ; Humans ; Mice, Inbred C57BL ; Male ; Arrhythmias, Cardiac/enzymology ; Arrhythmias, Cardiac/genetics ; Arrhythmias, Cardiac/metabolism ; Arrhythmias, Cardiac/physiopathology ; Arrhythmias, Cardiac/prevention & control ; Ventricular Remodeling ; Induced Pluripotent Stem Cells/enzymology ; Induced Pluripotent Stem Cells/metabolism ; Second Messenger Systems/drug effects ; Ventricular Function, Left ; Calcium Signaling ; Phosphorylation ; Heart Rate

المؤلفون: Chen J; College of Basic Medicine, Hebei University of Chinese Medicine, No.3 Xingyuan Road, Shijiazhuang, 050200, Hebei, China.; Shenzhen Hospital of Guangzhou University of Chinese Medicine, Shenzhen, 518034, Guangdong, China., Bao J; College of Basic Medicine, Hebei University of Chinese Medicine, No.3 Xingyuan Road, Shijiazhuang, 050200, Hebei, China., Jiang X; College of Basic Medicine, Hebei University of Chinese Medicine, No.3 Xingyuan Road, Shijiazhuang, 050200, Hebei, China., Yu W; College of Basic Medicine, Hebei University of Chinese Medicine, No.3 Xingyuan Road, Shijiazhuang, 050200, Hebei, China., Han Y; College of Basic Medicine, Hebei University of Chinese Medicine, No.3 Xingyuan Road, Shijiazhuang, 050200, Hebei, China., Zhang X; College of Basic Medicine, Hebei University of Chinese Medicine, No.3 Xingyuan Road, Shijiazhuang, 050200, Hebei, China., Zhang Y; College of Nursing, Hebei University of Chinese Medicine, No.3 Xingyuan Road, Shijiazhuang, 050200, Hebei, China. yingzhang@hebcm.edu.cn.; Hebei Key Laboratory of Health Care with Traditional Chinese Medicine, Shijiazhuang, 050200, Hebei, China. yingzhang@hebcm.edu.cn., Deng G; College of Basic Medicine, Hebei University of Chinese Medicine, No.3 Xingyuan Road, Shijiazhuang, 050200, Hebei, China. dengguoxing@hebcm.edu.cn.

المصدر: Scientific reports [Sci Rep] 2024 Jul 30; Vol. 14 (1), pp. 17497. Date of Electronic Publication: 2024 Jul 30.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Saponins*/pharmacology , Triterpenes*/pharmacology , Ryanodine Receptor Calcium Release Channel*/metabolism , Ryanodine Receptor Calcium Release Channel*/genetics , Reperfusion Injury*/metabolism , Reperfusion Injury*/drug therapy , Neuroprotective Agents*/pharmacology , Apoptosis*/drug effects, Animals ; Mice ; Male ; Rats ; PC12 Cells ; src-Family Kinases/metabolism ; Brain/metabolism ; Brain/drug effects ; Brain/pathology ; Infarction, Middle Cerebral Artery/drug therapy ; Infarction, Middle Cerebral Artery/metabolism ; Disease Models, Animal

المؤلفون: Thorpe MP; Department of Chemistry and Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37235, United States., Blackwell DJ; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37235, United States., Knollmann BC; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37235, United States., Johnston JN; Department of Chemistry and Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37235, United States.

المصدر: Journal of medicinal chemistry [J Med Chem] 2024 Jul 25; Vol. 67 (14), pp. 12205-12220. Date of Electronic Publication: 2024 Jul 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Depsipeptides*/chemistry , Depsipeptides*/pharmacology , Depsipeptides*/chemical synthesis , Ryanodine Receptor Calcium Release Channel*/metabolism , Ryanodine Receptor Calcium Release Channel*/chemistry , Biological Products*/chemistry , Biological Products*/pharmacology , Biological Products*/chemical synthesis , Anti-Arrhythmia Agents*/pharmacology , Anti-Arrhythmia Agents*/chemistry , Anti-Arrhythmia Agents*/chemical synthesis, Structure-Activity Relationship ; Humans ; Animals ; Stereoisomerism

المؤلفون: Feng C; Guang'anmen Hospital of China Academy of Chinese Medical Sciences, No 5. Beixiange Street, Beijing, 100053, China., Song J; International Campus, Zhejiang University-University of Edinburgh Institute, Zhejiang University, Haining, China., Deng L; Guang'anmen Hospital of China Academy of Chinese Medical Sciences, No 5. Beixiange Street, Beijing, 100053, China., Zhang J; Jingmen Hospital of Traditional Chinese Medicine, Jingmen, China., Lian X; Guang'anmen Hospital of China Academy of Chinese Medical Sciences, No 5. Beixiange Street, Beijing, 100053, China., Zhen Z; Guang'anmen Hospital of China Academy of Chinese Medical Sciences, No 5. Beixiange Street, Beijing, 100053, China., Liu J; Guang'anmen Hospital of China Academy of Chinese Medical Sciences, No 5. Beixiange Street, Beijing, 100053, China. Gamyy2082@163.com.

المصدر: BMC cardiovascular disorders [BMC Cardiovasc Disord] 2024 Jul 03; Vol. 24 (1), pp. 333. Date of Electronic Publication: 2024 Jul 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100968539 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2261 (Electronic) Linking ISSN: 14712261 NLM ISO Abbreviation: BMC Cardiovasc Disord Subsets: MEDLINE

مواضيع طبية MeSH: Rats, Sprague-Dawley* , Diabetes Mellitus, Experimental*/drug therapy , Oxidative Stress*/drug effects , Ryanodine Receptor Calcium Release Channel*/metabolism , Ryanodine Receptor Calcium Release Channel*/drug effects , Ginsenosides*/pharmacology , Diabetic Cardiomyopathies*/metabolism , Diabetic Cardiomyopathies*/drug therapy , Diabetic Cardiomyopathies*/pathology , Diabetic Cardiomyopathies*/physiopathology , Diabetic Cardiomyopathies*/etiology , Apoptosis*/drug effects , Streptozocin* , Antioxidants*/pharmacology , Myocytes, Cardiac*/drug effects , Myocytes, Cardiac*/pathology , Myocytes, Cardiac*/metabolism, Animals ; Male ; Phosphorylation ; Myocardium/pathology ; Myocardium/metabolism ; Insulin ; Malondialdehyde/metabolism

المؤلفون: Weninger G; Department of Physiology and Cellular Biophysics, Center for Molecular Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY 10032., Miotto MC; Department of Physiology and Cellular Biophysics, Center for Molecular Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY 10032., Tchagou C; Department of Physiology and Cellular Biophysics, Center for Molecular Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY 10032., Reiken S; Department of Physiology and Cellular Biophysics, Center for Molecular Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY 10032., Dridi H; Department of Physiology and Cellular Biophysics, Center for Molecular Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY 10032., Brandenburg S; Department of Cardiology and Pneumology, Cellular Biophysics and Translational Cardiology Section, Heart Research Center Göttingen, University Medical Center Göttingen, 37075 Göttingen, Germany.; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC 2067), University of Göttingen, 37075 Göttingen, Germany., Riedemann GC; Department of Cardiology and Pneumology, Cellular Biophysics and Translational Cardiology Section, Heart Research Center Göttingen, University Medical Center Göttingen, 37075 Göttingen, Germany., Yuan Q; Department of Physiology and Cellular Biophysics, Center for Molecular Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY 10032., Liu Y; Department of Physiology and Cellular Biophysics, Center for Molecular Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY 10032., Chang A; Department of Physiology and Cellular Biophysics, Center for Molecular Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY 10032., Wronska A; Department of Physiology and Cellular Biophysics, Center for Molecular Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY 10032., Lehnart SE; Department of Cardiology and Pneumology, Cellular Biophysics and Translational Cardiology Section, Heart Research Center Göttingen, University Medical Center Göttingen, 37075 Göttingen, Germany.; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC 2067), University of Göttingen, 37075 Göttingen, Germany., Marks AR; Department of Physiology and Cellular Biophysics, Center for Molecular Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY 10032.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Jul 02; Vol. 121 (27), pp. e2400497121. Date of Electronic Publication: 2024 Jun 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Ryanodine Receptor Calcium Release Channel*/metabolism , Ryanodine Receptor Calcium Release Channel*/chemistry , S100 Proteins*/metabolism , S100 Proteins*/chemistry , Calcium*/metabolism , Cryoelectron Microscopy*, Animals ; Protein Binding ; Binding Sites ; Models, Molecular ; Protein Conformation ; Humans

المؤلفون: Rebbeck RT; Department of Biochemistry, Molecular Biology & Biophysics, University of Minnesota, Minneapolis, MN, USA. rrebbeck@umn.edu., Svensson B; Department of Biochemistry, Molecular Biology & Biophysics, University of Minnesota, Minneapolis, MN, USA., Zhang J; Department of Biochemistry, Molecular Biology & Biophysics, University of Minnesota, Minneapolis, MN, USA., Samsó M; Department of Physiology and Biophysics, Virginia Commonwealth University, Richmond, VA, USA., Thomas DD; Department of Biochemistry, Molecular Biology & Biophysics, University of Minnesota, Minneapolis, MN, USA., Bers DM; Department of Pharmacology, University of California at Davis, Davis, CA, USA., Cornea RL; Department of Biochemistry, Molecular Biology & Biophysics, University of Minnesota, Minneapolis, MN, USA. corne002@umn.edu.

المصدر: Nature communications [Nat Commun] 2024 Jun 15; Vol. 15 (1), pp. 5120. Date of Electronic Publication: 2024 Jun 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Ryanodine Receptor Calcium Release Channel*/metabolism , Ryanodine Receptor Calcium Release Channel*/chemistry , Calmodulin*/metabolism , Calmodulin*/chemistry , Calcium*/metabolism , Myocardium*/metabolism , Muscle, Skeletal*/metabolism , Fluorescence Resonance Energy Transfer*, Kinetics ; Animals ; Humans ; Protein Conformation ; Protein Binding ; Sarcoplasmic Reticulum/metabolism

المؤلفون: Gao Y; Department of Cardiology, China-Japan Union Hospital of Jilin University, Changchun, China.; Jilin Provincial International Joint Research Center of Cardiovascular Disease Precision Medicine, Changchun, China.; Jilin Provincial Precision Medicine Key Laboratory for Cardiovascular Genetic Diagnosis, Changchun, China., Li S; Department of Cardiology, China-Japan Union Hospital of Jilin University, Changchun, China., Liu X; Department of Cardiology, China-Japan Union Hospital of Jilin University, Changchun, China.; Jilin Provincial International Joint Research Center of Cardiovascular Disease Precision Medicine, Changchun, China.; Jilin Provincial Precision Medicine Key Laboratory for Cardiovascular Genetic Diagnosis, Changchun, China., Si D; Department of Cardiology, China-Japan Union Hospital of Jilin University, Changchun, China.; Jilin Provincial International Joint Research Center of Cardiovascular Disease Precision Medicine, Changchun, China.; Jilin Provincial Precision Medicine Key Laboratory for Cardiovascular Genetic Diagnosis, Changchun, China., Chen W; Department of Cardiology, China-Japan Union Hospital of Jilin University, Changchun, China.; Jilin Provincial International Joint Research Center of Cardiovascular Disease Precision Medicine, Changchun, China.; Jilin Provincial Precision Medicine Key Laboratory for Cardiovascular Genetic Diagnosis, Changchun, China., Yang F; Guangdong Laboratory Animals Monitoring Institute, Guangzhou, China., Sun H; Department of Cardiology, China-Japan Union Hospital of Jilin University, Changchun, China. sunhuan0404@jlu.edu.cn.; Jilin Provincial International Joint Research Center of Cardiovascular Disease Precision Medicine, Changchun, China. sunhuan0404@jlu.edu.cn.; Jilin Provincial Precision Medicine Key Laboratory for Cardiovascular Genetic Diagnosis, Changchun, China. sunhuan0404@jlu.edu.cn., Yang P; Department of Cardiology, China-Japan Union Hospital of Jilin University, Changchun, China. pyang@jlu.edu.cn.; Jilin Provincial International Joint Research Center of Cardiovascular Disease Precision Medicine, Changchun, China. pyang@jlu.edu.cn.; Jilin Provincial Precision Medicine Key Laboratory for Cardiovascular Genetic Diagnosis, Changchun, China. pyang@jlu.edu.cn.

المصدر: Journal of cardiovascular translational research [J Cardiovasc Transl Res] 2024 Jun; Vol. 17 (3), pp. 481-495. Date of Electronic Publication: 2024 Apr 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Country of Publication: United States NLM ID: 101468585 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-5395 (Electronic) Linking ISSN: 19375387 NLM ISO Abbreviation: J Cardiovasc Transl Res Subsets: MEDLINE

مواضيع طبية MeSH: Signal Transduction*/drug effects , Tumor Necrosis Factor-alpha*/metabolism , Ryanodine Receptor Calcium Release Channel*/metabolism , Ryanodine Receptor Calcium Release Channel*/genetics , Ryanodine Receptor Calcium Release Channel*/drug effects , Calcineurin*/metabolism , NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism , Mice, Inbred C57BL* , Myocytes, Cardiac*/drug effects , Myocytes, Cardiac*/metabolism , Myocytes, Cardiac*/pathology , Disease Models, Animal* , NF-kappa B*/metabolism , Down-Regulation* , Dantrolene*/pharmacology, Animals ; Male ; Calcineurin Inhibitors/pharmacology ; NFATC Transcription Factors/metabolism ; Cells, Cultured ; Cardiomegaly/metabolism ; Cardiomegaly/prevention & control ; Cardiomegaly/pathology ; Cardiomegaly/drug therapy ; Rats, Sprague-Dawley ; Rats ; Hypertrophy, Left Ventricular/prevention & control ; Hypertrophy, Left Ventricular/metabolism ; Hypertrophy, Left Ventricular/pathology ; Hypertrophy, Left Ventricular/physiopathology