لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

المساهمون: Remsberg, Jr, L

المصدر: Other Information: Orig. Receipt Date: 31-DEC-63

وصف الملف: Medium: X; Size: Pages: 42

URL الوصول: http://www.osti.gov/scitech/biblio/4779606

المؤلفون: Liu Z; Department of Chemistry, Scripps Research, La Jolla, California 92037, United States., Remsberg JR; Department of Chemistry, Scripps Research, La Jolla, California 92037, United States., Li H; Department of Chemistry, Scripps Research, La Jolla, California 92037, United States., Njomen E; Department of Chemistry, Scripps Research, La Jolla, California 92037, United States., DeMeester KE; Department of Chemistry, Scripps Research, La Jolla, California 92037, United States., Tao Y; Department of Chemistry, Scripps Research, La Jolla, California 92037, United States., Xia G; Department of Chemistry, Scripps Research, La Jolla, California 92037, United States., Hayward RE; Department of Chemistry, Scripps Research, La Jolla, California 92037, United States., Yoo M; Department of Chemistry, Scripps Research, La Jolla, California 92037, United States., Nguyen T; Vividion Therapeutics, San Diego, California 92121, United States., Simon GM; Vividion Therapeutics, San Diego, California 92121, United States., Schreiber SL; Chemical Biology and Therapeutics Science Program, Broad Institute, Cambridge, Massachusetts 02142, United States.; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, United States., Melillo B; Department of Chemistry, Scripps Research, La Jolla, California 92037, United States.; Chemical Biology and Therapeutics Science Program, Broad Institute, Cambridge, Massachusetts 02142, United States., Cravatt BF; Department of Chemistry, Scripps Research, La Jolla, California 92037, United States.; Vividion Therapeutics, San Diego, California 92121, United States.

المصدر: Journal of the American Chemical Society [J Am Chem Soc] 2024 Apr 17; Vol. 146 (15), pp. 10393-10406. Date of Electronic Publication: 2024 Apr 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE

مواضيع طبية MeSH: Acrylamide* , Diterpenes* , Phenanthrenes*, Humans ; Cysteine/chemistry ; Proteomics ; Epoxy Compounds

المؤلفون: Won SJ, Zhang Y, Reinhardt CJ, MacRae NS, DeMeester KE, Njomen E, Hargis LM, Remsberg JR, Melillo B, Cravatt BF, Erb MA

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2024 Mar 21. Date of Electronic Publication: 2024 Mar 21.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Tao Y; Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550N. Torrey Pines Road, La Jolla, CA-92307, USA., Felber JG; Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550N. Torrey Pines Road, La Jolla, CA-92307, USA.; LMU Munich, Department of Pharmacy, Butenandtstr. 5-13, 81377, Munich, Germany., Zou Z; Department of Chemistry, The University of Chicago, 929 East 57th Street, GCIS E319B, Chicago, IL-60637, USA., Njomen E; Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550N. Torrey Pines Road, La Jolla, CA-92307, USA., Remsberg JR; Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550N. Torrey Pines Road, La Jolla, CA-92307, USA.; Current address: Belharra Therapeutics, 3985 Sorrento Valley Blvd Suite C, San Diego, CA-92121, USA., Ogasawara D; Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550N. Torrey Pines Road, La Jolla, CA-92307, USA., Ye C; Department of Chemistry, The University of Chicago, 929 East 57th Street, GCIS E319B, Chicago, IL-60637, USA., Melillo B; Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550N. Torrey Pines Road, La Jolla, CA-92307, USA.; Chemical Biology and Therapeutics Science Program, Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA-02142, USA., Schreiber SL; Chemical Biology and Therapeutics Science Program, Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA-02142, USA.; Harvard University, Department of Chemistry and Chemical Biology, 12 Oxford Street, MA-02138, Cambridge, USA., He C; Department of Chemistry, The University of Chicago, 929 East 57th Street, GCIS E319B, Chicago, IL-60637, USA.; Howard Hughes Medical Institute, The University of Chicago, 929 East 57th Street, GCIS E319B, Chicago, IL-60637, USA., Remillard D; Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550N. Torrey Pines Road, La Jolla, CA-92307, USA.; Current address: Novartis, 10675 John Jay Hopkins Dr, San Diego, CA-92121, USA., Cravatt BF; Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550N. Torrey Pines Road, La Jolla, CA-92307, USA.

المصدر: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2023 Dec 18; Vol. 62 (51), pp. e202311924. Date of Electronic Publication: 2023 Nov 14.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3773 (Electronic) Linking ISSN: 14337851 NLM ISO Abbreviation: Angew Chem Int Ed Engl Subsets: MEDLINE

مواضيع طبية MeSH: Azetidines* , Methyltransferases*/antagonists & inhibitors , tRNA Methyltransferases*/antagonists & inhibitors , Enzyme Inhibitors*/chemistry , Enzyme Inhibitors*/pharmacology, Humans ; Acrylamides ; Cysteine/metabolism ; Methylation ; Proteomics ; RNA, Transfer/chemistry

المؤلفون: Li H; Department of Chemistry, Scripps Research, La Jolla, CA, USA. haoxinli@scripps.edu., Ma T; Department of Molecular Biology, School of Biological Sciences, University of California San Diego, La Jolla, CA, USA., Remsberg JR; Department of Chemistry, Scripps Research, La Jolla, CA, USA., Won SJ; Department of Chemistry, Scripps Research, La Jolla, CA, USA., DeMeester KE; Department of Chemistry, Scripps Research, La Jolla, CA, USA., Njomen E; Department of Chemistry, Scripps Research, La Jolla, CA, USA., Ogasawara D; Department of Chemistry, Scripps Research, La Jolla, CA, USA., Zhao KT; Merkin Institute of Transformative Technologies in Healthcare, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.; Howard Hughes Medical Institute, Cambridge, MA, USA., Huang TP; Merkin Institute of Transformative Technologies in Healthcare, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.; Howard Hughes Medical Institute, Cambridge, MA, USA., Lu B; Vividion Therapeutics, San Diego, CA, USA., Simon GM; Vividion Therapeutics, San Diego, CA, USA., Melillo B; Department of Chemistry, Scripps Research, La Jolla, CA, USA., Schreiber SL; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Lykke-Andersen J; Department of Molecular Biology, School of Biological Sciences, University of California San Diego, La Jolla, CA, USA., Liu DR; Merkin Institute of Transformative Technologies in Healthcare, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.; Howard Hughes Medical Institute, Cambridge, MA, USA., Cravatt BF; Department of Chemistry, Scripps Research, La Jolla, CA, USA. cravatt@scripps.edu.

المصدر: Nature chemical biology [Nat Chem Biol] 2023 Nov; Vol. 19 (11), pp. 1320-1330. Date of Electronic Publication: 2023 Oct 02.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Cysteine*/chemistry , Neoplasms*/genetics, Humans ; Proteomics ; Gene Editing ; Proteome/chemistry ; Nuclear Proteins

المؤلفون: Kathman SG; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA. skathman@scripps.edu., Koo SJ; Molecular and Cellular Pharmacology, Discovery Technologies and Molecular Pharmacology, Janssen Research and Development, Beerse, Belgium., Lindsey GL; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Her HL; Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA, USA., Blue SM; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA., Li H; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Jaensch S; High Dimensional and Computational Biology, Discovery Technologies and Molecular Pharmacology, Janssen Research and Development, Beerse, Belgium., Remsberg JR; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Ahn K; Molecular and Cellular Pharmacology, Discovery Technologies and Molecular Pharmacology, Janssen Research and Development, Spring House, PA, USA. kayahn2@gmail.com., Yeo GW; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA. geneyeo@ucsd.edu., Ghosh B; Discovery Chemistry, Janssen Research and Development, Spring House, PA, USA. bghosh7@its.jnj.com., Cravatt BF; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA. cravatt@scripps.edu.

المصدر: Nature chemical biology [Nat Chem Biol] 2023 Jul; Vol. 19 (7), pp. 825-836. Date of Electronic Publication: 2023 Mar 02.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: DNA-Binding Proteins*/metabolism , Transcriptome*, Male ; Humans ; RNA-Binding Proteins/chemistry ; RNA

المؤلفون: Lazear MR; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA., Remsberg JR; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA. Electronic address: remsberg@scripps.edu., Jaeger MG; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA., Rothamel K; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA., Her HL; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA., DeMeester KE; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA., Njomen E; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA., Hogg SJ; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA., Rahman J; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA., Whitby LR; Vividion Therapeutics, 5820 Nancy Ridge Drive, San Diego, CA 92121, USA., Won SJ; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA., Schafroth MA; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA., Ogasawara D; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA., Yokoyama M; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA., Lindsey GL; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA., Li H; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA., Germain J; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA., Barbas S; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA., Vaughan J; Clayton Foundation Laboratories for Peptide Biology, The Salk Institute for Biological Studies, La Jolla, CA, USA., Hanigan TW; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA., Vartabedian VF; Department of Immunology and Microbiology, Scripps Research, La Jolla, CA 92037, USA., Reinhardt CJ; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA., Dix MM; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA., Koo SJ; Molecular and Cellular Pharmacology, Discovery Technologies and Molecular Pharmacology, Janssen Research and Development, Turnhoutseweg 30, 2340 Beerse, Belgium., Heo I; Molecular and Cellular Pharmacology, Discovery Technologies and Molecular Pharmacology, Janssen Research and Development, Turnhoutseweg 30, 2340 Beerse, Belgium., Teijaro JR; Department of Immunology and Microbiology, Scripps Research, La Jolla, CA 92037, USA., Simon GM; Vividion Therapeutics, 5820 Nancy Ridge Drive, San Diego, CA 92121, USA., Ghosh B; Discovery Chemistry, Janssen Research & Development, Spring House, PA 19477, USA., Abdel-Wahab O; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA., Ahn K; Molecular and Cellular Pharmacology, Discovery Technologies and Molecular Pharmacology, Janssen Research and Development, Spring House, PA 19477, USA., Saghatelian A; Clayton Foundation Laboratories for Peptide Biology, The Salk Institute for Biological Studies, La Jolla, CA, USA., Melillo B; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA; Chemical Biology and Therapeutics Science Program, Broad Institute, Cambridge, MA 02142, USA., Schreiber SL; Chemical Biology and Therapeutics Science Program, Broad Institute, Cambridge, MA 02142, USA; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA., Yeo GW; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA., Cravatt BF; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA. Electronic address: cravatt@scripps.edu.

المصدر: Molecular cell [Mol Cell] 2023 May 18; Vol. 83 (10), pp. 1725-1742.e12. Date of Electronic Publication: 2023 Apr 20.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE

مواضيع طبية MeSH: Proteomics*/methods , Transcription Factors*, Humans ; Cysteine/metabolism ; Ligands

المؤلفون: Remsberg JR; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Suciu RM; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Zambetti NA; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA., Hanigan TW; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Firestone AJ; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA., Inguva A; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA., Long A; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA., Ngo N; Lundbeck La Jolla Research Center, Inc., San Diego, CA, USA., Lum KM; Lundbeck La Jolla Research Center, Inc., San Diego, CA, USA., Henry CL; Lundbeck La Jolla Research Center, Inc., San Diego, CA, USA., Richardson SK; Department of Chemistry, University of Connecticut, Storrs, CT, USA., Predovic M; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA., Huang B; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA., Dix MM; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Howell AR; Department of Chemistry, University of Connecticut, Storrs, CT, USA., Niphakis MJ; Lundbeck La Jolla Research Center, Inc., San Diego, CA, USA. MIIP@lundbeck.com., Shannon K; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA. Kevin.Shannon@ucsf.edu.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA. Kevin.Shannon@ucsf.edu., Cravatt BF; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA. cravatt@scripps.edu.

المصدر: Nature chemical biology [Nat Chem Biol] 2021 Aug; Vol. 17 (8), pp. 856-864. Date of Electronic Publication: 2021 Apr 29.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Cell Membrane/*metabolism , Hydrolases/*metabolism , Leukemia, Myeloid, Acute/*metabolism , Leukemia, Promyelocytic, Acute/*metabolism , ras Proteins/*metabolism, Cell Proliferation ; Cells, Cultured ; Humans ; Leukemia, Myeloid, Acute/pathology ; Leukemia, Promyelocytic, Acute/pathology ; Lipoylation ; Microsomes, Liver/chemistry ; Microsomes, Liver/metabolism ; Molecular Structure