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1دورية أكاديمية
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المؤلفون: Galindo León, Laura Daniela
المصدر: Séneca: repositorio Uniandes
Universidad de los Andes
instacron:Universidad de los Andesمصطلحات موضوعية: Losartán, Doxorrubicina, Terapia combinatoria, Reposicionamiento de medicamentos, Química, Metformina, Citometría de flujo
وصف الملف: 54 páginas; application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______3056::eb06b7164503e5bcc43b82f742c72b7a
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المؤلفون: Marina Esteban-Medina, Carlos Loucera, Matias M. Falco, Joaquín Dopazo, Maria Peña-Chilet, Kinza Rian
المساهمون: [Loucera,C, Esteban-Medina,M, Rian,K, Falco,MM, Dopazo,J, Peña-Chilet,M] Clinical Bioinformatics Area. Fundación Progreso y Salud (FPS). CDCA, Hospital Virgen del Rocio, Sevilla, Spain. [Loucera,C, Peña-Chilet,M] 2Computational Systems Medicine, Institute of Biomedicine of Seville (IBIS), Hospital Virgen del Rocio, Sevilla, Spain. [Falco,MM, Peña-Chilet,M] 3Bioinformatics in Rare Diseases (BiER). Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), FPS, Hospital Virgen del Rocío, Sevilla, Spain. [Dopazo,J]4Clinical Bioinformatics Area. Fundación Progreso y Salud (FPS). CDCA, Hospital Virgen del Rocio, Sevilla, Spain., This work is supported by grants SAF2017-88908-R from the Spanish Ministry of Economy and Competitiveness, PT17/0009/0006, ACCI2018/29 from CIBER-ISCIII and COV20/00788 from the ISCIII, co-funded with European Regional Development Funds (ERDF), the grant 'Large-scale drug repurposing in rare diseases by genomic Big Data analysis with machine learning methods' from the Fundación BBVA (G999088Q), as well as H2020 Programme of the European Union grants Marie Curie Innovative Training Network 'Machine Learning Frontiers in Precision Medicine' (MLFPM) (GA 813533)., Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), Instituto de Salud Carlos III, European Commission, Fundación BBVA
المصدر: Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy, Vol 5, Iss 1, Pp 1-3 (2020)
Digital.CSIC. Repositorio Institucional del CSIC
instnameمصطلحات موضوعية: Information Science::Information Science::Computing Methodologies::Computer Simulation::Molecular Docking Simulation [Medical Subject Headings], Cancer Research, Letter, Coronavirus disease 2019 (COVID-19), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Química computacional, Big data, Predictive medicine, lcsh:Medicine, Reposicionamiento de medicamentos, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Drug Therapy::Molecular Targeted Therapy [Medical Subject Headings], Machine learning, computer.software_genre, Marie curie, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], Machine Learning, Computational Chemistry, Simulación del acoplamiento molecular, Target identification, Genetics, media_common.cataloged_instance, Humans, Molecular Targeted Therapy, European union, lcsh:QH301-705.5, media_common, business.industry, SARS-CoV-2, lcsh:R, Drug Repositioning, Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Signal Transduction [Medical Subject Headings], COVID-19, Proteins, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins [Medical Subject Headings], Precision medicine, Terapia molecular dirigida, Aprendizaje automático, Diseases::Virus Diseases::RNA Virus Infections::Nidovirales Infections::Coronaviridae Infections::Coronavirus Infections [Medical Subject Headings], COVID-19 Drug Treatment, Molecular Docking Simulation, Drug repositioning, lcsh:Biology (General), Infectious diseases, Christian ministry, Artificial intelligence, business, computer, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Drug Discovery::Drug Repositioning [Medical Subject Headings], Signal Transduction
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ad6c62253a3ade149f0cc873a8bf936
https://www.nature.com/articles/s41392-020-00417-y.pdf -
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المؤلفون: Ávalos-Moreno, Marta, López-Tejada, Araceli, Blaya-Cánovas, Jose L., Cara-Lupiañez, Francisca E., González-González, Adrián, Lorente, Jose A., Sánchez-Rovira, Pedro, Granados-Principal, Sergio
المساهمون: [Ávalos-Moreno,M, López-Tejada,A, Blaya-Cánovas,JL, Cara-Lupiañez,FE, González-González,A, Lorente,JA, Granados-Principal,S] GENYO, Centre for Genomics and Oncological Research, Pfizer/University of Granada/Andalusian Regional Government, PTS Granada, Granada, Spain. [López-Tejada,A, Sánchez-Rovira,P, Granados-Principal,S] UGC de Oncología Médica, Complejo Hospitalario de Jaén, Jaén, Spain. [Lorente,JA] Department of Legal Medicine, School of Medicine—PTS—University of Granada, Granada, Spain., This work and S.G.P. was funded by Instituto de Salud Carlos III (CP19/00029, CP14/00197, PI19/01533, PI15/00336), Ministerio de Economía y Competitividad (RTC-2016-5674-1) and European Regional Development Fund (European Union). A.L.T. is funded by the Ministerio de Ciencia, Innovación y Universidades (FPU19/04450) and J.B.C. is supported by Fundación Científica Asociación Española Contra el Cáncer, Junta Provincial de Jaén (AECC) (PRDJA19001BLAY).
مصطلحات موضوعية: Células madre neoplásicas, Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Recurrence [Medical Subject Headings], Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Drug Discovery [Medical Subject Headings], Information Science::Information Science::Medical Informatics::Medical Informatics Applications::Information Storage and Retrieval::Data Mining [Medical Subject Headings], Cancer stem cells, Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biology::Computational Biology::Systems Biology [Medical Subject Headings], Drug repurposing, Ensayos clínicos como asunto, Chemicals and Drugs::Pharmaceutical Preparations::Drugs, Investigational [Medical Subject Headings], Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Signal Transduction [Medical Subject Headings], Reposicionamiento de medicamentos, Anatomy::Cells::Stem Cells::Neoplastic Stem Cells [Medical Subject Headings], Neoplasias de la mama triple negativas, Personalized medicine, Diseases::Neoplasms::Neoplasms by Site::Breast Neoplasms::Triple Negative Breast Neoplasms [Medical Subject Headings], Clinical trials, Triple-negative breast cancer, Computational methods, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Clinical Trials as Topic [Medical Subject Headings], Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Drug Discovery::Drug Repositioning [Medical Subject Headings], Medicina de precisión
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______2636::948a7fd4f28c3b834ab780db27964377
https://hdl.handle.net/10668/3692 -
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المؤلفون: Muñoz, Miguel, Coveñas, Rafael
المساهمون: [Muñoz,M] Research Laboratory on Neuropeptides (IBIS), Virgen del Rocío University Hospital, Sevilla, Spain. [Coveñas,R] Institute of Neurosciences of Castilla y León (INCYL), Laboratory of Neuroanatomy of the Peptidergic Systems, University of Salamanca, Salamanca, Spain., This research was funded by 'Programa XI: Financiación de Unidades de Excelencia de la Universidad de Salamanca' (Spain).
مصطلحات موضوعية: Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Neuropeptides::Tachykinins::Substance P [Medical Subject Headings], NK-1 receptor, Drug repositioning, Receptores de neuroquinina-1, Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Antineoplastic Agents [Medical Subject Headings], Emend, Apoptosis, Reposicionamiento de medicamentos, Antitumor, Substance P, Antineoplásicos, Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death::Apoptosis [Medical Subject Headings], Anti-angiogenesis, Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Genes, Neoplasm::Genes, Tumor Suppressor [Medical Subject Headings], Inhibidores de la angiogénesis, Sustancia P, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, Neurotransmitter::Receptors, Neuropeptide::Receptors, Tachykinin::Receptors, Neurokinin-1 [Medical Subject Headings], Genes Supresores de Tumor, Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Growth Substances::Growth Inhibitors::Angiogenesis Inhibitors [Medical Subject Headings], Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Drug Discovery::Drug Repositioning [Medical Subject Headings], Aprepitant, Antimetastasis
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______2636::2f9502dc8ce5c537d0abffcaf936543d
https://hdl.handle.net/10668/3686 -
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المؤلفون: Benavides-Cordoba, Vicente
المصدر: Colombia Médica, Volume: 51, Issue: 2, Article number: e4279, Published: 07 MAY 2020
مصطلحات موضوعية: medicamentos, Pandemia, Therapeutic alternatives, COVID-19, drug, Reposicionamiento de medicamentos, drug repositioning, pandemics, Alternativas terapéuticas
وصف الملف: text/html
URL الوصول: https://explore.openaire.eu/search/publication?articleId=od_______618::9290a9aea43ac8aaddc41da7f3c50c72
http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S1657-95342020000200002&lng=en&tlng=en -
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المؤلفون: Younes Smani, Rafael Ayerbe-Algaba, Raquel del Toro, Andrea Miró-Canturri, Manuel Mejías, Jerónimo Pachón
المساهمون: Universidad de Sevilla. Departamento de Medicina, Universidad de Sevilla. Departamento de Fisiología Médica y Biofísica, Instituto de Biomedicina de Sevilla (IBIS), [Miró-Canturri,A, Ayerbe-Algaba,R, Mejías,ME, Smani,Y] Clinical Unit of Infectious Diseases, Microbiology and Preventive Medicine, University Hospital Virgen del Rocío, Seville, Spain. [Miró-Canturri,A, Del Toro,R, Pachón,J, Smani,Y] Institute of Biomedicine of Seville (IBiS), University Hospital Virgen del Rocío, CSIC, University of Seville, Seville, Spain. [Del Toro,R] Department of Medical Physiology and Biophysics, Institute of Biomedicine of Seville, University of Seville, Seville, Spain. [Pachón,J] Department of Medicine, University of Seville, Seville, Spain., This study was supported by the Instituto de Salud Carlos III, Proyectos de Investigación en Salud (grants CP15/00132, PI16/01378 and PI19/01453) and by Plan Nacional de I+D+i 2013–2016 and Instituto de Salud Carlos III, Subdirección General de Redes y Centros de Investigación Coopera tiva, Ministerio de Ciencia, Innovación y Universidades, Spanish Network for Research in Infectious Diseases (REIPI RD16/0016/0009)—co-financed by European Development Regional Fund 'A way to achieve Europe', Operative program Intelligent Growth 2014–2020. Younes Smani is supported by the Subprograma Miguel Servet Tipo I from the Ministerio de Economía y Competitividad of Spain (CP15/00132)., Instituto de Salud Carlos III, Ministerio de Ciencia, Innovación y Universidades (España), Red Española de Investigación en Patología Infecciosa, European Commission, Ministerio de Economía y Competitividad (España)
المصدر: idUS: Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
Pharmaceuticals
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Digital.CSIC. Repositorio Institucional del CSIC
Pharmaceuticals, Vol 14, Iss 507, p 507 (2021)
Volume 14
Issue 6
Pages: 507مصطلحات موضوعية: 0301 basic medicine, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Clinical Laboratory Techniques::Microbiological Techniques::Bacteriological Techniques::Bacterial Load [Medical Subject Headings], Antibiotics, Pharmaceutical Science, modelos animales, medicine.disease_cause, Drug Discovery, Organisms::Eukaryota::Animals [Medical Subject Headings], Tamoxifeno, bacteria, Infecciones, tamoxifen, biology, Organisms::Bacteria::Gram-Negative Bacteria::Gram-Negative Facultatively Anaerobic Rods::Enterobacteriaceae::Escherichia::Escherichia coli [Medical Subject Headings], Acinetobacter baumannii, medicine.anatomical_structure, Medicine, Molecular Medicine, Bacterias, Infection, Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents::Anti-Bacterial Agents [Medical Subject Headings], medicine.drug, repurposing drug, medicine.drug_class, 030106 microbiology, Reposicionamiento de medicamentos, Article, Microbiology, Sepsis, Organisms::Bacteria::Gram-Negative Bacteria::Gram-Negative Aerobic Bacteria::Gram-Negative Aerobic Rods and Cocci::Moraxellaceae::Acinetobacter::Acinetobacter baumannii [Medical Subject Headings], 03 medical and health sciences, Pharmacy and materia medica, Immune system, medicine, Animal model, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice [Medical Subject Headings], Bacteria, Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Phosphotransferases::Phosphotransferases (Alcohol Group Acceptor)::Protein Kinases::Protein-Serine-Threonine Kinases::Mitogen-Activated Protein Kinases::Extracellular Signal-Regulated MAP Kinases::Mitogen-Activated Protein Kinase 3 [Medical Subject Headings], Pseudomonas aeruginosa, business.industry, animal model, Monocyte, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Intercellular Signaling Peptides and Proteins::Cytokines::Interleukins::Interleukin-18 [Medical Subject Headings], Organisms::Bacteria::Gram-Negative Bacteria::Gram-Negative Aerobic Bacteria::Gram-Negative Aerobic Rods and Cocci::Pseudomonadaceae::Pseudomonas::Pseudomonas aeruginosa [Medical Subject Headings], Repurposing drug, Anatomy::Hemic and Immune Systems::Immune System::Bone Marrow [Medical Subject Headings], biology.organism_classification, medicine.disease, Anatomy::Hemic and Immune Systems::Immune System::Phagocytes::Neutrophils [Medical Subject Headings], infection, RS1-441, Multiple drug resistance, immune system, Tamoxifen, 030104 developmental biology, Sistema inmunológico, business
وصف الملف: application/pdf
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المؤلفون: Sandro G. Viveiros Rosa, Wilson C. Santos
المصدر: Revista Panamericana de Salud Pública, Vol 44, Iss 40, Pp 1-7 (2020)
Revista Panamericana de Salud Públicaمصطلحات موضوعية: Oseltamivir, medicine.medical_specialty, lcsh:Arctic medicine. Tropical medicine, lcsh:RC955-962, infecciones por coronavirus, pneumonia, viral, lcsh:Medicine, Reposicionamiento de medicamentos, pandemias, drug repositioning, pandemics, Favipiravir, Brief Communication, medicine.disease_cause, ensaios clínicos como assunto, ensayos clínicos como asunto, viroses, coronavirus infection, 03 medical and health sciences, chemistry.chemical_compound, virus diseases, Pandemic, pneumonia viral, medicine, virosis, Intensive care medicine, Coronavirus, 030505 public health, clinical trials as topic, business.industry, lcsh:Public aspects of medicine, lcsh:R, Public Health, Environmental and Occupational Health, lcsh:RA1-1270, Lopinavir, neumonía viral, Clinical trial, Drug repositioning, chemistry, Reposicionamento de medicamentos, Ritonavir, 0305 other medical science, business, infecções por coronavirus, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf28f3aa8a36ce492ea2178140fc8a28
https://doi.org/10.26633/rpsp.2020.40
