المؤلفون: Wang JS; School of Pharmaceutical Sciences, Institute of Drug Discovery and Development, Zhengzhou University, Zhengzhou 450001, China; Engineering Center of Catalysis and Synthesis for Chiral Molecules, Department of Chemistry, Fudan University, Shanghai 200433, China; Shanghai Engineering Center of Industrial Asymmetric Catalysis for Chiral Drugs, Shanghai 200433, China., Zhao KX; School of Pharmaceutical Sciences, Institute of Drug Discovery and Development, Zhengzhou University, Zhengzhou 450001, China; Engineering Center of Catalysis and Synthesis for Chiral Molecules, Department of Chemistry, Fudan University, Shanghai 200433, China; Shanghai Engineering Center of Industrial Asymmetric Catalysis for Chiral Drugs, Shanghai 200433, China., Zhang K; School of Pharmaceutical Sciences, Institute of Drug Discovery and Development, Zhengzhou University, Zhengzhou 450001, China; Engineering Center of Catalysis and Synthesis for Chiral Molecules, Department of Chemistry, Fudan University, Shanghai 200433, China; Shanghai Engineering Center of Industrial Asymmetric Catalysis for Chiral Drugs, Shanghai 200433, China., Pannecouque C; Rega Institute for Medical Research, KU Leuven, Herestraat 49 B-3000, Leuven, Belgium., De Clercq E; Rega Institute for Medical Research, KU Leuven, Herestraat 49 B-3000, Leuven, Belgium., Wang S; Engineering Center of Catalysis and Synthesis for Chiral Molecules, Department of Chemistry, Fudan University, Shanghai 200433, China; Shanghai Engineering Center of Industrial Asymmetric Catalysis for Chiral Drugs, Shanghai 200433, China. Electronic address: shuaiwang@fudan.edu.cn., Chen FE; School of Pharmaceutical Sciences, Institute of Drug Discovery and Development, Zhengzhou University, Zhengzhou 450001, China; Engineering Center of Catalysis and Synthesis for Chiral Molecules, Department of Chemistry, Fudan University, Shanghai 200433, China; Shanghai Engineering Center of Industrial Asymmetric Catalysis for Chiral Drugs, Shanghai 200433, China. Electronic address: rfchen@fudan.edu.cn.

المصدر: Bioorganic chemistry [Bioorg Chem] 2024 Jun; Vol. 147, pp. 107340. Date of Electronic Publication: 2024 Apr 05.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

مواضيع طبية MeSH: Anti-HIV Agents*/pharmacology , Anti-HIV Agents*/chemistry , Anti-HIV Agents*/chemical synthesis , Biphenyl Compounds*/antagonists & inhibitors , Biphenyl Compounds*/pharmacology , Biphenyl Compounds*/chemistry , Drug Design* , HIV Reverse Transcriptase*/antagonists & inhibitors , HIV Reverse Transcriptase*/metabolism , HIV-1*/drug effects , HIV-1*/enzymology , Quinazolines*/pharmacology , Quinazolines*/chemistry , Quinazolines*/chemical synthesis , Reverse Transcriptase Inhibitors*/pharmacology , Reverse Transcriptase Inhibitors*/chemistry , Reverse Transcriptase Inhibitors*/chemical synthesis , Solubility*, Humans ; Dose-Response Relationship, Drug ; Drug Resistance, Viral/drug effects ; Microbial Sensitivity Tests ; Molecular Docking Simulation ; Molecular Structure ; Structure-Activity Relationship

المؤلفون: Zhang Y; Department of Chemistry, University of Shanghai for Science and Technology, Shanghai, P. R. China., Chen L; Department of Chemistry, University of Shanghai for Science and Technology, Shanghai, P. R. China., Wang Z; School of Chemical and Environmental Engineering, Shanghai Institute of Technology, Shanghai, P. R. China., Zhu Y; Department of Chemistry, University of Shanghai for Science and Technology, Shanghai, P. R. China., Jiang H; Department of Chemistry, University of Shanghai for Science and Technology, Shanghai, P. R. China., Xu J; Department of Chemistry, University of Shanghai for Science and Technology, Shanghai, P. R. China., Xiong F; Department of Chemistry, University of Shanghai for Science and Technology, Shanghai, P. R. China.

المصدر: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2024 May; Vol. 42 (8), pp. 4196-4213. Date of Electronic Publication: 2023 Jun 05.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: England NLM ID: 8404176 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-0254 (Electronic) Linking ISSN: 07391102 NLM ISO Abbreviation: J Biomol Struct Dyn Subsets: MEDLINE

مواضيع طبية MeSH: Molecular Docking Simulation* , Molecular Dynamics Simulation* , Quantitative Structure-Activity Relationship* , Drug Design* , HIV Reverse Transcriptase*/antagonists & inhibitors , HIV Reverse Transcriptase*/chemistry , HIV Reverse Transcriptase*/metabolism , Reverse Transcriptase Inhibitors*/chemistry , Reverse Transcriptase Inhibitors*/pharmacology , Hydrogen Bonding*, HIV-1/drug effects ; Protein Binding ; Humans ; Ligands ; Anti-HIV Agents/chemistry ; Anti-HIV Agents/pharmacology ; Anti-HIV Agents/metabolism ; Binding Sites

المؤلفون: Thammajong P; Department of Biomedical Engineering, School of Engineering, King Mongkut's Institute of Technology Ladkrabang, Bangkok, Thailand., Aiebchun T; Department of Biochemistry, Faculty of Science, Kasetsart University, Bangkok, Thailand., Boonyarattanakalin K; College of Materials Innovation and Technology, King Mongkut's Institute of Technology Ladkrabang, Bangkok, Thailand., Gleeson D; Department of Chemistry & Applied Computational Chemistry Research Unit, School of Science, King Mongkut's Institute of Technology Ladkrabang, Bangkok, Thailand., Pobsuk N; Department of Chemistry, Faculty of Science, Kasetsart University, Bangkok, Thailand., Hannongbua S; Department of Chemistry, Faculty of Science, Kasetsart University, Bangkok, Thailand., Choowongkomon K; Department of Biochemistry, Faculty of Science, Kasetsart University, Bangkok, Thailand., Gleeson MP; Department of Biomedical Engineering, School of Engineering, King Mongkut's Institute of Technology Ladkrabang, Bangkok, Thailand.

المصدر: Chemical biology & drug design [Chem Biol Drug Des] 2024 May; Vol. 103 (5), pp. e14530.

نوع المنشور: Journal Article; Comparative Study; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101262549 Publication Model: Print Cited Medium: Internet ISSN: 1747-0285 (Electronic) Linking ISSN: 17470277 NLM ISO Abbreviation: Chem Biol Drug Des Subsets: MEDLINE

مواضيع طبية MeSH: Reverse Transcriptase Inhibitors*/pharmacology , Reverse Transcriptase Inhibitors*/chemistry , Immunodeficiency Virus, Feline*/drug effects , HIV Reverse Transcriptase*/antagonists & inhibitors , HIV Reverse Transcriptase*/metabolism, Animals ; Cats ; Humans ; Structure-Activity Relationship ; Pyrimidines/chemistry ; Pyrimidines/pharmacology ; Alkynes/chemistry ; Alkynes/pharmacology ; HIV-1/drug effects ; HIV-1/enzymology ; Cyclopropanes/pharmacology ; Cyclopropanes/chemistry ; Molecular Docking Simulation ; Benzoxazines/chemistry ; Benzoxazines/pharmacology

المؤلفون: Wahl D; Department of Health and Exercise Science, Colorado State University, Fort Collins, CO, United States of America; Columbine Health Systems Center for Healthy Aging, Colorado State University, Fort Collins, CO, United States of America., Grant RA; Department of Health and Exercise Science, Colorado State University, Fort Collins, CO, United States of America; Columbine Health Systems Center for Healthy Aging, Colorado State University, Fort Collins, CO, United States of America., LaRocca TJ; Department of Health and Exercise Science, Colorado State University, Fort Collins, CO, United States of America; Columbine Health Systems Center for Healthy Aging, Colorado State University, Fort Collins, CO, United States of America. Electronic address: Tom.LaRocca@Colostate.edu.

المصدر: Experimental gerontology [Exp Gerontol] 2024 Jul; Vol. 192, pp. 112458. Date of Electronic Publication: 2024 May 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 0047061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6815 (Electronic) Linking ISSN: 05315565 NLM ISO Abbreviation: Exp Gerontol Subsets: MEDLINE

مواضيع طبية MeSH: Hippocampus*/metabolism , Hippocampus*/drug effects , Tauopathies*/drug therapy , Tauopathies*/genetics , Transcriptome* , Disease Models, Animal* , Reverse Transcriptase Inhibitors*/pharmacology , Lamivudine*/pharmacology , Lamivudine*/therapeutic use, Animals ; Mice ; Male ; Female ; Neuroinflammatory Diseases/drug therapy ; Neuroinflammatory Diseases/genetics ; Mice, Transgenic ; Inflammation/drug therapy

المؤلفون: Lootens O; Centre of Excellence in Mycotoxicology and Public Health, Department of Bioanalysis, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium.; Laboratory of Medical Biochemistry and Clinical Analysis, Department of Bioanalysis, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium.; MYTOX-SOUTH®, International Thematic Network, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium., De Boevre M; Centre of Excellence in Mycotoxicology and Public Health, Department of Bioanalysis, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium.; MYTOX-SOUTH®, International Thematic Network, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium., Gasthuys E; Laboratory of Medical Biochemistry and Clinical Analysis, Department of Bioanalysis, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium., De Saeger S; Centre of Excellence in Mycotoxicology and Public Health, Department of Bioanalysis, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium.; MYTOX-SOUTH®, International Thematic Network, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium.; Department of Biotechnology and Food Technology, Faculty of Science, University of Johannesburg, Doornfontein Campus, P.O. Box 17011, Gauteng 2028, South Africa., Van Bocxlaer J; Laboratory of Medical Biochemistry and Clinical Analysis, Department of Bioanalysis, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium., Vermeulen A; Laboratory of Medical Biochemistry and Clinical Analysis, Department of Bioanalysis, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium.

المصدر: Toxins [Toxins (Basel)] 2024 Jun 04; Vol. 16 (6). Date of Electronic Publication: 2024 Jun 04.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101530765 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6651 (Electronic) Linking ISSN: 20726651 NLM ISO Abbreviation: Toxins (Basel) Subsets: MEDLINE

مواضيع طبية MeSH: Aflatoxin B1*/pharmacokinetics , Aflatoxin B1*/toxicity , Benzoxazines*/pharmacokinetics , Benzoxazines*/metabolism , Alkynes* , Cyclopropanes* , Microsomes, Liver*/metabolism , Microsomes, Liver*/drug effects , Drug Interactions* , Models, Biological* , Reverse Transcriptase Inhibitors*/pharmacokinetics, Humans ; Male ; Cytochrome P-450 CYP3A/metabolism ; Adult ; Female ; Cytochrome P-450 CYP1A2/metabolism ; Middle Aged ; Young Adult ; White People

المؤلفون: Costa-Tuna A; CQC-IMS, Department of Chemistry, University of Coimbra, Rua Larga, 3004-535 Coimbra, Portugal., Chaves OA; CQC-IMS, Department of Chemistry, University of Coimbra, Rua Larga, 3004-535 Coimbra, Portugal.; Laboratory of Immunopharmacology, Centro de Pesquisa, Inovação e Vigilância em COVID-19 e Emergências Sanitárias (CPIV), Oswaldo Cruz Institute (IOC), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro 21040-361, RJ, Brazil., Almeida ZL; CQC-IMS, Department of Chemistry, University of Coimbra, Rua Larga, 3004-535 Coimbra, Portugal., Cunha RS; CQC-IMS, Department of Chemistry, University of Coimbra, Rua Larga, 3004-535 Coimbra, Portugal., Pina J; CQC-IMS, Department of Chemistry, University of Coimbra, Rua Larga, 3004-535 Coimbra, Portugal., Serpa C; CQC-IMS, Department of Chemistry, University of Coimbra, Rua Larga, 3004-535 Coimbra, Portugal.

المصدر: Viruses [Viruses] 2024 Mar 22; Vol. 16 (4). Date of Electronic Publication: 2024 Mar 22.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE

مواضيع طبية MeSH: Tenofovir*/*analogs & derivatives, Reverse Transcriptase Inhibitors*/metabolism , Reverse Transcriptase Inhibitors*/chemistry , Tenofovir*/metabolism , Tenofovir*/chemistry , Serum Albumin, Human*/metabolism , Serum Albumin, Human*/chemistry , Protein Binding* , Anti-HIV Agents*/metabolism, Humans ; Thermodynamics ; Calorimetry ; Binding Sites ; HIV Infections/virology ; HIV Infections/drug therapy ; Alanine/metabolism ; HIV Reverse Transcriptase/metabolism ; HIV Reverse Transcriptase/chemistry

المؤلفون: Sun Y; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Culture Road ,Jinan ,Shandong 250012, P.R. China., Zhou Z; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Culture Road ,Jinan ,Shandong 250012, P.R. China., Wang N; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Culture Road ,Jinan ,Shandong 250012, P.R. China., Zhao F; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Culture Road ,Jinan ,Shandong 250012, P.R. China., Liu Y; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Culture Road ,Jinan ,Shandong 250012, P.R. China., Xu X; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Culture Road ,Jinan ,Shandong 250012, P.R. China., Wang X; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Culture Road ,Jinan ,Shandong 250012, P.R. China., Gou Z; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Culture Road ,Jinan ,Shandong 250012, P.R. China., De Clercq E; Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, K.U. Leuven, Herestraat 49 Postbus 1043 (09.A097), Leuven B-3000, Belgium., Pannecouque C; Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, K.U. Leuven, Herestraat 49 Postbus 1043 (09.A097), Leuven B-3000, Belgium., Zhan P; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Culture Road ,Jinan ,Shandong 250012, P.R. China.; China-Belgium Collaborative Research Center for Innovative Antiviral Drugs of Shandong Province, Jinan 250012, P.R. China., Kang D; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Culture Road ,Jinan ,Shandong 250012, P.R. China.; China-Belgium Collaborative Research Center for Innovative Antiviral Drugs of Shandong Province, Jinan 250012, P.R. China., Liu X; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Culture Road ,Jinan ,Shandong 250012, P.R. China.; China-Belgium Collaborative Research Center for Innovative Antiviral Drugs of Shandong Province, Jinan 250012, P.R. China.

المصدر: Journal of medicinal chemistry [J Med Chem] 2024 Apr 25; Vol. 67 (8), pp. 6570-6584. Date of Electronic Publication: 2024 Apr 13.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: HIV-1*/drug effects , Triazoles*/chemistry , Triazoles*/pharmacology , Triazoles*/pharmacokinetics , Anti-HIV Agents*/pharmacology , Anti-HIV Agents*/chemistry , Anti-HIV Agents*/chemical synthesis , Anti-HIV Agents*/pharmacokinetics , Reverse Transcriptase Inhibitors*/pharmacology , Reverse Transcriptase Inhibitors*/chemistry , Reverse Transcriptase Inhibitors*/chemical synthesis , Reverse Transcriptase Inhibitors*/pharmacokinetics , Molecular Docking Simulation* , Dihydropyridines*/chemistry , Dihydropyridines*/pharmacology , Dihydropyridines*/pharmacokinetics, Humans ; Structure-Activity Relationship ; HIV Reverse Transcriptase/antagonists & inhibitors ; HIV Reverse Transcriptase/metabolism ; Animals ; Male ; Drug Discovery ; Molecular Structure ; Mice

المؤلفون: Vos WAJW; Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.; Department of Internal Medicine and Infectious Diseases, OLVG, 1091 AC Amsterdam, The Netherlands., Vadaq N; Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands., Matzaraki V; Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands., Otten T; Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands., Groenendijk AL; Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.; Department of Medical Microbiology and Infectious Diseases, ErasmusMC, Erasmus University, 3015 CN Rotterdam, The Netherlands., Blaauw MJT; Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.; Department of Internal Medicine and Infectious Diseases, Elizabeth-Tweesteden Ziekenhuis, 5022 GC Tilburg, The Netherlands., van Eekeren LE; Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands., Brinkman K; Department of Internal Medicine and Infectious Diseases, OLVG, 1091 AC Amsterdam, The Netherlands., de Mast Q; Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands., Riksen NP; Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands., Stalenhoef AFH; Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands., van Lunzen J; Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands., van der Ven AJAM; Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands., Blok WL; Department of Internal Medicine and Infectious Diseases, OLVG, 1091 AC Amsterdam, The Netherlands., Stalenhoef JE; Department of Internal Medicine and Infectious Diseases, OLVG, 1091 AC Amsterdam, The Netherlands.

المصدر: Viruses [Viruses] 2024 Apr 10; Vol. 16 (4). Date of Electronic Publication: 2024 Apr 10.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Comparative Study

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE

مواضيع طبية MeSH: HIV Infections*/drug therapy , Reverse Transcriptase Inhibitors*/therapeutic use , HIV Integrase Inhibitors*/therapeutic use, Humans ; Male ; Female ; Middle Aged ; Adult ; Metabolome/drug effects ; Anti-HIV Agents/therapeutic use ; Metabolomics ; Cohort Studies ; Antiretroviral Therapy, Highly Active

المؤلفون: Thoueille P; Service and Laboratory of Clinical Pharmacology, Department of Laboratory Medicine and Pathology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Delarive L; Service and Laboratory of Clinical Pharmacology, Department of Laboratory Medicine and Pathology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Cavassini M; Service of Infectious Diseases, Department of Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Buclin T; Service and Laboratory of Clinical Pharmacology, Department of Laboratory Medicine and Pathology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Decosterd LA; Service and Laboratory of Clinical Pharmacology, Department of Laboratory Medicine and Pathology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Marzolini C; Service and Laboratory of Clinical Pharmacology, Department of Laboratory Medicine and Pathology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, University of Basel, Basel, Switzerland.; Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK., Girardin FR; Service and Laboratory of Clinical Pharmacology, Department of Laboratory Medicine and Pathology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Guidi M; Service and Laboratory of Clinical Pharmacology, Department of Laboratory Medicine and Pathology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; Center for Research and Innovation in Clinical Pharmaceutical Sciences, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, University of Lausanne, Geneva, Switzerland.

مؤلفون مشاركون: Swiss HIV Cohort Study

المصدر: British journal of clinical pharmacology [Br J Clin Pharmacol] 2024 Apr; Vol. 90 (4), pp. 1058-1065. Date of Electronic Publication: 2024 Jan 16.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2125 (Electronic) Linking ISSN: 03065251 NLM ISO Abbreviation: Br J Clin Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Reverse Transcriptase Inhibitors*/pharmacokinetics , HIV Infections*/drug therapy , Triazoles*, Humans ; Aged, 80 and over ; Middle Aged ; Cytochrome P-450 CYP3A Inhibitors/therapeutic use ; Pyridones/pharmacokinetics

المؤلفون: Brochard T; Laboratory Genetic Metabolic Diseases, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands., McIntyre RL; Laboratory Genetic Metabolic Diseases, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands; Amsterdam Gastroenterology, Endocrinology and Metabolism Institute, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands., Houtkooper RH; Laboratory Genetic Metabolic Diseases, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands; Amsterdam Gastroenterology, Endocrinology and Metabolism Institute, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands; Amsterdam Cardiovascular Sciences, Amsterdam, the Netherlands., Seluanov A; Departments of Biology and Medicine, University of Rochester, Rochester, NY, USA., Gorbunova V; Departments of Biology and Medicine, University of Rochester, Rochester, NY, USA., Janssens GE; Laboratory Genetic Metabolic Diseases, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands; Amsterdam Gastroenterology, Endocrinology and Metabolism Institute, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: g.e.janssens@amsterdamumc.nl.

المصدر: Ageing research reviews [Ageing Res Rev] 2023 Dec; Vol. 92, pp. 102132. Date of Electronic Publication: 2023 Nov 19.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 101128963 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9649 (Electronic) Linking ISSN: 15681637 NLM ISO Abbreviation: Ageing Res Rev Subsets: MEDLINE

مواضيع طبية MeSH: Reverse Transcriptase Inhibitors*/adverse effects , HIV Infections*/drug therapy, Humans ; Nucleosides/pharmacology ; Nucleosides/therapeutic use ; Drug Repositioning ; Aging