-
1
المؤلفون: Andrew T. Watt, Michael E. Østergaard, Pawan Kumar, Pawan K. Sharma, Punit P. Seth, Josh G. Nichols, Poul Nielsen
المصدر: Østergaard, M E, Kumar, P, Nichols, J, Watt, A, Sharma, P K, Nielsen, P & Seth, P P 2015, ' Allele-Selective Inhibition of Mutant Huntingtin with 2-Thio-and C5-Triazolylphenyl-Deoxythymidine-Modified Antisense Oligonucleotides ', Nucleic Acid Therapeutics, vol. 25, no. 5, pp. 266-274 . https://doi.org/10.1089/nat.2015.0547
مصطلحات موضوعية: Thymidine/analogs & derivatives, Oligonucleotides, Antisense/genetics, Huntingtin, RNase P, Mutant, Ribonuclease H, Nerve Tissue Proteins, Biology, Biochemistry, Drug Discovery, Genetics, Huntingtin Protein, Nerve Tissue Proteins/genetics, Humans, RNase H, Molecular Biology, Base Pairing, Alleles, RNA Cleavage, Messenger RNA, DNA Repeat Expansion, Ribonuclease H/physiology, Base Sequence, Oligonucleotide, RNA, Oligonucleotides, Antisense, Molecular biology, biology.protein, Molecular Medicine, Mutant Proteins, Mutant Proteins/genetics, Thymidine