يعرض 1 - 10 نتائج من 114 نتيجة بحث عن '"Richard M. Elledge"', وقت الاستعلام: 1.03s تنقيح النتائج
  1. 1
    Abstract PS5-31: Molecular markers of response to s-equol, a novel oral estrogen receptor (ER) beta agonist for triple negative breast cancer

    المؤلفون: Richard M. Elledge, Courtney Thomas, Jonathan Gelfond, Sarah Hackman, Kate Lathrop, Virginia G. Kaklamani, Alia Nazarullah, Andrew Brenner, Rong Li, Marisa Rodriguez

    المصدر: Cancer Research. 81:PS5-31

    مصطلحات موضوعية: Oncology, Agonist, Cancer Research, medicine.medical_specialty, Tumor-infiltrating lymphocytes, medicine.drug_class, business.industry, Cancer, Estrogen receptor, medicine.disease, Breast cancer, Estrogen, Internal medicine, medicine, business, Triple-negative breast cancer, Estrogen receptor beta

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f23a21a61e4067489176b9826398940a
    https://doi.org/10.1158/1538-7445.sabcs20-ps5-31

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  2. 2
    ERα-related chromothripsis enhances concordant gene transcription on chromosome 17q11.1-q24.1 in luminal breast cancer

    المؤلفون: Nameer B. Kirma, Tim H M Huang, Virginia G. Kaklamani, Chia-Nung Hung, Kate Lathrop, Chih-Wei Chou, Ya-Ting Hsu, Chun Liang Chen, Meizhen Chen, Chun-Lin Lin, Kohzoh Mitsuya, Richard M. Elledge, Ching-Hung Lin, Meena Kusi, Chiou-Miin Wang, Xi Tan

    المصدر: BMC Medical Genomics
    BMC Medical Genomics, Vol 13, Iss 1, Pp 1-18 (2020)

    مصطلحات موضوعية: Druggable target, Genome instability, lcsh:Internal medicine, lcsh:QH426-470, Transcription, Genetic, Nanopore sequencing, Breast Neoplasms, Chromosomal rearrangement, Biology, Exome Sequencing, Biomarkers, Tumor, Tumor Cells, Cultured, Genetics, Humans, lcsh:RC31-1245, Genetics (clinical), Cell Proliferation, ERα, Whole genome sequencing, Chromothripsis, Whole Genome Sequencing, Cell Cycle, Estrogen Receptor alpha, Chromosome, Prognosis, Chromatin, Gene Expression Regulation, Neoplastic, Survival Rate, Luminal subtype breast cancer, Chromosome 17 (human), lcsh:Genetics, Tumor progression, Cancer research, Female, Concordant transcription, Chromosomes, Human, Pair 17, Research Article

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::512e0e01a5288fdc02e4453064d7f653
    https://doi.org/10.1186/s12920-020-0729-7

    Find this article in full text from Springer Verlag. Find this article in full text from ProQuest
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  3. 3
    Abstract PD5-08: Not presented

    المؤلفون: Richard M. Elledge, Donald A. Richards, Sharon Wilks, Peter Kabos, Virginia G. Kaklamani, H Jiang, D Wang, Aditya Bardia, A O'Neill, Wael A. Harb, F Garner

    المصدر: Cancer Research. 78:PD5-08

    مصطلحات موضوعية: Cancer Research, Oncology

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c266fb50e1f45f7e23d4748071cf9702
    https://doi.org/10.1158/1538-7445.sabcs17-pd5-08

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  4. 4
    Tyrosine phosphorylation regulates ERβ ubiquitination, protein turnover, and inhibition of breast cancer

    المؤلفون: Long Cheng, Ratna K. Vadlamudi, Harshita Gupta, Degeng Wang, Kshama Gupta, Kate Lathrop, Huai-Chin Chiang, Rong Li, Stanton F. McHardy, Bin Yuan, Gangadhara R. Sareddy, Richard M Elledge, Yanfen Hu, Tyler J. Curiel, Qinong Ye, Pei Wang

    المصدر: Oncotarget

    مصطلحات موضوعية: 0301 basic medicine, Proteasome Endopeptidase Complex, Cell Survival, Estrogen receptor, Mice, Nude, Antineoplastic Agents, Breast Neoplasms, P300-CBP Transcription Factors, ubiquitination, Ligands, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Medicine, ERβ, Animals, Estrogen Receptor beta, Humans, antitumor activity, p300-CBP Transcription Factors, Tyrosine, Phosphorylation, Phosphotyrosine, Estrogen receptor beta, Cell Proliferation, Cell growth, business.industry, protein turnover, HEK 293 cells, tyrosine phosphorylation, Tyrosine phosphorylation, 3. Good health, Cell biology, 030104 developmental biology, HEK293 Cells, Ki-67 Antigen, Oncology, chemistry, 030220 oncology & carcinogenesis, MCF-7 Cells, Female, business, Neoplasm Transplantation, Research Paper

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5a289769e5b72891ed2c02ae6752061
    http://europepmc.org/articles/PMC5173158

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  5. 5
    Endocrine Therapy for Leptomeningeal Metastases from ER ‐Positive Breast Cancer: Case Report and a Review of the Literature

    المؤلفون: Richard M Elledge, Behyar Zoghi

    المصدر: The Breast Journal. 22:218-223

    مصطلحات موضوعية: Oncology, medicine.medical_specialty, Antineoplastic Agents, Hormonal, Estrogen receptor, Breast Neoplasms, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, Internal medicine, Meningeal Neoplasms, Internal Medicine, Humans, Medicine, Endocrine system, business.industry, Incidence (epidemiology), Endocrine therapy, Middle Aged, medicine.disease, Surgery, Receptors, Estrogen, 030220 oncology & carcinogenesis, Hormonal therapy, Female, business, Complication, 030217 neurology & neurosurgery, Hormone

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::625316695e8a7aa310e969ebece813a7
    https://doi.org/10.1111/tbj.12554

    View record at Wiley
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  6. 6
    p53-Based strategy to reduce hematological toxicity of chemotherapy: A proof of principle study

    المؤلفون: Richard M Elledge, Zhi-Min Yuan, Ronan T. Swords, Tony Yuen Eng, Carol A. Jenkins, Richard L. Crownover, Joel E. Michalek, Anand B. Karnad, Chul S. Ha, Brad H. Pollock, Kevin R. Kelly, Suthakar Ganapathy, Gregory P. Swanson, Su Hang, Martin Goros, Athanassios Argiris

    المصدر: Molecular Oncology. 10:148-156

    مصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, medicine.medical_treatment, Antineoplastic Agents, Arsenic, 03 medical and health sciences, 0302 clinical medicine, Bone Marrow, Internal medicine, White blood cell, Genetics, medicine, Humans, Chemotherapy, Myelosuppressive Chemotherapy, Dose-Response Relationship, Drug, medicine.diagnostic_test, business.industry, Complete blood count, Articles, General Medicine, Surgery, Radiation therapy, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Toxicity, Absolute neutrophil count, Molecular Medicine, Bone marrow, Tumor Suppressor Protein p53, business

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b3008bd0ccd36f5bcd0834514fa98df
    https://doi.org/10.1016/j.molonc.2015.09.004

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  7. 7
    Novel estrogen receptor beta agonist S-equol decreases tumor proliferation in patients with triple negative breast cancer (TNBC)

    المؤلفون: Marisa Rodriguez, Kate Ida Lathrop, Virginia G. Kaklamani, Alia Nazarullah, Andrew Brenner, Jonathan Gelfond, Sarah Hackman, Courtney Thomas, Richard M. Elledge, Rong Li

    المصدر: Journal of Clinical Oncology. 38:560-560

    مصطلحات موضوعية: Agonist, Cancer Research, business.industry, medicine.drug_class, Treatment outcome, medicine.disease, Breast cancer, Oncology, Estrogen, Cancer research, Medicine, (S)-Equol, In patient, business, Triple-negative breast cancer, Estrogen receptor beta

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::db289ea0c4ecd1048dd59833d96cc7ad
    https://doi.org/10.1200/jco.2020.38.15_suppl.560

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  8. 8
    Intrinsic apoptotic pathway activation increases response to anti-estrogens in luminal breast cancers

    المؤلفون: Bushra Rahman, Meghan Morrison Joly, Courtney McKernan, Michelle M. Williams, Rebecca S. Cook, Violeta Sanchez, Monica V. Estrada, Linus Lee, Richard M. Elledge, David L. Elion, Donna J. Hicks, Thomas A. Werfel, Suleiman Massarweh, Craig L. Duvall

    المصدر: Cell Death & Disease
    Cell Death and Disease, Vol 9, Iss 2, Pp 1-14 (2018)

    مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Immunology, bcl-X Protein, Down-Regulation, Estrogen receptor, Apoptosis, Breast Neoplasms, Article, Mice, 03 medical and health sciences, Cellular and Molecular Neuroscience, Breast cancer, Downregulation and upregulation, Cell Line, Tumor, medicine, Animals, Humans, Endocrine system, lcsh:QH573-671, Aromatase, Receptor, Fulvestrant, Sulfonamides, Aniline Compounds, biology, lcsh:Cytology, business.industry, Estrogen Antagonists, Cell Biology, medicine.disease, Up-Regulation, 3. Good health, 030104 developmental biology, Receptors, Estrogen, Gene Targeting, biology.protein, Cancer research, Myeloid Cell Leukemia Sequence 1 Protein, Female, business, Signal Transduction, medicine.drug

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d609e79f500c9b89c48b79959fb6a32a
    https://doi.org/10.1038/s41419-017-0072-x

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  9. 9
    Effects of Radiation Therapy on Breast Epithelial Cells in BRCA1/2 Mutation Carriers

    المؤلفون: Rong Li, Ismail Jatoi, Paula Larson, Huai-Chin Chiang, Yanfen Hu, Richard M Elledge

    المصدر: Breast Cancer: Basic and Clinical Research, Vol 2015, Iss 9, Pp 25-29 (2015)
    Breast Cancer : Basic and Clinical Research

    مصطلحات موضوعية: Cancer Research, Microarray, endocrine system diseases, medicine.medical_treatment, Population, Bioinformatics, radiation therapy, lcsh:RC254-282, Flow cytometry, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, BRCA1/2, medicine, Progenitor cell, education, skin and connective tissue diseases, 030304 developmental biology, Original Research, 0303 health sciences, education.field_of_study, medicine.diagnostic_test, business.industry, Cancer, luminal epithelial cells, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, 3. Good health, Unilateral Breast Neoplasms, Radiation therapy, Oncology, 030220 oncology & carcinogenesis, Cancer research, business

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c03db7cacfa3d328b3f375681b75940
    http://www.la-press.com/effects-of-radiation-therapy-on-breast-epithelial-cells-in-brca12-muta-article-a4877

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  10. 10
    Attenuation of RNA polymerase II pausing mitigates BRCA1-associated R-loop accumulation and tumorigenesis

    المؤلفون: Frédéric Chédin, Constantine Theoharis, Beth N. Peshkin, Meeghan A. Lautner, Victor X. Jin, Boyce B Oliver, Anna Petit, Huai-Chin Chiang, Xiaowen Zhang, Tyler J. Curiel, Yao Wang, Elizabeth Poggi, Rong Li, Sreejith J. Nair, Miguel Angel Pujana, Claudine Isaacs, Joan Brunet, Krysta Chaldekas, Richard M Elledge, Ismail Jatoi, Yanfen Hu, Chi Zhang, Joel E. Michalek, Oscar Ochoa, Xiayan Zhao, Teresa Soler, Francesca Mateo, Howard T. Wang, Lu-Zhe Sun, Sabrina Smith

    المصدر: Nature communications, vol 8, iss 1
    Nature Communications
    Dipòsit Digital de la UB
    Universidad de Barcelona
    Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
    Recercat. Dipósit de la Recerca de Catalunya
    instname

    مصطلحات موضوعية: 0301 basic medicine, R-loop, Carcinogenesis, Cell, General Physics and Astronomy, RNA-binding protein, RNA polymerase II, medicine.disease_cause, Mice, Transcription (biology), 2.1 Biological and endogenous factors, Breast, Aetiology, Promoter Regions, Genetic, skin and connective tissue diseases, Cancer, Mice, Knockout, Multidisciplinary, BRCA1 Protein, RNA-Binding Proteins, Nuclear Proteins, medicine.anatomical_structure, Female, RNA Polymerase II, Science, Knockout, Breast Neoplasms, Biology, General Biochemistry, Genetics and Molecular Biology, Article, Càncer de mama, Promoter Regions, 03 medical and health sciences, Genetic, Breast Cancer, medicine, Genetics, Animals, Humans, Gene, Tumor Suppressor Proteins, DNA replication, Correction, General Chemistry, 030104 developmental biology, biology.protein, Cancer research, Nucleic Acid Conformation

    وصف الملف: application/pdf

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebfb2d661f14aef7e1fd7059dfd72dcd
    https://escholarship.org/uc/item/64t102b5

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