نتائج البحث - "Richard P. E. van Dokkum"

1

Vildagliptin Restores Renal Myogenic Function and Attenuates Renal Sclerosis Independently of Effects on Blood Glucose or Proteinuria in Zucker Diabetic Fatty Rat

المؤلفون: Yumei Wang, Richard P. E. van Dokkum, Sjoerd W. Landheer, Hendrik Buikema, Robert H. Henning, Peter Vavrinec, Leo E. Deelman

المساهمون: Groningen Kidney Center (GKC), Vascular Ageing Programme (VAP), Groningen Institute for Organ Transplantation (GIOT)

المصدر: Current Vascular Pharmacology, 12(6), 836-844. BENTHAM SCIENCE PUBL LTD

مصطلحات موضوعية: Blood Glucose, Male, Pyrrolidines, FAWN-HOODED RAT, endocrine system diseases, Adamantane, ISCHEMIA-REPERFUSION INJURY, Kidney, urologic and male genital diseases, ZDF rat, Random Allocation, Chronic kidney disease, myogenic constriction, oxidative stress, Diabetic Nephropathies, Vildagliptin, METABOLIC SYNDROME, GLUCAGON-LIKE PEPTIDE-1, Proteinuria, OBESITY, medicine.symptom, Cardiology and Cardiovascular Medicine, glomerulosclerosis, medicine.drug, medicine.medical_specialty, UNITED-STATES, type 2 diabetes melitus, Renal Circulation, Nephropathy, Diabetes mellitus, Internal medicine, Nitriles, medicine, Renal fibrosis, Animals, Pharmacology, Dipeptidyl-Peptidase IV Inhibitors, Sclerosis, RECEPTOR, business.industry, GENE-THERAPY, nutritional and metabolic diseases, Glomerulosclerosis, SIGNALING MECHANISMS, medicine.disease, Rats, Rats, Zucker, DPP-IV inhibitors, Endocrinology, Diabetes Mellitus, Type 2, Vasoconstriction, GLOMERULAR INJURY, Metabolic syndrome, business, Kidney disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::062c7716b6537f07ee37bbc0d557692e
https://doi.org/10.2174/15701611113116660151

2

Tacrolimus-induced hypertension and nephrotoxicity in Fawn-Hooded rats are attenuated by dual inhibition of renin–angiotensin system

المؤلفون: Luděk Červenka, Alžbeta Vojtíšková, Lenka Hošková, Josef Kautzner, Libor Kopkan, Eva Honsova, Šárka Varcabová, Zuzana Husková, Richard P. E. van Dokkum, Ivan Málek

المصدر: HYPERTENSION RESEARCH, 37(8), 724-732. Nature Publishing Group

مصطلحات موضوعية: Male, arterial hypertension, medicine.medical_specialty, REN-2 TRANSGENIC RATS, RENAL-FAILURE, KIDNEY-TRANSPLANTATION, CYCLOSPORINE-A, Physiology, Adrenergic beta-Antagonists, Angiotensin-Converting Enzyme Inhibitors, renin-angiotensin system, Fawn-Hooded rat, Pharmacology, Tacrolimus, DIABETIC-NEPHROPATHY, Nephrotoxicity, Internal medicine, Renin–angiotensin system, calcineurin inhibitor, Internal Medicine, medicine, Perindopril, Animals, VASCULAR DYSFUNCTION, CONVERTING ENZYME-INHIBITION, Amlodipine, business.industry, Calcineurin, nephrotoxicity, Glomerulosclerosis, Acute Kidney Injury, Calcium Channel Blockers, medicine.disease, Angiotensin II, Diet, Rats, END-ORGAN DAMAGE, Blood pressure, Losartan, Endocrinology, ANTIHYPERTENSIVE THERAPY, GLOMERULAR INJURY, Cardiology and Cardiovascular Medicine, business, Angiotensin II Type 1 Receptor Blockers, Immunosuppressive Agents, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b67491adf8d32d5ea379c6b961d122c4
https://doi.org/10.1038/hr.2014.79

3

Pioglitazone, a PPARγ agonist, provides comparable protection to angiotensin converting enzyme inhibitor ramipril against adriamycin nephropathy in rat

المؤلفون: Jan Klimas, Jan Kyselovic, Hana Cernecka, Peter Krenek, Robert H. Henning, Richard P. E. van Dokkum, Lucia Mesarosova, Peter Ochodnicky, Maaike Goris

المساهمون: Extramural researchers, Groningen Kidney Center (GKC), Vascular Ageing Programme (VAP), Groningen Institute for Organ Transplantation (GIOT)

المصدر: European journal of pharmacology, 730, 51-60. Elsevier
European Journal of Pharmacology, 730, 51-60. ELSEVIER SCIENCE BV

مصطلحات موضوعية: Male, ACE inhibitors, Kidney Glomerulus, DIABETIC-RATS, Adriamycin nephropathy, Angiotensin-Converting Enzyme Inhibitors, Blood Pressure, Pharmacology, Diabetic nephropathy, Ramipril, Chronic kidney disease, Aorta, Kidney, biology, Proteinuria, Kidney Tubules, medicine.anatomical_structure, ACTIVATED-RECEPTOR-GAMMA, Disease Progression, Kidney Diseases, Renin-angiotensin system, medicine.drug, medicine.medical_specialty, ENDOTHELIAL FUNCTION, PPAR gamma agonists, Nephropathy, MESANGIAL CELLS, Internal medicine, Renin–angiotensin system, medicine, INJURY, Animals, Rats, Wistar, Pioglitazone, business.industry, Angiotensin-converting enzyme, medicine.disease, NEPHROTIC RATS, Rats, PPAR gamma, MODEL, Endocrinology, RENAL DAMAGE, Gene Expression Regulation, MYOCARDIAL-INFARCTION, Doxorubicin, ACE inhibitor, biology.protein, THIAZOLIDINEDIONES, Endothelium, Vascular, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abdec833a7a03ca0f0b95c49f46aaf77
https://doi.org/10.1016/j.ejphar.2014.02.023

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4

Renal myogenic constriction protects the kidney from age-related hypertensive renal damage in the Fawn-Hooded rat

المؤلفون: Richard P. E. van Dokkum, Sjoerd W. Landheer, Robert H. Henning, Maaike Goris, Peter Vavrinec, Hendrik Buikema

المساهمون: Groningen University Institute for Drug Exploration (GUIDE), Groningen Kidney Center (GKC), Vascular Ageing Programme (VAP), Groningen Institute for Organ Transplantation (GIOT)

المصدر: Journal of Hypertension, 31(8), 1637-1645. LIPPINCOTT WILLIAMS & WILKINS

مصطلحات موضوعية: Male, Time Factors, FUNCTION PREDICTS, Physiology, medicine.medical_treatment, Kidney Glomerulus, Blood Pressure, SUSCEPTIBILITY, Kidney, urologic and male genital diseases, Phenylephrine, Renal Artery, myogenic constriction, Mesenteric arteries, Proteinuria, NEPHRECTOMY, Glomerulosclerosis, Focal Segmental, fawn-hooded rat, MESENTERIC-ARTERIES, Nephrectomy, medicine.anatomical_structure, Hypertension, HEART-FAILURE, Kidney Diseases, Hypotension, medicine.symptom, Cardiology and Cardiovascular Medicine, medicine.medical_specialty, PRESSURE, Renal Circulation, Constriction, Internal medicine, medicine.artery, Internal Medicine, medicine, Animals, Renal artery, BLOOD-FLOW, business.industry, aging, SIGNALING MECHANISMS, Rats, Disease Models, Animal, Blood pressure, Endocrinology, MYOCARDIAL-INFARCTION, Renal blood flow, GLOMERULAR INJURY, Kidney Failure, Chronic, proteinuria, business, chronic kidney disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5730f8c8e2bf4c5d0fee906f7e6b0116
https://doi.org/10.1097/hjh.0b013e328361d506

5

Epidermal growth factor receptor inhibitor PKI-166 governs cardiovascular protection without beneficial effects on the kidney in hypertensive 5/6 nephrectomized rats

المؤلفون: Gemma M. Mulder, Nadir Ulu, Sjoerd W. Landheer, Maaike Goris, Hakan Gurdal, Robert H. Henning, Basak Duman-Dalkilic, Hendrik Buikema, M Duin, Richard P. E. van Dokkum, Harry van Goor, Peter Vavrinec

المساهمون: Groningen Institute for Organ Transplantation (GIOT), Groningen Kidney Center (GKC), Vascular Ageing Programme (VAP)

المصدر: Journal of Pharmacology and Experimental Therapeutics, 345(3), 393-403. WILLIAMS & WILKINS

مصطلحات موضوعية: Male, CELL HYPERTROPHY, Hypertension, Renal, Angiotensin-Converting Enzyme Inhibitors, Aorta, Thoracic, Blood Pressure, Kidney, Nephrectomy, Muscle, Smooth, Vascular, Muscle hypertrophy, Lisinopril, RESISTANCE VESSELS, CARDIAC-HYPERTROPHY, Immunohistochemistry, Mesenteric Arteries, ErbB Receptors, Proteinuria, ANGIOTENSIN-II, medicine.anatomical_structure, Muscle Tonus, MYOGENIC CONSTRICTION, Molecular Medicine, HEART-FAILURE, EGF-RECEPTOR, medicine.drug, Muscle Contraction, Cardiac function curve, medicine.medical_specialty, Cardiotonic Agents, Renal function, Receptor, Angiotensin, Type 1, DIABETIC-NEPHROPATHY, EJECTION FRACTION, Internal medicine, Receptors, Adrenergic, alpha-1, medicine, Animals, Pyrroles, Rats, Wistar, EXPERIMENTAL RENAL-FAILURE, Pharmacology, business.industry, Glomerulosclerosis, medicine.disease, Angiotensin II, Rats, Endocrinology, Pyrimidines, Heart failure, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::519590fdc5fa6d86f3fd770d068d6479
https://doi.org/10.1124/jpet.113.203497

6

Vascular smooth muscle function of renal glomerular and interlobar arteries predicts renal damage in rats

المؤلفون: Peter Vavrinec, Maaike Goris, Hendrik Buikema, Richard P. E. van Dokkum, Robert H. Henning, Diana Vavrincova-Yaghi

المساهمون: Groningen University Institute for Drug Exploration (GUIDE), Groningen Kidney Center (GKC), Vascular Ageing Programme (VAP), Groningen Institute for Organ Transplantation (GIOT)

المصدر: American journal of physiology-Renal physiology, 303(8), F1187-F1195. AMER PHYSIOLOGICAL SOC

مصطلحات موضوعية: Male, Vascular smooth muscle, Physiology, medicine.medical_treatment, Kidney Glomerulus, renal vascular smooth muscle, renal damage, Blood Pressure, Kidney, urologic and male genital diseases, Muscle, Smooth, Vascular, Phenylephrine, Renal Artery, predictive value of vascular function, myogenic constriction, Vasoconstrictor Agents, Receptor, Mesenteric arteries, in vivo microscopy, NEPHRECTOMY, Renal damage, 5/6 nephrectomy, ANG II type 1 receptor, MESENTERIC-ARTERIES, Nephrectomy, Proteinuria, ANGIOTENSIN-II, medicine.anatomical_structure, HEART-FAILURE, Kidney Diseases, medicine.medical_specialty, IN-VIVO VISUALIZATION, ENDOTHELIAL FUNCTION, Urology, Renal Circulation, Internal medicine, medicine, Animals, Rats, Wistar, INDIVIDUAL SUSCEPTIBILITY, RECEPTOR, business.industry, medicine.disease, Interlobar arteries, AT(1), Angiotensin II, Acetylcholine, Rats, Endocrinology, Vasoconstriction, Heart failure, Endothelium, Vascular, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a765f8af3f7c5daa89872f49fa8e5a9
https://doi.org/10.1152/ajprenal.00653.2011

7

Losartan protects mesenteric arteries from ROS-associated decrease in myogenic constriction following 5/6 nephrectomy

المؤلفون: Robert H. Henning, Maaike Goris, Hendrik Buikema, Peter Vavrinec, Richard P. E. van Dokkum

المساهمون: Groningen University Institute for Drug Exploration (GUIDE), Vascular Ageing Programme (VAP), Groningen Kidney Center (GKC), Groningen Institute for Organ Transplantation (GIOT)

المصدر: Journal of the Renin-Angiotensin-Aldosterone System, Vol 12 (2011)
Journal of the Renin-Angiotensin-Aldosterone System, 12(3), 184-194

مصطلحات موضوعية: Male, Medicine (General), losartan, Blood Pressure, Kidney, Nephrectomy, Endocrinology, myogenic constriction, oxidative stress, SUPEROXIDE-DISMUTASE, Endothelial dysfunction, Mesenteric arteries, HYPERPOLARIZING FACTOR, Free Radical Scavengers, Mesenteric Arteries, Vasodilation, Losartan, medicine.anatomical_structure, HEART-FAILURE, Muscle Contraction, medicine.drug, medicine.medical_specialty, mesenteric artery, TONE, Endothelium, In Vitro Techniques, Protective Agents, RESISTANCE ARTERIES, Constriction, R5-920, Internal medicine, Internal Medicine, medicine, Chronic renal failure, Animals, Rats, Wistar, SPONTANEOUSLY HYPERTENSIVE-RATS, business.industry, medicine.disease, Angiotensin II, Acetylcholine, Rats, Blood pressure, RENAL DAMAGE, Vasoconstriction, Heart failure, ENDOTHELIAL DYSFUNCTION, Endothelium, Vascular, Reactive Oxygen Species, business, POSTERIOR CEREBRAL-ARTERIES

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc9b37400fe6e393dd34bb640324c3fe
https://hdl.handle.net/11370/23ac85c8-551e-48ca-887c-180c76cef8b7

8

Renal vascular dysfunction precedes the development of renal damage in the hypertensive Fawn-Hooded rat

المؤلفون: Dick de Zeeuw, Peter Ochodnický, Richard P. E. van Dokkum, Robert H. Henning, Abraham P. Provoost, Hendrik Buikema

المساهمون: Groningen University Institute for Drug Exploration (GUIDE), Groningen Kidney Center (GKC), Vascular Ageing Programme (VAP), Groningen Institute for Organ Transplantation (GIOT), Other departments

المصدر: American journal of physiology-Renal physiology, 298(3), F625-F633. AMER PHYSIOLOGICAL SOC
American journal of physiology. Renal physiology, 298(3), F625-F633. American Physiological Society

مصطلحات موضوعية: Male, Aging, FUNCTION PREDICTS, Physiology, Vasodilator Agents, Aorta, Thoracic, Blood Pressure, Fawn-Hooded rat, Kidney, endothelial dysfunction, prostaglandins, Diabetic nephropathy, Biological Factors, Renal Artery, Vasoconstrictor Agents, Endothelial dysfunction, HYPERPOLARIZING FACTOR, Age Factors, GLOMERULAR HYPERFILTRATION, Vasodilation, Proteinuria, medicine.anatomical_structure, Disease Progression, Kidney Diseases, Glomerular hyperfiltration, medicine.medical_specialty, myogenic response, hypertension, Endothelium, Urinary system, Myogenic contraction, Renal Circulation, DIABETIC-NEPHROPATHY, Constriction, nitric oxide, ENDOTHELIUM-DEPENDENT CONTRACTIONS, Internal medicine, medicine, Animals, INDIVIDUAL SUSCEPTIBILITY, NITRIC-OXIDE, Dose-Response Relationship, Drug, BLOOD-FLOW, business.industry, Membrane Proteins, Rats, Inbred Strains, medicine.disease, Rats, Disease Models, Animal, Endocrinology, MYOCARDIAL-INFARCTION, Vasoconstriction, Cyclooxygenase 1, IMPAIRED AUTOREGULATION, endothelium-derived hyperpolarizing factor, Endothelium, Vascular, business, chronic kidney disease, Kidney disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::825b99c1abdd63c2a853b499ccfcc2c3
https://doi.org/10.1152/ajprenal.00289.2009

9

Possible new druggable targets for the treatment of nephrosis

المؤلفون: Richard P. E. van Dokkum, Hendrik Buikema

المصدر: Current Opinion in Pharmacology. 9:132-138

مصطلحات موضوعية: Pharmacology, Communicable disease, Nephrosis, Biology, medicine.disease, Angiotensin II, Nephrotoxicity, Diabetic nephropathy, Caveolae, Drug Discovery, Immunology, Cancer research, medicine, Endothelial dysfunction, Kidney disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bf8ebc498424071f3ed126bd808986fd
https://doi.org/10.1016/j.coph.2008.12.008

View record from ScienceDirect

Full Text via ClinicalKey

10

Myocardial infarction does not further impair renal damage in 5/6 nephrectomized rats

المؤلفون: Ying Xu, Robert H. Henning, Willemijn A.K.M. Windt, Richard P. E. van Dokkum, Dick de Zeeuw, Alex C. A. Kluppel

المساهمون: Groningen University Institute for Drug Exploration (GUIDE), Groningen Kidney Center (GKC), Vascular Ageing Programme (VAP), Groningen Institute for Organ Transplantation (GIOT)

المصدر: Nephrology Dialysis Transplantation, 23(10), 3103-3110. Oxford University Press

مصطلحات موضوعية: Male, medicine.medical_specialty, CORONARY-ARTERY, medicine.medical_treatment, Urology, ACE-INHIBITORS, Renal function, Angiotensin-Converting Enzyme Inhibitors, Nephrectomy, Renin-Angiotensin System, CARDIAC-FUNCTION, INSUFFICIENCY, Lisinopril, Internal medicine, CARDIOVASCULAR RISK-FACTORS, medicine, Animals, Renal Insufficiency, Myocardial infarction, Rats, Wistar, UREMIC RATS, GENERAL-POPULATION, Transplantation, Kidney, ACEi therapy, 5/6 nephrectomy, business.industry, Hemodynamics, CONSCIOUS RATS, Glomerulosclerosis, URINARY ALBUMIN EXCRETION, medicine.disease, Rats, myocardial infarction, medicine.anatomical_structure, Endocrinology, Nephrology, Creatinine, Renal blood flow, HEART-FAILURE, cardiorenal interaction, Hemodialysis, business, Kidney disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e872820eab6d16aac59322bc81d9dd64
https://doi.org/10.1093/ndt/gfn233

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