يعرض 1 - 10 نتائج من 24 نتيجة بحث عن '"Riin, Reimets"', وقت الاستعلام: 0.81s تنقيح النتائج
  1. 1
    دورية أكاديمية
    Treatment with the dual-incretin agonist DA-CH5 demonstrates potent therapeutic effect in a rat model of Wolfram Syndrome

    المؤلفون: Toomas Jagomäe, Nayana Gaur, Kadri Seppa, Riin Reimets, Marko Pastak, Mihkel Plaas, Allen Kaasik, Eero Vasar, Mario Plaas

    المصدر: Frontiers in Endocrinology, Vol 14 (2023)

    مصطلحات موضوعية: wolfram (DIDMOAD) syndrome, incretin mimetics, glucose intolerance, dual incretins, animal models - rodent, Wfs1, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

    وصف الملف: electronic resource

    Relation: https://www.frontiersin.org/articles/10.3389/fendo.2023.1234925/full; https://doaj.org/toc/1664-2392

    URL الوصول: https://doaj.org/article/837495d36ff5427582528fa2621ac92c

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  2. 2
    دورية أكاديمية
    Chronic Stress Alters Hippocampal Renin-Angiotensin-Aldosterone System Component Expression in an Aged Rat Model of Wolfram Syndrome

    المؤلفون: Marite Punapart, Riin Reimets, Kadri Seppa, Silvia Kirillov, Nayana Gaur, Kattri-Liis Eskla, Toomas Jagomäe, Eero Vasar, Mario Plaas

    المصدر: Genes, Vol 14, Iss 4, p 827 (2023)

    مصطلحات موضوعية: Wolfram syndrome, Wfs1 knock-out, GLP1-R agonist, liraglutide, 7,8-DHF, RAAS, Genetics, QH426-470

    وصف الملف: electronic resource

    Relation: https://www.mdpi.com/2073-4425/14/4/827; https://doaj.org/toc/2073-4425

    URL الوصول: https://doaj.org/article/3aba092fd1c142b2a368817bfa8a9828

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  3. 3
    دورية أكاديمية
    Liraglutide, 7,8-DHF and their co-treatment prevents loss of vision and cognitive decline in a Wolfram syndrome rat model

    المؤلفون: Kadri Seppa, Toomas Jagomäe, Kaia Grete Kukker, Riin Reimets, Marko Pastak, Eero Vasar, Anton Terasmaa, Mario Plaas

    المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)

    مصطلحات موضوعية: Medicine, Science

    وصف الملف: electronic resource

    Relation: https://doaj.org/toc/2045-2322

    URL الوصول: https://doaj.org/article/e93aa6c7d66f4066a7c2017128bcf2ce

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  4. 4
    دورية أكاديمية
    Early Intervention and Lifelong Treatment with GLP1 Receptor Agonist Liraglutide in a Wolfram Syndrome Rat Model with an Emphasis on Visual Neurodegeneration, Sensorineural Hearing Loss and Diabetic Phenotype

    المؤلفون: Toomas Jagomäe, Kadri Seppa, Riin Reimets, Marko Pastak, Mihkel Plaas, Miriam A. Hickey, Kaia Grete Kukker, Lieve Moons, Lies De Groef, Eero Vasar, Allen Kaasik, Anton Terasmaa, Mario Plaas

    المصدر: Cells, Vol 10, Iss 11, p 3193 (2021)

    مصطلحات موضوعية: wolfram syndrome, Wfs1, GLP1 receptor agonist, liraglutide, rat model, neurodegeneration, Cytology, QH573-671

    وصف الملف: electronic resource

    Relation: https://www.mdpi.com/2073-4409/10/11/3193; https://doaj.org/toc/2073-4409

    URL الوصول: https://doaj.org/article/baf6b0dceefa49f8af4e77d5cbd8b3b4

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  5. 5
    دورية أكاديمية
    The Expression of RAAS Key Receptors, Agtr2 and Bdkrb1, Is Downregulated at an Early Stage in a Rat Model of Wolfram Syndrome

    المؤلفون: Marite Punapart, Kadri Seppa, Toomas Jagomäe, Mailis Liiv, Riin Reimets, Silvia Kirillov, Allen Kaasik, Lieve Moons, Lies De Groef, Anton Terasmaa, Eero Vasar, Mario Plaas

    المصدر: Genes, Vol 12, Iss 11, p 1717 (2021)

    مصطلحات موضوعية: Wolfram syndrome, Wfs1, Wfs1 knock-out, liraglutide, valproic acid, RAAS, Genetics, QH426-470

    وصف الملف: electronic resource

    Relation: https://www.mdpi.com/2073-4425/12/11/1717; https://doaj.org/toc/2073-4425

    URL الوصول: https://doaj.org/article/90b4cfbac9b54ca78c5c3be13cf21805

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  6. 6
    دورية أكاديمية
    High-Fat Diet Induces Pre-Diabetes and Distinct Sex-Specific Metabolic Alterations in Negr1-Deficient Mice

    المؤلفون: Maria Kaare, Kaie Mikheim, Kersti Lilleväli, Kalle Kilk, Toomas Jagomäe, Este Leidmaa, Maria Piirsalu, Rando Porosk, Katyayani Singh, Riin Reimets, Egon Taalberg, Michael K. E. Schäfer, Mario Plaas, Eero Vasar, Mari-Anne Philips

    المصدر: Biomedicines, Vol 9, Iss 9, p 1148 (2021)

    مصطلحات موضوعية: Negr1, obesity, metabolic disease, metabolomics, glucose intolerance, genetic models, Biology (General), QH301-705.5

    وصف الملف: electronic resource

    Relation: https://www.mdpi.com/2227-9059/9/9/1148; https://doaj.org/toc/2227-9059

    URL الوصول: https://doaj.org/article/3fa39a5f9bad4a3b8a594aac064199b7

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  7. 7
    Liraglutide, 7,8-DHF and their co-treatment prevents loss of vision and cognitive decline in a Wolfram syndrome rat model

    المؤلفون: Marko Pastak, Toomas Jagomäe, Eero Vasar, Anton Terasmaa, Kaia Grete Kukker, Riin Reimets, Mario Plaas, Kadri Seppa

    المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
    Scientific Reports

    مصطلحات موضوعية: Blood Glucose, Male, Visual acuity, Metabolic disorders, Visual Acuity, Morris water navigation task, Blindness, Hippocampus, Gene Knockout Techniques, Medicine, Cognitive decline, Multidisciplinary, Neurodegenerative diseases, Neurodegeneration, Fasting, Neural ageing, Optic nerve diseases, Disease Progression, Drug Therapy, Combination, medicine.symptom, medicine.drug, Agonist, medicine.medical_specialty, Wolfram syndrome, medicine.drug_class, Science, Molecular neuroscience, Neuroprotection, Article, Glucagon-Like Peptide-1 Receptor, Learning and memory, Internal medicine, Animals, Learning, Cognitive Dysfunction, Regeneration and repair in the nervous system, business.industry, Liraglutide, Body Weight, Membrane Proteins, Optic Nerve, Wolfram Syndrome, Flavones, medicine.disease, Rats, Disease Models, Animal, Endocrinology, Gene Expression Regulation, Remyelination, Hyperglycemia, Nerve Degeneration, Diseases of the nervous system, Calmodulin-Binding Proteins, business, Biomarkers, Neurological disorders

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fc83a2c86b97176c56f10fad51b6900
    https://doaj.org/article/e93aa6c7d66f4066a7c2017128bcf2ce

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  8. 8
    The Expression of RAAS Key Receptors, Agtr2 and Bdkrb1, Is Downregulated at an Early Stage in a Rat Model of Wolfram Syndrome

    المؤلفون: Eero Vasar, Lies De Groef, Lieve Moons, Toomas Jagomäe, Anton Terasmaa, Allen Kaasik, Kadri Seppa, Marite Punapart, Mario Plaas, Mailis Liiv, Silvia Kirillov, Riin Reimets

    المصدر: Genes
    Volume 12
    Issue 11
    Genes, Vol 12, Iss 1717, p 1717 (2021)

    مصطلحات موضوعية: Agonist, medicine.medical_specialty, Wolfram syndrome, medicine.drug_class, Bdkrb1, Bradykinin, QH426-470, Wfs1 knock-out, chemistry.chemical_compound, RAAS, valproic acid, Internal medicine, Gene expression, Genetics, medicine, Receptor, Genetics (clinical), liraglutide, Aldosterone, aldosterone, business.industry, medicine.disease, Angiotensin II, Wfs1, Pathophysiology, Endocrinology, chemistry, Agtr2, bradykinin, business

    وصف الملف: application/pdf; Electronic

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acc418299cdd5384707a5b9ff5a67086

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  9. 9
    Early intervention and lifelong treatment with GLP1 receptor agonist liraglutide in a Wolfram Syndrome rat model with an emphasis on visual neurodegeneration, sensorineural hearing loss and diabetic phenotype

    المؤلفون: Eero Vasar, Lieve Moons, Lies De Groef, Anton Terasmaa, Toomas Jagomäe, Kadri Seppa, Miriam A Hickey, Marko Pastak, Allen Kaasik, Mario Plaas, Kaia Grete Kukker, Riin Reimets, Mihkel Plaas

    المصدر: Cells
    Volume 10
    Issue 11
    Cells, Vol 10, Iss 3193, p 3193 (2021)

    مصطلحات موضوعية: Male, Agonist, medicine.medical_specialty, visual acuity, QH301-705.5, medicine.drug_class, Wolfram syndrome, Hearing loss, Hearing Loss, Sensorineural, wolfram syndrome, Gastroenterology, Neuroprotection, Glucagon-Like Peptide-1 Receptor, Article, Diabetes Mellitus, Experimental, GLP1 receptor agonist, Internal medicine, Diabetes mellitus, medicine, Animals, Visual Pathways, Biology (General), hearing loss, liraglutide, C-Peptide, diabetes, business.industry, Liraglutide, rat model, neurodegeneration, Optic Nerve, optic nerve atrophy, General Medicine, medicine.disease, Wfs1, Rats, Disease Models, Animal, Phenotype, Nerve Degeneration, Diabetes insipidus, Sensorineural hearing loss, medicine.symptom, business, medicine.drug

    وصف الملف: Electronic; application/pdf

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::866af3166e63f3cab2515be86b4387ae
    https://doi.org/10.21203/rs.3.rs-903256/v1

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  10. 10
    GLP-1 receptor agonist liraglutide has a neuroprotective effect on an aged rat model of Wolfram syndrome

    المؤلفون: Mario Plaas, Maia Pallase, Anton Terasmaa, Riin Reimets, Kadri Seppa, Stine Hasselholt, Tuuliki Koppel, Jens R. Nyengaard, Eero Vasar, Toomas Jagomäe, Maarja Toots, Maiken Krogsbæk Mikkelsen

    المصدر: Seppa, K, Toots, M, Reimets, R, Jagomäe, T, Koppel, T, Pallase, M, Hasselholt, S, Krogsbæk Mikkelsen, M, Randel Nyengaard, J, Vasar, E, Terasmaa, A & Plaas, M 2019, ' GLP-1 receptor agonist liraglutide has a neuroprotective effect on an aged rat model of Wolfram syndrome ', Scientific Reports, vol. 9, no. 1, 15742 . https://doi.org/10.1038/s41598-019-52295-2
    Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
    Scientific Reports

    مصطلحات موضوعية: Male, Retinal Ganglion Cells, 0301 basic medicine, Agonist, medicine.medical_specialty, Wolfram syndrome, medicine.drug_class, lcsh:Medicine, Apoptosis, Retinal ganglion, Neuroprotection, Glucagon-Like Peptide-1 Receptor, Article, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Animals, Medicine, Neurodegeneration, lcsh:Science, Glucagon-like peptide 1 receptor, Neurons, Multidisciplinary, Molecular medicine, business.industry, Liraglutide, lcsh:R, Membrane Proteins, Endocrine system and metabolic diseases, Optic Nerve, Wolfram Syndrome, Glucose Tolerance Test, Endoplasmic Reticulum Stress, medicine.disease, Rats, Disease Models, Animal, Neuroprotective Agents, 030104 developmental biology, Endocrinology, Hyperglycemia, Optic nerve, Calmodulin-Binding Proteins, lcsh:Q, Rats, Transgenic, business, 030217 neurology & neurosurgery, medicine.drug

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b5cbf6ba5c0382a57311b721345e31c
    https://pure.au.dk/portal/da/publications/glp1-receptor-agonist-liraglutide-has-a-neuroprotective-effect-on-an-aged-rat-model-of-wolfram-syndrome(a8bf7ec7-f827-45aa-baa7-ba3958c7cb97).html

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