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1دورية أكاديمية
المؤلفون: Elisa Greggio, Shushant Jain, Ann Kingsbury, Rina Bandopadhyay, Patrick Lewis, Alice Kaganovich, Marcel P. van der Brug, Alexandra Beilina, Jeff Blackinton, Kelly Jean Thomas, Rili Ahmad, David W. Miller, Sashi Kesavapany, Andrew Singleton, Andrew Lees, Robert J. Harvey, Kirsten Harvey, Mark R. Cookson
المصدر: Neurobiology of Disease, Vol 23, Iss 2, Pp 329-341 (2006)
مصطلحات موضوعية: LRRK2, Kinase, Parkinson's disease, α-Synuclein, Substantia nigra, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: Anna Sandebring, Kelly Jean Thomas, Alexandra Beilina, Marcel van der Brug, Megan M Cleland, Rili Ahmad, David W Miller, Ibardo Zambrano, Richard F Cowburn, Homira Behbahani, Angel Cedazo-Mínguez, Mark R Cookson
المصدر: PLoS ONE, Vol 4, Iss 5, p e5701 (2009)
وصف الملف: electronic resource
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المؤلفون: Jeff Blackinton, Marcel P. van der Brug, Mark R. Cookson, Andrew J. Lees, Lars Olson, Rili Ahmad, Rina Bandopadhyay, Ravindran Kumaran, Dagmar Galter
المصدر: Neuroscience Letters. 452:8-11
مصطلحات موضوعية: medicine.medical_specialty, Protein Deglycase DJ-1, Biology, Article, Proto-Oncogene Proteins, Internal medicine, Translational regulation, medicine, Humans, Immunoprecipitation, Electrophoresis, Gel, Two-Dimensional, Protein Phosphatase 2, RNA, Messenger, RNA Processing, Post-Transcriptional, Gene, Post-transcriptional regulation, Adaptor Proteins, Signal Transducing, Oncogene Proteins, Glutathione Peroxidase, Messenger RNA, General Neuroscience, Parkinsonism, Intracellular Signaling Peptides and Proteins, Brain, RNA, NADH Dehydrogenase, Parkinson Disease, Selenoprotein W, Phospholipid Hydroperoxide Glutathione Peroxidase, medicine.disease, Molecular biology, Endocrinology, bcl-Associated Death Protein
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المؤلفون: J. Raphael Gibbs, Nancy M. Bonini, Huaibin Cai, Myriam Gorospe, Chengsong Xie, Ashish Lal, Jeff Blackinton, Jayanth Chandran, Alexandra Beilina, Marcel P. van der Brug, Jinhui Ding, Amanda J. Myers, Ling Yang Hao, Kelly Jean Thomas, Ming Zhan, Rili Ahmad, Mark R. Cookson, Krystyna Mazan-Mamczarz, Jennifer L. Martindale
المصدر: Proceedings of the National Academy of Sciences. 105:10244-10249
مصطلحات موضوعية: MAP Kinase Signaling System, Molecular Sequence Data, Protein Deglycase DJ-1, Genes, Recessive, RNA-binding protein, Mitochondrion, Biology, Transfection, medicine.disease_cause, Cell Line, Mice, Phosphatidylinositol 3-Kinases, Parkinsonian Disorders, Gene expression, medicine, Animals, Drosophila Proteins, Humans, RNA, Messenger, RNA, Small Interfering, Gene, Mice, Knockout, Oncogene Proteins, Genetics, Multidisciplinary, Base Sequence, Parkinsonism, Intracellular Signaling Peptides and Proteins, PTEN Phosphohydrolase, Brain, RNA-Binding Proteins, RNA, Peroxiredoxins, Biological Sciences, medicine.disease, Glutathione, Recombinant Proteins, Cell biology, Oxidative Stress, Genes, Mitochondrial, Drosophila, Oxidative stress
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7e6ccd9151e698fdf2222d26094597c
https://doi.org/10.1073/pnas.0708518105 -
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المؤلفون: Alice Kaganovich, Elisa Greggio, Andrew J. Lees, Jeff Blackinton, Alexandra Beilina, Robert J. Harvey, Kirsten Harvey, Sashi Kesavapany, Rina Bandopadhyay, Andrew B. Singleton, Ann E. Kingsbury, Kelly Jean Thomas, David Miller, Patrick A. Lewis, Mark R. Cookson, Shushant Jain, Rili Ahmad, Marcel P. van der Brug
المصدر: Neurobiology of Disease, Vol 23, Iss 2, Pp 329-341 (2006)
مصطلحات موضوعية: Kinase, DNA, Complementary, Parkinson's disease, Mutant, Protein Serine-Threonine Kinases, Biology, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Inclusion bodies, lcsh:RC321-571, chemistry.chemical_compound, Mutant protein, Substantia nigra, Humans, Phosphorylation, Kinase activity, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Inclusion Bodies, Genetics, LRRK2 Gene, Alpha-synuclein, α-Synuclein, Reverse Transcriptase Polymerase Chain Reaction, Brain, Parkinson Disease, LRRK2, Immunohistochemistry, Amino Acid Substitution, Neurology, Protein kinase domain, chemistry, Mutation
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe1746147630676cc924458324ecac07
http://www.sciencedirect.com/science/article/pii/S0969996106000714 -
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المؤلفون: Alexandra Beilina, David Miller, Sashi Kesavapany, Mark R. Cookson, Marcel P. van der Brug, Gregory A. Petsko, Rili Ahmad
المصدر: Proceedings of the National Academy of Sciences. 102:5703-5708
مصطلحات موضوعية: Models, Molecular, Recombinant Fusion Proteins, MAP3K7, Cell Line, MAP2K7, Parkinsonian Disorders, Chlorocebus aethiops, Enzyme Stability, Animals, Humans, Point Mutation, c-Raf, Kinase activity, Multidisciplinary, biology, Cyclin-dependent kinase 4, Cyclin-dependent kinase 2, Middle Aged, Biological Sciences, Protein kinase R, Molecular biology, Mitochondria, Protein Structure, Tertiary, COS Cells, biology.protein, Cyclin-dependent kinase 7, Protein Kinases, Protein Processing, Post-Translational
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66592c8d5dba93176a81d3f4e16f702d
https://doi.org/10.1073/pnas.0500617102 -
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المؤلفون: Rosa M. Canet-Avilés, Mona Kaleem, Marcel P. van der Brug, David Miller, Stephen Hague, Rili Ahmad, Jeff Blackinton, Mark R. Cookson
المصدر: Molecular Brain Research. 134:76-83
مصطلحات موضوعية: Models, Molecular, Time Factors, Blotting, Western, Green Fluorescent Proteins, Protein Deglycase DJ-1, Fluorescent Antibody Technique, Oxidative phosphorylation, Cysteine Proteinase Inhibitors, Mitochondrion, Biology, Transfection, medicine.disease_cause, Ammonium Chloride, Mice, Neuroblastoma, Cellular and Molecular Neuroscience, Cell Line, Tumor, medicine, Animals, Humans, Immunoprecipitation, Point Mutation, RNA, Messenger, Cycloheximide, Molecular Biology, Gene, Oncogene Proteins, Protein Synthesis Inhibitors, Genetics, Analysis of Variance, Mutation, Polymorphism, Genetic, Reverse Transcriptase Polymerase Chain Reaction, Point mutation, Intracellular Signaling Peptides and Proteins, Subcellular localization, Molecular biology, Acetylcysteine, Gene Expression Regulation, Proteasome, Dimerization, Subcellular Fractions
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المؤلفون: Rili Ahmad, Stephen Hague, Gary R. Klinefelter, Chris McLendon, Jayanth Chandran, Mark R. Cookson, Julia Stadler, Rosa M. Canet-Avilés, David Miller, Melisa J. Baptista, Donald M. Carter, Peng-Peng Zhu, Craig Blackstone
المصدر: Journal of Biological Chemistry. 278:36588-36595
مصطلحات موضوعية: Proteasome Endopeptidase Complex, Blotting, Western, Green Fluorescent Proteins, Protein Deglycase DJ-1, Mutant, Genes, Recessive, Biology, Transfection, medicine.disease_cause, Biochemistry, Cell Line, Cytosol, Multienzyme Complexes, Two-Hybrid System Techniques, medicine, Animals, Humans, Point Mutation, Molecular Biology, Gene, Oncogene Proteins, Genetics, Chromatography, Mutation, Dose-Response Relationship, Drug, Reverse Transcriptase Polymerase Chain Reaction, Ubiquitin, Lysine, Point mutation, Intracellular Signaling Peptides and Proteins, Wild type, PARK7, Parkinson Disease, Cell Biology, Precipitin Tests, Mitochondria, Cysteine Endopeptidases, Luminescent Proteins, Microscopy, Fluorescence, Proteasome, COS Cells, Gene Deletion, Protein Binding, Subcellular Fractions
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31e89de256c93711b070bd9e66b0e8c8
https://doi.org/10.1074/jbc.m304272200 -
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المؤلفون: Rili Ahmad, Matthew J. Farrer, John Hardy, Mark R. Cookson, Casey O'Farrell, Sneha Daya, Melisa J. Baptista, David Miller
المصدر: Journal of Neurochemistry. 85:957-968
مصطلحات موضوعية: Regulation of gene expression, Tyrosine hydroxylase, Biology, Biochemistry, Molecular biology, Cellular and Molecular Neuroscience, Dopamine, Dopaminergic Cell, Gene expression, Transcriptional regulation, medicine, Sepiapterin reductase, Transcription factor, medicine.drug
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المؤلفون: Richard F. Cowburn, Marcel P. van der Brug, Homira Behbahani, Kelly Jean Thomas, Rili Ahmad, Ibardo Zambrano, Megan M. Cleland, Mark R. Cookson, Anna Sandebring, David Miller, Alexandra Beilina, Angel Cedazo-Minguez
المصدر: PLoS ONE
PLoS ONE, Vol 4, Iss 5, p e5701 (2009)مصطلحات موضوعية: Dynamins, Cell Survival, Cell Biology/Neuronal Signaling Mechanisms, lcsh:Medicine, PINK1, Mitochondrion, Biology, Mitochondrial apoptosis-induced channel, Models, Biological, Cell Line, GTP Phosphohydrolases, Mitochondrial Proteins, DNM1L, Rotenone, Humans, Phosphorylation, Inner mitochondrial membrane, lcsh:Science, Genetics and Genomics/Genetics of Disease, Neurological Disorders/Movement Disorders, Multidisciplinary, Kinase, Calcineurin, lcsh:R, Molecular biology, Cell biology, Mitochondria, Enzyme Activation, Phenotype, Gene Knockdown Techniques, DNAJA3, lcsh:Q, ATP–ADP translocase, Microtubule-Associated Proteins, Protein Kinases, Research Article