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المؤلفون: Michael R. Collins, Robert Steven Kania, Connie Fan, Sutton Scott Channing, Dominique Verhelle, Kephart Susan Elizabeth, Martin James Wythes, Shuiwang Wang, Karen A. Maegley, Lisa Nguyen, Daniel Tyler Richter, A.E. Stewart, Pei-Pei Kung, Buwen Huang, Shikhar Sharma, Shinji Yamazaki, Ya-Li Deng, Rita Grantner, Patrick Bingham, Robert Arnold Kumpf, Penney Khamphavong, Jinjiang Zhu, Dac M. Dinh, Manfred Kraus, Wei Liu, Sean Uryu, Jillian E. Spangler, Wenyue Hu, Hui Wang, Robert A. Rollins, Cody Krivacic, Zehnder Luke Raymond, Neal W. Sach, Alexei Brooun, John Sherrill, Shijian Ren, Martin A. Edwards, Huichun Zhu, Ketan S. Gajiwala, Shuibo Xin, Hovhannes J. Gukasyan
المصدر: Journal of Medicinal Chemistry. 61:650-665
مصطلحات موضوعية: 0301 basic medicine, Chemistry, Stereochemistry, Ligand (biochemistry), 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, In vivo, Drug Discovery, Lactam, Molecular Medicine, Moiety, Molecule, Solubility, Lead compound, ADME
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المؤلفون: Xiaoli Wang, Stephan Grant, Rita Grantner, Ben Bolaños, Casey L. Quinlan, Stephen E. Kaiser, Shannon Karlicek-Bryant, Stephen Jenkinson, Valeria R Fantin, Peter A. Wells, Jun Li Feng, Stephen Dann, Al E. Stewart, Nowlin Dawn Marie, Kevin Daniel Freeman-Cook
المصدر: Nature Chemical Biology. 13:785-792
مصطلحات موضوعية: 0301 basic medicine, S-Adenosylmethionine, Allosteric regulation, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Biosynthesis, Cell Line, Tumor, Humans, Binding site, Molecular Biology, chemistry.chemical_classification, Methionine, Dose-Response Relationship, Drug, biology, Active site, Methionine Adenosyltransferase, Cell Biology, Triazoles, Kinetics, 030104 developmental biology, Enzyme, Allosteric enzyme, chemistry, Biochemistry, Quinolines, biology.protein, Allosteric Site
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المؤلفون: Pei-Pei, Kung, Patrick, Bingham, Alexei, Brooun, Michael, Collins, Ya-Li, Deng, Dac, Dinh, Connie, Fan, Ketan S, Gajiwala, Rita, Grantner, Hovhannes J, Gukasyan, Wenyue, Hu, Buwen, Huang, Robert, Kania, Susan E, Kephart, Cody, Krivacic, Robert A, Kumpf, Penney, Khamphavong, Manfred, Kraus, Wei, Liu, Karen A, Maegley, Lisa, Nguyen, Shijian, Ren, Dan, Richter, Robert A, Rollins, Neal, Sach, Shikhar, Sharma, John, Sherrill, Jillian, Spangler, Albert E, Stewart, Scott, Sutton, Sean, Uryu, Dominique, Verhelle, Hui, Wang, Shuiwang, Wang, Martin, Wythes, Shuibo, Xin, Shinji, Yamazaki, Huichun, Zhu, JinJiang, Zhu, Luke, Zehnder, Martin, Edwards
المصدر: Journal of medicinal chemistry. 61(3)
مصطلحات موضوعية: Models, Molecular, Cell Line, Tumor, Drug Design, Molecular Conformation, Administration, Oral, Biological Availability, Humans, Enhancer of Zeste Homolog 2 Protein, Isoquinolines
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المؤلفون: Michael A. Grassi, Evgeny V. Berdyshev, Ravi Shah, Joseph Bogaard, Wenbo Mu, Dingcai Cao, Jerry J. White, Qing Chang, Rita Grantner, Sam Bettis, Siquan Chen
مصطلحات موضوعية: Programmed cell death, Light, Cell, Molecular Sequence Data, Drug Evaluation, Preclinical, Gene Expression, Photochemistry, Biochemistry, Neuroprotection, Cell Line, chemistry.chemical_compound, Mice, Cytochrome P-450 Enzyme System, Sulfaphenazole, Retinitis pigmentosa, medicine, Animals, Humans, Amino Acid Sequence, Gene Silencing, Cytochrome P450 Family 2, Molecular Biology, Cytochrome P-450 CYP2C9, biology, Cell Death, Cytochrome P450, Cell Biology, Monooxygenase, medicine.disease, medicine.anatomical_structure, chemistry, Apoptosis, Cytoprotection, biology.protein, Arachidonic acid, Aryl Hydrocarbon Hydroxylases, Sequence Alignment, Photoreceptor Cells, Vertebrate
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8b4c800acbd4fb0ea192552198b7ec7
https://europepmc.org/articles/PMC3961660/
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