المؤلفون: Roach, KM, Duffy, SM, Coward, W, Feghali-Bostwick, C, Wulff, H, Bradding, P

المصدر: PLoS ONE. 9(1)

مصطلحات موضوعية: General Science & Technology

URL الوصول: https://escholarship.org/uc/item/75c216d9

المؤلفون: Roach, KM, Duffy, SM, Coward, W, Feghali-Bostwick, C, Wulff, H, Bradding, P

المصدر: PLoS ONE. 8(12)

مصطلحات موضوعية: General Science & Technology

URL الوصول: https://escholarship.org/uc/item/7hm3t31q

المؤلفون: Allen, RJ, Oldham, JM, Jenkins, DA, Leavy, OC, Guillen-Guio, B, Melbourne, CA, Ma, S-F, Jou, J, Kim, JS, CleanUP-IPF Investigators of the Pulmonary Trials Cooperative, Fahy, WA, Oballa, E, Hubbard, RB, Navaratnam, V, Braybrooke, R, Saini, G, Roach, KM, Tobin, MD, Hirani, N, Whyte, MKB, Kaminski, N, Zhang, Y, Martinez, FJ, Linderholm, AL, Adegunsoye, A, Strek, ME, Maher, TM, Molyneaux, PL, Flores, C, Noth, I, Gisli Jenkins, R, Wain, LV

المصدر: Allen, R, Oldman, J, Jenkins, D A, Leavy, O, Flores, C, Noth, I, Jenkins, R G & Wain, L 2022, ' Longitudinal lung function and gas transfer in individuals with idiopathic pulmonary fibrosis: a genome-wide association study ', The Lancet Respiratory Medicine . https://doi.org/10.1016/S2213-2600(22)00251-X

مصطلحات موضوعية: Pulmonary and Respiratory Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2939e6a1928745deedb847557a47894
https://pubmed.ncbi.nlm.nih.gov/35985358

المؤلفون: Roach, KM, Castells, E, Dixon, K, Mason, S, Elliott, G, Marshall, H, Poblocka, MA, Macip, S, Richardson, M, Khalfaoui, L, Bradding, P

المصدر: Frontiers in Pharmacology; 10/12/2021, Vol. 12, p1-14, 14p

مصطلحات موضوعية: LUNGS, ION channels, GENE expression, IDIOPATHIC pulmonary fibrosis, LUNG diseases, MATRIX metalloproteinases, GROWTH factors

المؤلفون: Roach, KM, Feghali-Bostwick, C, Wulff, H, Amrani, Y, Bradding, P

المصدر: Roach, KM; Feghali-Bostwick, C; Wulff, H; Amrani, Y; & Bradding, P. (2015). Human lung myofibroblast TGFβ1-dependent Smad2/3 signalling is Ca2+-dependent and regulated by KCa3.1 K+ channels. Fibrogenesis and Tissue Repair, 8(1). doi: 10.1186/s13069-015-0022-0. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/42f9m2tr

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od_______325::17b75e4f8deef3af5dd1e829696df124
http://www.escholarship.org/uc/item/42f9m2tr

المؤلفون: Roach, KM, Wulff, H, Feghali-Bostwick, C, Amrani, Y, Bradding, P

المصدر: Roach, KM; Wulff, H; Feghali-Bostwick, C; Amrani, Y; & Bradding, P. (2014). Increased constitutive αSMA and Smad2/3 expression in idiopathic pulmonary fibrosis myofibroblasts is KCa3.1-dependent. Respiratory Research, 15(1), 155. doi: 10.1186/s12931-014-0155-5. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/4cb1z533

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od_______325::0fd5939fe4ae43bcbc71943142aef190
http://www.escholarship.org/uc/item/4cb1z533

المؤلفون: Roach, KM, Duffy, SM, Coward, W, Feghali-Bostwick, C, Wulff, H, Bradding, P

المصدر: Roach, KM; Duffy, SM; Coward, W; Feghali-Bostwick, C; Wulff, H; & Bradding, P. (2013). The K+channel KCa3.1 as a novel target for idiopathic pulmonary fibrosis. PLoS ONE, 8(12). doi: 10.1371/journal.pone.0085244. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/7hm3t31q

مصطلحات موضوعية: respiratory system, respiratory tract diseases

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od_______325::7a16f6bc97d3002077efdc3ad5aeafb1
http://www.escholarship.org/uc/item/7hm3t31q

المؤلفون: Allen RJ; Department of Health Sciences, University of Leicester, Leicester, UK. Electronic address: rja34@leicester.ac.uk., Oldham JM; Division of Pulmonary and Critical Care Medicine, University of Michigan, Ann Arbor, MI, USA., Jenkins DA; Division of Informatics, Imaging & Data Sciences, University of Manchester, Manchester, UK., Leavy OC; Department of Health Sciences, University of Leicester, Leicester, UK., Guillen-Guio B; Department of Health Sciences, University of Leicester, Leicester, UK., Melbourne CA; Department of Health Sciences, University of Leicester, Leicester, UK., Ma SF; Division of Pulmonary & Critical Care Medicine, University of Virginia, Charlottesville, VA, USA., Jou J; Department of Surgery, University of Illinois College of Medicine at Peoria, Peoria, IL, USA., Kim JS; Division of Pulmonary & Critical Care Medicine, University of Virginia, Charlottesville, VA, USA., Fahy WA; Discovery Medicine, GlaxoSmithKline, Stevenage, UK., Oballa E; Discovery Medicine, GlaxoSmithKline, Stevenage, UK., Hubbard RB; Division of Epidemiology and Public Health, University of Nottingham, Nottingham, UK; National Institute for Health Research, Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK., Navaratnam V; Division of Epidemiology and Public Health, University of Nottingham, Nottingham, UK; National Institute for Health Research, Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK; Queensland Lung Transplant Service, The Prince Charles Hospital, Brisbane, QLD, Australia., Braybrooke R; Division of Epidemiology and Public Health, University of Nottingham, Nottingham, UK; National Institute for Health Research, Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK., Saini G; Respiratory Medicine, Nottingham University Hospitals NHS Trust, Nottingham, UK., Roach KM; Department of Respiratory Sciences, University of Leicester, Glenfield Hospital, Leicester, UK., Tobin MD; Department of Health Sciences, University of Leicester, Leicester, UK., Hirani N; Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK., Whyte MKB; Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK., Kaminski N; Section of Pulmonary, Critical Care and Sleep Medicine, Yale School of Medicine, New Haven, CT, USA., Zhang Y; Division of Pulmonary, Allergy and Critical Care Medicine, The University of Pittsburgh, Pittsburgh, PA, USA., Martinez FJ; Division of Pulmonary and Critical Care Medicine, Weill Cornell Medicine, New York, NY, USA., Linderholm AL; Department of Internal Medicine, University of California Davis, Davis, CA, USA., Adegunsoye A; Section of Pulmonary and Critical Care Medicine, University of Chicago, Chicago, IL, USA., Strek ME; Section of Pulmonary and Critical Care Medicine, University of Chicago, Chicago, IL, USA., Maher TM; National Heart and Lung Institute, Imperial College London, London, UK; Royal Brompton and Harefield Hospitals, London, UK; Division of Pulmonary and Critical Care Medicine, University of Southern California, Los Angeles, CA, USA., Molyneaux PL; National Heart and Lung Institute, Imperial College London, London, UK; Royal Brompton and Harefield Hospitals, London, UK., Flores C; Research Unit, Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Spain; CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain; Genomics Division, Instituto Tecnológico y de Energías Renovables, Santa Cruz de Tenerife, Spain., Noth I; Division of Pulmonary & Critical Care Medicine, University of Virginia, Charlottesville, VA, USA., Gisli Jenkins R; National Heart and Lung Institute, Imperial College London, London, UK., Wain LV; Department of Health Sciences, University of Leicester, Leicester, UK; National Institute for Health Research, Leicester Respiratory Biomedical Research Centre, Glenfield Hospital, Leicester, UK.

مؤلفون مشاركون: CleanUP-IPF Investigators of the Pulmonary Trials Cooperative

المصدر: The Lancet. Respiratory medicine [Lancet Respir Med] 2023 Jan; Vol. 11 (1), pp. 65-73. Date of Electronic Publication: 2022 Aug 16.

نوع المنشور: Meta-Analysis; Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 101605555 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2619 (Electronic) Linking ISSN: 22132600 NLM ISO Abbreviation: Lancet Respir Med Subsets: MEDLINE

مواضيع طبية MeSH: Genome-Wide Association Study* , Idiopathic Pulmonary Fibrosis*/diagnosis, Humans ; Lung ; Vital Capacity ; Lung Volume Measurements

المؤلفون: Alzahrani A; Department of Respiratory Sciences, Clinical Sciences, University of Leicester, Glenfield Hospital, Leicester, United Kingdom.; Department of Applied Medical Sciences, Applied College, Albaha University, Albaha, Saudi Arabia., Hakeem J; Department of Respiratory Sciences, Clinical Sciences, University of Leicester, Glenfield Hospital, Leicester, United Kingdom., Biddle M; Department of Respiratory Sciences, Clinical Sciences, University of Leicester, Glenfield Hospital, Leicester, United Kingdom., Alhadian F; Department of Respiratory Sciences, Clinical Sciences, University of Leicester, Glenfield Hospital, Leicester, United Kingdom., Hussain A; Department of Respiratory Sciences, Clinical Sciences, University of Leicester, Glenfield Hospital, Leicester, United Kingdom., Khalfaoui L; Department of Respiratory Sciences, Clinical Sciences, University of Leicester, Glenfield Hospital, Leicester, United Kingdom., Roach KM; Department of Respiratory Sciences, Clinical Sciences, University of Leicester, Glenfield Hospital, Leicester, United Kingdom., Tliba O; Department of Biomedical Sciences, College of Veterinary Medicine, Long Island University, Brookville, NY, United States., Bradding P; Department of Respiratory Sciences, Clinical Sciences, University of Leicester, Glenfield Hospital, Leicester, United Kingdom., Amrani Y; Department of Respiratory Sciences, Clinical Sciences, University of Leicester, Glenfield Hospital, Leicester, United Kingdom.

المصدر: Frontiers in allergy [Front Allergy] 2021 Dec 29; Vol. 2, pp. 785100. Date of Electronic Publication: 2021 Dec 29 (Print Publication: 2021).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 9918227355906676 Publication Model: eCollection Cited Medium: Internet ISSN: 2673-6101 (Electronic) Linking ISSN: 26736101 NLM ISO Abbreviation: Front Allergy Subsets: PubMed not MEDLINE

المؤلفون: Virk HS; NIHR Respiratory BRC, Department of Respiratory Sciences, University of Leicester, Leicester, UK., Biddle MS; NIHR Respiratory BRC, Department of Respiratory Sciences, University of Leicester, Leicester, UK., Smallwood DT; School of Allied Health Sciences, De Montfort University, Leicester, UK., Weston CA; NIHR Respiratory BRC, Department of Respiratory Sciences, University of Leicester, Leicester, UK., Castells E; NIHR Respiratory BRC, Department of Respiratory Sciences, University of Leicester, Leicester, UK., Bowman VW; School of Allied Health Sciences, De Montfort University, Leicester, UK., McCarthy J; NIHR Respiratory BRC, Department of Respiratory Sciences, University of Leicester, Leicester, UK., Amrani Y; NIHR Respiratory BRC, Department of Respiratory Sciences, University of Leicester, Leicester, UK., Duffy SM; NIHR Respiratory BRC, Department of Respiratory Sciences, University of Leicester, Leicester, UK., Bradding P; NIHR Respiratory BRC, Department of Respiratory Sciences, University of Leicester, Leicester, UK., Roach KM; NIHR Respiratory BRC, Department of Respiratory Sciences, University of Leicester, Leicester, UK.

المصدر: British journal of pharmacology [Br J Pharmacol] 2021 Aug; Vol. 178 (15), pp. 2948-2962. Date of Electronic Publication: 2021 May 25.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Myofibroblasts*/metabolism , TRPA1 Cation Channel* , Transforming Growth Factor beta1*/metabolism, Apoptosis ; Down-Regulation ; Fibroblasts/metabolism ; HEK293 Cells ; Humans ; Lung/metabolism