المؤلفون: Schwalm MP, Berger LM, Meuter MN, Vasta JD, Corona CR, Röhm S, Berger BT, Farges F, Beinert SM, Preuss F, Morasch V, Rogov VV, Mathea S, Saxena K, Robers MB, Müller S, Knapp S.

المصدر: Front Cell Dev Biol.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=r3c4b2081b22::d12db7ff0cc277070fded33a2ed13d65

المؤلفون: Forster, M, Chaikuad, A, Bauer, SM, Holstein, J, Robers, MB, Corona, CR, Gehringer, M, Pfaffenrot, E, Ghoreschi, K, Knapp, S, Laufer, SA

المصدر: Cell Chemical Biology, 23 (11)
Cell Chemical Biology

مصطلحات موضوعية: Binding Sites, T-Lymphocytes, chemical probe, Janus Kinase 3, Brief Communication, kinome selectivity, Molecular Docking Simulation, covalent reversible inhibitor, Drug Discovery, Janus kinases, Humans, JAK3, Protein Kinase Inhibitors, Signal Transduction

وصف الملف: application/application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f7ee3c3020c7581505aea9d568fe0541

المؤلفون: Němec V; Institute for Pharmaceutical Chemistry, Structural Genomics Consortium, Johann Wolfgang Goethe-University, Max-von-Laue-Strasse 9, Frankfurt am Main, 60438, Germany.; Department of Chemistry, Masaryk University, Brno 625 00, Czech Republic., Remeš M; Department of Chemistry, Masaryk University, Brno 625 00, Czech Republic., Beňovský P; Department of Chemistry, Masaryk University, Brno 625 00, Czech Republic., Böck MC; Department of Chemistry, Masaryk University, Brno 625 00, Czech Republic., Šranková E; Department of Chemistry, Masaryk University, Brno 625 00, Czech Republic., Wong JF; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, U.K., Cros J; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, U.K., Williams E; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, U.K., Tse LH; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, U.K., Smil D; Drug Discovery Program, Ontario Institute for Cancer Research, 661 University Avenue, Toronto, Ontario M5G 0A3, Canada., Ensan D; Drug Discovery Program, Ontario Institute for Cancer Research, 661 University Avenue, Toronto, Ontario M5G 0A3, Canada., Isaac MB; Drug Discovery Program, Ontario Institute for Cancer Research, 661 University Avenue, Toronto, Ontario M5G 0A3, Canada., Al-Awar R; Drug Discovery Program, Ontario Institute for Cancer Research, 661 University Avenue, Toronto, Ontario M5G 0A3, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario M5S 1A8, Canada., Gomolková R; Department of Biology, Faculty of Medicine, Masaryk University, 625 00 Brno, Czech Republic.; Institute of Animal Physiology and Genetics of the Czech Academy of Sciences, 602 00 Brno, Czech Republic., Ursachi VC; Department of Biology, Faculty of Medicine, Masaryk University, 625 00 Brno, Czech Republic.; International Clinical Research Center, St. Anne's University Hospital, 602 00 Brno, Czech Republic., Fafílek B; Department of Biology, Faculty of Medicine, Masaryk University, 625 00 Brno, Czech Republic.; Institute of Animal Physiology and Genetics of the Czech Academy of Sciences, 602 00 Brno, Czech Republic.; International Clinical Research Center, St. Anne's University Hospital, 602 00 Brno, Czech Republic., Kahounová Z; Institute of Biophysics of the Czech Academy of Sciences, Královopolská 135, 612 00 Brno Czech Republic., Víchová R; Institute of Biophysics of the Czech Academy of Sciences, Královopolská 135, 612 00 Brno Czech Republic., Vacek O; International Clinical Research Center, St. Anne's University Hospital, 602 00 Brno, Czech Republic.; Institute of Biophysics of the Czech Academy of Sciences, Královopolská 135, 612 00 Brno Czech Republic., Berger BT; Institute for Pharmaceutical Chemistry, Structural Genomics Consortium, Johann Wolfgang Goethe-University, Max-von-Laue-Strasse 9, Frankfurt am Main, 60438, Germany., Wells CI; Structural Genomics Consortium, UNC Eshelman School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States., Corona CR; Promega Corporation, Madison, Wisconsin 53716, United States., Vasta JD; Promega Corporation, Madison, Wisconsin 53716, United States., Robers MB; Promega Corporation, Madison, Wisconsin 53716, United States., Krejci P; Department of Biology, Faculty of Medicine, Masaryk University, 625 00 Brno, Czech Republic.; Institute of Animal Physiology and Genetics of the Czech Academy of Sciences, 602 00 Brno, Czech Republic.; International Clinical Research Center, St. Anne's University Hospital, 602 00 Brno, Czech Republic., Souček K; International Clinical Research Center, St. Anne's University Hospital, 602 00 Brno, Czech Republic.; Institute of Biophysics of the Czech Academy of Sciences, Královopolská 135, 612 00 Brno Czech Republic., Bullock AN; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, U.K., Knapp S; Institute for Pharmaceutical Chemistry, Structural Genomics Consortium, Johann Wolfgang Goethe-University, Max-von-Laue-Strasse 9, Frankfurt am Main, 60438, Germany., Paruch K; Department of Chemistry, Masaryk University, Brno 625 00, Czech Republic.; Institute of Animal Physiology and Genetics of the Czech Academy of Sciences, 602 00 Brno, Czech Republic.

المصدر: Journal of medicinal chemistry [J Med Chem] 2024 Aug 08; Vol. 67 (15), pp. 12632-12659. Date of Electronic Publication: 2024 Jul 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Activin Receptors, Type II*/metabolism , Activin Receptors, Type II*/antagonists & inhibitors, Animals ; Humans ; Mice ; Activin Receptors, Type I/antagonists & inhibitors ; Activin Receptors, Type I/metabolism ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/chemistry ; Structure-Activity Relationship ; Signal Transduction/drug effects ; Drug Discovery ; Molecular Probes/chemistry ; Bone Morphogenetic Proteins/metabolism ; Pyrazoles/chemistry ; Pyrazoles/pharmacology ; Pyrazoles/chemical synthesis

المؤلفون: Dopfer J; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Max-von-Laue-Str. 9, 60438, Frankfurt am Main, Germany.; Structural Genomics Consortium, Goethe University Frankfurt, Buchmann Institute for Life Sciences, Max-von-Laue-Str. 15, 60438, Frankfurt am Main, Germany., Vasta JD; Promega Corporation, Madison, WI, USA., Müller S; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Max-von-Laue-Str. 9, 60438, Frankfurt am Main, Germany.; Structural Genomics Consortium, Goethe University Frankfurt, Buchmann Institute for Life Sciences, Max-von-Laue-Str. 15, 60438, Frankfurt am Main, Germany., Knapp S; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Max-von-Laue-Str. 9, 60438, Frankfurt am Main, Germany.; Structural Genomics Consortium, Goethe University Frankfurt, Buchmann Institute for Life Sciences, Max-von-Laue-Str. 15, 60438, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK)/German Cancer Research Center (DKFZ), DKTK Site Frankfurt-Mainz, 69120, Heidelberg, Germany., Robers MB; Promega Corporation, Madison, WI, USA., Schwalm MP; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Max-von-Laue-Str. 9, 60438, Frankfurt am Main, Germany. schwalm@pharmchem.uni-frankfurt.de.; Structural Genomics Consortium, Goethe University Frankfurt, Buchmann Institute for Life Sciences, Max-von-Laue-Str. 15, 60438, Frankfurt am Main, Germany. schwalm@pharmchem.uni-frankfurt.de.; German Cancer Consortium (DKTK)/German Cancer Research Center (DKFZ), DKTK Site Frankfurt-Mainz, 69120, Heidelberg, Germany. schwalm@pharmchem.uni-frankfurt.de.

المصدر: Nature communications [Nat Commun] 2024 Jul 05; Vol. 15 (1), pp. 5646. Date of Electronic Publication: 2024 Jul 05.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Fluorescence Resonance Energy Transfer*/methods, Crowdsourcing ; Humans ; Fluorescent Dyes/chemistry ; Drug Discovery/methods ; Ligands ; Databases, Factual ; Bioluminescence Resonance Energy Transfer Techniques/methods ; Fluorescence Polarization/methods

المؤلفون: Capener JL; Structural Genomics Consortium, Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Vasta JD; Promega Corporation, 2800 Woods Hollow Road, Madison, WI 53711, USA., Katis VL; ARUK Oxford Drug Discovery Institute, Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, UK., Michaud A; Promega Corporation, 2800 Woods Hollow Road, Madison, WI 53711, USA., Beck MT; Promega Corporation, 2800 Woods Hollow Road, Madison, WI 53711, USA., Daglish SCD; Structural Genomics Consortium, Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Cohen-Kedar S; Division of Gastroenterology, Rabin Medical Center, Petah-Tikva, Israel.; Felsenstein Medical Research Center, Faculty of Medical & Health Sciences, Tel-Aviv University, Tel-Aviv, Israel., Barda ES; Division of Gastroenterology, Rabin Medical Center, Petah-Tikva, Israel.; Felsenstein Medical Research Center, Faculty of Medical & Health Sciences, Tel-Aviv University, Tel-Aviv, Israel., Howell S; Structural Genomics Consortium, Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Dotan I; Division of Gastroenterology, Rabin Medical Center, Petah-Tikva, Israel.; Felsenstein Medical Research Center, Faculty of Medical & Health Sciences, Tel-Aviv University, Tel-Aviv, Israel., Robers MB; Promega Corporation, 2800 Woods Hollow Road, Madison, WI 53711, USA., Axtman AD; Structural Genomics Consortium, Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Bashore FM; Structural Genomics Consortium, Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jun 13. Date of Electronic Publication: 2024 Jun 13.

نوع المنشور: Journal Article; Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Ku AF; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA., Sharma KL; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA., Ta HM; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.; Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX 77030, USA., Sutton CM; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA., Bohren KM; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA., Wang Y; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA., Chamakuri S; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA., Chen R; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA., Hakenjos JM; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA., Jimmidi R; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA., Kent K; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Li F; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.; Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX 77030, USA., Li JY; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA., Ma L; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA., Madasu C; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA., Palaniappan M; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA., Palmer SS; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA., Qin X; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA., Robers MB; Promega Corporation, Madison, WI 53711, USA., Sankaran B; Molecular Biophysics and Integrated Bioimaging, Berkeley Center for Structural Biology, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA., Tan Z; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.; Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX 77030, USA., Vasquez YM; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA., Wang J; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA., Wilkinson J; Promega Corporation, Madison, WI 53711, USA., Yu Z; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA., Ye Q; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA., Young DW; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.; Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX 77030, USA., Teng M; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.; Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX 77030, USA., Kim C; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.; Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX 77030, USA., Matzuk MM; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.; Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.

المصدر: Science (New York, N.Y.) [Science] 2024 May 24; Vol. 384 (6698), pp. 885-890. Date of Electronic Publication: 2024 May 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Contraceptive Agents, Male*/chemistry , Contraceptive Agents, Male*/pharmacology , Protein Kinase Inhibitors*/pharmacology , Protein Kinase Inhibitors*/chemistry , Protein Serine-Threonine Kinases*/antagonists & inhibitors , Protein Serine-Threonine Kinases*/chemistry , Small Molecule Libraries*/chemistry , Small Molecule Libraries*/pharmacology , Contraception*/methods, Animals ; Humans ; Male ; Mice ; Blood-Testis Barrier/metabolism ; Testis/drug effects ; Structure-Activity Relationship

المؤلفون: Sugawara T; Bayer AG, Pharmaceuticals, Research & Early Development Oncology, Berlin, Germany., Nevedomskaya E; Bayer AG, Pharmaceuticals, Research & Early Development Oncology, Berlin, Germany., Heller S; Nuvisan ICB GmbH, Berlin, Germany., Böhme A; Nuvisan ICB GmbH, Berlin, Germany., Lesche R; Nuvisan ICB GmbH, Berlin, Germany., von Ahsen O; Nuvisan ICB GmbH, Berlin, Germany., Grünewald S; Nuvisan ICB GmbH, Berlin, Germany., Nguyen HM; Department of Urology, University of Washington, Seattle, WA, USA., Corey E; Department of Urology, University of Washington, Seattle, WA, USA., Baumgart SJ; Bayer AG, Pharmaceuticals, Research & Early Development Oncology, Berlin, Germany., Georgi V; Bayer AG, Pharmaceuticals, Research & Early Development Oncology, Berlin, Germany., Pütter V; Bayer AG, Pharmaceuticals, Research & Early Development Oncology, Berlin, Germany., Fernández-Montalván A; Bayer AG, Pharmaceuticals, Research & Early Development Oncology, Berlin, Germany., Vasta JD; Promega Corporation, Madison, WI, USA., Robers MB; Promega Corporation, Madison, WI, USA., Politz O; Bayer AG, Pharmaceuticals, Research & Early Development Oncology, Berlin, Germany., Mumberg D; Bayer AG, Pharmaceuticals, Research & Early Development Oncology, Berlin, Germany., Haendler B; Bayer AG, Pharmaceuticals, Research & Early Development Oncology, Berlin, Germany.

المصدر: Molecular oncology [Mol Oncol] 2024 Mar; Vol. 18 (3), pp. 726-742. Date of Electronic Publication: 2024 Jan 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101308230 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0261 (Electronic) Linking ISSN: 15747891 NLM ISO Abbreviation: Mol Oncol Subsets: MEDLINE

مواضيع طبية MeSH: Proto-Oncogene Proteins c-akt*/metabolism , Prostatic Neoplasms*/genetics, Male ; Humans ; Aged ; Receptors, Androgen/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Caspase 3 ; Androgens ; TOR Serine-Threonine Kinases/metabolism ; Cell Proliferation ; Apoptosis ; Cell Line, Tumor

المؤلفون: Teske KA; Promega Corporation, Research & Development, Madison, WI 53711, USA., Corona C; Promega Corporation, Research & Development, San Luis Obispo, CA 93401, USA., Wilkinson J; Promega Corporation, Research & Development, Madison, WI 53711, USA., Mamott D; Promega Corporation, Research & Development, Madison, WI 53711, USA., Good DA; Promega Corporation, Research & Development, San Luis Obispo, CA 93401, USA., Zambrano D; Promega Corporation, Research & Development, San Luis Obispo, CA 93401, USA., Lazar DF; Promega Corporation, Research & Development, Madison, WI 53711, USA., Cali JJ; Promega Corporation, Research & Development, Madison, WI 53711, USA., Robers MB; Promega Corporation, Research & Development, Madison, WI 53711, USA. Electronic address: matt.robers@promega.com., O'Brien MA; Promega Corporation, Research & Development, Madison, WI 53711, USA. Electronic address: martha.obrien@promega.com.

المصدر: Cell chemical biology [Cell Chem Biol] 2024 Feb 15; Vol. 31 (2), pp. 349-360.e6. Date of Electronic Publication: 2023 Oct 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2451-9448 (Electronic) Linking ISSN: 24519448 NLM ISO Abbreviation: Cell Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Inflammasomes*/metabolism , NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism, Humans ; Cytokines/metabolism ; Interleukin-1beta/metabolism

المؤلفون: Vasta JD; Promega Corporation, Madison, WI, USA., Michaud A; Promega Corporation, Madison, WI, USA., Aaron Crapster J; Vibliome Therapeutics LLC, Bozeman, MT, USA., Robers MB; Promega Corporation, Madison, WI, USA. Matt.Robers@promega.com.

المصدر: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2024; Vol. 2797, pp. 287-297.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029 (Electronic) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE

مواضيع طبية MeSH: Proto-Oncogene Proteins c-raf*/metabolism , Mitogen-Activated Protein Kinases*/metabolism, Humans ; Protein Subunits ; Signal Transduction

المؤلفون: Vasta JD; Promega Corporation, Madison, WI, USA., Michaud A; Promega Corporation, Madison, WI, USA., Zimprich CA; Promega Corporation, Madison, WI, USA., Beck MT; Promega Corporation, Madison, WI, USA., Swiatnicki MR; Promega Corporation, Madison, WI, USA., Zegzouti H; Promega Corporation, Madison, WI, USA., Thomas MR; Promega Corporation, Madison, WI, USA., Wilkinson J; Promega Corporation, Madison, WI, USA., Crapster JA; Vibliome Therapeutics LLC, Bozeman, MT, USA. Electronic address: aaron.crapster@vibliome.com., Robers MB; Promega Corporation, Madison, WI, USA. Electronic address: matt.robers@promega.com.

المصدر: Cell chemical biology [Cell Chem Biol] 2023 Nov 16; Vol. 30 (11), pp. 1354-1365.e6. Date of Electronic Publication: 2023 Aug 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2451-9448 (Electronic) Linking ISSN: 24519448 NLM ISO Abbreviation: Cell Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Proto-Oncogene Proteins B-raf*/genetics , Proto-Oncogene Proteins B-raf*/metabolism , Signal Transduction*, Humans ; Protein Subunits/metabolism ; Cell Line, Tumor ; Protein Kinase Inhibitors/pharmacology ; Mutation ; MAP Kinase Signaling System