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المؤلفون: Richard E. Showalter, Jim Thomson, Yudou He, Mario Meng-Chiang Kuo, Richard Hickey, Wei-Jong Shia, Li-Chang Chen, Elena Brin, Eleanor Dagostino, Katherine Wu, Robert Almassy, Mariusz Stempniak
المصدر: Oncotarget
مصطلحات موضوعية: 0301 basic medicine, Chemistry, apoptosis, Cancer, TRAIL, medicine.disease, Fusion protein, arginine deiminase, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Oncology, Apoptosis, anti-cancer biologic, 030220 oncology & carcinogenesis, Cancer cell, Survivin, medicine, Cancer research, fusion protein, Tumor necrosis factor alpha, Receptor, Arginine deiminase, Research Paper
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::920a1fcfc2cf7ef29450ed87d9dde742
http://europepmc.org/articles/PMC6319333 -
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المؤلفون: Robert Almassy, Theodore J. Boritzki, Karen A. Maegley, Bernard T. Golding, Suzanne Kyle, Huw D. Thomas, Stephen E. Webber, Tikhe Jayashree Girish, A. Hilary Calvert, Nicola J. Curtin, Xiao-Hong Yu, Jianke Li, Zdenek Hostomsky, Roger John Griffin, David Richard Newell, Anne Ekkers, Cathy Zhang, Robert Arnold Kumpf, Christopher R. Calabrese, Lan-Zhen Wang
المصدر: Journal of Medicinal Chemistry. 47:5467-5481
مصطلحات موضوعية: Models, Molecular, Indoles, Molecular model, Stereochemistry, Pyrrolobenzodiazepine, Antineoplastic Agents, Poly(ADP-ribose) Polymerase Inhibitors, Crystallography, X-Ray, Chemical synthesis, Structure-Activity Relationship, chemistry.chemical_compound, Cell Line, Tumor, Drug Discovery, Humans, Structure–activity relationship, Binding site, Benzamide, Cell Proliferation, biology, Chemistry, NAD+ ADP-Ribosyltransferase, Active site, Drug Synergism, Azepines, Drug Resistance, Neoplasm, Drug Design, biology.protein, Molecular Medicine, Topoisomerase I Inhibitors
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المؤلفون: Victor I. Nikulin, Sam Chu, Martina E. Tedder, Kelly Sprankle, Kraig M. Yager, Mitra Khalili, Krzysztof Appelt, Li Xiaoming, James Levin, Victoria A. Feher, Stephen Margosiak, Robert Almassy, Zhe Nie
المصدر: Journal of Medicinal Chemistry. 46:5663-5673
مصطلحات موضوعية: Models, Molecular, Indazoles, Streptococcus pyogenes, Microbial Sensitivity Tests, Neisseria meningitidis, Crystallography, X-Ray, Chemical synthesis, Structure-Activity Relationship, chemistry.chemical_compound, Methylthioadenosine nucleosidase, Drug Discovery, N-Glycosyl Hydrolases, Antibacterial agent, Sulfonamides, Indazole, Binding Sites, biology, Chemistry, Biological activity, Antimicrobial, Anti-Bacterial Agents, Adenosylhomocysteine nucleosidase, Streptococcus pneumoniae, Biochemistry, Enzyme inhibitor, Drug Design, biology.protein, Molecular Medicine
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المؤلفون: Marakovits Joseph T, David R. Newell, Stephen E. Webber, Zdenek Hostomsky, Roger J. Griffin, Karen A. Maegley, Anne Ekker, Skalitzky Donald James, Bernard T. Golding, Robert Almassy, A. Hilary Calvert, Xiao-Hong Yu, Jianke Li, Eastman Brian Walter, Nicola J. Curtin
المصدر: Journal of Medicinal Chemistry. 46:210-213
مصطلحات موضوعية: Models, Molecular, Benzimidazole, medicine.drug_class, Stereochemistry, DNA damage, Poly ADP ribose polymerase, Antineoplastic Agents, Carboxamide, Poly(ADP-ribose) Polymerase Inhibitors, Crystallography, X-Ray, Poly (ADP-Ribose) Polymerase Inhibitor, Cell Line, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Temozolomide, medicine, Humans, Chemosensitizing agent, Prodrugs, Enzyme Inhibitors, Binding Sites, NAD+ ADP-Ribosyltransferase, Stereoisomerism, Dacarbazine, chemistry, Biochemistry, Drug Resistance, Neoplasm, Molecular Medicine, Benzimidazoles, NAD+ kinase, Topotecan, Heterocyclic Compounds, 3-Ring
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المؤلفون: Huw D. Thomas, Anne Ekker, Stephen E. Webber, Christopher R. Calabrese, Nicola J. Curtin, Robert Almassy, Karen A. Maegley, Rena N. Mansour, Lan-Zhen Wang, Robert Arnold Kumpf, A. Hilary Calvert, Cathy Zhang, Scott E. Zook, Jianke Li, Bernard T. Golding, Tikhe Jayashree Girish, Xiao-Hong Yu, Suzanne Kyle, Zdenek Hostomsky, Theodore J. Boritzki, Thoresen Lars Henrik, David Richard Newell, Kanyin E. Zhang, Stacie S. Canan Koch, Roger John Griffin
المصدر: Journal of Medicinal Chemistry. 45:4961-4974
مصطلحات موضوعية: Indoles, Stereochemistry, Poly ADP ribose polymerase, Antineoplastic Agents, Poly(ADP-ribose) Polymerase Inhibitors, Crystallography, X-Ray, Chemical synthesis, Cocrystal, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Temozolomide, Tumor Cells, Cultured, Humans, Enzyme Inhibitors, Benzamide, chemistry.chemical_classification, biology, Chemistry, NAD+ ADP-Ribosyltransferase, Drug Synergism, Isoquinolines, NAD, In vitro, Dacarbazine, Enzyme, Enzyme inhibitor, Drug Design, biology.protein, Molecular Medicine, Drug Screening Assays, Antitumor, Poly(ADP-ribose) Polymerases, Topotecan
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المؤلفون: S Srinivasan, Bernard T. Golding, Alex William White, Karen A. Maegley, David R. Newell, Roger J. Griffin, A. Hilary Calvert, Robert Almassy, Nicola J. Curtin, Zdenek Hostomsky
المصدر: Journal of Medicinal Chemistry. 43:4084-4097
مصطلحات موضوعية: Models, Molecular, DNA repair, Poly ADP ribose polymerase, Antineoplastic Agents, Poly(ADP-ribose) Polymerase Inhibitors, Crystallography, X-Ray, Poly (ADP-Ribose) Polymerase Inhibitor, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Temozolomide, Tumor Cells, Cultured, Humans, Enzyme Inhibitors, Cytotoxicity, Polymerase, biology, Drug Synergism, Dacarbazine, Biochemistry, chemistry, Drug Resistance, Neoplasm, Enzyme inhibitor, biology.protein, Molecular Medicine, Benzimidazoles, Drug Screening Assays, Antitumor, Topotecan, DNA, Nucleotide excision repair
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المؤلفون: R. Ferre, Varney Michael D, William H. Romines, Theodore Boritzki, Eleanor J. Howland, Cheryl Ann Janson, Stephen Margosiak, Cindy L. Palmer, Robert Almassy, Charlotte A. Bartlett
المصدر: Journal of Medicinal Chemistry. 40:2502-2524
مصطلحات موضوعية: Hydroxymethyl and Formyl Transferases, Models, Molecular, Phosphoribosylglycinamide formyltransferase, Protein Conformation, Stereochemistry, Substituent, Antineoplastic Agents, Stereoisomerism, Crystallography, X-Ray, Chemical synthesis, Phosphoribosylaminoimidazolecarboxamide Formyltransferase, Mice, chemistry.chemical_compound, Folic Acid, Drug Discovery, Escherichia coli, Tumor Cells, Cultured, Animals, Humans, Moiety, Phosphoribosylglycinamide Formyltransferase, Phosphoribosylaminoimidazolecarboxamide formyltransferase, Bicyclic molecule, Chemistry, Recombinant Proteins, Pyrimidines, Drug Design, Molecular Medicine, Aliphatic compound, Acyltransferases, Cell Division
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المؤلفون: Cindy L. Palmer, Robert Almassy, R. Ferre, Theodore Boritzki, Charlotte A. Bartlett, Stephen Margosiak, Varney Michael D, Eleanor J. Howland, Cheryl Ann Janson, William H. Romines
المصدر: ChemInform. 28
مصطلحات موضوعية: chemistry.chemical_classification, chemistry.chemical_compound, Protein structure, Bicyclic molecule, Chemistry, Stereochemistry, Cell growth, Thiophene, Substituent, Thiol, Moiety, General Medicine, Alkyl
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المؤلفون: Eunice Li, Scott A. Mitchell, Kevin Farley, Thomas H. Chyba, Steven Simpson, Ryan Da Re, Jay Pendell-Jones, Darren K. Emge, Robert Almassy, Timothy Reed, Ahmed Slamani, Christin Gunning, David Baughman, Mohamed-Adel Slamani, Amber Polizzi, Steven Andrew MacDonald, Brian Fisk
المصدر: SPIE Proceedings.
مصطلحات موضوعية: Taguchi methods, Chemical Warfare Agents, symbols.namesake, Computer science, Detector, System identification, Benchmark (computing), symbols, Figure of merit, Raman spectroscopy, Algorithm, Test data
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::48f6ffa2738ff44c5c758aa537886bf5
https://doi.org/10.1117/12.850529 -
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المؤلفون: Carin L. Perretta, April Averill, Shaosong Chu, Robert Almassy, Stephen Margosiak, Jia Lu, Zhe Nie, Erickson Philip Eugene
المصدر: Bioorganicmedicinal chemistry letters. 18(2)
مصطلحات موضوعية: Male, Molecular model, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Molecular Conformation, Pharmaceutical Science, Carboxamide, Antineoplastic Agents, Crystallography, X-Ray, Biochemistry, Chemical synthesis, chemistry.chemical_compound, Structure-Activity Relationship, 1,3,5-Triazine, Cell Line, Tumor, Drug Discovery, medicine, Structure–activity relationship, Animals, Humans, Casein Kinase II, Molecular Biology, Protein Kinase Inhibitors, Triazine, biology, Triazines, Organic Chemistry, Prostatic Neoplasms, chemistry, Enzyme inhibitor, Drug Design, Colonic Neoplasms, biology.protein, Lactam, Molecular Medicine
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