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1
المؤلفون: Martin Saunders, Robert William Ward, Ashley E. Fenwick, Brian Peter Slingsby, Rachel Stacey, Robert John Ife, David Smith, David Haigh, Marianne Buffet
المصدر: Bioorganic & Medicinal Chemistry Letters. 11:635-639
مصطلحات موضوعية: Bipolar Disorder, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Chemical synthesis, Maleimides, Structure-Activity Relationship, GSK-3, Drug Discovery, Animals, Humans, Enzyme Inhibitors, Glycogen synthase, Protein kinase A, Molecular Biology, chemistry.chemical_classification, Molecular Structure, biology, Kinase, Organic Chemistry, Glycogen Synthase Kinases, In vitro, Enzyme, chemistry, Enzyme inhibitor, Calcium-Calmodulin-Dependent Protein Kinases, biology.protein, Molecular Medicine
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2
المؤلفون: Ashley E. Fenwick, Andrew Derrick Gribble, Nichola Stevens, Jason Witherington, Robert John Ife
المصدر: Bioorganic & Medicinal Chemistry Letters. 11:199-202
مصطلحات موضوعية: Ketone, Stereochemistry, Cathepsin K, Clinical Biochemistry, Pharmaceutical Science, Buffers, Cysteine Proteinase Inhibitors, Biochemistry, Chemical synthesis, Structure-Activity Relationship, chemistry.chemical_compound, Heterocyclic Compounds, Drug Discovery, Combinatorial Chemistry Techniques, Humans, Enzyme Inhibitors, Furans, Molecular Biology, chemistry.chemical_classification, biology, Organic Chemistry, Diastereomer, Benzothiophene, Biological activity, Ketones, Cathepsins, Kinetics, Enzyme, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine
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3
المؤلفون: Deirdre M. B. Hickey, Ian Stansfield, Leach Colin Andrew, Caroline M. Whittaker, Ivan Leo Pinto, Stephen A. Smith, Stephen Christopher Martin Fell, Sean Thomas Flynn, Kitty Moores, Helen F. Boyd, Colin J. Theobald, David G. Tew, Roderick A. Porter, Robert John Ife, Kevin J. Milliner, Colin H. Macphee, D. Anthony Rawlings
المصدر: Bioorganic & Medicinal Chemistry Letters. 10:2557-2561
مصطلحات موضوعية: medicine.drug_class, Stereochemistry, Lipoproteins, Clinical Biochemistry, Administration, Oral, Pharmaceutical Science, Carboxamide, Pyrimidinones, Biochemistry, Chemical synthesis, Phospholipases A, chemistry.chemical_compound, Phospholipase A2, Oral administration, Drug Discovery, medicine, Animals, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, Molecular Structure, biology, Chemistry, Lipoprotein-associated phospholipase A2, Organic Chemistry, Phospholipases A2, Enzyme, Enzyme inhibitor, biology.protein, Lactam, Molecular Medicine, Rabbits
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4
المؤلفون: Martin Jones, Colin J. Theobald, Leach Colin Andrew, Sean Thomas Flynn, Deirdre M. B. Hickey, Ian Stansfield, David G. Tew, Brian Peter Slingsby, Helen F. Boyd, Stephen A. Smith, Kevin J. Milliner, Colin H. Macphee, Robert John Ife, D. Anthony Rawlings
المصدر: Bioorganic & Medicinal Chemistry Letters. 10:395-398
مصطلحات موضوعية: Stereochemistry, High-throughput screening, Clinical Biochemistry, Drug Evaluation, Preclinical, Pharmaceutical Science, Pyrimidinones, Biochemistry, Chemical synthesis, Phospholipases A, Substrate Specificity, Inhibitory Concentration 50, Structure-Activity Relationship, Phospholipase A2, Drug Discovery, Humans, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, biology, Chemistry, Lipoprotein-associated phospholipase A2, Organic Chemistry, Substrate (chemistry), Phospholipases A2, Enzyme, Enzyme inhibitor, Drug Design, 1-Alkyl-2-acetylglycerophosphocholine Esterase, biology.protein, Molecular Medicine, Selectivity
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5
المؤلفون: Rachel Stacey, Peter Skett, Patrick Lavery, David Haigh, Brian Peter Slingsby, Robert John Ife, David Smith, Andrew West, Andrew Derrick Gribble, Robert William Ward
المصدر: Bioorganic & Medicinal Chemistry Letters. 9:3137-3142
مصطلحات موضوعية: Human cytomegalovirus, Serine Proteinase Inhibitors, Stereochemistry, Molecular Sequence Data, Clinical Biochemistry, Cytomegalovirus, Pharmaceutical Science, Hydroxylamines, Biochemistry, Chemical synthesis, Mass Spectrometry, Acylation, chemistry.chemical_compound, Anti-Infective Agents, Drug Discovery, medicine, Humans, Trypsin, Amino Acid Sequence, Molecular Biology, chemistry.chemical_classification, Binding Sites, Molecular Structure, biology, Aryl, Serine Endopeptidases, Organic Chemistry, Biological activity, medicine.disease, Peptide Fragments, In vitro, Enzyme, chemistry, Enzyme inhibitor, Cytomegalovirus Infections, biology.protein, Molecular Medicine
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6
المؤلفون: Helen F. Boyd, Deirdre M. B. Hickey, Kitty Moores, Kevin J. Milliner, Colin H. Macphee, Dash Dhanak, Keith E. Suckling, Leach Colin Andrew, Rebecca A. Patterson, Robert John Ife, David S. Leake, David G. Tew
المصدر: Biochemical Journal. 338:479-487
مصطلحات موضوعية: chemistry.chemical_classification, biology, Lipoprotein-associated phospholipase A2, Fatty acid, Cell Biology, 1-Alkyl-2-acetylglycerophosphocholine Esterase, Biochemistry, chemistry.chemical_compound, Phospholipase A2, Lysophosphatidylcholine, chemistry, Low-density lipoprotein, biology.protein, lipids (amino acids, peptides, and proteins), Chemoattractant activity, Molecular Biology, Lipoprotein
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fbda5ac7d34f8ba6f99f2e2fc0fda486
https://doi.org/10.1042/bj3380479 -
7
المؤلفون: Leach Colin Andrew, Robert John Ife, A.J. Pope, C.J. Theobald
المصدر: Bioorganic & Medicinal Chemistry Letters. 5:543-546
مصطلحات موضوعية: Bicyclic molecule, biology, Stereochemistry, ATPase, Organic Chemistry, Clinical Biochemistry, Quinoline, Gastric H+/K+ ATPase, Pharmaceutical Science, Protonation, Biochemistry, chemistry.chemical_compound, chemistry, Drug Discovery, Pyridine, biology.protein, Molecular Medicine, Molecule, Thiazole, Molecular Biology
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8
المؤلفون: David J. Keeling, M. E. Parsons, Robert John Ife, S. M. Laing, C. A. Price, K. J. Wiggall, Leach Colin Andrew, T. H. Brown
المصدر: ChemInform. 24
مصطلحات موضوعية: chemistry.chemical_compound, Chemistry, Stereochemistry, Gastric H+/K+ ATPase, Substituent, General Medicine
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9
المؤلفون: Leach Colin Andrew, David G. Tew, Deirdre M. B. Hickey, Stephen A. Smith, Robert John Ife, Colin H. Macphee
المصدر: ChemInform. 32
مصطلحات موضوعية: chemistry.chemical_classification, biology, Monocyte, General Medicine, Pharmacology, Proinflammatory cytokine, chemistry.chemical_compound, Enzyme, medicine.anatomical_structure, Phospholipase A2, chemistry, Low-density lipoprotein, Phosphatidylcholine, biology.protein, medicine, lipids (amino acids, peptides, and proteins), Lipase, Lipoprotein
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10
المؤلفون: Leach Colin Andrew, David R. Reavill, Kenneth Wiggall, Colin J. Theobald, David J. Keeling, Robert John Ife, Thomas Henry Brown, Malcolm L. Meeson, Michael E. Parsons
المصدر: Journal of Medicinal Chemistry. 35:3413-3422
مصطلحات موضوعية: Stereochemistry, Substituent, Gastric Acid, H(+)-K(+)-Exchanging ATPase, Structure-Activity Relationship, chemistry.chemical_compound, Dogs, In vivo, Drug Discovery, Animals, Enzyme Inhibitors, Adenosine Triphosphatases, chemistry.chemical_classification, biology, Bicyclic molecule, Hydrogen bond, Quinoline, Rats, Enzyme, chemistry, Gastric Mucosa, Enzyme inhibitor, Quinolines, biology.protein, Molecular Medicine, Gastric acid