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المؤلفون: Douglas G. Johns, Louis-Charles Campeau, Puja Banka, An Bautmans, Tjerk Bueters, Elisabetta Bianchi, Danila Branca, Paul G. Bulger, Inne Crevecoeur, Fa-Xiang Ding, Robert M. Garbaccio, Erik D. Guetschow, Yan Guo, Sookhee N. Ha, Jennifer M. Johnston, Hubert Josien, Eunkyung A. Kauh, Kenneth A. Koeplinger, Jeffrey T. Kuethe, Eseng Lai, Christine L. Lanning, Anita Y.H. Lee, Li Li, Anilkumar G. Nair, Edward A. O’Neill, S. Aubrey Stoch, David A. Thaisrivongs, Thomas J. Tucker, Petr Vachal, Kristien van Dyck, Frederic P. Vanhoutte, Bram Volckaert, Dennis G. Wolford, Andy Xu, Tian Zhao, Dan Zhou, Susan Zhou, Xiaohong Zhu, Hratch J. Zokian, Abbas Walji, Harold B. Wood
المصدر: Circulation.
مصطلحات موضوعية: Physiology (medical), Cardiology and Cardiovascular Medicine
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6f19bd0c61c330917293f0ae4cf3d908
https://doi.org/10.1161/circulationaha.122.063372 -
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المؤلفون: Dmitri A. Pissarnitski, Ahmet Kekec, Lin Yan, Yuping Zhu, Danqing D. Feng, Pei Huo, Christina Madsen-Duggan, Christopher R. Moyes, Ravi P. Nargund, Terri Kelly, Xiaoping Zhang, Ester Carballo-Jane, Judith Gorski, Peter Zafian, Mo Qatanani, Niels Kaarsholm, Fanyu Meng, Xiujuan Jia, Keun-Joong Lee, Weixun Wang, Sherrie Xu, Michael J. Hohn, Michael J. Iammarino, Mark A. McCoy, Grace A. Okoh, Yingkai Liang, Scott A. Hollingsworth, Mark D. Erion, David E. Kelley, Robert M. Garbaccio, Amy Zhang, James Mu, Songnian Lin
المصدر: Journal of Medicinal Chemistry. 65:5593-5605
مصطلحات موضوعية: Blood Glucose, Dogs, Therapeutic Index, Diabetes Mellitus, Type 2, Swine, Drug Discovery, Animals, Hypoglycemic Agents, Insulin, Swine, Miniature, Molecular Medicine, Hypoglycemia, Receptor, Insulin
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المؤلفون: Federica Orvieto, Mark J Demma, Canada Keith A, Alycia V Shoultz, Alessia Santoprete, Kuanchang Chen, Amy Bittner Mccracken, Xiaohong Zhu, Scott A. Johnson, Claudio Mapelli, Iman Farasat, Brian M. Lacey, Zachary Z Brown, Abbas Walji, Robert M. Garbaccio, Jennifer O'Neil, Elisabetta Bianchi
المصدر: The Journal of organic chemistry. 85(3)
مصطلحات موضوعية: chemistry.chemical_classification, Coiled coil, 010405 organic chemistry, Organic Chemistry, Mutagenesis, Cell, Peptide, DNA, 010402 general chemistry, Native chemical ligation, 01 natural sciences, Peptide Fragments, 0104 chemical sciences, Amino acid, Cell biology, Cell Line, Proto-Oncogene Proteins c-myc, chemistry.chemical_compound, medicine.anatomical_structure, chemistry, medicine, Peptide synthesis, Protein Binding
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المؤلفون: Spencer D. Dreher, Nicholas K. Terrett, Emma R. Parmee, Matthew D. Truppo, Richard D. Tillyer, Robert M. Garbaccio, Kevin R. Campos, Juan C. Alvarez, Paul J. Coleman
المصدر: Science (New York, N.Y.). 363(6424)
مصطلحات موضوعية: Drug Industry, Emerging technologies, Photochemistry, Chemistry, Pharmaceutical, Mature technology, 010402 general chemistry, Chemist, 01 natural sciences, Machine Learning, Inventions, Drug Discovery, Pharmaceutical industry, Multidisciplinary, 010405 organic chemistry, Drug discovery, business.industry, Biosynthetic Chemistry, Chemical space, 0104 chemical sciences, Enzymes, High-Throughput Screening Assays, Pharmaceutical Preparations, Cheminformatics, Biocatalysis, Biochemical engineering, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4944906dcdf6c76e77faf1e97bcee336
https://pubmed.ncbi.nlm.nih.gov/30655413 -
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المؤلفون: Michael J. Kelly, Marlene A. Jacobson, Kerry L. Fillgrove, Alexander J. Reif, Ken Arrington, Robert M. Garbaccio, Kevin J. Rodzinak, Cheng Wang, Timothy J. Hartingh, Brian C. Magliaro, Sarah L. Huszar, Yuhsin Kuo, Cuyue Tang, Jason M. Uslaner, Vadim Y. Dudkin, Julie A. O'Brien, Mark E. Layton
المصدر: Bioorganic & Medicinal Chemistry Letters. 26:1260-1264
مصطلحات موضوعية: 0301 basic medicine, Pyridines, Pyridones, Clinical Biochemistry, Allosteric regulation, Drug Evaluation, Preclinical, Pharmaceutical Science, Pharmacology, Receptors, Metabotropic Glutamate, Biochemistry, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Allosteric Regulation, Drug Discovery, Animals, Potency, Structure–activity relationship, Receptor, Molecular Biology, Chemistry, Organic Chemistry, Imidazoles, Glutamate receptor, Rats, Disease Models, Animal, 030104 developmental biology, Metabotropic receptor, Psychotic Disorders, Metabotropic glutamate receptor, Molecular Medicine, Metabotropic glutamate receptor 2, Locomotion, 030217 neurology & neurosurgery, Protein Binding
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المؤلفون: Edward C. Sherer, Hannah D. G. F. Lehman, Kerry L. Fillgrove, Robert M. Garbaccio, Jason M. Uslaner, Brian C. Magliaro, Marlene A. Jacobson, Cuyue Tang, Yuhsin Kuo, Rossi Michael A, Michael J. Kelly, Joseph E. Pero, Julie A. O'Brien, Leo A. Joyce, Mark E. Layton, Sarah L. Huszar
المصدر: ACS Medicinal Chemistry Letters. 7:312-317
مصطلحات موضوعية: 0301 basic medicine, Ligand efficiency, Stereochemistry, Organic Chemistry, Allosteric regulation, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, chemistry, Pharmacokinetics, In vivo, Metabotropic glutamate receptor, Amide, Drug Discovery, Amine gas treating, Metabotropic glutamate receptor 2, 030217 neurology & neurosurgery
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المؤلفون: Emma R. Parmee, Robert M. Garbaccio
المصدر: Cell Chemical Biology. 23(1):10-17
مصطلحات موضوعية: 0301 basic medicine, Pharmaceutical drug, Dipeptidyl Peptidase 4, medicine.medical_treatment, Clinical Biochemistry, Chemical probe, Nanotechnology, Scientific field, Protein Serine-Threonine Kinases, Biology, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Biochemistry, Receptor, Cannabinoid, CB2, Small Molecule Libraries, 03 medical and health sciences, Preclinical research, Drug Discovery, medicine, Animals, Humans, HIV Integrase Inhibitors, Molecular Targeted Therapy, Molecular Biology, Pharmaceutical industry, Pharmacology, Dipeptidyl-Peptidase IV Inhibitors, Potential impact, Drug discovery, business.industry, Perspective (graphical), Proteins, 030104 developmental biology, Risk analysis (engineering), Protein Biosynthesis, Molecular Medicine, business, Proto-Oncogene Proteins c-akt
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea4071ce6fc81782b64775719f06642c
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المؤلفون: Rong Xiang, Tao Pei, Stephanie E. Barrett, J. Michael Williams, Robert M. Garbaccio, Erin N. Guidry, Jing Liao
المصدر: Journal of Polymer Science Part A: Polymer Chemistry. 54:311-315
مصطلحات موضوعية: chemistry.chemical_classification, Polymers and Plastics, Organic Chemistry, 02 engineering and technology, Ornithine, 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, Ring-opening polymerization, 0104 chemical sciences, Amino acid, chemistry.chemical_compound, chemistry, Drug delivery, Polymer chemistry, Materials Chemistry, Organic chemistry, 0210 nano-technology
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المؤلفون: Juhi Firdos, Kern Jeffrey, Dennis M. Zaller, Douglas Hodges, Laurence Fayadat-Dilman, Isabel Figueroa, Shuli Zhang, Anthony Manibusan, Peter Stivers, Lily Y. Moy, Hyun Chong Woo, Yiwei Zhang, Nickolas Knudsen, Philip E. Brandish, Laura Garvin-Queen, Svetlana Antonenko, Kristen Kwasnjuk, Daniela M. Tomazela, Prasanthi Geda, SuChun Hseih, Mark T. Cancilla, Sanjiv J. Shah, Robert M. Garbaccio, Maribel Beaumont, John H. Shin, Lia Benso, Dennis Gately, Huiping Ma, Christopher Haines, Mangeng Cheng, Paul L. Miller, Mark Zielstorff, Linda Liang, Anthony Palmieri, Ying Sun, Guo Feng, Yujie Qu
المصدر: Bioconjugate chemistry. 29(7)
مصطلحات موضوعية: 0301 basic medicine, Immunoconjugates, Biomedical Engineering, Anti-Inflammatory Agents, Pharmaceutical Science, Bioengineering, Mice, Transgenic, Pharmacology, 03 medical and health sciences, Mice, 0302 clinical medicine, Immune system, Glucocorticoid receptor, Drug Delivery Systems, Receptors, Glucocorticoid, Antigen, Drug Development, Drug Stability, In vivo, medicine, Animals, Humans, Receptor, Glucocorticoids, B-Lymphocytes, biology, Chemistry, Organic Chemistry, Histocompatibility Antigens Class II, Antibodies, Monoclonal, In vitro, Antigens, Differentiation, B-Lymphocyte, 030104 developmental biology, Mechanism of action, 030220 oncology & carcinogenesis, biology.protein, Fluticasone, medicine.symptom, Antibody, Biotechnology
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المؤلفون: Quang Truong, Conrad E. Raab, Michael J. Lyman, Andrew H. Latham, Haihong Fan, Eileen S. Walsh, Marissa Vavrek, Robert M. Garbaccio, Eric Kemp, Marc Abrams, Erin N. Guidry, Tao Pei, Steven L. Colletti, Laura Sepp-Lorenzino, Edward J. Carlini, Carol Bason, Melissa Stern, J. Michael Williams, Eric D. Soli, Rob S. Burke, Mihir Patel, Jun H. Heo, Brian A. Carr, Stephanie Young, Jacob H. Waldman, Sean Riley, Nicole T. Pudvah, Louis S. Crocker, Bonnie J. Howell, Sergey Pechenov, Steven J. Staskiewicz, Sheri Smith, Marina Busuek, Rubina G. Parmar, Stephanie E. Barrett, Anthony Leone, Robert A. Kowtoniuk
المصدر: Journal of Controlled Release. 183:124-137
مصطلحات موضوعية: Biodistribution, Pharmaceutical Science, Biocompatible Materials, Nanotechnology, Gene delivery, Rats, Sprague-Dawley, Structure-Activity Relationship, Drug Stability, Species Specificity, In vivo, Animals, Humans, Structure–activity relationship, Tissue Distribution, RNA, Small Interfering, Radionuclide Imaging, chemistry.chemical_classification, Drug Carriers, Gene knockdown, Chemistry, Hep G2 Cells, Polymer, Macaca mulatta, Nylons, Liver, Drug Design, Hepatocytes, Biophysics, Autoradiography, Female, Peptides, Drug carrier, Conjugate
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