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1دورية أكاديمية
المؤلفون: David A. Sykes, Mireia Jiménez‐Rosés, John Reilly, Robin A. Fairhurst, Steven J. Charlton, Dmitry B. Veprintsev
المصدر: Pharmacology Research & Perspectives, Vol 10, Iss 4, Pp n/a-n/a (2022)
مصطلحات موضوعية: adrenergicbeta‐blockers, kinetic selectivity, physicochemical properties, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2052-1707
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المؤلفون: Robin A. Fairhurst, Pascal Furet, Patricia Imbach-Weese, Frédéric Stauffer, Heinrich Rueeger, Clive McCarthy, Sebastien Ripoche, Susanne Oswald, Bertrand Arnaud, Aline Jary, Michel Maira, Christian Schnell, Daniel A. Guthy, Markus Wartmann, Michael Kiffe, Sandrine Desrayaud, Francesca Blasco, Toni Widmer, Frank Seiler, Sascha Gutmann, Mark Knapp, Giorgio Caravatti
المصدر: Journal of Medicinal Chemistry. 65:8345-8379
مصطلحات موضوعية: Phosphatidylinositol 3-Kinases, Cell Line, Tumor, Drug Discovery, Aminopyridines, Molecular Medicine, Antineoplastic Agents, Organic Chemicals, Protein Kinase Inhibitors, Phosphoinositide-3 Kinase Inhibitors
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المؤلفون: Diana Graus Porta, William R. Sellers, Francesco Hofmann, Jutta Blank, Pascal Furet, Robert Mah, Catherine Leblanc, Nicole Buschmann, Thomas Knoepfel, Audrey Kauffmann, Masato Murakami, Patrizia Barzaghi-Rinaudo, Youzhen Wang, Armin Wolf, Philippe Couttet, Heiko S. Schadt, Jacqueline Kinyamu-Akunda, Markus Wartmann, Mario Centeleghe, Dario Sterker, Michael Kiffe, Robin A. Fairhurst, Christelle Stamm, Alexandra Buhles, Flavia Adler, Andreas Weiss
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de614aa92fc53e000078388a9034229
https://doi.org/10.1158/1535-7163.22506502.v1 -
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المؤلفون: Diana Graus Porta, William R. Sellers, Francesco Hofmann, Jutta Blank, Pascal Furet, Robert Mah, Catherine Leblanc, Nicole Buschmann, Thomas Knoepfel, Audrey Kauffmann, Masato Murakami, Patrizia Barzaghi-Rinaudo, Youzhen Wang, Armin Wolf, Philippe Couttet, Heiko S. Schadt, Jacqueline Kinyamu-Akunda, Markus Wartmann, Mario Centeleghe, Dario Sterker, Michael Kiffe, Robin A. Fairhurst, Christelle Stamm, Alexandra Buhles, Flavia Adler, Andreas Weiss
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::855b9cca12680f3ffc27bb3edd85e4d5
https://doi.org/10.1158/1535-7163.22506505.v1 -
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المؤلفون: Diana Graus Porta, William R. Sellers, Francesco Hofmann, Jutta Blank, Pascal Furet, Robert Mah, Catherine Leblanc, Nicole Buschmann, Thomas Knoepfel, Audrey Kauffmann, Masato Murakami, Patrizia Barzaghi-Rinaudo, Youzhen Wang, Armin Wolf, Philippe Couttet, Heiko S. Schadt, Jacqueline Kinyamu-Akunda, Markus Wartmann, Mario Centeleghe, Dario Sterker, Michael Kiffe, Robin A. Fairhurst, Christelle Stamm, Alexandra Buhles, Flavia Adler, Andreas Weiss
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8a8adc6be4db10400fb7b3afdb43e38
https://doi.org/10.1158/1535-7163.22506514.v1 -
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المؤلفون: Diana Graus Porta, William R. Sellers, Francesco Hofmann, Jutta Blank, Pascal Furet, Robert Mah, Catherine Leblanc, Nicole Buschmann, Thomas Knoepfel, Audrey Kauffmann, Masato Murakami, Patrizia Barzaghi-Rinaudo, Youzhen Wang, Armin Wolf, Philippe Couttet, Heiko S. Schadt, Jacqueline Kinyamu-Akunda, Markus Wartmann, Mario Centeleghe, Dario Sterker, Michael Kiffe, Robin A. Fairhurst, Christelle Stamm, Alexandra Buhles, Flavia Adler, Andreas Weiss
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::13e8f6230bcc0ef53c3f3f3f81212e3c
https://doi.org/10.1158/1535-7163.c.6538417.v1 -
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المؤلفون: David A. Sykes, Mireia Jiménez‐Rosés, John Reilly, Robin A. Fairhurst, Steven J. Charlton, Dmitry B. Veprintsev
المصدر: Pharmacology Research & Perspectives. 10
مصطلحات موضوعية: Neurology, General Pharmacology, Toxicology and Pharmaceutics
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8
المؤلفون: Christelle Stamm, Pierre Nimsgern, Thomas Knoepfel, Jasmin Wirth, Michel Niklaus, Diana Graus-Porta, Alberto Del Rio Espinola, Dario Sterker, Michael Kiffe, Nicolas Warin, Van Huy Luu, Mario Madoerin, Robert Mah, Jacqueline Kinyamu-Akunda, Robin Alec Fairhurst, Milen Todorov, Nicole Buschmann, Sebastien Ripoche, Nils Ostermann, Inga Galuba, Philippe Couttet, Catherine Leblanc, Alexandra Buhles, Jutta Blank, Flavia Adler, Wolfgang Jahnke, Chao Zou, Joerg Berghausen, Andreas Weiss, Pascal Furet, Heiko Schadt, Johannes Voshol, Markus Wartmann, Joerg Trappe
المصدر: Journal of Medicinal Chemistry. 63:12542-12573
مصطلحات موضوعية: Receptor complex, Pyridines, Sequence alignment, Molecular Dynamics Simulation, Piperazines, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Dogs, Cell Line, Tumor, Drug Discovery, Animals, Structure–activity relationship, Receptor, Fibroblast Growth Factor, Type 4, Amino Acid Sequence, Cysteine, Kinase activity, Binding site, Protein Kinase Inhibitors, Cell Proliferation, Binding Sites, Liver Neoplasms, Hemithioacetal, Fibroblast growth factor receptor 4, Xenograft Model Antitumor Assays, Rats, chemistry, Biochemistry, Drug Design, Hepatocytes, Microsomes, Liver, Molecular Medicine, Half-Life
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المؤلفون: David A. Sykes, Steven J. Charlton, John Reilly, Dmitry B. Veprintsev, Robin Alec Fairhurst, Mireia Jiménez-Rosés
مصطلحات موضوعية: Partition coefficient, Hydrophobic effect, Chemistry, Kinetics, Biophysics, Synthetic membrane, Molecule, Biological membrane, Selectivity, Receptor–ligand kinetics
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::065ce31f32613d2fe60719a6c668d76c
https://doi.org/10.1101/2021.08.31.458064 -
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المؤلفون: Dean F. Rigel, Berengere Dumotier, Brian Peter Richardson, Thomas Ullrich, Moise Azria, Estelle Lach-Trifilieff, Shinji Hatakeyama, David J. Glass, Julian Bösch, David A. Sykes, Michael Kiffe, Ngoc-Hong Nguyen, Jeffrey Tsao, Steven J. Charlton, Magdalena Koziczak-Holbro, Robin Alec Fairhurst, Marie Jourdain, Ludivine Flotte, Yuichiro Adachi
المصدر: Journal of Pharmacology and Experimental Therapeutics. 369:188-199
مصطلحات موضوعية: 0301 basic medicine, Pharmacology, Agonist, Intrinsic activity, Myogenesis, medicine.drug_class, Chemistry, Skeletal muscle, Muscle hypertrophy, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, Functional selectivity, medicine, Molecular Medicine, Myocyte, Formoterol, 030217 neurology & neurosurgery, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6da56dc65829abdb607bc5857ac885a8
https://doi.org/10.1124/jpet.118.255307
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