المؤلفون: Rogawski DS; Department of Neurology and Neurological Sciences, Stanford Medicine, Palo Alto, California., Tong E; Department of Radiology, Stanford Medicine, Palo Alto, California., Campen C; Department of Neurology and Neurological Sciences, Stanford Medicine, Palo Alto, California.

المصدر: The Journal of pediatrics [J Pediatr] 2023 Oct; Vol. 261, pp. 113571. Date of Electronic Publication: 2023 Jun 18.

نوع المنشور: Case Reports

بيانات الدورية: Publisher: Mosby Country of Publication: United States NLM ID: 0375410 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6833 (Electronic) Linking ISSN: 00223476 NLM ISO Abbreviation: J Pediatr Subsets: MEDLINE

مواضيع طبية MeSH: Neurofibromatosis 1*/diagnosis , Neurofibromatosis 1*/genetics , Neurofibromatoses*, Humans ; Spine ; Phenotype ; Mutation

المؤلفون: Rogawski DS; Department of Neurology and Neurological Sciences, Stanford Medicine, Palo Alto, CA, USA., Nirschl JJ; Department of Pathology, Stanford Medicine, Palo Alto, CA, USA., McDonald J; Department of Neurology and Neurological Sciences, Stanford Medicine, Palo Alto, CA, USA., Nie E; Department of Neurology and Neurological Sciences, Stanford Medicine, Palo Alto, CA, USA., Schwartz NU; Department of Neurology and Neurological Sciences, Stanford Medicine, Palo Alto, CA, USA., Vogel H; Department of Pathology, Stanford Medicine, Palo Alto, CA, USA., Scott BJ; Department of Neurology and Neurological Sciences, Stanford Medicine, Palo Alto, CA, USA., Gold CA; Department of Neurology and Neurological Sciences, Stanford Medicine, Palo Alto, CA, USA., Kipp LB; Department of Neurology and Neurological Sciences, Stanford Medicine, Palo Alto, CA, USA.

المصدر: Multiple sclerosis (Houndmills, Basingstoke, England) [Mult Scler] 2022 Sep; Vol. 28 (10), pp. 1651-1654.

نوع المنشور: Case Reports; Journal Article

بيانات الدورية: Publisher: SAGE Publications Country of Publication: England NLM ID: 9509185 Publication Model: Print Cited Medium: Internet ISSN: 1477-0970 (Electronic) Linking ISSN: 13524585 NLM ISO Abbreviation: Mult Scler Subsets: MEDLINE

مواضيع طبية MeSH: Central Nervous System Neoplasms* , Histiocytic Sarcoma*/diagnosis, Area Postrema ; Diagnosis, Differential ; Female ; Humans ; Magnetic Resonance Imaging ; Middle Aged ; Neuromyelitis Optica/diagnostic imaging

المؤلفون: Rogawski DS; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Deng J; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Li H; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Miao H; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Borkin D; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Purohit T; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Song J; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Chase J; Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA., Li S; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Ndoj J; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Klossowski S; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Kim E; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Mao F; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Zhou B; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Ropa J; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.; Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, USA., Krotoska MZ; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Jin Z; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Ernst P; Department of Pediatrics, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA., Feng X; Department of Pathology and Laboratory Medicine, Cincinnati Children's Hospital, Cincinnati, OH, USA., Huang G; Department of Pathology and Laboratory Medicine, Cincinnati Children's Hospital, Cincinnati, OH, USA., Nishioka K; Department of Internal Medicine Musashimurayama Hospital, Enoki 1-1-5, Musashimurayama, Tokyo, Japan., Kelly S; Division of Hematology-Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., He M; College of Pharmacy, University of Michigan, Ann Arbor, MI, USA., Wen B; College of Pharmacy, University of Michigan, Ann Arbor, MI, USA., Sun D; College of Pharmacy, University of Michigan, Ann Arbor, MI, USA., Muntean A; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Dou Y; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Maillard I; Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.; Division of Hematology-Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Cierpicki T; Department of Pathology, University of Michigan, Ann Arbor, MI, USA. tomaszc@umich.edu., Grembecka J; Department of Pathology, University of Michigan, Ann Arbor, MI, USA. jolantag@med.umich.edu.

المصدر: Nature communications [Nat Commun] 2021 May 14; Vol. 12 (1), pp. 2792. Date of Electronic Publication: 2021 May 14.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*pharmacology , DNA-Binding Proteins/*antagonists & inhibitors , Enzyme Inhibitors/*pharmacology , Histone-Lysine N-Methyltransferase/*antagonists & inhibitors , Leukemia/*drug therapy , Leukemia/*enzymology, Animals ; Antineoplastic Agents/chemistry ; Catalytic Domain/drug effects ; Catalytic Domain/genetics ; Cell Line, Tumor ; Cell Transformation, Neoplastic/drug effects ; Cell Transformation, Neoplastic/genetics ; Crystallography, X-Ray ; DNA-Binding Proteins/chemistry ; DNA-Binding Proteins/genetics ; Drug Design ; Drug Discovery ; Enzyme Inhibitors/chemistry ; Female ; Histone-Lysine N-Methyltransferase/chemistry ; Histone-Lysine N-Methyltransferase/genetics ; Humans ; Leukemia/genetics ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Models, Molecular ; Myeloid-Lymphoid Leukemia Protein/genetics ; Oncogenes ; Protein Domains ; Recombinant Fusion Proteins/genetics

المؤلفون: Huang H; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Howard CA; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.; Program in Chemical Biology, University of Michigan, Ann Arbor, MI, USA., Zari S; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Cho HJ; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Shukla S; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Li H; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.; Program in Chemical Biology, University of Michigan, Ann Arbor, MI, USA., Ndoj J; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., González-Alonso P; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Nikolaidis C; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Abbott J; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Rogawski DS; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Potopnyk MA; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Kempinska K; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Miao H; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Purohit T; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Henderson A; Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA., Mapp A; Program in Chemical Biology, University of Michigan, Ann Arbor, MI, USA.; Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA., Sulis ML; Department of Pediatric Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Ferrando A; Institute for Cancer Genetics, Columbia University, New York, NY, USA.; Department of Systems Biology, Columbia University, New York, NY, USA.; Department of Pathology & Cell Biology, Columbia University, New York, NY, USA.; Department of Pediatrics, Columbia University, New York, NY, USA., Grembecka J; Department of Pathology, University of Michigan, Ann Arbor, MI, USA. jolantag@umich.edu.; Program in Chemical Biology, University of Michigan, Ann Arbor, MI, USA. jolantag@umich.edu., Cierpicki T; Department of Pathology, University of Michigan, Ann Arbor, MI, USA. tomaszc@umich.edu.; Program in Chemical Biology, University of Michigan, Ann Arbor, MI, USA. tomaszc@umich.edu.; Department of Biophysics, University of Michigan, Ann Arbor, MI, USA. tomaszc@umich.edu.

المصدر: Nature chemical biology [Nat Chem Biol] 2020 Dec; Vol. 16 (12), pp. 1403-1410. Date of Electronic Publication: 2020 Aug 31.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Regulation, Leukemic*, Antineoplastic Agents/*pharmacology , Enzyme Inhibitors/*pharmacology , Histone-Lysine N-Methyltransferase/*antagonists & inhibitors , Leukocytes/*drug effects , Nuclear Pore Complex Proteins/*genetics , Oncogene Proteins, Fusion/*antagonists & inhibitors, Antineoplastic Agents/chemical synthesis ; Binding Sites ; Enzyme Inhibitors/chemical synthesis ; Histone-Lysine N-Methyltransferase/genetics ; Histone-Lysine N-Methyltransferase/metabolism ; Homeodomain Proteins/genetics ; Homeodomain Proteins/metabolism ; Humans ; Kinetics ; Leukemia/drug therapy ; Leukemia/enzymology ; Leukemia/genetics ; Leukemia/pathology ; Leukocytes/enzymology ; Leukocytes/pathology ; Models, Molecular ; Myeloid Ecotropic Viral Integration Site 1 Protein/genetics ; Myeloid Ecotropic Viral Integration Site 1 Protein/metabolism ; Nuclear Pore Complex Proteins/metabolism ; Oncogene Proteins, Fusion/genetics ; Oncogene Proteins, Fusion/metabolism ; Protein Binding ; Protein Conformation, alpha-Helical ; Protein Conformation, beta-Strand ; Protein Interaction Domains and Motifs ; Signal Transduction ; Substrate Specificity ; Tumor Cells, Cultured

المؤلفون: Rogawski DS; Department of Pathology, Michigan Medicine, Ann Arbor., Rogawski MM; Department of Pathology, Michigan Medicine, Ann Arbor.

المصدر: JAMA [JAMA] 2018 Sep 11; Vol. 320 (10), pp. 1037.

نوع المنشور: Letter; Comment

بيانات الدورية: Publisher: American Medical Association Country of Publication: United States NLM ID: 7501160 Publication Model: Print Cited Medium: Internet ISSN: 1538-3598 (Electronic) Linking ISSN: 00987484 NLM ISO Abbreviation: JAMA Subsets: MEDLINE

مواضيع طبية MeSH: Mentoring* , Mentors*, Intergenerational Relations

المؤلفون: Rogawski DS; Department of Pediatrics, University of Michigan School of Medicine, Ann Arbor, Mich., Vitanza NA; Department of Pediatrics, Seattle Children's Hospital, Seattle, Wash., Gauthier AC; Yale School of Medicine, New Haven, Conn., Ramaswamy V; Division of Haematology/Oncology, Department of Pediatrics, Hospital for Sick Children, Toronto, ON, Canada., Koschmann C; Department of Pediatrics, University of Michigan School of Medicine, Ann Arbor, Mich. Electronic address: ckoschma@med.umich.edu.

المصدر: Translational research : the journal of laboratory and clinical medicine [Transl Res] 2017 Nov; Vol. 189, pp. 93-104. Date of Electronic Publication: 2017 Jul 08.

نوع المنشور: Journal Article; Review; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 101280339 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1810 (Electronic) Linking ISSN: 18781810 NLM ISO Abbreviation: Transl Res Subsets: MEDLINE

مواضيع طبية MeSH: Medical Oncology*, Nervous System Neoplasms/*genetics , Sequence Analysis, RNA/*methods, Gene Expression Regulation, Neoplastic ; Humans

المؤلفون: Horowitz S, Koepnick B, Martin R, Tymieniecki A, Winburn AA, Cooper S, Flatten J, Rogawski DS, Koropatkin NM, Hailu TT, Jain N, Koldewey P, Ahlstrom LS, Chapman MR, Sikkema AP, Skiba MA, Maloney FP, Beinlich FR, Popović Z, Baker D, Khatib F, Bardwell JC

مؤلفون مشاركون: Foldit Players, University of Michigan students

المصدر: Nature communications [Nat Commun] 2016 Oct 25; Vol. 7, pp. 13392. Date of Electronic Publication: 2016 Oct 25.

نوع المنشور: Journal Article; Published Erratum

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: PubMed not MEDLINE

المؤلفون: Horowitz S; Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109, USA.; Howard Hughes Medical Institute, University of Michigan, Ann Arbor, Michigan 48109, USA., Koepnick B; Department of Biochemistry, University of Washington, Seattle, Washington 98195, USA., Martin R; Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109, USA.; Biophysics Graduate Group, University of California, Berkeley, California 94720, USA., Tymieniecki A; Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109, USA.; Howard Hughes Medical Institute, University of Michigan, Ann Arbor, Michigan 48109, USA., Winburn AA; Center for Complex Networks and Systems Research, Department of Informatics, Indiana University, Bloomington, Indiana 47408, USA.; Program in Cognitive Science, Indiana University, 1900 E 10th Street, Bloomington, Indiana 47406, USA., Cooper S; Northeastern University, College of Computer and Information Science, Boston, Massachusetts 02115, USA., Flatten J; Department of Computer Science and Engineering, Center for Game Science, University of Washington, Seattle, Washington 98195, USA., Rogawski DS; Department of Pathology, University of Michigan, Ann Arbor, Michigan 48109, USA., Koropatkin NM; Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan 48109, USA., Hailu TT; Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109, USA.; ProQR Therapeutics NV., 2333 Leiden, The Netherlands., Jain N; Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109, USA., Koldewey P; Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109, USA.; Howard Hughes Medical Institute, University of Michigan, Ann Arbor, Michigan 48109, USA., Ahlstrom LS; Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109, USA.; Howard Hughes Medical Institute, University of Michigan, Ann Arbor, Michigan 48109, USA., Chapman MR; Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109, USA., Sikkema AP; Department of Biological Chemistry and Life Sciences Institute, University of Michigan, Ann Arbor, Michigan 48109, USA., Skiba MA; Department of Biological Chemistry and Life Sciences Institute, University of Michigan, Ann Arbor, Michigan 48109, USA., Maloney FP; Chemical Biology Doctoral Program, University of Michigan, Ann Arbor, Michigan 48109, USA., Beinlich FR; Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109, USA.; Institute of Complex Systems, Cellular Biophysics (ICS-4), Forschungszentrum, D-52428 Jülich, Germany., Popović Z; Department of Computer Science and Engineering, Center for Game Science, University of Washington, Seattle, Washington 98195, USA., Baker D; Department of Biochemistry, University of Washington, Seattle, Washington 98195, USA.; Institute for Protein Design, University of Washington, Seattle, Washington 98195, USA.; Howard Hughes Medical Institute, University of Washington, Seattle, Washington 98195, USA., Khatib F; Department of Computer and Information Science, University of Massachusetts Dartmouth, Dartmouth, Massachusetts 02747, USA., Bardwell JC; Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109, USA.; Howard Hughes Medical Institute, University of Michigan, Ann Arbor, Michigan 48109, USA.

مؤلفون مشاركون: Foldit Players, University of Michigan students

المصدر: Nature communications [Nat Commun] 2016 Sep 16; Vol. 7, pp. 12549. Date of Electronic Publication: 2016 Sep 16.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Curriculum* , Models, Chemical* , Software*, Crowdsourcing/*methods , Crystallography/*methods, Hydrolases/chemistry ; Hydrolases/classification ; Protein Conformation

المؤلفون: Rogawski DS; Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA., Grembecka J; Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA., Cierpicki T; Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA.

المصدر: Future medicinal chemistry [Future Med Chem] 2016 Sep; Vol. 8 (13), pp. 1589-607. Date of Electronic Publication: 2016 Aug 22.

نوع المنشور: Journal Article; Review; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Future Science Country of Publication: England NLM ID: 101511162 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1756-8927 (Electronic) Linking ISSN: 17568919 NLM ISO Abbreviation: Future Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*pharmacology , Enzyme Inhibitors/*pharmacology , Methyltransferases/*antagonists & inhibitors , Neoplasms/*drug therapy , Small Molecule Libraries/*pharmacology, Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Enzyme Inhibitors/chemical synthesis ; Enzyme Inhibitors/chemistry ; Humans ; Methyltransferases/genetics ; Methyltransferases/metabolism ; Neoplasms/metabolism ; Small Molecule Libraries/chemical synthesis ; Small Molecule Libraries/chemistry

المؤلفون: Rogawski DS; Department of Pathology, ‡Center for Stem Cell Biology, Life Sciences Institute, §Division of Hematology-Oncology, Department of Internal Medicine, and ∥Department of Cell and Developmental Biology, University of Michigan , Ann Arbor, Michigan 48109, United States., Ndoj J; Department of Pathology, ‡Center for Stem Cell Biology, Life Sciences Institute, §Division of Hematology-Oncology, Department of Internal Medicine, and ∥Department of Cell and Developmental Biology, University of Michigan , Ann Arbor, Michigan 48109, United States., Cho HJ; Department of Pathology, ‡Center for Stem Cell Biology, Life Sciences Institute, §Division of Hematology-Oncology, Department of Internal Medicine, and ∥Department of Cell and Developmental Biology, University of Michigan , Ann Arbor, Michigan 48109, United States., Maillard I; Department of Pathology, ‡Center for Stem Cell Biology, Life Sciences Institute, §Division of Hematology-Oncology, Department of Internal Medicine, and ∥Department of Cell and Developmental Biology, University of Michigan , Ann Arbor, Michigan 48109, United States., Grembecka J; Department of Pathology, ‡Center for Stem Cell Biology, Life Sciences Institute, §Division of Hematology-Oncology, Department of Internal Medicine, and ∥Department of Cell and Developmental Biology, University of Michigan , Ann Arbor, Michigan 48109, United States., Cierpicki T; Department of Pathology, ‡Center for Stem Cell Biology, Life Sciences Institute, §Division of Hematology-Oncology, Department of Internal Medicine, and ∥Department of Cell and Developmental Biology, University of Michigan , Ann Arbor, Michigan 48109, United States.

المصدر: Biochemistry [Biochemistry] 2015 Sep 08; Vol. 54 (35), pp. 5401-13. Date of Electronic Publication: 2015 Aug 25.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4995 (Electronic) Linking ISSN: 00062960 NLM ISO Abbreviation: Biochemistry Subsets: MEDLINE

مواضيع طبية MeSH: DNA-Binding Proteins/*chemistry , DNA-Binding Proteins/*metabolism , Transcription Factors/*chemistry , Transcription Factors/*metabolism, Crystallography, X-Ray ; Enzyme Activation/physiology ; Histone Methyltransferases ; Histone-Lysine N-Methyltransferase/chemistry ; Histone-Lysine N-Methyltransferase/metabolism ; Protein Structure, Secondary ; Protein Structure, Tertiary