المؤلفون: Roger M. Lane, Taher Darreh-Shori, Candice Junge, Dan Li, Qingqing Yang, Amanda L. Edwards, Danielle L. Graham, Katrina Moore, Catherine J. Mummery

المصدر: BMC Neurology, Vol 24, Iss 1, Pp 1-16 (2024)

مصطلحات موضوعية: Butyrylcholinesterase, Cholinergic, Glial activation, Innate immune, Apolipoprotein E, Amyloid, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1471-2377

URL الوصول: https://doaj.org/article/730fc122897643a1aee9109ee499d3ab

المؤلفون: Catherine J. Mummery, Anne Börjesson-Hanson, Daniel J. Blackburn, Everard G. B. Vijverberg, Peter Paul De Deyn, Simon Ducharme, Michael Jonsson, Anja Schneider, Juha O. Rinne, Albert C. Ludolph, Ralf Bodenschatz, Holly Kordasiewicz, Eric E. Swayze, Bethany Fitzsimmons, Laurence Mignon, Katrina M. Moore, Chris Yun, Tiffany Baumann, Dan Li, Daniel A. Norris, Rebecca Crean, Danielle L. Graham, Ellen Huang, Elena Ratti, C. Frank Bennett, Candice Junge, Roger M. Lane

المساهمون: Neurology, Amsterdam Neuroscience - Neurodegeneration, Molecular Neuroscience and Ageing Research (MOLAR)

المصدر: Nature medicine 29(6), 1437-1447 (2023). doi:10.1038/s41591-023-02326-3
Mummery, C J, Börjesson-Hanson, A, Blackburn, D J, Vijverberg, E G B, de Deyn, P P, Ducharme, S, Jonsson, M, Schneider, A, Rinne, J O, Ludolph, A C, Bodenschatz, R, Kordasiewicz, H, Swayze, E E, Fitzsimmons, B, Mignon, L, Moore, K M, Yun, C, Baumann, T, Li, D, Norris, D A, Crean, R, Graham, D L, Huang, E, Ratti, E, Bennett, C F, Junge, C & Lane, R M 2023, ' Tau-targeting antisense oligonucleotide MAPTRx in mild Alzheimer’s disease : a phase 1b, randomized, placebo-controlled trial ', Nature Medicine, vol. 29, no. 6, pp. 1437-1447 . https://doi.org/10.1038/s41591-023-02326-3
Nature Medicine. Nature Publishing Group
Nature Medicine, 29, 1437-1447. Nature Publishing Group

مصطلحات موضوعية: General Medicine, ddc:610, General Biochemistry, Genetics and Molecular Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a4826e86379fe0686cd40f5d60108ba
https://doi.org/10.1038/s41591-023-02326-3

المؤلفون: Catherine J Mummery, Candice Junge, Holly B Kordasiewicz, Laurence Mignon, Katrina M Moore, Chris Yun, Tiffany L Baumann, Dan Li, Daniel A Norris, Rebecca Crean, Danielle Graham, Ellen Huang, Elena Ratti, Roger M Lane

المصدر: Alzheimer's & Dementia. 17

مصطلحات موضوعية: Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, Neurology (clinical), Geriatrics and Gerontology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::36e8adff8866a7530fffbf1a0ca81ae9
https://doi.org/10.1002/alz.051871

المؤلفون: Roger M. Lane, Martin R. Farlow

المصدر: Journal of Lipid Research, Vol 46, Iss 5, Pp 949-968 (2005)

مصطلحات موضوعية: long-chain polyunsaturated essential fatty acid, cholesterol, carbohydrate, lipid raft, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S002222752033978X; https://doaj.org/toc/0022-2275

URL الوصول: https://doaj.org/article/4b11573a5d0c4feb89b3451af89b0391

المؤلفون: Nicholas Ah Mew, Wado Akamatsu, Hasan Orhan Akman, Afnan AlHakeem, Koji Aoyama, Rafael Artuch, Michael Beck, C. Frank Bennett, Gerard T. Berry, D. Montgomery Bissell, Brenda Canine, C. Thomas Caskey, Widler Casy, Patrick F. Chinnery, David T. Chuang, Emily K. Cook, Rody P. Cox, Philip L. De Jager, Didem Demirbas, Robert J. Desnick, Salvatore DiMauro, Florian S. Eichler, Bernice Elger, Valentina Emmanuele, Patricia Evans, Brent L. Fogel, Àngels García-Cazorla, Cinzia Gellera, Sailaja Golla, Kimberly Goodspeed, Sidney M. Gospe, Steven J. Gray, Andrea L. Gropman, Yian Gu, Renzo Guerrini, Teresa M. Gunn, Una Hadziahmetovic, Darrah Haffner, R.J. Hagerman, Tamar Harel, Elizabeth Head, Rita Horvath, Yasushi Hosoi, Ying-Chen Claire Hou, Jane Hsiao, Hiroyuki Ishiura, Clifford R. Jack, Vikram Jakkamsetti, William G. Johnson†, Fabrice Jotterand, John P. Kane, Olga Khorkova, Chisato Kinoshita, Sanne E. Klompe, Lisa M. Koehl, Michael C. Kruer, Walter A. Kukull, Roger M. Lane, Joseph H. Lee, M.J. Leigh, Qinglan Ling, James R. Lupski, Paola Luzi, Qian Ma, Gustavo H.B. Maegawa, Mary J. Malloy, Seth S. Margolis, Isaac Marin-Valencia, James A. Mastrianni, Dena Matalon, Reuben Matalon, Kimberlee Michals Matalon Rd, Jennifer M. Mathews, Richard Mayeux, Jennifer McCurdy, Meira R. Meltzer, John H. Menkes†, Justin Miron, Jun Mitsui, Hiroaki Miyajima, Lisa M. Monteggia, Mary Ann Morris, Hugo W. Moser†, Melissa E. Murray, Toshio Nakaki, Nathalie Nilsson, Ichizo Nishino, Sandra M.H. Nordlie, Robert L. Nussbaum, William L. Nyhan, Hideyuki Okano, Sergio Padilla-Lopez, Elena Parrini, Juan M. Pascual, Gregory M. Pastores, Shailendra B. Patel, Marc C. Patterson, Izabella A. Pena, Cynthia Picard, Judes Poirier, Jennifer E. Posey, Gerald V. Raymond, William Renthal, David S. Rosenblatt, Francis Rossignol, Gerald Salen, Konrad Sandhoff, Raphael Schiffmann, Detlev Schindler, Frederick A. Schmitt, Susanne A. Schneider, Eric A. Schon, Edward H. Schuchman, Margretta Reed Seashore, Frances C. Shaffo, Michael Shevell, Sarah E. Sinnett, Myriam Srour, Samuel H. Sternberg, Kazuma Sugie, Kristen L. Szabla, Franco Taroni, Marina Tedeschi Dauar, Shoji Tsuji, Wendy R. Uhlmann, Clara van Karnebeek, Kathryn L. Van Pelt, Prashanthi Vemuri, Charles P. Venditti, Claes Wahlestedt, Bruce Wang, David Watkins, David A. Wenger, Charles A. Williams, Golder N. Wilson, Barry Wolf, R. Max Wynn, Hung-Chun Yu

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::57d33606a0dd70f9459d3237b2c69dcb
https://doi.org/10.1016/b978-0-12-813955-4.00079-9

المؤلفون: V. Schlegel, Roger M. Lane, G. Hooper, L. Boak, A. Nicotra, Blair R. Leavitt, J. Chevure, Anne Smith, R. Doody, Sarah J. Tabrizi, Edward J. Wild, P. Sanwald Ducray, F. Bennett, Scott Schobel

المصدر: Journal of the Neurological Sciences. 405:26-27

مصطلحات موضوعية: Oncology, medicine.medical_specialty, business.industry, Extension study, Safety tolerability, medicine.disease, Neurology, Huntington's disease, Internal medicine, medicine, Biomarker (medicine), Neurology (clinical), Open label, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5a123d609dd2fc7a23d2545be8424a7e
https://doi.org/10.1016/j.jns.2019.10.260

المؤلفون: Roger M, Lane, Anne, Smith, Tiffany, Baumann, Marc, Gleichmann, Dan, Norris, C Frank, Bennett, Holly, Kordasiewicz

المصدر: Methods in molecular biology (Clifton, N.J.). 1780

مصطلحات موضوعية: Huntingtin Protein, Drug Evaluation, Preclinical, Brain, Oligonucleotides, Antisense, Rats, Translational Research, Biomedical, Disease Models, Animal, Macaca fascicularis, Mice, Huntington Disease, Treatment Outcome, Drug Development, Mutation, RNA Precursors, Animals, Humans, Targeted Gene Repair

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::677809dc2cb24da2a6325f2d538b1a03
https://pubmed.ncbi.nlm.nih.gov/29856033

المؤلفون: Roger M. Lane, Anne Torbeyns, Arif Khan, Boadie W. Dunlop, Delphine Hennicken, Craig Nelson, Richard H. Weisler, Michael E. Thase, Ming Zheng, Sanjay J. Mathew, Richard C. Shelton, Zubin Bhagwagar

المصدر: Journal of Clinical Psychopharmacology. 35:454-459

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Internationality, Randomization, Adolescent, law.invention, Depressive Disorder, Treatment-Resistant, Young Adult, chemistry.chemical_compound, Double-Blind Method, Randomized controlled trial, law, Internal medicine, medicine, Clinical endpoint, Humans, Duloxetine, Escitalopram, Pharmacology (medical), Prospective Studies, Adverse effect, Prospective cohort study, Aged, Depressive Disorder, Major, Dose-Response Relationship, Drug, business.industry, Middle Aged, Isoquinolines, Pyridazines, Clinical trial, Psychiatry and Mental health, Treatment Outcome, chemistry, Female, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::785965a0ad9c721a47b696a175281a9c
https://doi.org/10.1097/jcp.0000000000000335

المؤلفون: Roger M. Lane, Matthew Cahir, David Burt, Zubin Bhagwagar, Robert Risinger, Sanjay Keswani, Gunnar Antoni, Feng Luo, Lieuwe Appel, Ming Zheng, Wendy Hayes

المصدر: Psychopharmacology. 232(3)

مصطلحات موضوعية: Adult, Male, education, Pharmacology, Reuptake, Norepinephrine, Young Adult, Double-Blind Method, Dopamine, medicine, Humans, Neurotransmitter Uptake Inhibitors, Dopamine transporter, Serotonin Plasma Membrane Transport Proteins, Dopamine Plasma Membrane Transport Proteins, biology, Dose-Response Relationship, Drug, business.industry, digestive, oral, and skin physiology, Middle Aged, Isoquinolines, Neostriatum, Pyridazines, stomatognathic diseases, Norepinephrine transporter, Positron-Emission Tomography, biology.protein, Antidepressant, Female, Serotonin, Monoamine reuptake inhibitor, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55a84fdea99e46d0a62e342b8d6c8aed
https://pubmed.ncbi.nlm.nih.gov/25116481

المؤلفون: David C. Johnston, Yvon-Jacques Lavallie, Richard P. Swinson, John C. Pecknold, Rudradeo C. Bowen, Vratislav Hadrava, Roger M. Lane, Pratap Chokka, Saibal Nandy, Michael Van Ameringen, Elliot M. Goldner, John R. Walker

المصدر: Journal of Clinical Psychopharmacology. 20:636-644

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Generalized anxiety disorder, Placebo, law.invention, Double-Blind Method, Randomized controlled trial, law, Sertraline, Internal medicine, Confidence Intervals, Secondary Prevention, medicine, Humans, Pharmacology (medical), Psychiatry, Analysis of Variance, Chi-Square Distribution, Hazard ratio, Middle Aged, medicine.disease, Survival Analysis, Psychiatry and Mental health, Phobic Disorders, Tolerability, Relative risk, Clinical Global Impression, Female, Psychology, Selective Serotonin Reuptake Inhibitors, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf8703aea1706d404d8f5434d28a383c
https://doi.org/10.1097/00004714-200012000-00009