نتائج البحث - "Roger Meier"

المساهمون: University hospital of Zurich [Zurich], Universität Zürich [Zürich] = University of Zurich (UZH), Institute for Molecular Systems Biology [ETH Zurich] (IMSB), Department of Biology [ETH Zürich] (D-BIOL), Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology [Zürich] (ETH Zürich)- Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology [Zürich] (ETH Zürich), Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires - U1011 (RNMCD), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), CHU Lille, Scientific Center for Optical and Electron Microscopy (ScopeM), Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology [Zürich] (ETH Zürich), University of Groningen [Groningen], unité de recherche de l'institut du thorax UMR1087 UMR6291 (ITX), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Nantes Université - UFR de Médecine et des Techniques Médicales (Nantes Univ - UFR MEDECINE), Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), St George's, University of London, Laboratoire de Recherche Vasculaire Translationnelle (LVTS (UMR_S_1148 / U1148)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Université Sorbonne Paris Nord, AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université Saint-Joseph de Beyrouth (USJ), University of Copenhagen = Københavns Universitet (UCPH), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Institut Cochin (IC UM3 (UMR 8104 / U1016)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), AP-HP. Université Paris Saclay, Université de Versailles Saint-Quentin-en-Yvelines - UFR Sciences de la santé Simone Veil (UVSQ Santé), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Antwerp University Hospital [Edegem] (UZA), University of Antwerp (UA), University of Amsterdam [Amsterdam] (UvA), Columbia University [New York], University Hospital of Würzburg, University College of London [London] (UCL), 603091, ANR-10-LABX-46, 2015T068, CVON2017-2020, AOM06024, 2014/267, Pfizer: 24052829, European Molecular Biology Organization, EMBO: ALTF277-2014, Seventh Framework Programme, FP7, Sixth Framework Programme, FP6: LSHM-CT-2005-018734, Fondation Maladies Rares, FMR, International Atherosclerosis Society, IAS, British Heart Foundation, BHF, European Commission, EC, European Research Council, ERC: 694717, ANR 16-RHUS-0006, Agence Nationale de la Recherche, ANR: ANR-16-RHUS-0007, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, SNF: 310030-185109, 31003A-160126, Fonds De La Recherche Scientifique - FNRS, FNRS, Fonds Wetenschappelijk Onderzoek, FWO: 1802154 N, PG008/08, RG3008, Nederlandse Organisatie voor Wetenschappelijk Onderzoek, NWO: 184.021.007, Universität Zürich, UZH: FK-20-037, We acknowledge the use of data from BIOS-consortium ( http://wiki.bbmri.nl/wiki/BIOS_bios ) which is funded by BBMRI-NL (NWO project 184.021.007). Flow cytometry was performed with equipment of the flow cytometry facility, University of Zurich., This work was conducted as part of the TransCard project of the seventh Framework Program (FP7) granted by the European Commission, to J. Albert Kuivenhoven, A. Tybjaerg-Hansen, and A. von Eckardstein (number 603091) as well as partially the FP7 RESOLVE project (to J.T. Haas, B. Staels, A. Verhaegen, S. Francque, L. Van Gaal, and A. von Eckardstein) and the European Genomic Institute for Diabetes (EGID, ANR-10-LABX-46 to B. Staels). Additional work by A. von Eckardstein’s team was funded by the Swiss National Science Foundation (31003A-160126, 310030-185109) and the Swiss Systems X program (2014/267 [Medical Research and Development (MRD)] HDL-X). P. Zanoni received funding awards from the Swiss Atherosclerosis Society (Arbeitsgruppe Lipide und Atherosklerose [AGLA] and the DACH Society for Prevention of Cardiovascular Diseases). G. Panteloglou received funding from the University of Zurich (Forschungskredit, grant no. FK-20-037). J. Albert Kuivenhoven is an Established Investigator from the Dutch Heart Foundation (2015T068). J. Albert Kuivenhoven was also supported by GeniusII (CVON2017-2020). The Laboratory for Vascular Translational Science (L.V.T.S.) team is supported by Fondation Maladies Rares, Programme Hospitalier de Recherche Clinique (PHRC) (AOM06024), and the national project CHOPIN (CHolesterol Personalized Innovation), granted by the Agence Nationale de la Recherche (ANR-16-RHUS-0007). Y. Abou Khalil is supported by a grant from Ministère de l’Education Nationale et de la Technologie (France). J.T. Haas was supported by an EMBO Long Term Fellowship (ALTF277-2014). B. Staels is a recipient of an ERC Advanced Grant (no. 694717). Both are also supported by PreciNASH (ANR 16-RHUS-0006). Research at the Antwerp University Hospital was supported by the European Union: FP6 (HEPADIP Contract LSHM-CT-2005-018734). S. Francque has a senior clinical research fellowship from the Fund for Scientific Research (FWO) Flanders (1802154 N). S.E. Humphries received grants RG3008 and PG008/08 from the British Heart Foundation, and the support of the UCLH NIHR BRC. S.E. Humphries directs the UK Children’s FH Register which has been supported by a grant from Pfizer (24052829) given by the International Atherosclerosis Society., This work was conducted as part of the TransCard project of the seventh Framework Program (FP7) granted by the European Commission, to J. Albert Kuivenhoven, A. Tybjaerg-Hansen, and A. von Eckardstein (number 603091) as well as partially the FP7 RESOLVE project (to J.T. Haas, B. Staels, A. Verhaegen, S. Francque, L. Van Gaal, and A. von Eckardstein) and the European Genomic Institute for Diabetes (EGID, ANR-10-LABX-46 to B. Staels). Additional work by A. von Eckardstein's team was funded by the Swiss National Science Foundation (31003A-160126, 310030-185109) and the Swiss Systems X program (2014/267 [Medical Research and Development (MRD)] HDL-X). P. Zanoni received funding awards from the Swiss Atherosclerosis Society (Arbeitsgruppe Lipide und Atherosklerose [AGLA] and the DACH Society for Prevention of Cardiovascular Diseases). G. Panteloglou received funding from the University of Zurich (Forschungskredit, grant no. FK-20-037). J. Albert Kuivenhoven is an Established Investigator from the Dutch Heart Foundation (2015T068). J. Albert Kuivenhoven was also supported by GeniusII (CVON2017-2020). The Laboratory for Vascular Translational Science (L.V.T.S.) team is supported by Fondation Maladies Rares, Programme Hospitalier de Recherche Clinique (PHRC) (AOM06024), and the national project CHOPIN (CHolesterol Personalized Innovation), granted by the Agence Nationale de la Recherche (ANR-16-RHUS-0007). Y. Abou Khalil is supported by a grant from Minist?re de l'Education Nationale et de la Technologie (France). J.T. Haas was supported by an EMBO Long Term Fellowship (ALTF277-2014). B. Staels is a recipient of an ERC Advanced Grant (no. 694717). Both are also supported by PreciNASH (ANR 16-RHUS-0006). Research at the Antwerp University Hospital was supported by the European Union: FP6 (HEPADIP Contract LSHMCT- 2005-018734). S. Francque has a senior clinical research fellowship from the Fund for Scientific Research (FWO) Flanders (1802154 N). S.E. Humphries received grants RG3008 and PG008/08 from the British Heart Foundation, and the support of the UCLH NIHR BRC. S.E. Humphries directs the UK Children's FH Register which has been supported by a grant from Pfizer (24052829) given by the International Atherosclerosis Society., ANR-16-RHUS-0006,PreciNASH,PreciNASH(2016), ANR-16-RHUS-0007,CHOPIN,CHOPIN(2016), Center for Liver, Digestive and Metabolic Diseases (CLDM), Restoring Organ Function by Means of Regenerative Medicine (REGENERATE), HAL UVSQ, Équipe, Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires (RNMCD - U1011), Service d'Endocrinologie, Métabolisme et Prévention des Maladies Cardio-vasculaires [CHU Pitié-Salpêtrière], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)

المصدر: Zanoni, P, Panteloglou, G, Othman, A, Haas, J T, Meier, R, Rimbert, A, Futema, M, Khalil, Y A, Norrelykke, S F, Rzepiela, A J, Stoma, S, Stebler, M, Van Dijk, F, Wijers, M, Wolters, J C, Dalila, N, Huijkman, N C A, Smit, M, Gallo, A, Carreau, V, Philippi, A, Rabès, J P, Boileau, C, Visentin, M, Vonghia, L, Weyler, J, Francque, S, Verrijken, A, Verhaegen, A, Van Gaal, L, Van Der Graaf, A, Van Rosmalen, B V, Robert, J, Velagapudi, S, Yalcinkaya, M, Keel, M, Radosavljevic, S, Geier, A, Tybjaerg-Hansen, A, Varret, M, Rohrer, L, Humphries, S E, Staels, B, Van De Sluis, B, Kuivenhoven, J A & Von Eckardstein, A 2022, ' Posttranscriptional Regulation of the Human LDL Receptor by the U2-Spliceosome ', Circulation Research, vol. 130, no. 1, pp. 80-95 . https://doi.org/10.1161/CIRCRESAHA.120.318141
Circulation Research
Circulation Research, 2022, 130 (1), pp.80-95. ⟨10.1161/CIRCRESAHA.120.318141⟩
Circulation research
Circulation research, 130(1), 80-95. LIPPINCOTT WILLIAMS & WILKINS

مصطلحات موضوعية: Spliceosome, Physiology, RNA Splicing, Population, Hypercholesterolemia, Familial hypercholesterolemia, 030204 cardiovascular system & hematology, Biology, 03 medical and health sciences, 0302 clinical medicine, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Gene expression, medicine, Humans, education, Gene, 030304 developmental biology, 0303 health sciences, Gene knockdown, education.field_of_study, Intron, Nuclear Proteins, Hep G2 Cells, medicine.disease, Molecular biology, Endocytosis, [SDV.MHEP.CSC] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Lipoproteins, LDL, Cholesterol, HEK293 Cells, Cardiovascular diseases, Liver, Receptors, LDL, Mutation, LDL receptor, Hepatocytes, Spliceosomes, lipids (amino acids, peptides, and proteins), Human medicine, Cardiology and Cardiovascular Medicine

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e7252f24e599e74af7d4245ca33b8f0
https://curis.ku.dk/portal/da/publications/posttranscriptional-regulation-of-the-human-ldl-receptor-by-the-u2spliceosome(80ba810e-1e80-4fb5-8616-1532e1482dba).html

6

The U2-spliceosome and its interactors regulate the levels and activity of the LDL receptor in humans

المؤلفون: Joost Weyler, Grigorios Panteloglou, B. Van De Sluis, Joel T. Haas, Anne Tybjærg-Hansen, Luisa Vonghia, Ann Verhaegen, Catherine Boileau, Alaa Othman, A. Van Der Graaf, Anne Philippi, Marieke Smit, Sven Francque, Mathilde Varret, Jan Albert Kuivenhoven, Srividya Velagapudi, B.V. Van Rosmalen, L. Van Gaal, Y. Abou Khalil, Justina C. Wolters, Antoine Rimbert, Simon F. Norrelykke, Roger Meier, Bart Staels, Lucia Rohrer, Andrzej J. Rzepiela, Paolo Zanoni, Andreas Geier, Michaela Keel, Valérie Carreau, S.E. Humphries, Michael Stebler, M. Futema, Szymon Stoma, N. Dalila, Melinde Wijers, Nicolette C. A. Huijkman, An Verrijken, Antonio Gallo, Jean-Pierre Rabès, A. von Eckardstein, Silvija Radosavljevic, M. Yalcinkaya, F. van Dijk, Michele Visentin

المصدر: Atherosclerosis. 315:e15

مصطلحات موضوعية: Spliceosome, Chemistry, LDL receptor, Cardiology and Cardiovascular Medicine, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::53efccc03f9a6b90c053ab6e26478224
https://doi.org/10.1016/j.atherosclerosis.2020.10.058

View record from ScienceDirect

Full Text via ClinicalKey

7

PIKfyve/Fab1 is required for efficient V-ATPase and hydrolase delivery to phagosomes, phagosomal killing, and restriction of Legionella infection

المؤلفون: Catherine M Buckley, Victoria L Heath, Aurélie Guého, Cristina Bosmani, Paulina Knobloch, Phumzile Sikakana, Nicolas Personnic, Stephen K Dove, Robert H Michell, Roger Meier, Hubert Hilbi, Thierry Soldati, Robert H Insall, Jason S King

المساهمون: University of Zurich, King, Jason S

المصدر: PLOS Pathogens, Vol. 15, No 2 (2019) P. e1007551
PLoS Pathogens, 15 (2)
PLoS Pathogens
PLoS Pathogens, Vol 15, Iss 2, p e1007551 (2019)

مصطلحات موضوعية: Phagocyte, Hydrolases, Dictyosteliomycota, 2405 Parasitology, Pathology and Laboratory Medicine, Phosphatidylinositols, Legionella pneumophila, Dictyostelium discoideum, Phosphatidylinositol 3-Kinases, PIKFYVE, 0302 clinical medicine, Phosphatidylinositol Phosphates, Phagosomes, Medicine and Health Sciences, Dictyostelium, Biology (General), Amoebas, Phagosome, Protozoans, Adenosine Triphosphatases, 0303 health sciences, biology, Early phagosome, 10179 Institute of Medical Microbiology, Dictyostelium Discoideum, 030302 biochemistry & molecular biology, 2404 Microbiology, Eukaryota, Protists, Bacterial Pathogens, 3. Good health, Cell biology, Protein Transport, Intracellular Pathogens, medicine.anatomical_structure, Slime Molds, Experimental Organism Systems, Medical Microbiology, Cell Processes, ddc:540, Cellular Structures and Organelles, Pathogens, Research Article, QH301-705.5, Phagocytosis, Immunology, Legionella, 610 Medicine & health, Research and Analysis Methods, Microbiology, Cell Line, 03 medical and health sciences, Model Organisms, 1311 Genetics, Virology, Phagosome maturation, Genetics, medicine, 1312 Molecular Biology, Animals, Humans, Vesicles, Microbial Pathogens, Molecular Biology, 030304 developmental biology, 2403 Immunology, Legionellosis, Protozoan Infections, Bacteria, Protozoan Models, Macrophages, Intracellular parasite, Organisms, Biology and Life Sciences, Cell Biology, RC581-607, biology.organism_classification, Animal Studies, 2406 Virology, 570 Life sciences, Parasitology, Immunologic diseases. Allergy, 030217 neurology & neurosurgery

وصف الملف: journal.ppat.1007551.pdf - application/pdf; application/pdf; application/application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a716e0ee018b0e438ede03cdc54e1d57
https://archive-ouverte.unige.ch/unige:156858

Find this article in full text from ProQuest

8

VEGF-A regulates cellular localization of SR-BI as well as transendothelial transport of HDL but not LDL

المؤلفون: Paolo Zanoni, Simon F. Norrelykke, Arnold von Eckardstein, Szymon Stoma, Srividya Velagapudi, Mustafa Yalcinkaya, Lucia Rohrer, Antonio Piemontese, Damir Perisa, Roger Meier, Michael Stebler, Andrzej J. Rzepiela

المساهمون: University of Zurich, Rohrer, Lucia

مصطلحات موضوعية: 0301 basic medicine, Vascular wall, Vascular Endothelial Growth Factor A, VEGF receptors, 610 Medicine & health, 030204 cardiovascular system & hematology, Biology, Transfection, p38 Mitogen-Activated Protein Kinases, 2705 Cardiology and Cardiovascular Medicine, 03 medical and health sciences, 0302 clinical medicine, 540 Chemistry, Humans, Protein Kinase Inhibitors, Cellular localization, Cells, Cultured, Phosphoinositide-3 Kinase Inhibitors, 10038 Institute of Clinical Chemistry, Endothelial Cells, Scavenger Receptors, Class B, Vascular Endothelial Growth Factor Receptor-2, Cell biology, High-Throughput Screening Assays, Lipoproteins, LDL, Protein Transport, 030104 developmental biology, Biochemistry, biology.protein, RNA Interference, lipids (amino acids, peptides, and proteins), Phosphatidylinositol 3-Kinase, Cardiology and Cardiovascular Medicine, Lipoproteins, HDL, Proto-Oncogene Proteins c-akt, Signal Transduction

وصف الملف: ZORA138020.pdf - application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f6dfe2df344f81a83e70f750ad84de2
https://www.zora.uzh.ch/id/eprint/138020/

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Specific inhibition of diverse pathogens in human cells by synthetic microRNA-like oligonucleotides inferred from RNAi screens

المؤلفون: Christian von Mering, Andreas Kaufmann, Shyan Huey Low, Mario Emmenlauer, Daniel Andritschke, Ari Helenius, Christoph Dehio, Andrea Franceschini, Neha Daga, Sabrina Dilling, Alain Casanova, Roger Meier, Saskia Kreibich, Lucas Pelkmans, Raquel Conde-Álvarez, Pauli Rämö, Wolf-Dietrich Hardt

المساهمون: University of Zurich, Helenius, Ari

المصدر: Proceedings of the National Academy of Sciences of the United States of America
Dadun. Depósito Académico Digital de la Universidad de Navarra
instname
Proceedings of the National Academy of Sciences

مصطلحات موضوعية: Salmonella typhimurium, Small interfering RNA, Bunyaviridae, Oligonucleotides, Brucella abortus, High-throughput RNAi screening, Biology, UFSP13-7 Evolution in Action: From Genomes to Ecosystems, 03 medical and health sciences, 0302 clinical medicine, RNA interference, microRNA, Humans, RNA, Small Interfering, Gene, 030304 developmental biology, Genetics, 0303 health sciences, Messenger RNA, 1000 Multidisciplinary, Multidisciplinary, Base Sequence, Antimicrobials, Oligonucleotide, Phenotype, 10124 Institute of Molecular Life Sciences, MicroRNAs, Genes, Bacterial, 030220 oncology & carcinogenesis, 570 Life sciences, biology, RNA Interference, Target mrna, U7 Systems Biology / Functional Genomics, HeLa Cells

وصف الملف: accepted_manuscript.pdf - application/pdf; PNAS-2014-Franceschini-4548-53.pdf - application/pdf; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec925518c04342c15c56f922510e9eb3

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Genome-wide small interfering RNA screens reveal VAMP3 as a novel host factor required for Uukuniemi virus late penetration

المؤلفون: Christian von Mering, Peter Horvath, Roger Meier, Ari Helenius, Marilou Tétard, Pierre-Yves Lozach, Andrea Franceschini, Roberta Mancini

المساهمون: Institute of Biochemistry [ETH Zürich], Department of Biology [ETH Zürich] (D-BIOL), Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology [Zürich] (ETH Zürich)- Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology [Zürich] (ETH Zürich), Swiss Institute of Bioinformatics [Lausanne] (SIB), Université de Lausanne (UNIL), Institut Armand Frappier (INRS-IAF), Institut National de la Recherche Scientifique [Québec] (INRS)-Réseau International des Instituts Pasteur (RIIP), This work was supported by grants from InfectX to C.V.M., from theEuropean Research Council, the Swiss National Foundation for Research,ETH Zurich, and LipidX to A.H., and from the Natural Sciences andEngineering Research Council of Canada and the Banting Research Foundationto P.Y.L., University of Zurich

المصدر: Journal of Virology
Journal of Virology, American Society for Microbiology, 2014, 88 (15), pp.8565-78. ⟨10.1128/JVI.00388-14⟩

مصطلحات موضوعية: Small interfering RNA, 1109 Insect Science, Time Factors, Vesicle-Associated Membrane Protein 3, [SDV]Life Sciences [q-bio], Immunology, Endosomes, Biology, Microbiology, Virus, UFSP13-7 Evolution in Action: From Genomes to Ecosystems, Virology, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], microRNA, Gene silencing, Humans, Gene Silencing, Genetic Testing, RNA, Small Interfering, Host factor, 2403 Immunology, Uukuniemi virus, 2404 Microbiology, Lysosome-Associated Membrane Glycoproteins, Epithelial Cells, Virus Internalization, biology.organism_classification, 10124 Institute of Molecular Life Sciences, 3. Good health, Cell biology, Virus-Cell Interactions, Viral replication, Insect Science, Host-Pathogen Interactions, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, 2406 Virology, 570 Life sciences, biology, Bunyaviridae, U7 Systems Biology / Functional Genomics, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c66de2170bd5daa095910126f1208e0f

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