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1دورية أكاديمية
المؤلفون: Ravi S. Narayan, Piet Molenaar, Jian Teng, Fleur M. G. Cornelissen, Irene Roelofs, Renee Menezes, Rogier Dik, Tonny Lagerweij, Yoran Broersma, Naomi Petersen, Jhon Alexander Marin Soto, Eelke Brands, Philip van Kuiken, Maria C. Lecca, Kristiaan J. Lenos, Sjors G. J. G. In ‘t Veld, Wessel van Wieringen, Frederick F. Lang, Erik Sulman, Roel Verhaak, Brigitta G. Baumert, Lucas J. A. Stalpers, Louis Vermeulen, Colin Watts, David Bailey, Ben J. Slotman, Rogier Versteeg, David Noske, Peter Sminia, Bakhos A. Tannous, Tom Wurdinger, Jan Koster, Bart A. Westerman
المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2041-1723
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المؤلفون: Peter Sminia, Jan Theys, Bart A. Westerman, Brigitta G. Baumert, Lukas J.A. Stalpers, Daphne A. Haas-Kogan, Tom Würdinger, Ben J. Slotman, Jaap van den Berg, Rogier Dik, Hou Y.Y.E. Veldman, Tonny Lagerweij, Fleur M.G. Cornelissen, Paul L.G. Slangen, Ana Gasol, Ravi S. Narayan
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc0c910cffbb13d392e1d82fa7f189d
https://doi.org/10.1158/1535-7163.22504666.v1 -
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المؤلفون: Peter Sminia, Jan Theys, Bart A. Westerman, Brigitta G. Baumert, Lukas J.A. Stalpers, Daphne A. Haas-Kogan, Tom Würdinger, Ben J. Slotman, Jaap van den Berg, Rogier Dik, Hou Y.Y.E. Veldman, Tonny Lagerweij, Fleur M.G. Cornelissen, Paul L.G. Slangen, Ana Gasol, Ravi S. Narayan
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::99956e3c52b0c80f5b93b220beab0d8d
https://doi.org/10.1158/1535-7163.c.6537823.v1 -
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المؤلفون: Brigitta G. Baumert, Erik P. Sulman, Jan Koster, Rogier Dik, Yoran Broersma, Tonny Lagerweij, Rogier Versteeg, Lucas J A Stalpers, D. P. Noske, Irene Roelofs, Jhon Alexander Marin Soto, Sjors G J G In 't Veld, Peter Sminia, Naomi Petersen, Louis Vermeulen, Maria C. Lecca, Eelke Brands, Ravi S. Narayan, Bakhos A. Tannous, Renée X. de Menezes, David Bailey, Jian Teng, Bart A Westerman, Ben J. Slotman, Thomas Wurdinger, Piet Molenaar, Fleur M G Cornelissen, Roel G.W. Verhaak, Colin Watts, Frederick F. Lang, Kristiaan J. Lenos, Wessel N. van Wieringen, Philip van Kuiken
المساهمون: Oncogenomics, CCA - Cancer biology and immunology, Tytgat Institute for Liver and Intestinal Research, Center of Experimental and Molecular Medicine, Radiotherapy, AGEM - Re-generation and cancer of the digestive system, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, APH - Methodology, Radiation Oncology, Neurosurgery, Epidemiology and Data Science, Molecular cell biology and Immunology, Internal medicine
المصدر: Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature communications, 11(1):2935. Nature Publishing Group
Nature Communications, 11(1):2935
Narayan, R S, Molenaar, P, Teng, J, Cornelissen, F M G, Roelofs, I, Menezes, R, Dik, R, Lagerweij, T, Broersma, Y, Petersen, N, Marin Soto, J A, Brands, E, van Kuiken, P, Lecca, M C, Lenos, K J, Int Veld, S G J G, van Wieringen, W, Lang, F F, Sulman, E, Verhaak, R, Baumert, B G, Stalpers, L J A, Vermeulen, L, Watts, C, Bailey, D, Slotman, B J, Versteeg, R, Noske, D, Sminia, P, Tannous, B A, Wurdinger, T, Koster, J & Westerman, B A 2020, ' A cancer drug atlas enables synergistic targeting of independent drug vulnerabilities ', Nature Communications, vol. 11, no. 1, 2935 . https://doi.org/10.1038/s41467-020-16735-2, https://doi.org/10.1038/s41467-020-16735-2مصطلحات موضوعية: 0301 basic medicine, Drug, Cancer therapy, Computer science, Cell Survival, Science, media_common.quotation_subject, Cancer drugs, General Physics and Astronomy, Antineoplastic Agents, Breast Neoplasms, Computational biology, General Biochemistry, Genetics and Molecular Biology, Drug synergism, Article, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, Cell Line, Tumor, medicine, Animals, Humans, lcsh:Science, Cancer genetics, Melanoma, media_common, Multidisciplinary, Computational Biology, Drug Synergism, General Chemistry, medicine.disease, Computational biology and bioinformatics, Drug Combinations, 030104 developmental biology, Logistic Models, Drug screening, 030220 oncology & carcinogenesis, Pharmacogenomics, lcsh:Q, Glioblastoma
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المؤلفون: Ben J. Slotman, Rogier Dik, Godefridus J. Peters, Bart A. Westerman, Lukas J.A. Stalpers, Peter Sminia, Brigitta G. Baumert, Eelke Brands, Carlos Alexandre Fedrigo, Ravi S. Narayan
المساهمون: RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy, Radiotherapie, APH - Methodology, CCA - Cancer biology and immunology, Radiotherapy, Cancer Center Amsterdam, Other departments, Radiation Oncology, CCA - Cancer Treatment and quality of life, Neurosurgery, AGEM - Digestive immunity, Medical oncology laboratory
المصدر: BMC Cancer, 17:204. BioMed Central Ltd
Narayan, R S, Fedrigo, C A, Brands, E, Dik, R, Stalpers, L J A, Baumert, B G, Slotman, B J, Westerman, B A, Peters, G J & Sminia, P 2017, ' The allosteric AKT inhibitor MK2206 shows a synergistic interaction with chemotherapy and radiotherapy in glioblastoma spheroid cultures ', BMC Cancer, vol. 17, no. 1, 204 . https://doi.org/10.1186/s12885-017-3193-9
BMC Cancer
BMC cancer, 17(1). BioMed Central
BMC Cancer, 17(1):204. BioMed Centralمصطلحات موضوعية: 0301 basic medicine, Pathology, Cancer Research, PROGRESSION, PATHWAY, chemistry.chemical_compound, 0302 clinical medicine, Akt Inhibitor MK2206, MK2206, Phosphorylation, MICHAELIS-MENTEN, Brain Neoplasms, Drug Synergism, Glioma, SOLID TUMORS, CANCER, MALIGNANT GLIOMA, Dacarbazine, Synergy, Oncology, MK-2206, 030220 oncology & carcinogenesis, embryonic structures, AUTOPHAGY, Heterocyclic Compounds, 3-Ring, medicine.drug, Research Article, Signal Transduction, medicine.medical_specialty, Blotting, Western, 03 medical and health sciences, Cell Line, Tumor, Spheroids, Cellular, medicine, Temozolomide, Genetics, Humans, Protein kinase B, Antineoplastic Agents, Alkylating, PI3K/AKT/mTOR pathway, Cell Proliferation, Radiosensitization, business.industry, Akt, Spheroid, medicine.disease, 030104 developmental biology, chemistry, CELLS, Cancer research, KINETIC SYSTEMS, Phosphatidylinositol 3-Kinase, business, Glioblastoma, Proto-Oncogene Proteins c-akt, Spheroid cultures
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6THER-34. MEK BLOCKADE SYNERGISTICALLY INCREASES THE ANTI-TUMOR EFFECTS OF mTOR INHIBITION IN GLIOMAS
المؤلفون: Sabine Mueller, Karen Wright, Adam C. Resnick, Angela J. Waanders, Xiaodong Yang, Jie Zhang, William A. Weiss, Daphne A. Haas-Kogan, Rogier Dik, Kevin X. Liu
المصدر: Neuro-Oncology. 21:ii121-ii121
مصطلحات موضوعية: Cancer Research, Chemistry, mTORC1, medicine.disease, 3T3 cells, Blockade, medicine.anatomical_structure, Oncology, Cell culture, Glioma, Selumetinib, medicine, Cancer research, Neurology (clinical), Signal transduction, Translational Therapeutics, PI3K/AKT/mTOR pathway
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfca211ece625b4a445a0b240d99f3ef
https://doi.org/10.1093/neuonc/noz036.238 -
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المؤلفون: Xiaodong Yang, William A Weiss, Steven G. DuBois, Rogier Dik, Sabine Mueller, Kevin X. Liu, Adam C. Resnick, Angela J. Waanders, Daphne A. Haas-Kogan
المصدر: Neuro-Oncology. 19:vi85-vi86
مصطلحات موضوعية: Cancer Research, business.industry, Chemistry, medicine.disease, In vitro, Abstracts, Text mining, Oncology, In vivo, Glioma, medicine, Cancer research, Neurology (clinical), business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a54fe1968f8a94f7eec454455bd6dbb
https://doi.org/10.1093/neuonc/nox168.350 -
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المؤلفون: Rogier Dik, Xiaodong Yang, Ola Aleksandra, Angela J. Waanders, William A. Weiss, Steve DuBois, Clay Gustafson, Sabine Mueller, Daphne A. Haas-Kogan, Adam C. Resnick
مصطلحات موضوعية: Cancer Research, Everolimus, Kinase, Cell growth, mTORC1, Biology, Pharmacology, medicine.disease, mTORC2, Oncology, Cell culture, In vivo, Glioma, medicine, Cancer research, Neurology (clinical), neoplasms, Abstracts from the 3rd Biennial Conference on Pediatric Neuro-Oncology Basic and Translational Research, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9157d9c0e2c3adcb667879c7ef19061
https://europepmc.org/articles/PMC4483011/ -
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المؤلفون: Lukas J.A. Stalpers, Brigitta G. Baumert, Ben J. Slotman, Rogier Dik, Ravi S. Narayan, Peter Sminia, Jaap van den Berg
المصدر: Cancer Research. 74:4914-4914
مصطلحات موضوعية: MAPK/ERK pathway, Cancer Research, mTORC1, Biology, chemistry.chemical_compound, Oncology, chemistry, Cell culture, Radioresistance, Immunology, Cancer research, Growth inhibition, Clonogenic assay, Protein kinase B, PI3K/AKT/mTOR pathway
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::633da0bc14392affa6f52abbc6f3b012
https://doi.org/10.1158/1538-7445.am2014-4914