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1دورية أكاديمية
المؤلفون: Lalit K. Golani, Donna M. Platt, Daniela Rüedi-Bettschen, Chitra Edwanker, Shenming Huang, Michael M. Poe, Roman Furtmüller, Werner Sieghart, James M. Cook, James K. Rowlett
المصدر: Frontiers in Pharmacology, Vol 12 (2021)
مصطلحات موضوعية: benzodiazepine, anxiolytic, sedation, squirrel monkey, rhesus monkey, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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المؤلفون: Lalit K, Golani, Donna M, Platt, Daniela, Rüedi-Bettschen, Chitra, Edwanker, Shenming, Huang, Michael M, Poe, Roman, Furtmüller, Werner, Sieghart, James M, Cook, James K, Rowlett
المصدر: Frontiers in Pharmacology
مصطلحات موضوعية: Pharmacology, sedation, squirrel monkey, rhesus monkey, benzodiazepine, anxiolytic, Original Research
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::16ac88426fa324c29663b54412615b68
https://pubmed.ncbi.nlm.nih.gov/33959005 -
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المؤلفون: Terry Clayton, James M. Cook, Danni L. Harris, Peyman Sahbaie, Timothy M. DeLorey, Robert F. Halliwell, Werner Sieghart, Sigismund Huck, Roman Furtmüller
المصدر: Journal of Medicinal Chemistry. 51:3788-3803
مصطلحات موضوعية: Male, Models, Molecular, Gene isoform, Chemical Phenomena, Databases, Factual, Molecular model, Stereochemistry, medicine.drug_class, Quantitative Structure-Activity Relationship, Ligands, Benzodiazepines, Mice, Structure-Activity Relationship, Xenopus laevis, Memory, Drug Discovery, medicine, Animals, Protein Isoforms, Inverse agonist, Computer Simulation, Receptor, Binding selectivity, Benzodiazepine, Behavior, Animal, Molecular Structure, Chemistry, Physical, Ligand, GABAA receptor, Chemistry, Receptors, GABA-A, Electrophysiology, Protein Subunits, Oocytes, Molecular Medicine, Female
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المؤلفون: Lars Richter, Gerhard F. Ecker, Michael W. Parker, Catherine C. Kaczorowski, J. L. Chen, Margot Ernst, Brett A. Cromer, Werner Sieghart, F. J. Helmstetter, H.-L. Ng, Craig J. Morton, Roman Furtmüller, James M. Cook, Terrill Scott Clayton
المصدر: Current Medicinal Chemistry. 14:2755-2775
مصطلحات موضوعية: Pharmacology, Agonist, Molecular model, Ligand, GABAA receptor, medicine.drug_class, Chemistry, Stereochemistry, Organic Chemistry, Rational design, Biochemistry, Drug Discovery, medicine, Molecular Medicine, Binding site, Pharmacophore, Receptor
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المؤلفون: Terry Clayton, Werner Sieghart, James M. Cook, Roman Furtmüller, Nenad D. Ugrešić, Miroslav M. Savić, Sigismund Huck, Dubravko Bokonjić, Shengming Huang, Dragan I. Obradović
المصدر: Neuropsychopharmacology
مصطلحات موضوعية: Male, Agonist, medicine.medical_specialty, medicine.drug_class, Protein subunit, Subtype selectivity, Motor Activity, Pharmacology, GABAA-rho receptor, Benzodiazepines, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Animals, GABA(A), Rats, Wistar, Maze Learning, Receptor, 030304 developmental biology, Analysis of Variance, 0303 health sciences, Benzodiazepine, Chemistry, GABAA receptor, ataxia, anxiety, Receptors, GABA-A, subtype-selectivity, Rats, 3. Good health, Protein Subunits, Psychiatry and Mental health, Endocrinology, sedation, Sedative, benzodiazepine, 030217 neurology & neurosurgery
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المؤلفون: Roman Furtmüller, Ahmed El Hadri, Werner Sieghart, Roland Baur, Erwin Sigel, Robert H. Dodd, Urs Thomet, Ahmed Abouabdellah
المصدر: Journal of Medicinal Chemistry. 45:2824-2831
مصطلحات موضوعية: Patch-Clamp Techniques, Stereochemistry, Allosteric regulation, Loreclezole, Stimulation, In Vitro Techniques, Binding, Competitive, Chemical synthesis, Lactones, Radioligand Assay, Structure-Activity Relationship, Xenopus laevis, Allosteric Regulation, Electricity, Drug Discovery, medicine, Radioligand, Animals, Furans, Receptor, GABAA receptor, Chemistry, Brain, Stereoisomerism, Triazoles, Receptors, GABA-A, Recombinant Proteins, Rats, Mechanism of action, Oocytes, Molecular Medicine, Anticonvulsants, medicine.symptom, medicine.drug
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7
المؤلفون: M. G. Schlag, Werner Sieghart, Rudolf Hopf, Sigismund Huck, Michael L. Berger, Heinz Redl, Roman Furtmüller
المصدر: Journal of Pharmacology and Experimental Therapeutics. 301:168-173
مصطلحات موضوعية: Male, Agonist, Patch-Clamp Techniques, medicine.drug_class, Central nervous system, Pharmacology, Binding, Competitive, Receptors, N-Methyl-D-Aspartate, Cell Line, Membrane Potentials, GABA Antagonists, chemistry.chemical_compound, Seizures, Antifibrinolytic agent, medicine, Animals, Humans, GABA-A Receptor Antagonists, Patch clamp, Receptor, GABA Agonists, Brain Chemistry, Membrane potential, Membranes, Dose-Response Relationship, Drug, Muscimol, GABA receptor antagonist, Antifibrinolytic Agents, Hindlimb, Rats, medicine.anatomical_structure, Spinal Cord, Tranexamic Acid, chemistry, Molecular Medicine, Dizocilpine Maleate
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96ca4890f99fd28a1b9c3e49f893a96f
https://doi.org/10.1124/jpet.301.1.168 -
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المؤلفون: Frantisek Jursky, Werner Sieghart, Roman Furtmüller, Erwin Sigel, Urs Thomet, Robert H. Dodd, Rodolphe Razet
المصدر: Bioorganic & Medicinal Chemistry Letters. 10:2579-2583
مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Allosteric regulation, Xenopus, Pharmaceutical Science, Bicuculline, Ligands, Biochemistry, GABAA-rho receptor, GABA Antagonists, Allosteric Regulation, Drug Discovery, medicine, Moiety, Receptor, Molecular Biology, biology, GABAA receptor, Chemistry, Organic Chemistry, GABA receptor antagonist, Receptors, GABA-A, biology.organism_classification, Molecular Medicine, medicine.drug
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المؤلفون: Rodolphe Razet, Roman Furtmüller, Roland Baur, Urs Thomet, Robert H. Dodd, Werner Sieghart, Erwin Sigel
المصدر: British Journal of Pharmacology. 131:843-850
مصطلحات موضوعية: Pharmacology, medicine.medical_specialty, Allosteric modulator, GABAA receptor, Allosteric regulation, Loreclezole, Biology, Bicuculline, Inhibitory postsynaptic potential, Endocrinology, ROD-188, Internal medicine, medicine, Biophysics, GABA Modulators, medicine.drug
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المؤلفون: Patrice Venault, Jean-François Rousseau, Robert H. Dodd, Erwin Sigel, Georges Chapouthier, Roman Furtmüller, Werner Sieghart, Mireille Le Hyaric-Almeida, Urs Thomet
المصدر: Neuroscience Letters. 269:63-66
مصطلحات موضوعية: Flumazenil, Male, Pyridines, medicine.drug_class, Allosteric regulation, In Vitro Techniques, Ligands, Mice, Radioligand Assay, Xenopus laevis, chemistry.chemical_compound, Prosencephalon, Allosteric Regulation, Seizures, Cerebellum, DMCM, medicine, Animals, GABA Modulators, Receptor, Benzodiazepine, Binding Sites, GABAA receptor, General Neuroscience, Receptors, GABA-A, Ligand (biochemistry), Recombinant Proteins, Rats, chemistry, Biochemistry, Oocytes, Biophysics, Flunitrazepam, medicine.drug