المؤلفون: Sobottka, Bettina ¹, Nowak, Marta ¹, Frei, Anja Laura ¹, Haberecker, Martina ¹, Merki, Samuel ¹, Levesque, Mitchell P. ², Dummer, Reinhard ², Moch, Holger ¹, Koelzer, Viktor Hendrik ¹, Aebersold, Rudolf ³, Ak, Melike ⁴, Al-Quaddoomi, Faisal S. ^{5, 6}, Albinus, Jonas ⁷, Alborelli, Ilaria ⁸, Andani, Sonali ^{6, 9, 10, 11}, Attinger, Per-Olof ¹², Bacac, Marina ¹³, Baumhoer, Daniel ⁸, Beck-Schimmer, Beatrice ¹⁴, Beerenwinkel, Niko ^{6, 15}, Beisel, Christian ¹⁵, Bernasconi, Lara ¹⁶, Bertolini, Anne ^{5, 6}, Bodenmiller, Bernd ^{17, 18}, Bonilla, Ximena ^{6, 9, 10}, Casanova, Ruben ¹⁸, Chevrier, Stéphane ¹⁸, Chicherova, Natalia ^{5, 6}, D'Costa, Maya ¹², Danenberg, Esther ¹⁹, Davidson, Natalie ^{6, 9, 10}, Drăganmoch, Monica-Andreea ¹⁵, Engler, Stefanie ¹⁸, Erkens, Martin ²⁰, Eschbach, Katja ¹⁵, Esposito, Cinzia ¹⁹, Fedier, André ²¹, Ferreira, Pedro ¹⁵, Ficek, Joanna ^{6, 9, 10}, Frey, Bruno ²², Goetze, Sandra ⁷, Grob, Linda ^{5, 6}, Gut, Gabriele ¹⁹, Günther, Detlef ²³, Haeuptle, Pirmin ²⁴, Heinzelmann-Schwarz, Viola ^{21, 25}, Herter, Sylvia ¹³, Holtackers, Rene ¹⁹, Huesser, Tamara ¹³, Irmisch, Anja ⁴, Jacob, Francis ²¹, Jacobs, Andrea ¹⁸, Jaeger, Tim M. ¹², Jahn, Katharina ¹⁵, James, Alva R. ^{6, 9, 10}, Jermann, Philip M. ⁸, Kahles, André ^{6, 9, 10}, Kahraman, Abdullah ^{6, 11}, Kuebler, Werner ²⁶, Kuipers, Jack ^{6, 15}, Kunze, Christian P. ²⁷, Kurzeder, Christian ²⁸, Lehmann, Kjong-Van ^{6, 9, 10}, Lugert, Sebastian ¹², Maass, Gerd ²², Manz, Markus G. ²⁹, Markolin, Philipp ^{6, 9, 10}, Mena, Julien ³, Menzel, Ulrike ¹⁵, Metzler, Julian M. ³⁰, Miglino, Nicola ²⁴, Milani, Emanuela S. ⁷, Muenst, Simone ⁸, Murri, Riccardo ³¹, Ng, Charlotte K.Y. ^{8, 32}, Nicolet, Stefan ⁸, Pedrioli, Patrick G.A. ³³, Pelkmans, Lucas ¹⁹, Piscuoglio, Salvatore ^{8, 21}, Prummer, Michael ^{5, 6}, Ritter, Mathilde ²¹, Rommel, Christian ²⁰, Rosano-González, María L. ^{5, 6}, Rätsch, Gunnar ^{6, 9, 10, 33}, Santacroce, Natascha ¹⁵, del Castillo, Jacobo Sarabia ¹⁹, Schlenker, Ramona ³⁴, Schwalie, Petra C. ²⁰, Schwan, Severin ¹², Schär, Tobias ¹⁵, Senti, Gabriela ¹⁶, Singer, Franziska ^{5, 6}, Sivapatham, Sujana ¹⁸, Snijder, Berend ^{3, 6}, Sreedharan, Vipin T. ^{5, 6}, Stark, Stefan ^{6, 9, 10}, Stekhoven, Daniel J. ^{5, 6}, Theocharides, Alexandre P.A. ²⁹, Thomas, Tinu M. ^{6, 9, 10}, Tolnay, Markus ⁸, Tosevski, Vinko ¹³, Toussaint, Nora C. ^{5, 6}, Tuncel, Mustafa A. ^{6, 15}, Tusup, Marina ⁴, Van Drogen, Audrey ⁷, Vetter, Marcus ³⁵, Vlajnic, Tatjana ⁸, Weber, Sandra ¹⁶, Weber, Walter P. ³⁶, Wegmann, Rebekka ³, Weller, Michael ³⁷, Wendt, Fabian ⁷, Wey, Norbert ¹¹, Wicki, Andreas ^{29, 38}, Wildschut, Mattheus HE ^{3, 29}, Wollscheid, Bernd ⁷, Yu, Shuqing ^{5, 6}, Ziegler, Johanna ⁴, Zimmermann, Marc ^{6, 9, 10}, Zoche, Martin ¹¹, Zuend, Gregor ³⁹

المصدر: In Laboratory Investigation December 2021 101(12):1561-1570

المؤلفون: Zeng, Zhihong, Wang, Rui-Yu, Qiu, Yi Hua, Mak, Duncan H, Coombes, Kevin, Yoo, Suk Young, Zhang, Qi, Jessen, Katti, Liu, Yi, Rommel, Christian, Fruman, David A, Kantarjian, Hagop M, Kornblau, Steven M, Andreeff, Michael, Konopleva, Marina

المصدر: Oncotarget. 7(34)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Hematology, Pediatric Research Initiative, Stem Cell Research, Stem Cell Research - Nonembryonic - Human, Stem Cell Research - Nonembryonic - Non-Human, Pediatric, Cancer, Pediatric Cancer, Childhood Leukemia, Rare Diseases, Acute Disease, Animals, Apoptosis, Benzoxazoles, Cell Line, Tumor, Cell Proliferation, Cell Survival, Humans, Leukemia, Myeloid, Mice, Inbred NOD, Mice, Knockout, Mice, SCID, Neoplastic Stem Cells, Phosphorylation, Proto-Oncogene Proteins c-akt, Pyrimidines, Signal Transduction, TOR Serine-Threonine Kinases, U937 Cells, Xenograft Model Antitumor Assays, mTOR, AML, stem cells, CyTOF, therapy, Oncology and carcinogenesis

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6w11w157

المؤلفون: Fruman, David A, Rommel, Christian

المصدر: Nature Reviews Drug Discovery. 13(2)

مصطلحات موضوعية: Cancer, Rare Diseases, Animals, Antineoplastic Agents, Clinical Trials as Topic, Drug Discovery, Enzyme Inhibitors, Humans, Neoplasms, Phosphoinositide-3 Kinase Inhibitors, Proto-Oncogene Proteins c-akt, Receptor Cross-Talk, Signal Transduction, TOR Serine-Threonine Kinases, Biological Sciences, Medical and Health Sciences, Pharmacology & Pharmacy

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7mh5z8hb

المؤلفون: So, Lomon, Yea, Sung Su, Oak, Jean S., Lu, Mengrou, Manmadhan, Arun, Ke, Qiao Han, Janes, Matthew R., Kessler, Linda V., Kucharski, Jeff M., Li, Lian-Sheng, Martin, Michael B., Ren, Pingda, Jessen, Katti A., Liu, Yi, Rommel, Christian, Fruman, David A.

المصدر: The Journal of Biological Chemistry. 288(8)

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6cp6h44b

المؤلفون: Janes, Matthew R., Vu, Collin, Mallya, Sharmila, Shieh, Marie, Limon, Jose J., Li, Lian-Sheng, Jessen, Katti A., Martin, Michael B., Ren, Pingda, Lilly, Michael B., Sender, Leonard, Liu, Yi, Rommel, Christian, Fruman, David A.

المصدر: Leukemia. 27(3)

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6wj4c6f6

المؤلفون: Berndt, Alex, Miller, Simon, Williams, Olusegun, Le, Daniel D, Houseman, Benjamin T, Pacold, Joseph I, Gorrec, Fabrice, Hon, Wai-Ching, Ren, Pingda, Liu, Yi, Rommel, Christian, Gaillard, Pascale, Rückle, Thomas, Schwarz, Matthias K, Shokat, Kevan M, Shaw, Jeffrey P, Williams, Roger L

المصدر: Nature Chemical Biology. 6(2)

مصطلحات موضوعية: Biochemistry and Cell Biology, Chemical Sciences, Biological Sciences, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Adenosine Triphosphate, Animals, Catalytic Domain, Cell Line, Computer Simulation, Crystallography, X-Ray, Humans, Hydrophobic and Hydrophilic Interactions, Models, Molecular, Phosphatidylinositol 3-Kinases, Protein Interaction Domains and Motifs, Protein Kinase Inhibitors, Spodoptera, Structure-Activity Relationship, Substrate Specificity, Medicinal and Biomolecular Chemistry, Biochemistry & Molecular Biology, Biochemistry and cell biology, Medicinal and biomolecular chemistry

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5kp6f1w5

المؤلفون: Berndt, Alex, Miller, Simon, Williams, Olusegun, Le, Daniel D, Houseman, Benjamin T, Pacold, Joseph I, Gorrec, Fabrice, Hon, Wai-Ching, Liu, Yi, Rommel, Christian, Gaillard, Pascale, Rückle, Thomas, Schwarz, Matthias K, Shokat, Kevan M, Shaw, Jeffrey P, Williams, Roger L

المصدر: Nature chemical biology. 6(2)

مصطلحات موضوعية: Cell Line, Animals, Humans, Spodoptera, Adenosine Triphosphate, Protein Kinase Inhibitors, Crystallography, X-Ray, Catalytic Domain, Structure-Activity Relationship, Substrate Specificity, Models, Molecular, Computer Simulation, Protein Interaction Domains and Motifs, Phosphatidylinositol 3-Kinases, Hydrophobic and Hydrophilic Interactions, Crystallography, X-Ray, Models, Molecular, Medicinal and Biomolecular Chemistry, Biochemistry and Cell Biology, Biochemistry & Molecular Biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5kp6f1w5

المؤلفون: Rommel, Christian, Clarke, Brian A., Zimmermann, Sven, Nuñez, Lorna, Rossman, Roni, Reid, Kristina, Moelling, Karin, Yancopoulos, George D., Glass, David J.

المصدر: Science, 1999 Nov . 286(5445), 1738-1741.

URL الوصول: https://www.jstor.org/stable/2900101

المؤلفون: Vanhaesebroeck, Bart^Aff1_65, Vogt, Peter K.^Aff2_65, Rommel, Christian^Aff3_65

المساهمون: Rommel, Christian, editor^AffID1, Vanhaesebroeck, Bart, editor^AffID2, Vogt, Peter K., editor^AffID3

المصدر: Phosphoinositide 3-kinase in Health and Disease : Volume 2. 347:1-19

المؤلفون: Rommel, Christian^Aff1_79

المساهمون: Rommel, Christian, editor^AffID1, Vanhaesebroeck, Bart, editor^AffID2, Vogt, Peter K., editor^AffID3

المصدر: Phosphoinositide 3-kinase in Health and Disease : Volume 1. 346:279-299