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المؤلفون: Ronan P. Hanley, David Y. Nie, John R. Tabor, Fengling Li, Amin Sobh, Chenxi Xu, Natalie K. Barker, David Dilworth, Taraneh Hajian, Elisa Gibson, Magdalena M. Szewczyk, Peter J. Brown, Dalia Barsyte-Lovejoy, Laura E. Herring, Gang Greg Wang, Jonathan D. Licht, Masoud Vedadi, Cheryl H. Arrowsmith, Lindsey I. James
المصدر: Journal of the American Chemical Society. 145:8176-8188
مصطلحات موضوعية: Colloid and Surface Chemistry, General Chemistry, Biochemistry, Catalysis
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المؤلفون: Frances M. Bashore, Caroline A. Foley, Han Wee Ong, Justin M. Rectenwald, Ronan P. Hanley, Jacqueline L. Norris-Drouin, Stephanie H. Cholensky, Christine A. Mills, Kenneth H. Pearce, Laura E. Herring, Dmitri Kireev, Stephen V. Frye, Lindsey I. James
المصدر: ACS Chemical Biology. 18:494-507
مصطلحات موضوعية: Molecular Medicine, General Medicine, Biochemistry
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المؤلفون: Marcus A. Cheek, Aiping Dong, Renato Ferreira de Freitas, Dalia Barsyte-Lovejoy, Aliakbar Khalili Yazdi, Jinrong Min, Fengling Li, Victoria Vu, Albina Bolotokova, Lindsey I. James, Jack Greenblatt, Naimee Mehta, Irina K. Popova, David Dilworth, Ming Lei, Raquel Arminda Carvalho Machado, Ronan P Hanley, David Y Nie, Matthieu Schapira, Mengqi Zhou, Elisa Gibson, Cheryl H. Arrowsmith, Michael-Christopher Keogh, Suzanne Ackloo, Matthew R. Marunde, Mona Alqazzaz, Dmitri Kireev, Nathan W. Hall, Peter Brown, Abdellah Allali-Hassani, Sina Kazemzadeh, Edyta Marcon, Tigran M. Abramyan, Dominic D G Owens, Yanli Liu, Magdalena M. Szewczyk, Matthew J. Meiners, Irene Chau, Su Qin, Masoud Vedadi
المصدر: Nat Chem Biol
مصطلحات موضوعية: Gene isoform, Methyltransferase, Nucleolus, Lysine, Methylation, Article, 03 medical and health sciences, 0302 clinical medicine, Protein Domains, Molecular Biology, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, biology, Chemistry, Histone-Lysine N-Methyltransferase, Cell Biology, Nucleosomes, Chromatin, Cell biology, Repressor Proteins, Histone, Enzyme, Molecular Probes, 030220 oncology & carcinogenesis, biology.protein, Multiple Myeloma, Cell Nucleolus
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المؤلفون: Jinrong Min, Matthew R. Marunde, Dmitri Kireev, Jack Greenblatt, Ferreira de Freitas R, Tigran M. Abramyan, Cheryl H. Arrowsmith, Peter Brown, Magda Szewczyk, Irene Chau, A. Dong, Kazemzadeh S, Dalia Barsyte-Lovejoy, Ronan P Hanley, Mengqi Zhou, Y. Liu, Michael-Christopher Keogh, Lindsey I. James, Edyta Marcon, Matthieu Schapira, David Dilworth, Ming Lei, Popova Ik, Albina Bolotokova, Marcus A. Cheek, Masoud Vedadi, Elisa Gibson, Suzanne Ackloo, Su Qin, Matthew J. Meiners, Nathan W. Hall, Abdellah Allali-Hassani, Naimee Mehta, Fengling Li
مصطلحات موضوعية: Gene isoform, Mutation, Methyltransferase, biology, Nucleolus, Chemistry, Methylation, medicine.disease_cause, Subcellular localization, Cell biology, Chromatin, Histone, medicine, biology.protein
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9e4c6ef23b32f1b09d83b9d0588c0ec9
https://doi.org/10.1101/2021.03.05.433782 -
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المؤلفون: Derek J Blevins, Fraser Hof, Trevor Bolduc, David A. Powell, Ronan P. Hanley, Michael C. Gignac, Mark D. Carr, Jeremy E. Wulff, Kayleigh Walker
المصدر: ACS Med Chem Lett
مصطلحات موضوعية: biology, 010405 organic chemistry, Chemistry, Peptidomimetic, Organic Chemistry, Ligand (biochemistry), 01 natural sciences, Biochemistry, Small molecule, In vitro, 0104 chemical sciences, Cell biology, 010404 medicinal & biomolecular chemistry, Protein sequencing, PD-L1, Drug Discovery, biology.protein, Splenocyte, Mode of action
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المؤلفون: Dalia Barsyte-Lovejoy, Masoud Vedadi, Cheryl H. Arrowsmith, Jinrong Min, Ronan P Hanley, Rima Al-awar, Matthieu Schapira, Lindsey I. James, Renato Ferreira de Freitas, Magdalena M. Szewczyk, Abdellah Allali-Hassani, Naimee Mehta, Fengling Li, Carlos Zepeda-Velázquez, Elisa Gibson, David McLeod, Yanli Liu, Peter Brown, David Dilworth
المصدر: J Med Chem
مصطلحات موضوعية: Models, Molecular, Methyltransferase, Protein domain, Drug Evaluation, Preclinical, Antineoplastic Agents, Crystallography, X-Ray, Ligands, 01 natural sciences, Article, Small Molecule Libraries, 03 medical and health sciences, Structure-Activity Relationship, Protein Domains, Drug Discovery, Structure–activity relationship, Humans, Computer Simulation, 030304 developmental biology, 0303 health sciences, Virtual screening, biology, Chemistry, Antagonist, Histone-Lysine N-Methyltransferase, Small molecule, 0104 chemical sciences, 3. Good health, Cell biology, Molecular Docking Simulation, Repressor Proteins, 010404 medicinal & biomolecular chemistry, Histone, biology.protein, Molecular Medicine, Drug Screening Assays, Antitumor
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المؤلفون: Jeremy E. Wulff, Shanti Horvath, Fraser Hof, Ronan P. Hanley, Jianghong An
المصدر: Bioorganic & Medicinal Chemistry Letters. 26:973-977
مصطلحات موضوعية: 0301 basic medicine, Stereochemistry, Programmed Cell Death 1 Receptor, Clinical Biochemistry, Pharmaceutical Science, Context (language use), Biochemistry, Small Molecule Libraries, 03 medical and health sciences, Europium, Ethers, Cyclic, Drug Discovery, High-Throughput Screening Assays, Fluorescence Resonance Energy Transfer, False positive paradox, Molecular Biology, Schiff Bases, Binding Sites, Drug discovery, Chemistry, Organic Chemistry, Surface Plasmon Resonance, Salicylates, Protein Structure, Tertiary, 3. Good health, Molecular Docking Simulation, 030104 developmental biology, Förster resonance energy transfer, Molecular Medicine
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المؤلفون: Ronan P. Hanley, Natasha F. O’Rourke, Anna R. Patten, Brian R. Christie, Ana Lúcia S. Rodrigues, Jeremy E. Wulff, Karthik Gopalakrishnan, Luis E.B. Bettio, Samantha Kennedy, Joana Gil-Mohapel
المصدر: Neuroscience. 332
مصطلحات موضوعية: 0301 basic medicine, Mef2, Male, Neurogenesis, Drug Evaluation, Preclinical, Hippocampus, Beta-Cyclodextrins, Thiophenes, Hippocampal formation, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, Animals, Cell Proliferation, Neurons, Molecular Structure, Cell growth, General Neuroscience, Dentate gyrus, beta-Cyclodextrins, Isoxazoles, Immunohistochemistry, 3. Good health, 2-Hydroxypropyl-beta-cyclodextrin, 030104 developmental biology, Dentate Gyrus, Stem cell, Psychology, Corticosterone, Neuroscience, 030217 neurology & neurosurgery, Stress, Psychological, Central Nervous System Agents