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1دورية أكاديمية
المؤلفون: Dan Xia, Steve Lianoglou, Thomas Sandmann, Meredith Calvert, Jung H. Suh, Elliot Thomsen, Jason Dugas, Michelle E. Pizzo, Sarah L. DeVos, Timothy K. Earr, Chia-Ching Lin, Sonnet Davis, Connie Ha, Amy Wing-Sze Leung, Hoang Nguyen, Roni Chau, Ernie Yulyaningsih, Isabel Lopez, Hilda Solanoy, Shababa T. Masoud, Chun-chi Liang, Karin Lin, Giuseppe Astarita, Nathalie Khoury, Joy Yu Zuchero, Robert G. Thorne, Kevin Shen, Stephanie Miller, Jorge J. Palop, Dylan Garceau, Michael Sasner, Jennifer D. Whitesell, Julie A. Harris, Selina Hummel, Johannes Gnörich, Karin Wind, Lea Kunze, Artem Zatcepin, Matthias Brendel, Michael Willem, Christian Haass, Daniel Barnett, Till S. Zimmer, Anna G. Orr, Kimberly Scearce-Levie, Joseph W. Lewcock, Gilbert Di Paolo, Pascal E. Sanchez
المصدر: Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-29 (2022)
مصطلحات موضوعية: Neuritic plaques, Vascular amyloid, Neurodegeneration, Astrogliosis, Phagocytic microglia, Lipid dyshomeostasis, Neurology. Diseases of the nervous system, RC346-429, Geriatrics, RC952-954.6
وصف الملف: electronic resource
Relation: https://doaj.org/toc/1750-1326
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المؤلفون: Robert A. Craig, Brian M. Fox, Cheng Hu, Katrina W. Lexa, Maksim Osipov, Arun P. Thottumkara, Martin Larhammar, Takashi Miyamoto, Anil Rana, Lesley A. Kane, Ernie Yulyaningsih, Hilda Solanoy, Hoang Nguyen, Roni Chau, Timothy Earr, Yuji Kajiwara, Daniel Fleck, Anthony Lucas, Patrick C. G. Haddick, Ryan H. Takahashi, Vincent Tong, Jing Wang, Mark J. Canet, Suresh B. Poda, Kimberly Scearce-Levie, Ankita Srivastava, Zachary K. Sweeney, Musheng Xu, Rui Zhang, Jianrong He, Yanan Lei, Zheng Zhuo, Javier de Vicente
المصدر: Journal of Medicinal Chemistry. 65:16290-16312
مصطلحات موضوعية: Central Nervous System, Leucine Zippers, Amyotrophic Lateral Sclerosis, Drug Discovery, Humans, Brain, Molecular Medicine, Neurodegenerative Diseases, MAP Kinase Kinase Kinases
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3Molecular architecture determines brain delivery of a transferrin receptor–targeted lysosomal enzyme
المؤلفون: Annie Arguello, Cathal S. Mahon, Meredith E.K. Calvert, Darren Chan, Jason C. Dugas, Michelle E. Pizzo, Elliot R. Thomsen, Roni Chau, Lorna A. Damo, Joseph Duque, Meng Fang, Tina Giese, Do Jin Kim, Nicholas Liang, Hoang N. Nguyen, Hilda Solanoy, Buyankhishig Tsogtbaatar, Julie C. Ullman, Junhua Wang, Mark S. Dennis, Dolores Diaz, Kannan Gunasekaran, Kirk R. Henne, Joseph W. Lewcock, Pascal E. Sanchez, Matthew D. Troyer, Jeffrey M. Harris, Kimberly Scearce-Levie, Lu Shan, Ryan J. Watts, Robert G. Thorne, Anastasia G. Henry, Mihalis S. Kariolis
المصدر: Journal of Experimental Medicine. 219
مصطلحات موضوعية: Recombinant Fusion Proteins, Immunology, Brain, Endothelial Cells, Iduronate Sulfatase, Disease Models, Animal, Mice, Blood-Brain Barrier, Receptors, Transferrin, Animals, Immunology and Allergy, Tissue Distribution, Lysosomes, Mucopolysaccharidosis II
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7f8502d8d835baeb28ac3730bfbbf0e
https://doi.org/10.1084/jem.20211057 -
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المؤلفون: Ryan J. Watts, Kathryn M. Monroe, Junhua Wang, Melina Lenser, Jennifer Hsiao-Nakamoto, Hoang Nguyen, Todd P. Logan, Do Jin Kim, Fen Huang, Ritesh Ravi, Gilbert Di Paolo, Anil Rana, Kannan Gunasekaran, Yaneth Robles-Colmenares, Gerald M. Cherf, Buyankhishig Tsogtbaatar, Ceyda Llapashtica, Kirk R. Henne, Hilda Solanoy, Pascal E. Sanchez, Yashas Rajendra, Mihalis Kariolis, Ray Lieh Yoon Low, Roni Chau, Laralynne Przybyla, Michelle E. Pizzo, Chi-Lu Chiu, Meng Fang, Anastasia G. Henry, Giuseppe Astarita, Mark S. Dennis, Adam L. Boxer, Sarah L. DeVos, Sonnet S. Davis, Hilary W. Heuer, René Meisner, Joseph W. Lewcock, Devendra B. Srivastava, Bradley F. Boeve, Meredith E. K. Calvert, Katrina W. Lexa, Rachel Prorok, Lukas L. Skuja, Dolores Diaz, Akhil Bhalla, Matthew Simon, Jung H. Suh, Ankita Srivastava, Timothy K. Earr, Howard J. Rosen, Joseph Duque, Bettina Van Lengerich, Elizabeth W. Sun
المصدر: Cell
Cell, vol 184, iss 18مصطلحات موضوعية: Male, Neurodegenerative, Inbred C57BL, medicine.disease_cause, Medical and Health Sciences, Transgenic, Mice, neurodegenerative disease, Progranulins, Immunologic, Receptors, 2.1 Biological and endogenous factors, Tissue Distribution, Gliosis, Aetiology, Receptors, Immunologic, lipofuscin, Alzheimer's Disease Related Dementias (ADRD), Membrane Glycoproteins, Microglia, Transferrin, Brain, Biological Sciences, metabolomics, Cell biology, Frontotemporal Dementia (FTD), medicine.anatomical_structure, Phenotype, Galectin-3, Frontotemporal Dementia, Neurological, Bone Morphogenetic Proteins, lysosome, GBA, Female, LBPA, Induced Pluripotent Stem Cells, Transferrin receptor, Mice, Transgenic, Endosomes, Biology, General Biochemistry, Genetics and Molecular Biology, Article, Lipofuscin, lipids, Rare Diseases, Lysosome, galectin-3, Receptors, Transferrin, Acquired Cognitive Impairment, medicine, Animals, Humans, Loss function, Inflammation, Biological Products, Macrophages, Neurosciences, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Lipid Metabolism, Brain Disorders, Lysosomal Storage Diseases, Mice, Inbred C57BL, Nerve Degeneration, lipidomics, Dementia, lysobisphosphatidic acid, Lysosomes, Glucocerebrosidase, Oxidative stress, Developmental Biology
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6e8760616b55660b5a69ea73b7ad6da
https://europepmc.org/articles/PMC8489356/ -
5Molecular architecture determines brain delivery of a transferrin-receptor targeted lysosomal enzyme
المؤلفون: Kirk R. Henne, Kimberly Scearce-Levie, Annie Arguello, Ullman Julie, Mihalis Kariolis, Tina Giese, Jeffrey M. Harris, Matthew D. Troyer, Kannan Gunasekaran, Meredith E. K. Calvert, Dolores Diaz, Anastasia G. Henry, Elliot R. Thomsen, Buyankhishig Tsogtbaatar, Roni Chau, Isabel Lopez, Joseph W. Lewcock, Cathal Mahon, Michelle E. Pizzo, Lu Shan, Darren Chan, Meng Fang, Pascal E. Sanchez, Robert G. Thorne, Timothy K. Earr, Ryan J. Watts, Joseph Duque, Lorna A. Damo, Mark S. Dennis, Hoang N. Nguyen, Do Jin Kim, Junhua Wang, Nicholas Liang, Hilda Solanoy, Jason C. Dugas
مصطلحات موضوعية: chemistry.chemical_classification, Biodistribution, medicine.drug_class, media_common.quotation_subject, Transferrin receptor, Monoclonal antibody, Cell biology, Endothelial stem cell, Transcytosis, chemistry, Transferrin, medicine, Mucopolysaccharidosis type II, Internalization, media_common
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3ae90ba1655eaabdb89b5f77c6a55a6f
https://doi.org/10.1101/2021.05.21.445035 -
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المؤلفون: Dylan Garceau, Jennifer D. Whitesell, Julie A. Harris, Hilda Solanoy, Hoang Nguyen, Gilbert Di Paolo, Connie W.Y. Ha, Robert G. Thorne, Meredith E. K. Calvert, Joseph W. Lewcock, Karin Lin, Roni Chau, Thomas Sandmann, Sarah L. DeVos, Steve Lianoglou, Michael Sasner, Michelle E. Pizzo, Richard H. Liang, Jason C. Dugas, Jung H. Suh, Elliot R. Thomsen, Timothy K. Earr, Chia-Ching Lin, Kimberly Scearce-Levie, Dan Xia, Sonnet S. Davis, Shababa T. Masoud, Pascal E. Sanchez, Ernie Yulyaningsih
مصطلحات موضوعية: Pathogenesis, Transcriptome, medicine.anatomical_structure, Lipid accumulation, Microglia, Parenchyma, Neurodegeneration, medicine, Knock in mouse, Biology, medicine.disease, Vascular amyloid, Cell biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::740621cd30fb1a8feec1aa4ace66f9b6
https://doi.org/10.1101/2021.01.19.426731 -
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المؤلفون: Hoang Nguyen, Elizabeth Sun, Yashas Rajendra, Gerald Maxwell Cherf, Jennifer Hsiao-Nakamoto, Todd P. Logan, Joseph Duque, Anil Rana, Fen Huang, Matthew J. Simon, Kannan Gunasekaran, Pascal E. Sanchez, Junhua Wang, Mihalis Kariolis, Kirk R. Henne, Zachary Kevin Sweeney, Sofia Mosesova, Sonnet S. Davis, Bettina Van Lengerich, Do Jin Kim, Hai L. Tran, Rachel Prorok, Darren Chan, Mark S. Dennis, Kathryn M. Monroe, Yuda Zhu, Ray Low, Akhil Bhalla, Gilbert Di Paolo, Ankita Srivastava, Giuseppe Astarita, Timothy K. Earr, Joseph W. Lewcock, Roni Chau, Sarah L. DeVos, Ryan J. Watts, Melina Lenser
المصدر: Alzheimer's & Dementia. 16
مصطلحات موضوعية: Epidemiology, Health Policy, Biology, Phenotype, Cell biology, Psychiatry and Mental health, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Developmental Neuroscience, chemistry, Knockout mouse, Neurology (clinical), Geriatrics and Gerontology, Penetrant (biochemical)
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المؤلفون: Roni Chau, Jock S. Hamilton, Giancarlo Gutierrez Ibanez, Barbara A Horwitz, John M. Horowitz
المصدر: The FASEB Journal. 26
مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Genetics, Hippocampus, Hamster, Pharmacology, Augment, Molecular Biology, Biochemistry, Neuroprotection, Histamine, Biotechnology