المؤلفون: Carlos Montero, Lorna Hayhurst, Leslie Walton, Stephen N. Mitchell, Rosemarie Tomlinson, Louise Wallace, Graham Henry Timms, Jeremy Gilmore, Jeremy Findlay, Jane Cooper, John R. Boot, Richard J. Broadmore, Alicia Marcos, Ana B. Bueno

المصدر: Bioorganic & Medicinal Chemistry Letters. 17:3344-3348

مصطلحات موضوعية: Stereochemistry, Serotonin reuptake inhibitor, Guinea Pigs, Clinical Biochemistry, Pharmaceutical Science, Naphthalenes, Pharmacology, Biochemistry, Piperazines, Structure-Activity Relationship, Drug Discovery, Animals, Structure–activity relationship, Serotonin Antagonists, Serotonin Uptake Inhibitors, Receptor, Molecular Biology, 5-HT receptor, Dose-Response Relationship, Drug, Chemistry, Organic Chemistry, Antagonist, Stereoisomerism, Antidepressive Agents, Kinetics, Models, Chemical, Receptor, Serotonin, 5-HT1D, Molecular Medicine, Reuptake inhibitor, Selective Serotonin Reuptake Inhibitors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3734ec8a04967e83fa4406254d9354a9
https://doi.org/10.1016/j.bmcl.2007.03.101

المؤلفون: Bryan G. Johnson, Joseph P. Tizzano, Michael P. Johnson, Kelly I. Griffey, Darryle D. Schoepp, Rebecca A. Wright, John R. Harris, Gerald Kelly, Ann E. Kingston, Mary Jo Chamberlain, Rosemarie Tomlinson, Barry Peter Clark, Richard S. Baker

المصدر: Neuroscience Letters. 330:127-130

مصطلحات موضوعية: Agonist, medicine.drug_class, Glycine, Thiophenes, Pharmacology, Receptors, Metabotropic Glutamate, Benzoates, Hippocampus, Rats, Sprague-Dawley, Inhibitory Concentration 50, Mice, Structure-Activity Relationship, Seizures, In vivo, Cerebellum, Excitatory Amino Acid Agonists, medicine, Animals, Drug Interactions, Receptor, Alanine, Dose-Response Relationship, Drug, Chemistry, General Neuroscience, Antagonist, Glutamate receptor, Resorcinols, Rats, Metabotropic receptor, Xanthenes, Metabotropic glutamate receptor 1, Propionates, Pharmacophore, Excitatory Amino Acid Antagonists

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1cbdd09122fcc04534fbba2a2c6b34a
https://doi.org/10.1016/s0304-3940(02)00751-6

المؤلفون: John R. Boot, Marlene L. Cohen, David L. Nelson, Kathryn W. Schenck, Ellen M. Colvin, Susan Wedley, Ian A. Pullar, Rosemarie Tomlinson, Virginia L. Lucaites, Stephen L. Carney, Conway Richard Gerard, Clare Hardy

المصدر: European Journal of Pharmacology. 432:9-17

مصطلحات موضوعية: Male, Pharmacology, Sulfur Radioisotopes, Mice, Norepinephrine, Receptor, Serotonin, 5-HT2B, Receptor, Serotonin, 5-HT2C, Receptor, Serotonin, 5-HT2A, Receptor, Cerebral Cortex, Serotonin Plasma Membrane Transport Proteins, Membrane Glycoproteins, Thiadiazines, Sumatriptan, Chemistry, Drug Synergism, Receptor antagonist, Cyclic S-Oxides, Serotonin Receptor Agonists, Receptor, Serotonin, 5-HT1D, Receptor, Serotonin, 5-HT1B, Autoreceptor, Rabbits, Serotonin Antagonists, medicine.symptom, Agonist, Serotonin, medicine.medical_specialty, medicine.drug_class, Nerve Tissue Proteins, In Vitro Techniques, Tritium, Binding, Competitive, Internal medicine, medicine, Animals, Humans, Saphenous Vein, 5-HT receptor, Dose-Response Relationship, Drug, Antagonist, Membrane Transport Proteins, Endocrinology, Mechanism of action, Guanosine 5'-O-(3-Thiotriphosphate), Vasoconstriction, Receptors, Serotonin, Potassium, Carrier Proteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7be58220027e0b6deadaac94f9eb815
https://doi.org/10.1016/s0014-2999(01)01468-6

المؤلفون: Marvin M. Hansen, Harkness Allen Robert, James A. Monn, Richard A. Lewis, Kress Thomas Joseph, James P. Wepsiec, Matthew John Valli, Darryle D. Schoepp, Joseph P. Tizzano, Ann E. Kingston, Rebecca A. Wright, John L. Grutsch, Kelly R. Griffey, Sherri L. Andis, Bryan G. Johnson, Rosemarie Tomlinson, Steven Marc Massey

المصدر: Journal of Medicinal Chemistry. 42:1027-1040

مصطلحات موضوعية: Models, Molecular, Agonist, Stereochemistry, medicine.drug_class, Kainate receptor, AMPA receptor, In Vitro Techniques, Receptors, Metabotropic Glutamate, Second Messenger Systems, Cell Line, Bridged Bicyclo Compounds, Mice, Seizures, Drug Discovery, Cyclic AMP, Excitatory Amino Acid Agonists, medicine, Animals, Humans, Amino Acids, Receptor, Chemistry, Brain, Stereoisomerism, Bridged Bicyclo Compounds, Heterocyclic, Receptor antagonist, Recombinant Proteins, Rats, Metabotropic receptor, Metabotropic glutamate receptor, Molecular Medicine, NMDA receptor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea93ca189e0b43ccac36b77c1bff6478
https://doi.org/10.1021/jm980616n

المؤلفون: Kelly A. Halliday, Smith Colin William, Rosemarie Tomlinson, W. Martin Owton, Michael Brunavs, David R. Dobson, Stephen L. Carney, Miles Martin Victor, Richard J. Broadmore, Samantha J. Ambler, Ann E. Kingston, David J. Steggles, Peter Thaddeus Gallagher, T. A. Hicks

المصدر: Bioorganic & Medicinal Chemistry Letters. 7:817-822

مصطلحات موضوعية: Chemistry, Glucose uptake, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Tumor cells, Osteoarthritis, Ehrlich ascites, medicine.disease, Biochemistry, In vitro, Chondrocyte, chemistry.chemical_compound, medicine.anatomical_structure, Mechanism of action, Drug Discovery, Anthraquinones, medicine, Molecular Medicine, medicine.symptom, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0c3b528cf07f09d355047545625fb3fe
https://doi.org/10.1016/s0960-894x(97)00102-9

المؤلفون: Louise Wallace, Javier Agejas, Alicia Torrado, Jeremy Findlay, Alma Jiménez, Nuria Diaz, Richard J. Broadmore, John R. Boot, Jeremy Gilmore, Rosemarie Tomlinson, Lorna Hayhurst, Carlos Lamas

المصدر: Bioorganicmedicinal chemistry. 12(20)

مصطلحات موضوعية: Bicyclic molecule, Chemistry, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Naphthylpiperazine, Antagonist, Pharmaceutical Science, Pharmacology, Serotonin 5-HT1 Receptor Antagonists, Biochemistry, Chemical synthesis, In vitro, Rats, Drug Discovery, Molecular Medicine, Animals, Humans, Serotonin Antagonists, Pharmacophore, Reuptake inhibitor, Molecular Biology, 5-HT receptor, Selective Serotonin Reuptake Inhibitors, Pyrans

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b65648ac8ef4136a944f2c2cc5d3e279
https://pubmed.ncbi.nlm.nih.gov/15388156

المؤلفون: Matthew John Valli, James A. Monn, Ann E. Kingston, Bryan G. Johnson, Darryle D. Schoepp, Rebecca A. Wright, Rosemarie Tomlinson

المصدر: Bioorganicmedicinal chemistry letters. 8(15)

مصطلحات موضوعية: Proline, Chemistry, Metabotropic glutamate receptor 5, Stereochemistry, Metabotropic glutamate receptor 4, Hydrolysis, Organic Chemistry, Clinical Biochemistry, Metabotropic glutamate receptor 7, Pharmaceutical Science, Stereoisomerism, Receptors, Metabotropic Glutamate, Biochemistry, Recombinant Proteins, HYDIA, Structure-Activity Relationship, Phosphatidylinositol Phosphates, APICA, Drug Discovery, Molecular Medicine, Metabotropic glutamate receptor 1, Humans, Metabotropic glutamate receptor 3, Metabotropic glutamate receptor 2, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63857b44aafaff1ce740e68efeb0d38e
https://pubmed.ncbi.nlm.nih.gov/9873471

المؤلفون: A.E. Kingston, Barry Peter Clark, J. Lowndes, David Lodge, Nancy Gail Mayne, N. Evans, J.P. Burnett, S.L. Cockerham, Rosemarie Tomlinson

المصدر: Neuropharmacology. 37(3)

مصطلحات موضوعية: Agonist, medicine.drug_class, Receptor, Metabotropic Glutamate 5, Glutamic Acid, Cysteic acid, Biology, Phosphatidylinositols, Receptors, Metabotropic Glutamate, Cell Line, Glutamate receptor binding, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Cricetinae, medicine, Serine, Animals, Humans, Cysteine, Receptor, Homocysteine, Cysteic Acid, Pharmacology, chemistry.chemical_classification, Neurotransmitter Agents, Mesocricetus, Molecular biology, Amino acid, Amino Acids, Sulfur, Biochemistry, chemistry, Metabotropic glutamate receptor, Metabotropic glutamate receptor 1

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d0255ea8c728242399d1d5943d348f
https://pubmed.ncbi.nlm.nih.gov/9681926

المؤلفون: John Goldsworthy, Barry Peter Clark, Nancy Gail Mayne, Rosemarie Tomlinson, David M. Lodge, John Richard Harris, A.E. Kingston, J.P. Burnett

المصدر: Neuropharmacology. 35:A17

مصطلحات موضوعية: Pharmacology, Cellular and Molecular Neuroscience, business.industry, Medicine, Human group, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5d839cb9cac7624a08651c89377df04d
https://doi.org/10.1016/0028-3908(96)84713-7