المؤلفون: Kundert, K, Lucas, JE, Watters, KE, Fellmann, C, Ng, AH, Heineike, BM, Fitzsimmons, CM, Oakes, BL, Qu, J, Prasad, N, Rosenberg, OS, Savage, DF, El-Samad, H, Doudna, JA, Kortemme, T

المصدر: Nature communications. 10(1)

مصطلحات موضوعية: DNA, RNA, Guide, Ligands, Aptamers, Nucleotide, CRISPR-Cas Systems, Gene Editing, CRISPR-Associated Protein 9, Biochemistry and Cell Biology, Physical Sciences, Biological Sciences, Biotechnology, Genetics, Generic health relevance, RNA, Guide, Kinetoplastida

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/3t52t2n5

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المؤلفون: Alanizi AA; Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States., Sorlin AM; Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States., Parker MFL; Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States.; Department of Psychiatry, Renaissance School of Medicine at Stony Brook University, Stony Brook, New York 11794, United States., López-Álvarez M; Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States., Qin H; Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States., Lee SH; Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States., Blecha J; Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States., Rosenberg OS; Department of Medicine, University of California, San Francisco, San Francisco, California 94158, United States., Engel J; Department of Medicine, University of California, San Francisco, San Francisco, California 94158, United States., Ohliger MA; Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States.; Department of Radiology, Zuckerberg San Francisco General Hospital, San Francisco, California 94110, United States., Flavell RR; Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States., Wilson DM; Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States.

المصدر: Bioconjugate chemistry [Bioconjug Chem] 2024 Apr 17; Vol. 35 (4), pp. 517-527. Date of Electronic Publication: 2024 Mar 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9010319 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4812 (Electronic) Linking ISSN: 10431802 NLM ISO Abbreviation: Bioconjug Chem Subsets: MEDLINE

مواضيع طبية MeSH: Azides*/chemistry , Peptidoglycan*, Humans ; Animals ; Mice ; Tissue Distribution ; Positron-Emission Tomography ; Bacteria ; Amino Acids ; Alanine ; Fluorine Radioisotopes/chemistry

المؤلفون: Yu MA; Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California, San Francisco, CA, USA., Banta AB; Pharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison, Madison, WI, USA.; Great Lakes Bioenergy Research Center, Wisconsin Energy Institute, University of Wisconsin-Madison, Madison, WI, USA., Ward RD; Pharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison, Madison, WI, USA.; Laboratory of Genetics, University of Wisconsin-Madison, Madison, WI, USA., Prasad NK; Chan Zuckerberg Biohub, San Francisco, CA, USA.; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA., Kwon MS; Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California, San Francisco, CA, USA., Rosenberg OS; Chan Zuckerberg Biohub, San Francisco, CA, USA.; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.; Department of Biochemistry and Biophysics, University of California, San Francisco, CA, USA., Peters JM; Pharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison, Madison, WI, USA. jason.peters@wisc.edu.; Great Lakes Bioenergy Research Center, Wisconsin Energy Institute, University of Wisconsin-Madison, Madison, WI, USA. jason.peters@wisc.edu.; Department of Bacteriology, University of Wisconsin-Madison, Madison, WI, USA. jason.peters@wisc.edu.; Department of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, WI, USA. jason.peters@wisc.edu.

المصدر: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2024; Vol. 2721, pp. 13-32.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029 (Electronic) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE

مواضيع طبية MeSH: Pseudomonas aeruginosa*/genetics , CRISPR-Cas Systems*, Animals ; Mice ; Clustered Regularly Interspaced Short Palindromic Repeats ; Gene Silencing ; Phenotype

المؤلفون: Sunshine S; Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, USA., Puschnik AS; Chan Zuckerberg Biohub, San Francisco, San Francisco, CA, USA., Replogle JM; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA.; Whitehead Institute for Biomedical Research, Cambridge, MA, USA., Laurie MT; Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, USA., Liu J; Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, USA.; University of California, Berkeley-UCSF Joint Graduate Program in Bioengineering, San Francisco, CA, USA., Zha BS; Department of Medicine, Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California, San Francisco, San Francisco, CA, USA., Nuñez JK; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA.; Department of Molecular & Cell Biology, University of California, Berkeley, Berkeley, CA, USA., Byrum JR; Chan Zuckerberg Biohub, San Francisco, San Francisco, CA, USA., McMorrow AH; Chan Zuckerberg Biohub, San Francisco, San Francisco, CA, USA., Frieman MB; Department of Microbiology and Immunology, Center for Pathogen Research, University of Maryland School of Medicine, Baltimore, MD, USA., Winkler J; Department of Cell and Tissue Biology, University of California, San Francisco, San Francisco, CA, USA.; Center for Cancer Research, Medical University of Vienna, Vienna, Austria., Qiu X; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, USA., Rosenberg OS; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA., Leonetti MD; Chan Zuckerberg Biohub, San Francisco, San Francisco, CA, USA., Ye CJ; Division of Rheumatology, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.; Institute of Human Genetics, University of California San Francisco, San Francisco, CA, USA.; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA.; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA.; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA., Weissman JS; Whitehead Institute for Biomedical Research, Cambridge, MA, USA. weissman@wi.mit.edu.; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, USA. weissman@wi.mit.edu.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA. weissman@wi.mit.edu.; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA. weissman@wi.mit.edu., DeRisi JL; Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, USA. joe@derisilab.ucsf.edu.; Chan Zuckerberg Biohub, San Francisco, San Francisco, CA, USA. joe@derisilab.ucsf.edu., Hein MY; Chan Zuckerberg Biohub, San Francisco, San Francisco, CA, USA. marco.hein@maxperutzlabs.ac.at.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA. marco.hein@maxperutzlabs.ac.at.; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA. marco.hein@maxperutzlabs.ac.at.; Max Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, Austria. marco.hein@maxperutzlabs.ac.at.; Medical University of Vienna, Center for Medical Biochemistry, Vienna, Austria. marco.hein@maxperutzlabs.ac.at.

المصدر: Nature communications [Nat Commun] 2023 Oct 06; Vol. 14 (1), pp. 6245. Date of Electronic Publication: 2023 Oct 06.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: SARS-CoV-2*/genetics , COVID-19*/genetics, Humans ; Proteomics ; Lung ; Epithelial Cells

المؤلفون: Parker MFL; Department of Radiology and Biomedical Imaging, University of California, San Francisco.; Department of Psychiatry, Renaissance School of Medicine at Stony Brook University, New York., López-Álvarez M; Department of Radiology and Biomedical Imaging, University of California, San Francisco., Alanizi AA; Department of Radiology and Biomedical Imaging, University of California, San Francisco., Luu JM; Department of Radiology and Biomedical Imaging, University of California, San Francisco., Polvoy I; Department of Radiology and Biomedical Imaging, University of California, San Francisco., Sorlin AM; Department of Radiology and Biomedical Imaging, University of California, San Francisco., Qin H; Department of Radiology and Biomedical Imaging, University of California, San Francisco., Lee S; Department of Radiology and Biomedical Imaging, University of California, San Francisco., Rabbitt SJ; Department of Radiology and Biomedical Imaging, University of California, San Francisco., Pichardo-González PA; Department of Radiology and Biomedical Imaging, University of California, San Francisco., Ordonez AA; Center for Infection and Inflammation Imaging Research, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland., Blecha J; Department of Radiology and Biomedical Imaging, University of California, San Francisco., Rosenberg OS; Department of Medicine, University of California, San Francisco., Flavell RR; Department of Radiology and Biomedical Imaging, University of California, San Francisco., Engel J; Department of Medicine, University of California, San Francisco.; UCSF Department of Microbiology and Immunology, San Francisco, California., Jain SK; Center for Infection and Inflammation Imaging Research, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland., Ohliger MA; Department of Radiology and Biomedical Imaging, University of California, San Francisco.; Department of Radiology, Zuckerberg San Francisco General Hospital, San Francisco, California., Wilson DM; Department of Radiology and Biomedical Imaging, University of California, San Francisco.

المصدر: The Journal of infectious diseases [J Infect Dis] 2023 Oct 03; Vol. 228 (Suppl 4), pp. S281-S290.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0413675 Publication Model: Print Cited Medium: Internet ISSN: 1537-6613 (Electronic) Linking ISSN: 00221899 NLM ISO Abbreviation: J Infect Dis Subsets: MEDLINE

مواضيع طبية MeSH: Discitis*/diagnostic imaging , Staphylococcal Infections*/diagnostic imaging , Osteomyelitis*/microbiology, Humans ; Rats ; Animals ; 4-Aminobenzoic Acid ; Escherichia coli ; Positron-Emission Tomography/methods ; Bacteria ; Staphylococcus aureus ; Radiopharmaceuticals

المؤلفون: Sorlin AM; Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States., López-Álvarez M; Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States., Rabbitt SJ; Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States., Alanizi AA; Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States., Shuere R; Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States., Bobba KN; Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States., Blecha J; Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States., Sakhamuri S; Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States., Evans MJ; Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States., Bayles KW; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska 68198, United States., Flavell RR; Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States., Rosenberg OS; Department of Medicine University of California, San Francisco, San Francisco, California 94158, United States., Sriram R; Department of Biotechnology, Ghent University, Gent B-9000, Belgium., Desmet T; Department of Biotechnology, Ghent University, Gent B-9000, Belgium., Nidetzky B; Institute of Biotechnology and Biochemical Engineering, Graz University of Technology, Graz 8010, Austria., Engel J; Department of Biotechnology, Ghent University, Gent B-9000, Belgium., Ohliger MA; Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States.; Department of Radiology Zuckerberg San Francisco General Hospital, San Francisco, California 94110, United States., Fraser JS; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, California 94158, United States., Wilson DM; Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States.

المصدر: Journal of the American Chemical Society [J Am Chem Soc] 2023 Aug 16; Vol. 145 (32), pp. 17632-17642. Date of Electronic Publication: 2023 Aug 03.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE

مواضيع طبية MeSH: Fluorodeoxyglucose F18* , Trehalose*, Humans ; Cellobiose ; Staphylococcus aureus ; Positron-Emission Tomography/methods ; Bacteria